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Gene: Mkx (mohawk homeobox) Rattus norvegicus
Symbol: Mkx
Name: mohawk homeobox
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and RNA polymerase II transcription factor binding activity. Predicted to be involved in several processes, including collagen fibril organization; regulation of transcription by RNA polymerase II; and tendon development. Predicted to localize to the nucleus. Orthologous to human MKX (mohawk homeobox); INTERACTS WITH 17beta-estradiol; bisphenol A; (-)-epigallocatechin 3-gallate (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: homeobox protein Mohawk; iroquois homeobox protein-like 1; Irxl1; LOC291228; RGD1305652; similar to hypothetical protein MGC39616
Homo sapiens (human) : MKX (mohawk homeobox)  HGNC  Alliance
Mus musculus (house mouse) : Mkx (mohawk homeobox)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mkx (mohawk homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : MKX (mohawk homeobox)
Canis lupus familiaris (dog) : MKX (mohawk homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mkx (mohawk homeobox)
Sus scrofa (pig) : MKX (mohawk homeobox)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01760,537,615 - 60,553,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,537,935 - 60,549,750 (+)Ensembl
Rnor_5.01762,321,329 - 62,332,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,631,540 - 63,710,138 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11763,642,477 - 63,722,172 (-)NCBI
Celera1756,416,753 - 56,495,058 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mkx
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305652
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.