RGD Reference Report - Knockout rats via embryo microinjection of zinc-finger nucleases. - Rat Genome Database

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Knockout rats via embryo microinjection of zinc-finger nucleases.

Authors: Geurts, AM  Cost, GJ  Freyvert, Y  Zeitler, B  Miller, JC  Choi, VM  Jenkins, SS  Wood, A  Cui, X  Meng, X  Vincent, A  Lam, S  Michalkiewicz, M  Schilling, R  Foeckler, J  Kalloway, S  Weiler, H  Menoret, S  Anegon, I  Davis, GD  Zhang, L  Rebar, EJ  Gregory, PD  Urnov, FD  Jacob, HJ  Buelow, R 
Citation: Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
RGD ID: 4131263
Pubmed: (View Article at PubMed) PMID:19628861
DOI: Full-text: DOI:10.1126/science.1172447

The toolbox of rat genetics currently lacks the ability to introduce site-directed, heritable mutations into the genome to create knockout animals. By using engineered zinc-finger nucleases (ZFNs) designed to target an integrated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a single injection of DNA or messenger RNA encoding ZFNs into the one-cell rat embryo leads to a high frequency of animals carrying 25 to 100% disruption at the target locus. These mutations are faithfully and efficiently transmitted through the germline. Our data demonstrate the feasibility of targeted gene disruption in multiple rat strains within 4 months time, paving the way to a humanized monoclonal antibody platform and additional human disease models.

Annotation

Objects referenced in this article
Gene Abcb1bem2Mcwi ATP-binding cassette, subfamily B (MDR/TAP), member 1B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Acad10em2Mcwi acyl-Coenzyme A dehydrogenase family, member 10; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Aceem1Mcwi angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Aceem2Mcwi angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Strain ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/EurMcwi-Asipem1Mcwi null Rattus norvegicus
Gene Adipoqem1Mcwi adiponectin, C1Q and collagen domain containing; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Adipoqem2Mcwi adiponectin, C1Q and collagen domain containing; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Adora2bem1Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Adora2bem2Mcwi adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Adra2aem1Mcwi adrenergic, alpha-2A-, receptor; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Agtr1aem1Mcwi angiotensin II receptor, type 1a; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Agtr1aem5Mcwi angiotensin II receptor, type 1a; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Agtrapem4Mcwi angiotensin II receptor-associated protein; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Agtrapem8Mcwi angiotensin II receptor-associated protein; zinc finger nuclease induced mutant 8, Medical College of Wisconsin Rattus norvegicus
Gene Aldh2em2Mcwi aldehyde dehydrogenase 2 family (mitochondrial); zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Alms1em1Mcwi Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Apoeem7Mcwi apolipoprotein E; zinc finger nuclease induced mutant 7, Medical College of Wisconsin Rattus norvegicus
Gene Apoeem8Mcwi apolipoprotein E; zinc finger nuclease induced mutant 8, Medical College of Wisconsin Rattus norvegicus
Gene Apoeem9Mcwi apolipoprotein E; zinc finger nuclease induced mutant 9, Medical College of Wisconsin Rattus norvegicus
Gene Asipem1Mcwi agouti signaling protein; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Atp2b1em2Mcwi ATPase, Ca++ transporting, plasma membrane 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Strain BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em1Mcwi null Rattus norvegicus
Strain BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em2Mcwi null Rattus norvegicus
Strain BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi-Il1r1em3Mcwi null Rattus norvegicus
Gene Bcas3em4Mcwi breast carcinoma amplified sequence 3; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Bcat1em2Mcwi branched chain amino acid transaminase 1, cytosolic; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Cacna1hem2Mcwi calcium channel, voltage-dependent, T type, alpha 1H subunit; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Cd247em1Mcwi Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cd247em3Mcwi Cd247 molecule; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Cd247em5Mcwi Cd247 molecule; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Cdh13em1Mcwi cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Clcn6em2Mcwi chloride channel 6; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Comtem1Mcwi catechol-O-methyltransferase; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cst3em1Mcwi cystatin C; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cst3em3Mcwi cystatin C; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Cubnem1Mcwi cubilin (intrinsic factor-cobalamin receptor) ; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cybaem1Mcwi cytochrome b-245 alpha chain; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cyp1a1em1Mcwi cytochrome P450, family 1, subfamily a, polypeptide 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cyp1a1em2Mcwi cytochrome P450, family 1, subfamily a, polypeptide 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Cyp1a1em5Mcwi cytochrome P450, family 1, subfamily a, polypeptide 1; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Cyp4a2em1Mcwi cytochrome P450, family 4, subfamily a, polypeptide 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Cyp4a3em3Mcwi cytochrome P450, family 4, subfamily a, polypeptide 3; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Strain DA-Tph2em2Mcwi null Rattus norvegicus
Strain DA-Tph2em3Mcwi null Rattus norvegicus
Gene Dguokem1Mcwi deoxyguanosine kinase; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Dguokem2Mcwi deoxyguanosine kinase; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Dguokem3Mcwi deoxyguanosine kinase; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Dguokem4Mcwi deoxyguanosine kinase; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Ets1em1Mcwi v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Fahem3Mcwi fumarylacetoacetate hydrolase; TALEN induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Fgf1em2Mcwi fibroblast growth factor 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Fgf5em1Mcwi fibroblast growth factor 5; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Fgf5em5Mcwi fibroblast growth factor 5; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Strain FHH-Chr 1BN-Sorcs1em1Mcwi+/+ FHH-Chr 1BN-Sorcs1em1Mcwi+/Sorcs1em1Mcwi+ Rattus norvegicus
Strain FHH-Chr 1BN-Sorcs1em1Mcwi-/- FHH-Chr 1BN-Sorcs1em1Mcwi-/Sorcs1em1Mcwi- Rattus norvegicus
Strain FHH-Chr 1BN-Sorcs1em1Mcwi null Rattus norvegicus
Strain FHH-Chr 1BN-Sorcs3em1Mcwi null Rattus norvegicus
Strain FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+ FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/Rab38em1Mcwi+ Rattus norvegicus
Strain FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/- FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi- Rattus norvegicus
Strain FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi null Rattus norvegicus
Gene Fynem1Mcwi FYN oncogene related to SRC, FGR, YES; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Fynem6Mcwi FYN oncogene related to SRC, FGR, YES; zinc finger nuclease induced mutant 6, Medical College of Wisconsin Rattus norvegicus
Gene Gnb3em1Mcwi guanine nucleotide binding protein (G protein), beta polypeptide 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Gpr183em1Mcwi G protein-coupled receptor 183; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Gpr183em2Mcwi G protein-coupled receptor 183; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Gpr183em3Mcwi G protein-coupled receptor 183; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Grm7em2Mcwi glutamate receptor, metabotropic 7; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Gucy1a3em1Mcwi guanylate cyclase 1, soluble, alpha 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Hexim2em4Mcwi hexamethylene bis-acetamide inducible 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Hvcn1em1Mcwi hydrogen voltage-gated channel 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Hvcn1em2Mcwi hydrogen voltage-gated channel 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Il1r1em1Mcwi interleukin 1 receptor, type I; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Il1r1em2Mcwi interleukin 1 receptor, type I; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Il1r1em3Mcwi interleukin 1 receptor, type I; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Il2rgem2Mcwi interleukin 2 receptor, gamma; TALEN induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Itga9em1Mcwi integrin, alpha 9; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Kcnj11em5Mcwi potassium inwardly rectifying channel, subfamily J, member 11; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Kcnj11em9Mcwi potassium inwardly rectifying channel, subfamily J, member 11; zinc finger nuclease induced mutant 9, Medical College of Wisconsin Rattus norvegicus
Gene Kcnj16em1Mcwi potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Kcnmb1em1Mcwi potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Kcnmb1em3Mcwi potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Kcnq1em14Mcwi potassium voltage-gated channel, KQT-like subfamily, member 1; zinc finger nuclease induced mutant 14, Medical College of Wisconsin Rattus norvegicus
Gene Kcnq1em9Mcwi potassium voltage-gated channel, KQT-like subfamily, member 1; zinc finger nuclease induced mutant 9, Medical College of Wisconsin Rattus norvegicus
Gene Ldlrem1Mcwi low density lipoprotein receptor; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ldlrem2Mcwi low density lipoprotein receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Ldlrem3Mcwi low density lipoprotein receptor; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Ldlrem4Mcwi low density lipoprotein receptor; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Lepem5Mcwi leptin; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Lpin1em1Mcwi lipin 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Lssem2Mcwi lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Mas1em1Mcwi MAS1 oncogene; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Mir29b1em1Mcwi microRNA 29b-1; TALEN induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Mmp2em2Mcwi matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Msraem3Mcwi methionine sulfoxide reductase A; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Msraem4Mcwi methionine sulfoxide reductase A; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Mstnem1Mcwi myostatin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Mstnem2Mcwi myostatin; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Mstnem3Mcwi myostatin; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Mthfrem1Mcwi methylenetetrahydrofolate reductase (NAD(P)H); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Myadml2em1Mcwi myeloid-associated differentiation marker-like 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Myadml2em5Mcwi myeloid-associated differentiation marker-like 2; zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Mylipem1Mcwi myosin regulatory light chain interacting protein; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Mylipem2Mcwi myosin regulatory light chain interacting protein; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Mylipem3Mcwi myosin regulatory light chain interacting protein; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Nat8em4Mcwi N-acetyltransferase 8; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Ncf2em1Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ncf2em4Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Nckap5em1Mcwi NCK-associated protein 5; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Nckap5em2Mcwi NCK-associated protein 5; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Nckap5em3Mcwi NCK-associated protein 5; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Nckap5em4Mcwi NCK-associated protein 5; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Ndufc2em1Mcwi NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ndufc2em2Mcwi NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Nfe2l2em1Mcwi nuclear factor, erythroid 2-like 2; TALEN induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Nos3em13Mcwi nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 13, Medical College of Wisconsin Rattus norvegicus
Gene Nos3em2Mcwi nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Nos3em8Mcwi nitric oxide synthase 3, endothelial cell; zinc finger nuclease induced mutant 8, Medical College of Wisconsin Rattus norvegicus
Gene Nox4em1Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Nox4em2Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Nppaem4Mcwi natriuretic peptide precursor A; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Nppbem2Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Nppbem4Mcwi natriuretic peptide B; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Nr2f2em1Mcwi nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Pdcem2Mcwi phosducin; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Pdcem3Mcwi phosducin; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Plcd3em4Mcwi phospholipase C, delta 3; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Plcd3em7Mcwi phospholipase C, delta 3; zinc finger nuclease induced mutant 7, Medical College of Wisconsin Rattus norvegicus
Gene Plekha7em1Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Plod1em1Mcwi procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ppargem1Mcwi peroxisome proliferator-activated receptor gamma; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Prex1em2Mcwi phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Prokr1em1Mcwi prokineticin receptor 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Prokr1em2Mcwi prokineticin receptor 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Pruneem1Mcwi prune homolog (Drosophila); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Pruneem3Mcwi prune homolog (Drosophila); zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Ptpn11em1Mcwi protein tyrosine phosphatase, non-receptor type 11; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ptpn11em4Mcwi protein tyrosine phosphatase, non-receptor type 11; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Rab38em1Mcwi RAB38, member RAS oncogene family; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Rag1em1Mcwi recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Rag1em2Mcwi recombination activating gene 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Rasgrp3em1Mcwi RAS guanyl releasing protein 3 (calcium and DAG-regulated); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Rasgrp3em3Mcwi RAS guanyl releasing protein 3 (calcium and DAG-regulated); zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Renem1Mcwi renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Resp18em2Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Resp18em3Mcwi regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Strain SD-Fahem3Mcwi null Rattus norvegicus
Strain SD-Il2rgem2Mcwi null Rattus norvegicus
Strain SD-Nfe2l2em1Mcwi null Rattus norvegicus
Gene Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Sh2b3em2Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Strain SHR-Ndufc2em1Mcwi null Rattus norvegicus
Strain SHR-Ndufc2em2Mcwi null Rattus norvegicus
Gene Slc30a8em1Mcwi solute carrier family 30 (zinc transporter), member 8; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Slc30a8em2Mcwi solute carrier family 30 (zinc transporter), member 8; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Slc34a1em1Mcwi solute carrier family 34 (sodium phosphate), member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Slc6a12em1Mcwi solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Slc7a9em1Mcwi solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Slc7a9em2Mcwi solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Sorcs1em1Mcwi sortilin-related VPS10 domain containing receptor 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Sorcs2em1Mcwi sortilin-related VPS10 domain containing receptor 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Sorcs2em4Mcwi sortilin-related VPS10 domain containing receptor 2; zinc finger nuclease induced mutant 4, Medical College of Wisconsin Rattus norvegicus
Gene Sorcs3em1Mcwi sortilin-related VPS10 domain containing receptor 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Strain SS-Abcb1bem2Mcwi null Rattus norvegicus
Strain SS-Acad10em2Mcwi+/+ SS-Acad10em2Mcwi+/Acad10em2Mcwi+ Rattus norvegicus
Strain SS-Acad10em2Mcwi-/- SS-Acad10em2Mcwi-/Acad10em2Mcwi- Rattus norvegicus
Strain SS-Acad10em2Mcwi null Rattus norvegicus
Strain SS-Aceem1Mcwi null Rattus norvegicus
Strain SS-Aceem2Mcwi null Rattus norvegicus
Strain SS-Adipoqem1Mcwi null Rattus norvegicus
Strain SS-Adipoqem2Mcwi null Rattus norvegicus
Strain SS-Adora2bem1Mcwi null Rattus norvegicus
Strain SS-Adora2bem2Mcwi null Rattus norvegicus
Strain SS-Adra2aem1Mcwi+/+ SS-Adra2aem1Mcwi+/Adra2aem1Mcwi+ Rattus norvegicus
Strain SS-Adra2aem1Mcwi-/- SS-Adra2aem1Mcwi-/Adra2aem1Mcwi- Rattus norvegicus
Strain SS-Adra2aem1Mcwi null Rattus norvegicus
Strain SS-Agtr1aem1Mcwi+/+ SS-Agtr1aem1Mcwi+/Agtr1aem1Mcwi+ Rattus norvegicus
Strain SS-Agtr1aem1Mcwi-/- SS-Agtr1aem1Mcwi-/Agtr1aem1Mcwi- Rattus norvegicus
Strain SS-Agtr1aem1Mcwi null Rattus norvegicus
Strain SS-Agtr1aem5Mcwi-/- SS-Agtr1aem5Mcwi-/Agtr1aem5Mcwi- Rattus norvegicus
Strain SS-Agtr1aem5Mcwi null Rattus norvegicus
Strain SS-Agtrapem4Mcwi+/+ SS-Agtrapem4Mcwi+/Agtrapem4Mcwi+ Rattus norvegicus
Strain SS-Agtrapem4Mcwi-/- SS-Agtrapem4Mcwi-/Agtrapem4Mcwi- Rattus norvegicus
Strain SS-Agtrapem4Mcwi null Rattus norvegicus
Strain SS-Agtrapem8Mcwi+/+ SS-Agtrapem8Mcwi+/Agtrapem8Mcwi+ Rattus norvegicus
Strain SS-Agtrapem8Mcwi-/- SS-Agtrapem8Mcwi-/Agtrapem8Mcwi- Rattus norvegicus
Strain SS-Agtrapem8Mcwi null Rattus norvegicus
Strain SS-Aldh2em2Mcwi+/+ SS-Aldh2em2Mcwi+/Aldh2em2Mcwi+ Rattus norvegicus
Strain SS-Aldh2em2Mcwi-/- SS-Aldh2em2Mcwi-/Aldh2em2Mcwi- Rattus norvegicus
Strain SS-Aldh2em2Mcwi null Rattus norvegicus
Strain SS-Alms1em1Mcwi+/+ SS-Alms1em1Mcwi+/Alms1em1Mcwi+ Rattus norvegicus
Strain SS-Alms1em1Mcwi-/- SS-Alms1em1Mcwi-/Alms1em1Mcwi- Rattus norvegicus
Strain SS-Alms1em1Mcwi null Rattus norvegicus
Strain SS-Apoeem7Mcwi+/+ SS-Apoeem7Mcwi+/Apoeem7Mcwi+ Rattus norvegicus
Strain SS-Apoeem7Mcwi-/- SS-Apoeem7Mcwi-/Apoeem7Mcwi- Rattus norvegicus
Strain SS-Apoeem7Mcwi null Rattus norvegicus
Strain SS-Apoeem8Mcwi+/+ SS-Apoeem8Mcwi+/Apoeem8Mcwi+ Rattus norvegicus
Strain SS-Apoeem8Mcwi-/- SS-Apoeem8Mcwi-/Apoeem8Mcwi- Rattus norvegicus
Strain SS-Apoeem8Mcwi null Rattus norvegicus
Strain SS-Apoeem9Mcwi null Rattus norvegicus
Strain SS-Atp2b1em2Mcwi null Rattus norvegicus
Strain SS-Bcas3em4Mcwi+/+ SS-Bcas3em4Mcwi+/Bcas3em4Mcwi+ Rattus norvegicus
Strain SS-Bcas3em4Mcwi-/- SS-Bcas3em4Mcwi-/Bcas3em4Mcwi- Rattus norvegicus
Strain SS-Bcas3em4Mcwi null Rattus norvegicus
Strain SS-Bcat1em2Mcwi null Rattus norvegicus
Strain SS-Cacna1hem2Mcwi null Rattus norvegicus
Strain SS-Cd247em1Mcwi null Rattus norvegicus
Strain SS-Cd247em3Mcwi null Rattus norvegicus
Strain SS-Cd247em5Mcwi null Rattus norvegicus
Strain SS-Cdh13em1Mcwi+/+ SS-Cdh13em1Mcwi+/Cdh13em1Mcwi+ Rattus norvegicus
Strain SS-Cdh13em1Mcwi-/- SS-Cdh13em1Mcwi-/Cdh13em1Mcwi- Rattus norvegicus
Strain SS-Cdh13em1Mcwi null Rattus norvegicus
Strain SS-Clcn6em2Mcwi null Rattus norvegicus
Strain SS-Comtem1Mcwi null Rattus norvegicus
Strain SS-Cst3em1Mcwi null Rattus norvegicus
Strain SS-Cst3em3Mcwi null Rattus norvegicus
Strain SS-Cubnem1Mcwi null Rattus norvegicus
Strain SS-Cybaem1Mcwi+/+ SS-Cybaem1Mcwi+/Cybaem1Mcwi+ Rattus norvegicus
Strain SS-Cybaem1Mcwi-/- SS-Cybaem1Mcwi-/Cybaem1Mcwi- Rattus norvegicus
Strain SS-Cybaem1Mcwi null Rattus norvegicus
Strain SS-Cyp1a1em1Mcwi+/+ SS-Cyp1a1em1Mcwi+/Cyp1a1em1Mcwi+ Rattus norvegicus
Strain SS-Cyp1a1em1Mcwi-/- SS-Cyp1a1em1Mcwi-/Cyp1a1em1Mcwi- Rattus norvegicus
Strain SS-Cyp1a1em1Mcwi null Rattus norvegicus
Strain SS-Cyp1a1em2Mcwi+/+ SS-Cyp1a1em2Mcwi+/Cyp1a1em2Mcwi+ Rattus norvegicus
Strain SS-Cyp1a1em2Mcwi-/- SS-Cyp1a1em2Mcwi-/Cyp1a1em2Mcwi- Rattus norvegicus
Strain SS-Cyp1a1em2Mcwi null Rattus norvegicus
Strain SS-Cyp1a1em5Mcwi+/+ SS-Cyp1a1em5Mcwi+/Cyp1a1em5Mcwi+ Rattus norvegicus
Strain SS-Cyp1a1em5Mcwi-/- SS-Cyp1a1em5Mcwi-/Cyp1a1em5Mcwi- Rattus norvegicus
Strain SS-Cyp1a1em5Mcwi null Rattus norvegicus
Strain SS-Dguokem1Mcwi null Rattus norvegicus
Strain SS-Dguokem2Mcwi null Rattus norvegicus
Strain SS-Dguokem3Mcwi null Rattus norvegicus
Strain SS-Dguokem4Mcwi null Rattus norvegicus
Strain SS-Ets1em1Mcwi+/+ SS-Ets1em1Mcwi+/Ets1em1Mcwi+ Rattus norvegicus
Strain SS-Ets1em1Mcwi-/+ SS-Ets1em1Mcwi-/Ets1em1Mcwi+ Rattus norvegicus
Strain SS-Ets1em1Mcwi null Rattus norvegicus
Strain SS-Fgf1em2Mcwi null Rattus norvegicus
Strain SS-Fgf5em1Mcwi null Rattus norvegicus
Strain SS-Fgf5em5Mcwi null Rattus norvegicus
Strain SS-Fynem1Mcwi null Rattus norvegicus
Strain SS-Fynem6Mcwi null Rattus norvegicus
Strain SS-Gnb3em1Mcwi null Rattus norvegicus
Strain SS-Gpr183em1Mcwi+/+ SS-Gpr183em1Mcwi+/Gpr183em1Mcwi+ Rattus norvegicus
Strain SS-Gpr183em1Mcwi-/- SS-Gpr183em1Mcwi-/Gpr183em1Mcwi- Rattus norvegicus
Strain SS-Gpr183em1Mcwi null Rattus norvegicus
Strain SS-Gpr183em2Mcwi+/+ SS-Gpr183em2Mcwi+/Gpr183em2Mcwi+ Rattus norvegicus
Strain SS-Gpr183em2Mcwi-/- SS-Gpr183em2Mcwi-/Gpr183em2Mcwi- Rattus norvegicus
Strain SS-Gpr183em2Mcwi null Rattus norvegicus
Strain SS-Gpr183em3Mcwi+/+ SS-Gpr183em3Mcwi+/Gpr183em3Mcwi+ Rattus norvegicus
Strain SS-Gpr183em3Mcwi-/- SS-Gpr183em3Mcwi-/Gpr183em3Mcwi- Rattus norvegicus
Strain SS-Gpr183em3Mcwi null Rattus norvegicus
Strain SS-Grm7em2Mcwi null Rattus norvegicus
Strain SS-Gucy1a3em1Mcwi null Rattus norvegicus
Strain SS-Hexim2em4Mcwi+/+ SS-Hexim2em4Mcwi+/Hexim2em4Mcwi+ Rattus norvegicus
Strain SS-Hexim2em4Mcwi-/- SS-Hexim2em4Mcwi-/Hexim2em4Mcwi- Rattus norvegicus
Strain SS-Hexim2em4Mcwi null Rattus norvegicus
Strain SS-Hvcn1em1Mcwi null Rattus norvegicus
Strain SS-Hvcn1em2Mcwi-/- null Rattus norvegicus
Strain SS-Itga9em1Mcwi+/+ SS-Itga9em1Mcwi+/Itga9em1Mcwi+ Rattus norvegicus
Strain SS-Itga9em1Mcwi null Rattus norvegicus
Strain SS-Kcnj11em5Mcwi null Rattus norvegicus
Strain SS-Kcnj11em9Mcwi null Rattus norvegicus
Strain SS-Kcnj16em1Mcwi null Rattus norvegicus
Strain SS-Kcnmb1em1Mcwi null Rattus norvegicus
Strain SS-Kcnmb1em3Mcwi null Rattus norvegicus
Strain SS-Kcnq1em14Mcwi+/+ SS-Kcnq1em14Mcwi+/Kcnq1em14Mcwi+ Rattus norvegicus
Strain SS-Kcnq1em14Mcwi-/- SS-Kcnq1em14Mcwi-/Kcnq1em14Mcwi- Rattus norvegicus
Strain SS-Kcnq1em14Mcwi null Rattus norvegicus
Strain SS-Kcnq1em9Mcwi null Rattus norvegicus
Strain SS-Ldlrem1Mcwi null Rattus norvegicus
Strain SS-Ldlrem2Mcwi null Rattus norvegicus
Strain SS-Ldlrem3Mcwi null Rattus norvegicus
Strain SS-Ldlrem4Mcwi null Rattus norvegicus
Strain SS-Lepem5Mcwi null Rattus norvegicus
Strain SS-Leprem2Mcwi null Rattus norvegicus
Strain SS-Lpin1em1Mcwi null Rattus norvegicus
Strain SS-Lssem2Mcwi null Rattus norvegicus
Strain SS-Mas1em1Mcwi+/+ SS-Mas1em1Mcwi+/Mas1em1Mcwi+ Rattus norvegicus
Strain SS-Mas1em1Mcwi-/- SS-Mas1em1Mcwi-/Mas1em1Mcwi- Rattus norvegicus
Strain SS-Mas1em1Mcwi null Rattus norvegicus
Strain SS-Mmp2em2Mcwi null Rattus norvegicus
Strain SS-Msraem3Mcwi+/+ SS-Msraem3Mcwi+/Msraem3Mcwi+ Rattus norvegicus
Strain SS-Msraem3Mcwi-/- SS-Msraem3Mcwi-/Msraem3Mcwi- Rattus norvegicus
Strain SS-Msraem3Mcwi null Rattus norvegicus
Strain SS-Msraem4Mcwi+/+ SS-Msraem4Mcwi+/Msraem4Mcwi+ Rattus norvegicus
Strain SS-Msraem4Mcwi-/- SS-Msraem4Mcwi-/Msraem4Mcwi- Rattus norvegicus
Strain SS-Msraem4Mcwi null Rattus norvegicus
Strain SS-Mstnem1Mcwi+/+ SS-Mstnem1Mcwi+/Mstnem1Mcwi+ Rattus norvegicus
Strain SS-Mstnem1Mcwi-/- SS-Mstnem1Mcwi-/Mstnem1Mcwi- Rattus norvegicus
Strain SS-Mstnem1Mcwi null Rattus norvegicus
Strain SS-Mstnem2Mcwi null Rattus norvegicus
Strain SS-Mstnem3Mcwi+/+ SS-Mstnem3Mcwi+/Mstnem3Mcwi+ Rattus norvegicus
Strain SS-Mstnem3Mcwi-/+ SS-Mstnem3Mcwi-/Mstnem3Mcwi+ Rattus norvegicus
Strain SS-Mstnem3Mcwi-/- SS-Mstnem3Mcwi-/Mstnem3Mcwi- Rattus norvegicus
Strain SS-Mstnem3Mcwi null Rattus norvegicus
Strain SS-Mthfrem1Mcwi+/+ SS-Mthfrem1Mcwi+/Mthfrem1Mcwi+ Rattus norvegicus
Strain SS-Mthfrem1Mcwi-/+ SS-Mthfrem1Mcwi-/Mthfrem1Mcwi+ Rattus norvegicus
Strain SS-Mthfrem1Mcwi null Rattus norvegicus
Strain SS-Myadml2em1Mcwi null Rattus norvegicus
Strain SS-Myadml2em5Mcwi null Rattus norvegicus
Strain SS-Mylipem1Mcwi null Rattus norvegicus
Strain SS-Mylipem2Mcwi null Rattus norvegicus
Strain SS-Mylipem3Mcwi null Rattus norvegicus
Strain SS-Nat8em4Mcwi null Rattus norvegicus
Strain SS-Ncf2em1Mcwi+/+ SS-Ncf2em1Mcwi+/Ncf2em1Mcwi+ Rattus norvegicus
Strain SS-Ncf2em1Mcwi-/- SS-Ncf2em1Mcwi-/Ncf2em1Mcwi- Rattus norvegicus
Strain SS-Ncf2em1Mcwi null Rattus norvegicus
Strain SS-Ncf2em4Mcwi null Rattus norvegicus
Strain SS-Nckap5em1Mcwi+/+ SS-Nckap5em1Mcwi+/Nckap5em1Mcwi+ Rattus norvegicus
Strain SS-Nckap5em1Mcwi-/- SS-Nckap5em1Mcwi-/Nckap5em1Mcwi- Rattus norvegicus
Strain SS-Nckap5em1Mcwi null Rattus norvegicus
Strain SS-Nckap5em2Mcwi+/+ SS-Nckap5em2Mcwi+/Nckap5em2Mcwi+ Rattus norvegicus
Strain SS-Nckap5em2Mcwi-/- SS-Nckap5em2Mcwi-/Nckap5em2Mcwi- Rattus norvegicus
Strain SS-Nckap5em2Mcwi null Rattus norvegicus
Strain SS-Nckap5em3Mcwi+/+ SS-Nckap5em3Mcwi+/Nckap5em3Mcwi+ Rattus norvegicus
Strain SS-Nckap5em3Mcwi-/- SS-Nckap5em3Mcwi-/Nckap5em3Mcwi- Rattus norvegicus
Strain SS-Nckap5em3Mcwi null Rattus norvegicus
Strain SS-Nos3em13Mcwi null Rattus norvegicus
Strain SS-Nos3em2Mcwi null Rattus norvegicus
Strain SS-Nos3em8Mcwi null Rattus norvegicus
Strain SS-Nox4em1Mcwi null Rattus norvegicus
Strain SS-Nox4em2Ncf2em1Mcwi null Rattus norvegicus
Strain SS-Nox4em2Mcwi+/+ SS-Nox4em2Mcwi+/Nox4em2Mcwi+ Rattus norvegicus
Strain SS-Nox4em2Mcwi-/+ SS-Nox4em2Mcwi-/Nox4em2Mcwi+ Rattus norvegicus
Strain SS-Nox4em2Mcwi-/- SS-Nox4em2Mcwi-/Nox4em2Mcwi- Rattus norvegicus
Strain SS-Nox4em2Mcwi null Rattus norvegicus
Strain SS-Nppaem4Mcwi+/+ SS-Nppaem4Mcwi+/Nppaem4Mcwi+ Rattus norvegicus
Strain SS-Nppaem4Mcwi-/- SS-Nppaem4Mcwi-/Nppaem4Mcwi- Rattus norvegicus
Strain SS-Nppaem4Mcwi null Rattus norvegicus
Strain SS-Nppbem2Mcwi+/+ SS-Nppbem2Mcwi+/Nppbem2Mcwi+ Rattus norvegicus
Strain SS-Nppbem2Mcwi-/- SS-Nppbem2Mcwi-/Nppbem2Mcwi- Rattus norvegicus
Strain SS-Nppbem2Mcwi null Rattus norvegicus
Strain SS-Nppbem4Mcwi+/+ SS-Nppbem4Mcwi+/Nppbem4Mcwi+ Rattus norvegicus
Strain SS-Nppbem4Mcwi-/- SS-Nppbem4Mcwi-/Nppbem4Mcwi- Rattus norvegicus
Strain SS-Nppbem4Mcwi null Rattus norvegicus
Strain SS-Nr2f2em1Mcwi null Rattus norvegicus
Strain SS-Pdcem2Mcwi null Rattus norvegicus
Strain SS-Pdcem3Mcwi null Rattus norvegicus
Strain SS-Plcd3em4Mcwi+/+ SS-Plcd3em4Mcwi+/Plcd3em4Mcwi+ Rattus norvegicus
Strain SS-Plcd3em4Mcwi-/- SS-Plcd3em4Mcwi-/Plcd3em4Mcwi- Rattus norvegicus
Strain SS-Plcd3em4Mcwi null Rattus norvegicus
Strain SS-Plcd3em7Mcwi+/+ SS-Plcd3em7Mcwi+/Plcd3em7Mcwi+ Rattus norvegicus
Strain SS-Plcd3em7Mcwi-/- SS-Plcd3em7Mcwi-/Plcd3em7Mcwi- Rattus norvegicus
Strain SS-Plcd3em7Mcwi null Rattus norvegicus
Strain SS-Plekha7em1Mcwi+/+ SS-Plekha7em1Mcwi+/Plekha7em1Mcwi+ Rattus norvegicus
Strain SS-Plekha7em1Mcwi-/- SS-Plekha7em1Mcwi-/Plekha7em1Mcwi- Rattus norvegicus
Strain SS-Plekha7em1Mcwi null Rattus norvegicus
Strain SS-Plekha7em4Mcwi+/+ SS-Plekha7em4Mcwi+/Plekha7em4Mcwi+ Rattus norvegicus
Strain SS-Plekha7em4Mcwi-/- SS-Plekha7em4Mcwi-/Plekha7em4Mcwi- Rattus norvegicus
Strain SS-Plekha7em4Mcwi null Rattus norvegicus
Strain SS-Plod1em1Mcwi+/+ SS-Plod1em1Mcwi+/Plod1em1Mcwi+ Rattus norvegicus
Strain SS-Plod1em1Mcwi-/- SS-Plod1em1Mcwi-/Plod1em1Mcwi- Rattus norvegicus
Strain SS-Plod1em1Mcwi null Rattus norvegicus
Strain SS-Ppargem1Mcwi null Rattus norvegicus
Strain SS-Prex1em2Mcwi-/- SS-Prex1em2Mcwi-/Prex1em2Mcwi- Rattus norvegicus
Strain SS-Prex1em2Mcwi null Rattus norvegicus
Strain SS-Prokr1em1Mcwi+/+ SS-Prokr1em1Mcwi+/Prokr1em1Mcwi+ Rattus norvegicus
Strain SS-Prokr1em1Mcwi-/- SS-Prokr1em1Mcwi-/Prokr1em1Mcwi- Rattus norvegicus
Strain SS-Prokr1em1Mcwi null Rattus norvegicus
Strain SS-Prokr1em2Mcwi+/+ SS-Prokr1em2Mcwi+/Prokr1em2Mcwi+ Rattus norvegicus
Strain SS-Prokr1em2Mcwi-/- SS-Prokr1em2Mcwi-/Prokr1em2Mcwi- Rattus norvegicus
Strain SS-Prokr1em2Mcwi null Rattus norvegicus
Strain SS-Pruneem1Mcwi null Rattus norvegicus
Strain SS-Pruneem3Mcwi null Rattus norvegicus
Strain SS-Ptpn11em1Mcwi null Rattus norvegicus
Strain SS-Ptpn11em4Mcwi null Rattus norvegicus
Strain SS-Rag1em1Mcwi+/+ SS-Rag1em1Mcwi+/Rag1em1Mcwi+ Rattus norvegicus
Strain SS-Rag1em1Mcwi-/- SS-Rag1em1Mcwi-/Rag1em1Mcwi- Rattus norvegicus
Strain SS-Rag1em1Mcwi null Rattus norvegicus
Strain SS-Rag1em2Mcwi+/+ SS-Rag1em2Mcwi+/Rag1em2Mcwi+ Rattus norvegicus
Strain SS-Rag1em2Mcwi-/- SS-Rag1em2Mcwi-/Rag1em2Mcwi- Rattus norvegicus
Strain SS-Rag1em2Mcwi null Rattus norvegicus
Strain SS-Rasgrp3em1Mcwi+/+ SS-Rasgrp3em1Mcwi+/Rasgrp3em1Mcwi+ Rattus norvegicus
Strain SS-Rasgrp3em1Mcwi-/- SS-Rasgrp3em1Mcwi-/Rasgrp3em1Mcwi- Rattus norvegicus
Strain SS-Rasgrp3em1Mcwi null Rattus norvegicus
Strain SS-Rasgrp3em3Mcwi null Rattus norvegicus
Strain SS-Renem1Mcwi+/+ SS-Renem1Mcwi+/Renem1Mcwi+ Rattus norvegicus
Strain SS-Renem1Mcwi-/- SS-Renem1Mcwi-/Renem1Mcwi- Rattus norvegicus
Strain SS-Renem1Mcwi null Rattus norvegicus
Strain SS-Resp18em2Mcwi null Rattus norvegicus
Strain SS-Resp18em3Mcwi null Rattus norvegicus
Strain SS-Sh2b3em1Mcwi+/+ SS-Sh2b3em1Mcwi+/Sh2b3em1Mcwi+ Rattus norvegicus
Strain SS-Sh2b3em1Mcwi-/+ SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+ Rattus norvegicus
Strain SS-Sh2b3em1Mcwi-/- SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi- Rattus norvegicus
Strain SS-Sh2b3em1Mcwi null Rattus norvegicus
Strain SS-Sh2b3em2Mcwi-/- SS-Sh2b3em2Mcwi-/Sh2b3em2Mcwi- Rattus norvegicus
Strain SS-Sh2b3em2Mcwi null Rattus norvegicus
Strain SS-Slc30a8em1Mcwi+/+ SS-Slc30a8em1Mcwi+/Slc30a8em1Mcwi+ Rattus norvegicus
Strain SS-Slc30a8em1Mcwi-/- SS-Slc30a8em1Mcwi-/Slc30a8em1Mcwi- Rattus norvegicus
Strain SS-Slc30a8em1Mcwi null Rattus norvegicus
Strain SS-Slc30a8em2Mcwi+/+ SS-Slc30a8em2Mcwi+/Slc30a8em2Mcwi+ Rattus norvegicus
Strain SS-Slc30a8em2Mcwi-/- SS-Slc30a8em2Mcwi-/Slc30a8em2Mcwi- Rattus norvegicus
Strain SS-Slc30a8em2Mcwi null Rattus norvegicus
Strain SS-Slc34a1em1Mcwi null Rattus norvegicus
Strain SS-Slc6a12em1Mcwi null Rattus norvegicus
Strain SS-Slc7a9em1Mcwi null Rattus norvegicus
Strain SS-Slc7a9em2Mcwi null Rattus norvegicus
Strain SS-Sorcs2em1Mcwi null Rattus norvegicus
Strain SS-Sorcs2em4Mcwi null Rattus norvegicus
Strain SS-Stc1em2Mcwi null Rattus norvegicus
Strain SS-Stk39em2Mcwi+/+ SS-Stk39em2Mcwi+/Stk39em2Mcwi+ Rattus norvegicus
Strain SS-Stk39em2Mcwi-/+ SS-Stk39em2Mcwi-/Stk39em2Mcwi+ Rattus norvegicus
Strain SS-Stk39em2Mcwi-/- SS-Stk39em2Mcwi-/Stk39em2Mcwi- Rattus norvegicus
Strain SS-Stk39em2Mcwi null Rattus norvegicus
Strain SS-Tcf7l2em1Mcwi+/+ SS-Tcf7l2em1Mcwi+/Tcf7l2em1Mcwi+ Rattus norvegicus
Strain SS-Tcf7l2em1Mcwi-/+ SS-Tcf7l2em1Mcwi-/Tcf7l2em1Mcwi+ Rattus norvegicus
Strain SS-Tcf7l2em1Mcwi-/- SS-Tcf7l2em1Mcwi-/Tcf7l2em1Mcwi- Rattus norvegicus
Strain SS-Tcf7l2em1Mcwi null Rattus norvegicus
Strain SS-Tfdp2em2Mcwi+/+ SS-Tfdp2em2Mcwi+/Tfdp2em2Mcwi+ Rattus norvegicus
Strain SS-Tfdp2em2Mcwi-/- SS-Tfdp2em2Mcwi-/Tfdp2em2Mcwi- Rattus norvegicus
Strain SS-Tfdp2em2Mcwi null Rattus norvegicus
Strain SS-Tfdp2em5Mcwi null Rattus norvegicus
Strain SS-Tfdp2em6Mcwi null Rattus norvegicus
Strain SS-Tgfb1em1Mcwi+/+ SS-Tgfb1em1Mcwi+/Tgfb1em1Mcwi+ Rattus norvegicus
Strain SS-Tgfb1em1Mcwi null Rattus norvegicus
Strain SS-Tgfb1em3Mcwi+/- SS-Tgfb1em3Mcwi+/Tgfb1em3Mcwi- Rattus norvegicus
Strain SS-Tgfb1em3Mcwi null Rattus norvegicus
Strain SS-Trafd1em1Mcwi null Rattus norvegicus
Strain SS-Ube2q2em3Mcwi+/+ SS-Ube2q2em3Mcwi+/Ube2q2em3Mcwi+ Rattus norvegicus
Strain SS-Ube2q2em3Mcwi-/- SS-Ube2q2em3Mcwi-/Ube2q2em3Mcwi- Rattus norvegicus
Strain SS-Ube2q2em3Mcwi null Rattus norvegicus
Strain SS-Ulk3em1Mcwi+/+ SS-Ulk3em1Mcwi+/Ulk3em1Mcwi+ Rattus norvegicus
Strain SS-Ulk3em1Mcwi-/+ SS-Ulk3em1Mcwi-/Ulk3em1Mcwi+ Rattus norvegicus
Strain SS-Ulk3em1Mcwi-/- SS-Ulk3em1Mcwi-/Ulk3em1Mcwi- Rattus norvegicus
Strain SS-Ulk3em1Mcwi null Rattus norvegicus
Strain SS-Ulk3em4Mcwi+/+ SS-Ulk3em4Mcwi+/Ulk3em4Mcwi+ Rattus norvegicus
Strain SS-Ulk3em4Mcwi-/+ SS-Ulk3em4Mcwi-/Ulk3em4Mcwi+ Rattus norvegicus
Strain SS-Ulk3em4Mcwi-/- SS-Ulk3em4Mcwi-/Ulk3em4Mcwi- Rattus norvegicus
Strain SS-Ulk3em4Mcwi null Rattus norvegicus
Strain SS-Ulk4em3Mcwi-/- SS-Ulk4em3Mcwi-/Ulk4em3Mcwi- Rattus norvegicus
Strain SS-Ulk4em3Mcwi null Rattus norvegicus
Strain SS-Umodem1Mcwi null Rattus norvegicus
Strain SS-Wdr72em1Mcwi+/+ SS-Wdr72em1Mcwi+/Wdr72em1Mcwi+ Rattus norvegicus
Strain SS-Wdr72em1Mcwi-/- SS-Wdr72em1Mcwi-/Wdr72em1Mcwi- Rattus norvegicus
Strain SS-Wdr72em1Mcwi null Rattus norvegicus
Strain SS-Wdr72em2Mcwi+/+ SS-Wdr72em2Mcwi+/Wdr72em2Mcwi+ Rattus norvegicus
Strain SS-Wdr72em2Mcwi-/- SS-Wdr72em2Mcwi-/Wdr72em2Mcwi- Rattus norvegicus
Strain SS-Wdr72em2Mcwi null Rattus norvegicus
Strain SS-Chr 13BN-Mir29bem1Mcwi null Rattus norvegicus
Strain SS-Chr 5BN-Cyp4a2em1Mcwi+/+ SS-Chr 5BN-Cyp4a2em1Mcwi+/Cyp4a2em1Mcwi+ Rattus norvegicus
Strain SS-Chr 5BN-Cyp4a2em1Mcwi-/+ SS-Chr 5BN-Cyp4a2em1Mcwi-/Cyp4a2em1Mcwi+ Rattus norvegicus
Strain SS-Chr 5BN-Cyp4a2em1Mcwi-/- SS-Chr 5BN-Cyp4a2em1Mcwi-/Cyp4a2em1Mcwi- Rattus norvegicus
Strain SS-Chr 5BN-Cyp4a2em1Mcwi null Rattus norvegicus
Strain SS-Chr 5BN-Cyp4a3em3Mcwi null Rattus norvegicus
Strain SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+ SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/Nckap5em4Mcwi+ Rattus norvegicus
Strain SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/+ SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/Nckap5em4Mcwi+ Rattus norvegicus
Strain SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/- SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/Nckap5em4Mcwi- Rattus norvegicus
Strain SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi null Rattus norvegicus
Gene Stc1em2Mcwi stanniocalcin 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Stk39em2Mcwi serine threonine kinase 39; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Tcf7l2em1Mcwi transcription factor 7-like 2 (T-cell specific, HMG-box); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Tfdp2em2Mcwi transcription factor Dp-2 (E2F dimerization partner 2); zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Tfdp2em5Mcwi transcription factor Dp-2 (E2F dimerization partner 2); zinc finger nuclease induced mutant 5, Medical College of Wisconsin Rattus norvegicus
Gene Tfdp2em6Mcwi transcription factor Dp-2 (E2F dimerization partner 2); zinc finger nuclease induced mutant 6, Medical College of Wisconsin Rattus norvegicus
Gene Tgfb1em1Mcwi transforming growth factor, beta 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Tgfb1em3Mcwi transforming growth factor, beta 1; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Tph2em2Mcwi tryptophan hydroxylase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus
Gene Tph2em3Mcwi tryptophan hydroxylase 2; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Trafd1em1Mcwi TRAF type zinc finger domain containing 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ube2q2em3Mcwi ubiquitin-conjugating enzyme E2Q family member 2; zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Ulk3em1Mcwi unc-51-like kinase 3 (C. elegans); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ulk3em4Mcwi unc-51-like kinase 3 (C. elegans); zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Ulk4em3Mcwi unc-51-like kinase 4 (C. elegans); zinc finger nuclease induced mutant 3, Medical College of Wisconsin Rattus norvegicus
Gene Umodem1Mcwi uromodulin zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Wdr72em1Mcwi WD repeat domain 72; zinc finger nuclease induced mutant 1, Medical College of Wisconsin Rattus norvegicus
Gene Wdr72em2Mcwi WD repeat domain 72; zinc finger nuclease induced mutant 2, Medical College of Wisconsin Rattus norvegicus

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