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Strain Registration

Strain: SS-Cacna1hem2Mcwi

Symbol: SS-Cacna1hem2Mcwi
Strain: SS-Cacna1hem2
Substrain: Mcwi
RGD ID: 6484717
Citation ID: RRID:RGD_6484717
Ontology ID: RS:0003286
Alleles: Cacna1hem2Mcwi
Also Known As: SS-Cacna1hem2Mcwi; SS-Cacna1h^[em2Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CCGACCCACAGTGTCtgggagATCGTGGGGCAGGCAGAC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion in exon 11.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21014,390,104 - 14,448,204RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01014,744,474 - 14,744,487RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01014,547,456 - 14,605,627RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41014,621,372 - 14,679,051RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Cacna1hem2Mcwi-var1 chr10 14744474 14744487 ACGATCTCCCAGAC - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-03 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Symbol updated 68687 APPROVED
2014-04-03 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Symbol updated 68687 APPROVED
2014-04-03 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Name updated 68913 APPROVED
2014-04-03 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Cacna1hem2Mcwi    SS-Cacna1hem2Mcwi    Name updated 68913 APPROVED