Slc30a10 (solute carrier family 30, member 10)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Community Projects Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Slc30a10 (solute carrier family 30, member 10) Rattus norvegicus

Analyze

Symbol:

Slc30a10

Name:

solute carrier family 30, member 10

RGD ID:

1305098

Description:

Predicted to enable calcium:manganese antiporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in several processes, including detoxification of zinc ion; intracellular monoatomic cation homeostasis; and monoatomic cation transmembrane transport. Predicted to act upstream of or within epidermal growth factor receptor signaling pathway. Predicted to be located in Golgi apparatus; endosome membrane; and plasma membrane. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 1. Orthologous to human SLC30A10 (solute carrier family 30 member 10); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

calcium/manganese antiporter SLC30A10; LOC289353; RGD1305098; similar to hypothetical protein DKFZp547M236; zinc transporter 10

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC30A10 (solute carrier family 30 member 10)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc30a10 (solute carrier family 30, member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc30a10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC30A10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC30A10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC30A10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC30A10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc30a10 (solute carrier family 30 member 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Slc30a10 (solute carrier family 30, member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC30A10 (solute carrier family 30 member 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc30a10 (solute carrier family 30 member 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	COT1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	ZnT63C	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	cdf-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ZRC1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc30a10	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Allele / Splice:

Slc30a10^em1Sommu

Genetic Models:

CD-Slc30a10^em1Sommu

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	96,998,143 - 97,048,076 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	96,998,143 - 97,009,103 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	99,497,741 - 99,509,009 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	100,903,238 - 100,914,198 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	98,080,008 - 98,091,280 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	103,396,295 - 103,406,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	103,396,314 - 103,410,363 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	108,048,948 - 108,083,821 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	101,474,867 - 101,492,180 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	101,664,109 - 101,681,195 (+)	NCBI
Celera	13	96,511,232 - 96,522,472 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cholestasis (ISO)

dystonia (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

hypermanganesemia with dystonia 1 (ISO)

hypothyroidism (ISO)

liver cirrhosis (ISO)

Loeys-Dietz syndrome 4 (ISO)

Manganese Poisoning (ISO)

Martsolf Syndrome (ISO)

parathyroid carcinoma (ISO)

Parkinson's disease (ISO)

Parkinsonism (ISO)

polycythemia (ISO)

Usher syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-trinitrobenzenesulfonic acid (ISO)

3-Iodothyronamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

ciglitazone (ISO)

copper(II) sulfate (ISO)

curcumin (ISO)

cyclosporin A (ISO)

dibenz[a,h]anthracene (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

ethylenediaminetetraacetic acid (ISO)

folic acid (ISO)

furan (ISO)

GW 501516 (ISO)

isotretinoin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

p-toluidine (EXP)

paracetamol (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

quinolin-8-ol (ISO)

reactive oxygen species (EXP)

resveratrol (ISO)

rifampicin (ISO)

ritodrine (ISO)

rotenone (EXP)

SB 431542 (ISO)

senecionine (ISO)

sodium arsenite (ISO)

testosterone (EXP,ISO)

tetrachloroethene (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thyroxine (ISO)

trichostatin A (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (EXP,ISO)

zinc(0) (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to angiotensin (ISO)

detoxification of zinc ion (IBA)

epidermal growth factor receptor signaling pathway (ISO)

intracellular copper ion homeostasis (ISO)

intracellular manganese ion homeostasis (ISO)

intracellular zinc ion homeostasis (IBA,ISO)

manganese ion export across plasma membrane (ISO)

manganese ion homeostasis (ISO)

manganese ion transport (IBA,ISO)

positive regulation of ERK1 and ERK2 cascade (ISO)

zinc ion import into organelle (ISO)

zinc ion transmembrane transport (IBA)

Cellular Component

early endosome (ISO)

early endosome membrane (ISO)

Golgi apparatus (ISO)

plasma membrane (ISO)

recycling endosome (ISO)

recycling endosome membrane (ISO)

synaptic vesicle (ISO)

Molecular Function

calcium:manganese antiporter activity (ISO)

manganese ion transmembrane transporter activity (ISO)

protein binding (ISO)

zinc ion transmembrane transporter activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22341972	PMID:22427991	PMID:25319704	PMID:26728129

Genomics

Comparative Map Data

Slc30a10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	96,998,143 - 97,048,076 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	96,998,143 - 97,009,103 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	99,497,741 - 99,509,009 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	100,903,238 - 100,914,198 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	98,080,008 - 98,091,280 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	103,396,295 - 103,406,759 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	103,396,314 - 103,410,363 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	108,048,948 - 108,083,821 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	101,474,867 - 101,492,180 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	101,664,109 - 101,681,195 (+)	NCBI
Celera	13	96,511,232 - 96,522,472 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

SLC30A10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	219,910,445 - 219,959,098 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	219,685,427 - 219,959,018 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	220,083,787 - 220,132,440 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	218,154,229 - 218,168,616 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	193,307,088 - 193,321,437 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	190,762,978 - 190,777,364 (-)	NCBI		HuRef
CHM1_1	1	221,360,934 - 221,375,280 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	219,148,333 - 219,196,857 (-)	NCBI		T2T-CHM13v2.0

Slc30a10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	185,187,045 - 185,200,959 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	185,187,045 - 185,200,959 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	185,454,848 - 185,468,762 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	185,454,848 - 185,468,762 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	187,278,727 - 187,292,641 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	187,155,636 - 187,169,550 (+)	NCBI		MGSCv36	mm8
Celera	1	192,408,431 - 192,422,120 (+)	NCBI		Celera
Cytogenetic Map	1	H5	NCBI
cM Map	1	89.53	NCBI

Slc30a10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955520	3,631,192 - 3,641,595 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC30A10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	29,419,410 - 29,464,618 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	195,480,707 - 195,528,243 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	200,521,746 - 200,536,317 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	200,522,554 - 200,566,228 (-)	Ensembl	panpan1.1		panPan2

SLC30A10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	14,705,517 - 14,746,835 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	14,709,866 - 14,747,540 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	14,748,635 - 14,789,627 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	14,742,854 - 14,784,066 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	14,734,379 - 14,784,507 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	14,752,051 - 14,793,083 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	15,096,305 - 15,111,010 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	15,407,944 - 15,427,303 (-)	NCBI		UU_Cfam_GSD_1.0

SLC30A10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	9,527,523 - 9,545,493 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	11,611,255 - 11,651,498 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC30A10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	9,654,846 - 9,671,247 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	9,655,129 - 9,668,280 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	9,932,951 - 9,979,601 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc30a10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	3,598,260 - 3,611,307 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	3,598,375 - 3,612,165 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc30a10
296 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	214
Count of miRNA genes:	159
Interacting mature miRNAs:	167
Transcripts:	ENSRNOT00000049499
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat

Markers in Region

AW522618

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	13	108,068,398 - 108,068,488	UniSTS	Rnor5.0
RGSC_v3.4	13	101,471,485 - 101,471,575	UniSTS	RGSC3.4
Celera	13	96,507,686 - 96,507,776	UniSTS
RH 3.4 Map	13	657.9	UniSTS
Cytogenetic Map	13	q26	UniSTS

UniSTS:547077

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Celera	13	96,511,185 - 96,512,753	UniSTS
Cytogenetic Map	13	q26	UniSTS

Genetic Models

This gene Slc30a10 is modified in the following models/strains:

CD-Slc30a10^em1Sommu

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	6	41	41	1	41			58
Low	1	8	10		16		1	1	16	2	18	2	1
Below cutoff		16	6		2		4	4		26	20	8	4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000049499 ⟹ ENSRNOP00000050013

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	96,998,143 - 97,009,103 (+)	Ensembl
Rnor_6.0 Ensembl	13	103,396,314 - 103,410,363 (+)	Ensembl

RefSeq Acc Id:

NM_001105985 ⟹ NP_001099455

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	96,998,143 - 97,009,103 (+)	NCBI
Rnor_6.0	13	103,396,295 - 103,406,759 (+)	NCBI
Rnor_5.0	13	108,048,948 - 108,083,821 (+)	NCBI
RGSC_v3.4	13	101,474,867 - 101,492,180 (+)	RGD
Celera	13	96,511,232 - 96,522,472 (+)	RGD

Sequence:

show sequence

AAATCAGGCTTGGGCGGCGAGGGAGGAGGGGCAGGGGCCCCGGGAGGTGCCCTTTGCGACTCTG
GGGCCACTCCTGCAGACTCTGGTCCCGCGAGCGCGAGCTAGTGGCATAAAAGGCCCGGGAGGGT
AAGGGCGGGCCTGCCGCCGGAGGTGGGCTCCAGACCCCCGCAACCTGTTGCGGGGCTCAGCGGG
CTGTAAAGATGGGCCGTTATTCGGGCAAGACCTGTCGGCTGCTGTTCATGCTGGTGCTCACCGC
GGCCTTCTTCGTGGCCGAACTGGTGTCGGGTTACCTGGGCAACTCCATCGCGCTGCTCTCGGAC
TCGTTCAACATGCTGTCTGATCTGATCTCGCTGTGCGTGGGCCTGGGCTCCGGCTACATCGCGC
GACGCGGTCCCCGCGGCTCCAGCGCCACCTACGGCTATGTGCGGGCGGAGGTGGTGGGCGCGCT
CAGCAACGCAGTCTTCCTCACCGCGCTCTGCTTTACCATCTTCGTGGAGGCCGTGTTGCGGCTC
GCGCGGCCCGAGCGCATCGACGACCCGGAGCTGGTACTCATCGTGGGCGCCCTGGGGCTGGCAG
TCAACGTGGTGGGGCTGCTCATCTTCCAGGACTGCGGCGCCTGCTTCTCCCGCTGCACGCGGGG
TCACCGGACCCGCCCTTCGCAGCCGCCGCGCCAGGGGGACACTGGTGGCGCTTTGGGGTGTCCC
CGGGAGGCTGCGACAGCCACAGACCCCGGCTCAGACTCAGCAGTGACTCTCCGGGGGGCCTCGG
CCGGAAGAAAGCAGCAGGAGGGCGCGACGGTGTTCTCGAATGTAGCAGGTGATTCCCTGAACAC
CCAGAATGAACCAGAAGAGACAACAAAAAAGGAGAAGAAGTCTGAAGCACTGAATATCAGAGGT
GTTCTTTTGCATGTGATGGGAGATGCCCTGGGGTCCGTGATTGTGGTTGTCACAGCCATCATAT
TCTATGTTCGTCCCCTGAGACATGAAGACCCGTGTAACTGGCAATGCTACATTGACCCCAGTTT
GACTGTTGTCATGGTCATCATTATCTTATCATCAGCCTTTCCACTCATCAAGGAGACTGCTGTC
ATCCTGCTGCAGATGGTTCCCAAGGGAGTCAACATGGAGGAGCTGATGAGCCAGCTGTCTATGG
TGCCTGGGGTTAGCAGTGTGCATGAAGTGCACATCTGGGAACTGATAAGTGGGAAGGTTATTGC
CACCTTGCACATCAAGCACCAGGAGGGCACGGAATACCAGGATGCCAGCAGAAAAGTCCGCGAG
ATCTTCCACCATGCAGGAATCCACAACGTGACCATCCAGTTTGAAACATTGGACTTGAAGGAAG
CCCTGGAGCAGAAGGACTTCTTGCCAACCTGCAGTGCACCCTGCATCTCCCAGAGTTGCGCTAA
GAAGCTCTGCTGTCCCCCGGGGACACTGCCTCTGGCTCTCGTCAATGGTTGTGCAGAGCACAAT
GGTGGGCCCAATCTAGAGTCTTACCGAAGCATAGAAGCTCCAGAAGTGGTCATAGATGTGGCTT
TGGATGGCTGTCCAAGGAAGCAAGGACAGGTTCACAGCAAGACTCAAGAGAGACAGCATTGTGA
AAACAGCACTCATTTTTAGTGGGTTCCCACACAAATCAAACAGTCTAAACAGACACTTTGGTGT
CACTGGCTCTGCTTGTGGGAAGAGCTCTGTGGATGTGTATCCTGTCAGTAGGGGTCAGCCATTT
GAGATGTTAGTGGAACAAGCCTGCTGATTTTCATGTGGTGGATAACCCCTTTCCAGTACTCTGG
GCATCTCATGGTTCTCTGTGACAGTTTCAGTACGGATATGAATTTCCTAAAGCAGACTGCCCTA
GTGTATATATCAGGAGTGTTGAAGGGCTCAGCAACTATGACAGGGGACATGAAGTAGGTCTTGT
CTGTCTTGTGGTGCTGGGGAATTGCATACAGGGCTCGTGCGTGCTAAGGAACTGCTCTGTTACC
GAGATGAACTCTGTATGTAGCCTTTGTTTTCAAACACATCAGAACTTCTAGTTGACTCTCAGGT
GAGCTCAAAGCTTACGTGGGTAGAAAAGCAGTTAAGCACCTTAACTATGTTTTCCTCTCTTCCC
CTCAAAGATCATAAAAGATGAACATCAGGTTTTCGTGGCCCTGCAGAAACATATATTCTTAAGT
CCATTCTTGGACCACGAGAAACAGACACCTAATAAATAAATTCAAGATGCATAGTTATTAAGAT
GGA

hide sequence

RefSeq Acc Id:

XM_039090583 ⟹ XP_038946511

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	96,998,263 - 97,033,527 (+)	NCBI

RefSeq Acc Id:

XM_039090584 ⟹ XP_038946512

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	96,998,263 - 97,048,076 (+)	NCBI

RefSeq Acc Id:

XM_039090585 ⟹ XP_038946513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	96,998,263 - 97,006,757 (+)	NCBI

RefSeq Acc Id:

XR_005492229

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	96,998,263 - 96,999,748 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099455	(Get FASTA)	NCBI Sequence Viewer
	XP_038946511	(Get FASTA)	NCBI Sequence Viewer
	XP_038946512	(Get FASTA)	NCBI Sequence Viewer
	XP_038946513	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL94925	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000050013
	ENSRNOP00000050013.2

RefSeq Acc Id:

NP_001099455 ⟸ NM_001105985

- UniProtKB:

D3ZJB7 (UniProtKB/TrEMBL), A6JGR9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGRYSGKTCRLLFMLVLTAAFFVAELVSGYLGNSIALLSDSFNMLSDLISLCVGLGSGYIARRG
PRGSSATYGYVRAEVVGALSNAVFLTALCFTIFVEAVLRLARPERIDDPELVLIVGALGLAVNV
VGLLIFQDCGACFSRCTRGHRTRPSQPPRQGDTGGALGCPREAATATDPGSDSAVTLRGASAGR
KQQEGATVFSNVAGDSLNTQNEPEETTKKEKKSEALNIRGVLLHVMGDALGSVIVVVTAIIFYV
RPLRHEDPCNWQCYIDPSLTVVMVIIILSSAFPLIKETAVILLQMVPKGVNMEELMSQLSMVPG
VSSVHEVHIWELISGKVIATLHIKHQEGTEYQDASRKVREIFHHAGIHNVTIQFETLDLKEALE
QKDFLPTCSAPCISQSCAKKLCCPPGTLPLALVNGCAEHNGGPNLESYRSIEAPEVVIDVALDG
CPRKQGQVHSKTQERQHCENSTHF

hide sequence

RefSeq Acc Id:

ENSRNOP00000050013 ⟸ ENSRNOT00000049499

RefSeq Acc Id:	XP_038946512 ⟸ XM_039090584
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946511 ⟸ XM_039090583
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946513 ⟸ XM_039090585
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZJB7-F1-model_v2	AlphaFold	D3ZJB7	1-472	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699093

Promoter ID:

EPDNEW_R9618

Type:

initiation region

Name:

Slc30a10_1

Description:

solute carrier family 30, member 10

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	103,396,372 - 103,396,432	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305098	AgrOrtholog
BioCyc Gene	G2FUF-16970	BioCyc
Ensembl Genes	ENSRNOG00000002397	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000049499	ENTREZGENE
	ENSRNOT00000049499.4	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1510.10	UniProtKB/TrEMBL
InterPro	Cation_efflux	UniProtKB/TrEMBL
	Cation_efflux_TMD	UniProtKB/TrEMBL
KEGG Report	rno:289353	UniProtKB/TrEMBL
NCBI Gene	289353	ENTREZGENE
PANTHER	FI23527P1	UniProtKB/TrEMBL
	ZINC TRANSPORTER 10	UniProtKB/TrEMBL
Pfam	Cation_efflux	UniProtKB/TrEMBL
PhenoGen	Slc30a10	PhenoGen
RatGTEx	ENSRNOG00000002397	RatGTEx
Superfamily-SCOP	SSF161111	UniProtKB/TrEMBL
UniProt	A6JGR9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZJB7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Slc30a10	solute carrier family 30, member 10	Slc30a10_predicted	solute carrier family 30, member 10 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Slc30a10_predicted	solute carrier family 30, member 10 (predicted)	RGD1305098_predicted	similar to hypothetical protein DKFZp547M236 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1305098_predicted	similar to hypothetical protein DKFZp547M236 (predicted)	LOC289353_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289353_predicted	similar to hypothetical protein DKFZp547M236 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM