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Gene: Pkd1 (polycystin 1, transient receptor potential channel interacting) Rattus norvegicus
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Symbol: Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Description: Predicted to have several functions, including Wnt-activated receptor activity; calcium channel activity; and ion channel binding activity. Involved in positive regulation of cytosolic calcium ion concentration. Localizes to the Golgi apparatus and lateral plasma membrane. Used to study polycystic kidney disease. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; intracranial aneurysm; and polycystic kidney disease 1. Orthologous to human PKD1 (polycystin 1, transient receptor potential channel interacting); INTERACTS WITH 2-acetamidofluorene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: polycystic kidney disease 1; polycystic kidney disease 1 homolog; polycystic kidney disease 1 homolog (human); polycystin 1; polycystin-1
Orthologs:
Allele / Splice: Pkd1em2Mcwi   Pkd1em3Mcwi   Pkd1em1Mcwi   Pkd1em6Mcwi  
Genetic Models: LEW-Pkd1em2Mcwi LEW-Pkd1em6Mcwi LEW-Pkd1em1Mcwi LEW-Pkd1em3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01013,914,057 - 13,962,008 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01013,731,035 - 13,778,993 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,801,445 - 13,848,212 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,801,471 - 13,848,236 (+)NCBI
Celera1013,254,601 - 13,301,131 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pkd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3333
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-06-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.