(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 mRNA] CTD PMID:31150632 (S)-naringenin increases expression ISO PON1 (Homo sapiens) 6480464 naringenin results in increased expression of PON1 mRNA CTD PMID:15169886 (S)-nicotine decreases activity ISO PON1 (Homo sapiens) 6480464 Nicotine results in decreased activity of PON1 protein CTD PMID:24478552 (S)-nicotine multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP affects the susceptibility to [Pesticides co-treated with Nicotine] CTD PMID:29747151 1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) increases activity ISO PON1 (Homo sapiens) 6480464 1 and 2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 1-naphthyl isothiocyanate multiple interactions ISO PON1 (Homo sapiens) 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of PON1 mRNA CTD PMID:27344345 17alpha-ethynylestradiol multiple interactions ISO Pon1 (Mus musculus) 6480464 [Ethinyl Estradiol co-treated with Desogestrel] affects the activity of PON1 protein more ... CTD PMID:17541152 and PMID:17942748 17beta-estradiol decreases expression ISO PON1 (Homo sapiens) 6480464 Estradiol results in decreased expression of PON1 mRNA CTD PMID:20106945 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of PON1 protein CTD PMID:32145629 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Plant Preparations] results in decreased expression of PON1 mRNA CTD PMID:26945725 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Pon1 (Mus musculus) 6480464 [2 more ... CTD PMID:23457121 2,2',4,4',5,5'-hexachlorobiphenyl decreases activity EXP 6480464 2 more ... CTD PMID:26006071 2,2',5,5'-tetrachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:23829299 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO PON1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of PON1 mRNA CTD PMID:26434531 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO PON1 (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PON1 mRNA CTD PMID:26159488 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO PON1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of PON1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PON1 mRNA CTD PMID:16960034 and PMID:19692669 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Pon1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PON1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO PON1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PON1 mRNA CTD PMID:20106945 2,4,6-tribromophenol decreases expression ISO PON1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of PON1 mRNA CTD PMID:21346803 2,6-di-tert-butyl-4-methylphenol multiple interactions ISO PON1 (Homo sapiens) 6480464 Butylated Hydroxytoluene inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein] CTD PMID:16052486 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO PON1 (Homo sapiens) 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO PON1 (Homo sapiens) 6480464 farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] and farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 and PMID:15690306 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Pon1 (Mus musculus) 6480464 [3 more ... CTD PMID:23457121 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 401794573 3 more ... RGD 3,3',4,4',5-pentachlorobiphenyl increases activity EXP 6480464 3 more ... CTD PMID:25530946 and PMID:26006071 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO Pon1 (Mus musculus) 6480464 3 more ... CTD PMID:22653878 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:23644946 and PMID:34256052 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:19692669 more ... 3,4-dihydrocoumarin affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 SNP affects the metabolism of 3 and 4-dihydrocoumarin CTD PMID:25027835 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PON1 mRNA CTD PMID:30071829 3-methylcholanthrene increases activity EXP 6480464 Methylcholanthrene results in increased activity of PON1 protein CTD PMID:26006071 3-methylcholanthrene increases expression ISO PON1 (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of PON1 mRNA CTD PMID:15169886 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of PON1 protein CTD PMID:11551529 3-methylcholanthrene increases activity ISO PON1 (Homo sapiens) 6480464 Methylcholanthrene results in increased activity of PON1 protein CTD PMID:15169886 3-methylcholanthrene multiple interactions ISO PON1 (Homo sapiens) 6480464 7-ketocholesterol inhibits the reaction [Methylcholanthrene results in increased expression of PON1 mRNA] CTD PMID:15169886 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of PON1 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol decreases expression ISO PON1 (Homo sapiens) 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of PON1 mRNA CTD PMID:30616060 4-hydroxy-TEMPO multiple interactions EXP 6480464 tempol inhibits the reaction [LEP protein results in decreased activity of PON1 protein] CTD PMID:15829432 4-hydroxynon-2-enal multiple interactions ISO PON1 (Homo sapiens) 6480464 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] and 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:15375178 4-hydroxynon-2-enal decreases activity ISO PON1 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in decreased activity of PON1 protein CTD PMID:15375178 4-hydroxyphenyl retinamide increases expression ISO Pon1 (Mus musculus) 6480464 Fenretinide results in increased expression of PON1 mRNA CTD PMID:28973697 4-nitrophenol increases chemical synthesis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased chemical synthesis of 4-nitrophenol CTD PMID:16175651 4-nitrophenyl acetate increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of 4-nitrophenyl acetate CTD PMID:21382471 6-propyl-2-thiouracil multiple interactions EXP 6480464 Vitamin E inhibits the reaction [Propylthiouracil results in decreased activity of PON1 protein] CTD PMID:15386442 6-propyl-2-thiouracil decreases activity EXP 6480464 Propylthiouracil results in decreased activity of PON1 protein CTD PMID:15386442 7,9-dihydro-1H-purine-2,6,8(3H)-trione affects abundance ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism affects the abundance of Uric Acid CTD PMID:23747713 7-ketocholesterol multiple interactions ISO PON1 (Homo sapiens) 6480464 7-ketocholesterol inhibits the reaction [Methylcholanthrene results in increased expression of PON1 mRNA] more ... CTD PMID:15169886 and PMID:15458977 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of PON1 mRNA CTD PMID:31881176 acetylsalicylic acid increases expression ISO PON1 (Homo sapiens) 6480464 Aspirin results in increased expression of PON1 mRNA CTD PMID:18519978 acetylsalicylic acid increases expression ISO Pon1 (Mus musculus) 6480464 Aspirin results in increased expression of PON1 mRNA CTD PMID:18519978 acetylsalicylic acid increases activity EXP 6480464 Aspirin results in increased activity of PON1 mRNA and Aspirin results in increased activity of PON1 protein CTD PMID:18519978 acetylsalicylic acid multiple interactions ISO Pon1 (Mus musculus) 6480464 AHR mutant form inhibits the reaction [Aspirin results in increased activity of PON1 protein] and AHR mutant form inhibits the reaction [Aspirin results in increased expression of PON1 mRNA] CTD PMID:18519978 acetylsalicylic acid increases activity ISO PON1 (Homo sapiens) 6480464 Aspirin results in increased activity of PON1 protein CTD PMID:18519978 acrolein multiple interactions ISO PON1 (Homo sapiens) 6480464 [PON1 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]] which results in increased chemical synthesis of 5 more ... CTD PMID:20353174 aflatoxin B1 affects expression ISO PON1 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of PON1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO PON1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PON1 mRNA CTD PMID:27153756 aflatoxin B1 decreases methylation ISO PON1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PON1 gene CTD PMID:27153756 albuterol decreases activity ISO PON1 (Homo sapiens) 6480464 Albuterol results in decreased activity of PON1 protein CTD PMID:31581362 aldicarb multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb and [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb CTD PMID:27132127 aldicarb multiple interactions EXP 6480464 [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb and [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb CTD PMID:27132127 alendronic acid decreases activity EXP 6480464 Alendronate results in decreased activity of PON1 protein CTD PMID:27387541 alendronic acid multiple interactions EXP 6480464 [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone more ... CTD PMID:27387541 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PON1 mRNA CTD PMID:16483693 ampicillin decreases activity ISO Pon1 (Mus musculus) 6480464 Ampicillin results in decreased activity of PON1 protein CTD PMID:16880604 ampicillin decreases activity ISO PON1 (Homo sapiens) 6480464 Ampicillin results in decreased activity of PON1 protein CTD PMID:16880604 and PMID:31581362 angelica lactone decreases activity ISO PON1 (Homo sapiens) 6480464 angelica lactone results in decreased activity of PON1 protein CTD PMID:31209508 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO PON1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Chenodeoxycholic Acid results in decreased expression of PON1 mRNA] more ... CTD PMID:16269825 arachidonic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] and Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:15375178 arachidonic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Arachidonic Acid results in decreased activity of PON1 protein CTD PMID:15375178 arsane affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP affects the susceptibility to Arsenic and PON1 protein affects the susceptibility to Arsenic CTD PMID:19152805 and PMID:19371607 arsenic atom affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP affects the susceptibility to Arsenic and PON1 protein affects the susceptibility to Arsenic CTD PMID:19152805 and PMID:19371607 atazanavir sulfate decreases activity EXP 6480464 Atazanavir Sulfate results in decreased activity of PON1 protein CTD PMID:27378623 atorvastatin calcium multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the reaction [Atorvastatin results in increased abundance of Cholesterol more ... CTD PMID:16238680 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein] CTD PMID:30273964 atorvastatin calcium increases expression ISO PON1 (Homo sapiens) 6480464 Atorvastatin results in increased expression of PON1 mRNA CTD PMID:15690306 atorvastatin calcium increases activity ISO PON1 (Homo sapiens) 6480464 Atorvastatin results in increased activity of PON1 protein CTD PMID:15324535 and PMID:15969877 benzo[a]pyrene decreases expression ISO PON1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PON1 mRNA CTD PMID:20106945 and PMID:32234424 benzo[a]pyrene affects methylation ISO PON1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PON1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO PON1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of PON1 mRNA CTD PMID:15169886 Benzo[k]fluoranthene increases expression ISO Pon1 (Mus musculus) 6480464 benzo(k)fluoranthene results in increased expression of PON1 mRNA CTD PMID:26377693 bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of PON1 mRNA CTD PMID:16648578 bifenthrin increases expression ISO Pon1 (Mus musculus) 6480464 bifenthrin results in increased expression of PON1 mRNA CTD PMID:26071804 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PON1 mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PON1 protein CTD PMID:32145629 bisphenol A increases expression ISO Pon1 (Mus musculus) 6480464 bisphenol A results in increased expression of PON1 mRNA CTD PMID:30245210 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PON1 mRNA CTD PMID:30903817 bosentan decreases expression ISO PON1 (Homo sapiens) 6480464 Bosentan results in decreased expression of PON1 mRNA CTD PMID:29761207 cadmium atom decreases activity EXP 6480464 Cadmium results in decreased activity of PON1 protein CTD PMID:22995158 cadmium atom affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Cadmium CTD PMID:23896426 cadmium atom increases activity EXP 6480464 Cadmium results in increased activity of PON1 protein CTD PMID:21787725 calcium atom increases activity EXP 6480464 Calcium results in increased activity of PON1 protein CTD PMID:27132127 calcium atom multiple interactions EXP 6480464 [Calcium results in increased activity of PON1 protein] which affects the susceptibility to O more ... CTD PMID:27132127 calcium atom increases activity ISO PON1 (Homo sapiens) 6480464 Calcium results in increased activity of PON1 protein CTD PMID:27132127 calcium atom multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium co-treated with 1 more ... CTD PMID:12871208 and PMID:27132127 calcium dichloride multiple interactions ISO PON1 (Homo sapiens) 6480464 Calcium Chloride promotes the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:16052486 calcium(0) multiple interactions EXP 6480464 [Calcium results in increased activity of PON1 protein] which affects the susceptibility to O more ... CTD PMID:27132127 calcium(0) increases activity EXP 6480464 Calcium results in increased activity of PON1 protein CTD PMID:27132127 calcium(0) multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium co-treated with 1 more ... CTD PMID:12871208 and PMID:27132127 calcium(0) increases activity ISO PON1 (Homo sapiens) 6480464 Calcium results in increased activity of PON1 protein CTD PMID:27132127 carbamazepine decreases activity ISO PON1 (Homo sapiens) 6480464 Carbamazepine results in decreased activity of PON1 protein CTD PMID:28032682 carbon nanotube decreases expression ISO Pon1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:27106021 chenodeoxycholic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Chenodeoxycholic Acid results in decreased expression of PON1 mRNA] CTD PMID:16269825 chenodeoxycholic acid decreases expression ISO PON1 (Homo sapiens) 6480464 Chenodeoxycholic Acid results in decreased expression of PON1 mRNA CTD PMID:16269825 chlorpyrifos increases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism results in increased susceptibility to Chlorpyrifos and PON1 protein results in increased susceptibility to Chlorpyrifos CTD PMID:16007003 and PMID:20176005 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of PON1 mRNA and Chlorpyrifos results in decreased expression of PON1 protein CTD PMID:31400774 chlorpyrifos multiple interactions EXP 6480464 [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA more ... CTD PMID:31400774 chlorpyrifos affects response to substance ISO Pon1 (Mus musculus) 6480464 PON1 protein affects the susceptibility to Chlorpyrifos CTD PMID:32976529 chlorpyrifos multiple interactions ISO Pon1 (Mus musculus) 6480464 [APOE protein results in increased susceptibility to Chlorpyrifos] which results in decreased expression of PON1 mRNA CTD PMID:29404631 chlorpyrifos decreases expression ISO Pon1 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of PON1 mRNA CTD PMID:29404631 chlorpyrifos increases response to substance ISO Pon1 (Mus musculus) 6480464 PON1 gene mutant form results in increased susceptibility to Chlorpyrifos CTD PMID:11022865 chlorpyrifos increases expression ISO Pon1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of PON1 mRNA CTD PMID:32715474 chlorpyrifos multiple interactions ISO PON1 (Homo sapiens) 6480464 Chlorpyrifos affects the expression of and results in increased activity of PON1 protein and PON1 protein polymorphism inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein] CTD PMID:26948828 and PMID:31981688 chlorpyrifos affects expression ISO PON1 (Homo sapiens) 6480464 Chlorpyrifos affects the expression of PON1 mRNA CTD PMID:26948828 chlorpyrifos affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the susceptibility to Chlorpyrifos and PON1 protein polymorphism affects the susceptibility to Chlorpyrifos CTD PMID:19907334 and PMID:31981688 chlorpyrifos increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Chlorpyrifos CTD PMID:16331452 chlorpyrifos affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of Chlorpyrifos CTD PMID:16002382 cholesterol increases export ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased export of Cholesterol CTD PMID:16229851 and PMID:16331452 cholesterol multiple interactions EXP 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein more ... CTD PMID:30273964 cholesterol decreases chemical synthesis ISO Pon1 (Mus musculus) 6480464 PON1 protein results in decreased chemical synthesis of Cholesterol CTD PMID:12615663 cholesterol decreases activity ISO Pon1 (Mus musculus) 6480464 Cholesterol results in decreased activity of PON1 protein CTD PMID:16115471 cholesterol decreases chemical synthesis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in decreased chemical synthesis of Cholesterol CTD PMID:12615663 cholic acid decreases expression ISO Pon1 (Mus musculus) 6480464 Cholic Acid results in decreased expression of PON1 mRNA and Cholic Acid results in decreased expression of PON1 protein CTD PMID:16269825 cholic acid multiple interactions EXP 6480464 [Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein more ... CTD PMID:30273964 chromium(3+) trichloride increases expression ISO Pon1 (Mus musculus) 6480464 chromic chloride results in increased expression of PON1 mRNA CTD PMID:12128095 ciprofibrate decreases expression ISO Pon1 (Mus musculus) 6480464 ciprofibrate results in decreased expression of PON1 mRNA CTD PMID:22653878 ciprofloxacin decreases activity ISO PON1 (Homo sapiens) 6480464 Ciprofloxacin results in decreased activity of PON1 protein CTD PMID:16880604 and PMID:31581362 ciprofloxacin decreases activity ISO Pon1 (Mus musculus) 6480464 Ciprofloxacin results in decreased activity of PON1 protein CTD PMID:16880604 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PON1 protein CTD PMID:22023808 clindamycin phosphate decreases activity ISO PON1 (Homo sapiens) 6480464 clindamycin phosphate results in decreased activity of PON1 protein CTD PMID:16880604 clindamycin phosphate decreases activity ISO Pon1 (Mus musculus) 6480464 clindamycin phosphate results in decreased activity of PON1 protein CTD PMID:16880604 clodronic acid multiple interactions EXP 6480464 [Clodronic Acid results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone more ... CTD PMID:27387541 clodronic acid decreases activity EXP 6480464 Clodronic Acid results in decreased activity of PON1 protein CTD PMID:27387541 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of PON1 protein CTD PMID:16470657 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of PON1 mRNA CTD PMID:15033592 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PON1 mRNA CTD PMID:17602206 clofibric acid decreases expression ISO Pon1 (Mus musculus) 6480464 Clofibric Acid results in decreased expression of PON1 mRNA CTD PMID:22653878 clopidogrel affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the susceptibility to clopidogrel CTD PMID:21170047 clopidogrel multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased metabolism of and results in increased activity of clopidogrel CTD PMID:21170047 cobalt atom decreases expression ISO Pon1 (Mus musculus) 6480464 Cobalt results in decreased expression of PON1 mRNA CTD PMID:34468815 copper atom decreases activity ISO PON1 (Homo sapiens) 6480464 Copper results in decreased activity of PON1 protein CTD PMID:16112460 copper atom affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Copper CTD PMID:23896426 copper atom multiple interactions ISO PON1 (Homo sapiens) 6480464 1 more ... CTD PMID:15104111 copper(0) decreases activity ISO PON1 (Homo sapiens) 6480464 Copper results in decreased activity of PON1 protein CTD PMID:16112460 copper(0) affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Copper CTD PMID:23896426 copper(0) multiple interactions ISO PON1 (Homo sapiens) 6480464 1 more ... CTD PMID:15104111 copper(II) sulfate multiple interactions ISO PON1 (Homo sapiens) 6480464 1 more ... CTD PMID:12871208 and PMID:15375178 copper(II) sulfate decreases expression ISO PON1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PON1 mRNA CTD PMID:19549813 coumarins increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Coumarins CTD PMID:20353174 cyclophosphamide increases activity EXP 6480464 Cyclophosphamide results in increased activity of PON1 protein CTD PMID:17874068 cyclosporin A decreases expression ISO PON1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PON1 mRNA CTD PMID:20106945 and PMID:27989131 desogestrel multiple interactions ISO Pon1 (Mus musculus) 6480464 [Ethinyl Estradiol co-treated with Desogestrel] affects the activity of PON1 protein CTD PMID:17541152 dexamethasone increases expression ISO PON1 (Homo sapiens) 6480464 Dexamethasone results in increased expression of PON1 mRNA and Dexamethasone results in increased expression of PON1 protein CTD PMID:26434531 Diallyl sulfide decreases expression ISO Pon1 (Mus musculus) 6480464 allyl sulfide results in decreased expression of PON1 mRNA CTD PMID:22653878 diazinon affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the susceptibility to Diazinon more ... CTD PMID:11888590 more ... diazinon multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism inhibits the reaction [Diazinon results in decreased activity of ACHE protein] CTD PMID:31981688 diazinon decreases expression EXP 6480464 Diazinon results in decreased expression of PON1 mRNA CTD PMID:29383019 diazinon increases response to substance ISO Pon1 (Mus musculus) 6480464 PON1 gene mutant form results in increased susceptibility to Diazinon CTD PMID:11022865 diazinon increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Diazinon CTD PMID:16331452 diazinon affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of Diazinon CTD PMID:16002382 and PMID:16027737 diazoxon decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism results in decreased susceptibility to diazoxon and PON1 protein results in decreased susceptibility to diazoxon CTD PMID:19071155 more ... diazoxon increases response to substance ISO Pon1 (Mus musculus) 6480464 PON1 gene mutant form results in increased susceptibility to diazoxon CTD PMID:11022865 diazoxon multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism affects the reaction [PON1 protein results in increased hydrolysis of diazoxon] CTD PMID:19446239 diazoxon increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein polymorphism results in increased hydrolysis of diazoxon and PON1 protein results in increased hydrolysis of diazoxon CTD PMID:10898114 more ... diazoxon decreases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism results in decreased hydrolysis of diazoxon CTD PMID:12563177 diazoxon multiple interactions ISO Pon1 (Mus musculus) 6480464 PON1 affects the susceptibility to [diazoxon co-treated with malaoxon] CTD PMID:19371602 diazoxon affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of diazoxon and PON1 protein polymorphism affects the metabolism of diazoxon CTD PMID:15924216 and PMID:19071155 diazoxon affects hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the hydrolysis of diazoxon CTD PMID:10898114 dichlorvos multiple interactions EXP 6480464 1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein] more ... CTD PMID:20412842 and PMID:29098328 dichlorvos decreases activity EXP 6480464 Dichlorvos results in decreased activity of PON1 protein CTD PMID:29098328 dichlorvos decreases expression ISO Pon1 (Mus musculus) 6480464 Dichlorvos results in decreased expression of PON1 mRNA and Dichlorvos results in decreased expression of PON1 protein CTD PMID:25891459 dichlorvos multiple interactions ISO Pon1 (Mus musculus) 6480464 PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein] more ... CTD PMID:25891459 and PMID:26814074 dichlorvos decreases response to substance EXP 6480464 PON1 protein results in decreased susceptibility to Dichlorvos CTD PMID:20412842 diclofenac multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein and [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein CTD PMID:29512227 dieldrin multiple interactions EXP 6480464 [Dieldrin co-treated with NR1I2 protein] results in increased expression of PON1 mRNA more ... CTD PMID:24615737 diiodine multiple interactions EXP 6480464 [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein and [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 diisopropyl fluorophosphate increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Isoflurophate CTD PMID:20176006 and PMID:21382471 diisopropyl fluorophosphate multiple interactions ISO PON1 (Homo sapiens) 6480464 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Isoflurophate] CTD PMID:21382471 dimethylarsinic acid increases expression ISO Pon1 (Mus musculus) 6480464 Cacodylic Acid results in increased expression of PON1 mRNA CTD PMID:32052077 dioleoyl phosphatidylcholine multiple interactions ISO PON1 (Homo sapiens) 6480464 1 and 2-oleoylphosphatidylcholine inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein] CTD PMID:12871208 dioxygen multiple interactions ISO PON1 (Homo sapiens) 6480464 Oxygen promotes the reaction [PON1 protein affects the metabolism of Paraoxon] CTD PMID:16391483 dioxygen increases activity ISO PON1 (Homo sapiens) 6480464 Oxygen results in increased activity of PON1 protein CTD PMID:16391483 dipalmitoyl phosphatidylglycerol multiple interactions ISO PON1 (Homo sapiens) 6480464 1 and 2-dipalmitoylphosphatidylglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]] CTD PMID:15104111 disodium selenite decreases expression ISO PON1 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of PON1 mRNA CTD PMID:18175754 doramapimod decreases expression EXP 6480464 doramapimod results in decreased expression of PON1 mRNA CTD PMID:24303162 dorsomorphin multiple interactions ISO PON1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [Valproic Acid results in decreased activity of PON1 protein] CTD PMID:34309930 elemental selenium multiple interactions ISO PON1 (Homo sapiens) 6480464 Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein] and Selenium inhibits the reaction [Methylmercury Compounds results in decreased activity of PON1 protein] CTD PMID:21543280 endosulfan multiple interactions ISO PON1 (Homo sapiens) 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PON1 mRNA CTD PMID:26159488 entinostat increases expression ISO PON1 (Homo sapiens) 6480464 entinostat results in increased expression of PON1 mRNA CTD PMID:27188386 erucic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 erucic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein] CTD PMID:12871208 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb more ... CTD PMID:27132127 ethylene glycol bis(2-aminoethyl)tetraacetic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Egtazic Acid results in decreased activity of PON1 protein CTD PMID:27132127 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 [Egtazic Acid results in decreased activity of PON1 protein] which affects the susceptibility to O more ... CTD PMID:27132127 ethylene glycol bis(2-aminoethyl)tetraacetic acid decreases activity EXP 6480464 Egtazic Acid results in decreased activity of PON1 protein CTD PMID:27132127 farnesyl diphosphate multiple interactions ISO PON1 (Homo sapiens) 6480464 farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] and farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 and PMID:15690306 fenitrothion multiple interactions EXP 6480464 Fenitrothion promotes the reaction [Vehicle Emissions results in decreased activity of PON1 protein] more ... CTD PMID:32572764 and PMID:33439051 fenitrothion decreases expression EXP 6480464 Fenitrothion results in decreased expression of PON1 mRNA CTD PMID:32572764 and PMID:33439051 fenitrothion decreases activity EXP 6480464 Fenitrothion results in decreased activity of PON1 protein CTD PMID:32572764 fenofibrate increases expression ISO PON1 (Homo sapiens) 6480464 Fenofibrate results in increased expression of PON1 protein CTD PMID:16123850 flavone increases expression ISO PON1 (Homo sapiens) 6480464 flavone results in increased expression of PON1 mRNA CTD PMID:15169886 fluticasone decreases activity ISO PON1 (Homo sapiens) 6480464 Fluticasone results in decreased activity of PON1 protein CTD PMID:31581362 fluvastatin multiple interactions EXP 6480464 fluvastatin inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] and fluvastatin inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:14668577 fluvastatin decreases activity EXP 6480464 fluvastatin results in decreased activity of PON1 protein CTD PMID:14668577 fumonisin B1 decreases expression ISO Pon1 (Mus musculus) 6480464 fumonisin B1 results in decreased expression of PON1 mRNA CTD PMID:16221962 furan decreases expression EXP 6480464 furan results in decreased expression of PON1 mRNA CTD PMID:15120968 gabapentin decreases activity ISO PON1 (Homo sapiens) 6480464 gabapentin results in decreased activity of PON1 protein CTD PMID:28032682 gamma-decalactone increases hydrolysis EXP 6480464 PON1 protein results in increased hydrolysis of decan-4-olide CTD PMID:15829432 glutathione multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Glutathione] CTD PMID:20079818 graphene oxide decreases expression ISO Pon1 (Mus musculus) 6480464 graphene oxide results in decreased expression of PON1 mRNA CTD PMID:33227293 GW 4064 multiple interactions ISO PON1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [GW 4064 results in decreased expression of PON1 mRNA] CTD PMID:16269825 GW 4064 decreases expression ISO PON1 (Homo sapiens) 6480464 GW 4064 results in decreased expression of PON1 mRNA CTD PMID:16269825 high-density lipoprotein cholesterol affects abundance ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the abundance of Cholesterol more ... CTD PMID:16030523 more ... high-density lipoprotein cholesterol multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the reaction [Atorvastatin results in increased abundance of Cholesterol more ... CTD PMID:16238680 high-density lipoprotein cholesterol increases activity ISO PON1 (Homo sapiens) 6480464 Cholesterol and HDL results in increased activity of PON1 protein CTD PMID:16128586 high-density lipoprotein cholesterol affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to [APOA1 protein binds to Cholesterol and HDL] CTD PMID:16128586 homocysteine multiple interactions ISO Pon1 (Mus musculus) 6480464 [Methionine results in increased abundance of Homocysteine] which results in decreased activity of PON1 protein and [resveratrol results in increased abundance of Homocysteine] which results in decreased activity of PON1 protein CTD PMID:19028542 hydrazine decreases expression EXP 6480464 hydrazine results in decreased expression of PON1 mRNA and hydrazine results in decreased expression of PON1 protein CTD PMID:15370871 hydrogen peroxide multiple interactions ISO PON1 (Homo sapiens) 6480464 Hydrogen Peroxide inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] more ... CTD PMID:12871208 and PMID:15375178 hydrogen peroxide decreases activity ISO PON1 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased activity of PON1 protein CTD PMID:12871208 and PMID:15375178 hypochlorous acid decreases activity ISO PON1 (Homo sapiens) 6480464 Hypochlorous Acid results in decreased activity of PON1 protein CTD PMID:14671042 hypochlorous acid increases oxidation ISO PON1 (Homo sapiens) 6480464 Hypochlorous Acid results in increased oxidation of PON1 protein CTD PMID:15104111 hypochlorous acid multiple interactions ISO PON1 (Homo sapiens) 6480464 Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]] CTD PMID:15104111 iron atom multiple interactions ISO PON1 (Homo sapiens) 6480464 [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein more ... CTD PMID:16052486 iron atom multiple interactions EXP 6480464 [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein and [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein CTD PMID:16052486 iron(0) multiple interactions EXP 6480464 [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein and [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein CTD PMID:16052486 iron(0) multiple interactions ISO PON1 (Homo sapiens) 6480464 [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein more ... CTD PMID:16052486 iron(2+) sulfate (anhydrous) multiple interactions ISO PON1 (Homo sapiens) 6480464 [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] more ... CTD PMID:12871208 and PMID:15375178 isorhamnetin increases expression ISO PON1 (Homo sapiens) 6480464 3-methylquercetin results in increased expression of PON1 mRNA CTD PMID:20228421 L-ascorbic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 1 more ... CTD PMID:12871208 more ... L-ascorbic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Ascorbic Acid results in decreased activity of PON1 protein CTD PMID:15104111 L-ascorbic acid multiple interactions EXP 6480464 [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein and [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein CTD PMID:16052486 L-methionine multiple interactions ISO Pon1 (Mus musculus) 6480464 [Methionine results in increased abundance of Homocysteine] which results in decreased activity of PON1 protein CTD PMID:19028542 lead diacetate affects expression EXP 6480464 lead acetate affects the expression of PON1 mRNA CTD PMID:21864555 lead(0) decreases activity ISO PON1 (Homo sapiens) 6480464 Lead results in decreased activity of PON1 protein CTD PMID:16882531 lead(0) increases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP results in increased susceptibility to Lead CTD PMID:16882531 levetiracetam affects activity ISO PON1 (Homo sapiens) 6480464 Levetiracetam affects the activity of PON1 protein CTD PMID:28032682 levonorgestrel multiple interactions ISO Pon1 (Mus musculus) 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] affects the activity of PON1 protein CTD PMID:17541152 linoleic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] and Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:15375178 linoleic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Linoleic Acid results in decreased activity of PON1 protein CTD PMID:12871208 and PMID:15375178 lysophosphatidylglycerol decreases activity ISO PON1 (Homo sapiens) 6480464 lysophosphatidylglycerol results in decreased activity of PON1 protein CTD PMID:15375178 lysophosphatidylglycerol multiple interactions ISO PON1 (Homo sapiens) 6480464 lysophosphatidylglycerol inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:15375178 malaoxon multiple interactions ISO Pon1 (Mus musculus) 6480464 PON1 affects the susceptibility to [diazoxon co-treated with malaoxon] more ... CTD PMID:19371602 malonaldehyde multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:20079818 mefenamic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Palladium binds to Mefenamic Acid] which results in decreased activity of PON1 protein and [pyrrolidine analog binds to Platinum binds to Mefenamic Acid] which results in decreased activity of PON1 protein CTD PMID:29512227 mercury atom multiple interactions ISO PON1 (Homo sapiens) 6480464 Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein] CTD PMID:21543280 mercury atom decreases activity ISO PON1 (Homo sapiens) 6480464 Mercury results in decreased activity of PON1 protein CTD PMID:21543280 mercury(0) multiple interactions ISO PON1 (Homo sapiens) 6480464 Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein] CTD PMID:21543280 mercury(0) decreases activity ISO PON1 (Homo sapiens) 6480464 Mercury results in decreased activity of PON1 protein CTD PMID:21543280 metformin increases response to substance ISO Pon1 (Mus musculus) 6480464 PON1 gene mutant form results in increased susceptibility to Metformin CTD PMID:26945512 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of PON1 mRNA CTD PMID:30467583 methidathion decreases expression ISO Pon1 (Mus musculus) 6480464 methidathion results in decreased expression of PON1 mRNA CTD PMID:34813904 methimazole increases activity ISO PON1 (Homo sapiens) 6480464 Methimazole results in increased activity of PON1 protein CTD PMID:14678291 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of PON1 mRNA CTD PMID:15120968 methylglyoxal multiple interactions ISO PON1 (Homo sapiens) 6480464 Pyruvaldehyde inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] and Pyruvaldehyde inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:15375178 methylglyoxal decreases activity ISO PON1 (Homo sapiens) 6480464 Pyruvaldehyde results in decreased activity of PON1 protein CTD PMID:15375178 mevalonic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] more ... CTD PMID:14500290 and PMID:15690306 mithramycin multiple interactions ISO PON1 (Homo sapiens) 6480464 Plicamycin inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] CTD PMID:15690306 montelukast decreases activity ISO PON1 (Homo sapiens) 6480464 montelukast results in decreased activity of PON1 protein CTD PMID:31581362 moxifloxacin decreases activity ISO PON1 (Homo sapiens) 6480464 Moxifloxacin results in decreased activity of PON1 protein CTD PMID:31581362 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine affects the reaction [3 more ... CTD PMID:23644946 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PON1 mRNA and [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of PON1 protein CTD PMID:17602206 and PMID:20935162 N-nitrosodiethylamine multiple interactions ISO Pon1 (Mus musculus) 6480464 [2 more ... CTD PMID:23457121 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of PON1 mRNA CTD PMID:19041683 N-nitrosodiethylamine decreases expression ISO Pon1 (Mus musculus) 6480464 Diethylnitrosamine results in decreased expression of PON1 mRNA CTD PMID:24535843 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of PON1 protein CTD PMID:19716841 Nandrolone decanoate decreases activity ISO PON1 (Homo sapiens) 6480464 nandrolone decanoate results in decreased activity of PON1 protein CTD PMID:16153628 naphthalene decreases expression EXP 6480464 naphthalene analog results in decreased expression of PON1 mRNA CTD PMID:24976557 naphthalene decreases expression ISO Pon1 (Mus musculus) 6480464 naphthalene results in decreased expression of PON1 mRNA CTD PMID:18757308 nickel atom decreases expression ISO Pon1 (Mus musculus) 6480464 Nickel results in decreased expression of PON1 mRNA CTD PMID:12540486 nickel atom affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Nickel CTD PMID:23896426 nicotine decreases activity ISO PON1 (Homo sapiens) 6480464 Nicotine results in decreased activity of PON1 protein CTD PMID:24478552 nicotine multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP affects the susceptibility to [Pesticides co-treated with Nicotine] CTD PMID:29747151 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of PON1 mRNA CTD PMID:33484710 O-methyleugenol decreases expression ISO PON1 (Homo sapiens) 6480464 methyleugenol results in decreased expression of PON1 mRNA CTD PMID:32234424 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of PON1 mRNA CTD PMID:12700408 oleic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein more ... CTD PMID:12871208 more ... oleic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Oleic Acid results in decreased activity of PON1 protein CTD PMID:15375178 organophosphorus compound increases hydrolysis ISO Pon1 (Mus musculus) 6480464 PON1 protein results in increased hydrolysis of Organophosphorus Compounds CTD PMID:22209767 organophosphorus compound increases metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased metabolism of Organophosphorus Compounds CTD PMID:17078098 organophosphorus compound decreases expression ISO PON1 (Homo sapiens) 6480464 Organophosphorus Compounds results in decreased expression of PON1 protein CTD PMID:26340881 organophosphorus compound affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of Organophosphorus Compounds CTD PMID:15982977 organophosphorus compound multiple interactions ISO PON1 (Homo sapiens) 6480464 Oximes analog promotes the reaction [PON1 protein results in increased hydrolysis of and results in decreased activity of Organophosphorus Compounds] and PON1 protein results in increased hydrolysis of and results in decreased activity of Organophosphorus Compounds CTD PMID:25304213 organophosphorus compound increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Organophosphorus Compounds CTD PMID:22209767 organophosphorus compound affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene SNP affects the susceptibility to Organophosphorus Compounds and PON1 protein polymorphism affects the susceptibility to Organophosphorus Compounds CTD PMID:25867687 more ... orlistat increases activity ISO PON1 (Homo sapiens) 6480464 orlistat results in increased activity of PON1 protein CTD PMID:11820148 and PMID:17134960 oxamyl multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl and [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to oxamyl CTD PMID:27132127 oxamyl multiple interactions EXP 6480464 [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl and [Egtazic Acid results in decreased activity of PON1 protein] which affects the susceptibility to oxamyl CTD PMID:27132127 ozone decreases expression ISO Pon1 (Mus musculus) 6480464 Ozone results in decreased expression of PON1 mRNA CTD PMID:12763052 ozone multiple interactions ISO Pon1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PON1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PON1 mRNA CTD PMID:27106289 and PMID:34911549 ozone increases expression EXP 6480464 Ozone results in increased expression of PON1 protein CTD PMID:33146391 palladium multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein and [pyrrolidine analog binds to Palladium binds to Mefenamic Acid] which results in decreased activity of PON1 protein CTD PMID:29512227 palmitoleic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein] and palmitoleic acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:12871208 and PMID:15375178 palmitoleic acid decreases activity ISO PON1 (Homo sapiens) 6480464 palmitoleic acid results in decreased activity of PON1 protein CTD PMID:15375178 pamidronate multiple interactions EXP 6480464 [pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone more ... CTD PMID:27387541 pamidronate decreases activity EXP 6480464 pamidronate results in decreased activity of PON1 protein CTD PMID:27387541 panobinostat multiple interactions ISO PON1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PON1 mRNA CTD PMID:27188386 panobinostat decreases expression ISO PON1 (Homo sapiens) 6480464 panobinostat results in decreased expression of PON1 mRNA CTD PMID:26272509 paracetamol affects expression ISO Pon1 (Mus musculus) 6480464 Acetaminophen affects the expression of PON1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO PON1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PON1 mRNA CTD PMID:29067470 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PON1 protein CTD PMID:16099942 paraoxon increases activity ISO PON1 (Homo sapiens) 6480464 Paraoxon results in increased activity of PON1 protein CTD PMID:18519978 paraoxon decreases response to substance EXP 6480464 PON1 results in decreased susceptibility to Paraoxon CTD PMID:11022865 paraoxon multiple interactions ISO PON1 (Homo sapiens) 6480464 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] more ... CTD PMID:15375178 more ... paraoxon multiple interactions EXP 6480464 [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon more ... CTD PMID:14668577 more ... paraoxon decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in decreased susceptibility to Paraoxon CTD PMID:23159884 paraoxon increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in increased hydrolysis of Paraoxon and PON1 protein results in increased hydrolysis of Paraoxon CTD PMID:15375178 more ... paraoxon affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of Paraoxon and PON1 protein polymorphism affects the metabolism of Paraoxon CTD PMID:11304470 more ... paraoxon increases metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased metabolism of Paraoxon CTD PMID:21629682 paraoxon affects response to substance ISO PON1 (Homo sapiens) 6480464 PON1 gene polymorphism affects the susceptibility to Paraoxon CTD PMID:20839225 paraoxon affects hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 3' UTR SNP affects the hydrolysis of Paraoxon more ... CTD PMID:20839225 and PMID:9313934 paraoxon increases metabolic processing ISO Pon1 (Mus musculus) 6480464 PON1 protein results in increased metabolism of Paraoxon CTD PMID:23223497 paraoxon increases hydrolysis EXP 6480464 PON1 protein results in increased hydrolysis of Paraoxon CTD PMID:14668577 more ... Paraoxon-methyl multiple interactions EXP 6480464 [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon and [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to methylparaoxon CTD PMID:27132127 Paraoxon-methyl multiple interactions ISO PON1 (Homo sapiens) 6480464 [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon and [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to methylparaoxon CTD PMID:27132127 parathion increases metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 gene mutant form results in increased metabolism of Parathion CTD PMID:12625227 parathion increases expression ISO Pon1 (Mus musculus) 6480464 Parathion results in increased expression of PON1 mRNA CTD PMID:34813904 parathion increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of Parathion CTD PMID:16331452 parathion-methyl multiple interactions ISO PON1 (Homo sapiens) 6480464 Methyl Parathion results in decreased expression of and results in decreased activity of PON1 protein CTD PMID:26948828 parathion-methyl decreases expression ISO PON1 (Homo sapiens) 6480464 Methyl Parathion results in decreased expression of PON1 mRNA CTD PMID:26948828 pentane-2,3-dione decreases expression EXP 6480464 2 and 3-pentanedione results in decreased expression of PON1 mRNA CTD PMID:25710175 perfluorononanoic acid decreases expression ISO PON1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of PON1 mRNA CTD PMID:32588087 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of PON1 mRNA CTD PMID:19162173 perfluorooctanoic acid decreases expression ISO Pon1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of PON1 mRNA CTD PMID:17681415 more ... perfluorooctanoic acid multiple interactions ISO Pon1 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with Dietary Fats more ... CTD PMID:20118188 and PMID:23626681 permethrin increases expression EXP 6480464 Permethrin results in increased expression of PON1 mRNA CTD PMID:31175960 phenobarbital multiple interactions EXP 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of PON1 protein CTD PMID:20935162 phenobarbital increases expression ISO Pon1 (Mus musculus) 6480464 Phenobarbital results in increased expression of PON1 mRNA and Phenobarbital results in increased expression of PON1 protein CTD PMID:28218408 and PMID:28541575 phenobarbital multiple interactions ISO Pon1 (Mus musculus) 6480464 NR1I3 gene mutant form inhibits the reaction [Phenobarbital results in increased expression of PON1 mRNA] CTD PMID:28218408 phenobarbital decreases expression ISO Pon1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of PON1 mRNA CTD PMID:22653878 phenobarbital affects expression ISO PON1 (Homo sapiens) 6480464 Phenobarbital affects the expression of PON1 mRNA CTD PMID:19159669 phenyl acetate affects hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 3' UTR SNP affects the hydrolysis of phenyl acetate more ... CTD PMID:20839225 phenyl acetate multiple interactions ISO PON1 (Homo sapiens) 6480464 [Polyethylene Glycols binds to PON1 protein] which results in increased hydrolysis of phenyl acetate CTD PMID:22414384 phenyl acetate increases hydrolysis EXP 6480464 PON1 protein results in increased hydrolysis of phenyl acetate CTD PMID:22414384 phenyl acetate multiple interactions EXP 6480464 [Alendronate results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate more ... CTD PMID:27387541 phenyl acetate affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 SNP affects the metabolism of phenyl acetate CTD PMID:25027835 phenyl acetate increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of phenyl acetate CTD PMID:22414384 phenylacetic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 4-hydroxy-2-nonenal inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] more ... CTD PMID:15375178 phenylacetic acid affects metabolic processing ISO PON1 (Homo sapiens) 6480464 PON1 protein affects the metabolism of phenylacetic acid and PON1 protein polymorphism affects the metabolism of phenylacetic acid CTD PMID:11304470 more ... phenylacetic acid increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein results in increased hydrolysis of phenylacetic acid CTD PMID:15375178 more ... phenylacetic acid increases hydrolysis EXP 6480464 PON1 protein results in increased hydrolysis of phenylacetic acid CTD PMID:14668577 and PMID:16052486 phenylacetic acid multiple interactions EXP 6480464 fluvastatin inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] CTD PMID:14668577 phenylacetic acid decreases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 promoter SNP results in decreased hydrolysis of phenylacetic acid CTD PMID:16117861 phenylmercury acetate multiple interactions ISO PON1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PON1 mRNA CTD PMID:27188386 phenytoin decreases expression ISO Pon1 (Mus musculus) 6480464 Phenytoin results in decreased expression of PON1 mRNA CTD PMID:15136057 phenytoin affects activity ISO PON1 (Homo sapiens) 6480464 Phenytoin affects the activity of PON1 protein CTD PMID:28032682 pirinixic acid multiple interactions ISO PON1 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PON1 mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO Pon1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of PON1 mRNA CTD PMID:16221962 pitavastatin increases expression ISO PON1 (Homo sapiens) 6480464 pitavastatin results in increased expression of PON1 mRNA CTD PMID:15690306 pitavastatin multiple interactions ISO PON1 (Homo sapiens) 6480464 farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] more ... CTD PMID:15690306 pitavastatin(1-) increases expression ISO PON1 (Homo sapiens) 6480464 pitavastatin results in increased expression of PON1 mRNA CTD PMID:15690306 pitavastatin(1-) multiple interactions ISO PON1 (Homo sapiens) 6480464 farnesyl pyrophosphate inhibits the reaction [pitavastatin results in increased expression of PON1 mRNA] more ... CTD PMID:15690306 platinum multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein and [pyrrolidine analog binds to Platinum binds to Mefenamic Acid] which results in decreased activity of PON1 protein CTD PMID:29512227 platinum(0) multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Platinum binds to Diclofenac] which results in decreased activity of PON1 protein and [pyrrolidine analog binds to Platinum binds to Mefenamic Acid] which results in decreased activity of PON1 protein CTD PMID:29512227 potassium dichromate affects expression ISO Pon1 (Mus musculus) 6480464 Potassium Dichromate affects the expression of PON1 mRNA CTD PMID:23608068 pralidoxime multiple interactions EXP 6480464 pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein] CTD PMID:29098328 pregnenolone 16alpha-carbonitrile decreases expression ISO Pon1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of PON1 mRNA CTD PMID:28903501 primidone decreases activity ISO PON1 (Homo sapiens) 6480464 Primidone results in decreased activity of PON1 protein CTD PMID:28032682 proanthocyanidin multiple interactions EXP 6480464 Proanthocyanidins inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein] CTD PMID:30273964 propanal increases expression ISO PON1 (Homo sapiens) 6480464 propionaldehyde results in increased expression of PON1 mRNA CTD PMID:26079696 pyrrolidine multiple interactions ISO PON1 (Homo sapiens) 6480464 [pyrrolidine analog binds to Palladium binds to Diclofenac] which results in decreased activity of PON1 protein more ... CTD PMID:29512227 quercetin increases expression ISO Pon1 (Mus musculus) 6480464 Quercetin results in increased expression of PON1 mRNA and Quercetin results in increased expression of PON1 protein CTD PMID:20228421 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fenitrothion results in decreased expression of PON1 mRNA] CTD PMID:33439051 quercetin multiple interactions ISO Pon1 (Mus musculus) 6480464 Quercetin inhibits the reaction [Dietary Fats results in decreased expression of PON1 mRNA] and Quercetin inhibits the reaction [Dietary Fats results in decreased expression of PON1 protein] CTD PMID:22447684 quercetin increases expression ISO PON1 (Homo sapiens) 6480464 Quercetin results in increased expression of PON1 mRNA and Quercetin results in increased expression of PON1 protein CTD PMID:15169886 and PMID:20728021 quercetin increases activity EXP 6480464 Quercetin results in increased activity of PON1 protein CTD PMID:19141295 quercetin increases expression EXP 6480464 Quercetin results in increased expression of PON1 mRNA CTD PMID:19141295 quercetin increases activity ISO PON1 (Homo sapiens) 6480464 Quercetin results in increased activity of PON1 protein CTD PMID:15169886 quercetin multiple interactions ISO PON1 (Homo sapiens) 6480464 7-ketocholesterol inhibits the reaction [Quercetin results in increased expression of PON1 mRNA] more ... CTD PMID:15169886 and PMID:20728021 quinolin-2(1H)-one multiple interactions ISO PON1 (Homo sapiens) 6480464 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Isoflurophate] and 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:21382471 quinolin-2-ol multiple interactions ISO PON1 (Homo sapiens) 6480464 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Isoflurophate] and 2-hydroxyquinoline inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] CTD PMID:21382471 reactive oxygen species decreases activity ISO PON1 (Homo sapiens) 6480464 Reactive Oxygen Species results in decreased activity of PON1 protein CTD PMID:16055108 resveratrol multiple interactions ISO PON1 (Homo sapiens) 6480464 7-ketocholesterol inhibits the reaction [resveratrol results in increased expression of PON1 mRNA] more ... CTD PMID:15458977 more ... resveratrol multiple interactions ISO Pon1 (Mus musculus) 6480464 [resveratrol results in increased abundance of Homocysteine] which results in decreased activity of PON1 protein CTD PMID:19028542 resveratrol increases expression ISO Pon1 (Mus musculus) 6480464 resveratrol results in increased expression of PON1 mRNA and resveratrol results in increased expression of PON1 protein CTD PMID:18930334 resveratrol increases expression ISO PON1 (Homo sapiens) 6480464 resveratrol results in increased expression of PON1 mRNA and resveratrol results in increased expression of PON1 protein CTD PMID:15458977 more ... resveratrol increases activity ISO PON1 (Homo sapiens) 6480464 resveratrol results in increased activity of PON1 protein CTD PMID:15458977 rifampicin increases expression ISO PON1 (Homo sapiens) 6480464 Rifampin results in increased expression of PON1 mRNA CTD PMID:26434531 Risedronate sodium increases activity EXP 6480464 Risedronic Acid results in increased activity of PON1 protein CTD PMID:27387541 Risedronate sodium multiple interactions EXP 6480464 [Risedronic Acid results in increased activity of PON1 protein] which results in increased metabolism of homocysteine thiolactone more ... CTD PMID:27387541 ritonavir decreases activity EXP 6480464 Ritonavir results in decreased activity of PON1 protein CTD PMID:27378623 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 mRNA] and Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 protein] CTD PMID:25478064 rutin increases expression EXP 6480464 Rutin results in increased expression of PON1 mRNA CTD PMID:25478064 salicylates increases expression ISO PON1 (Homo sapiens) 6480464 Salicylates results in increased expression of PON1 mRNA CTD PMID:18519978 salicylates increases activity ISO PON1 (Homo sapiens) 6480464 Salicylates results in increased activity of PON1 protein CTD PMID:18519978 saquinavir decreases activity EXP 6480464 Saquinavir results in decreased activity of PON1 protein CTD PMID:27378623 sarin multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein] and PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein] CTD PMID:21329748 sarin increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in increased hydrolysis of Sarin and PON1 protein results in increased hydrolysis of Sarin CTD PMID:16331452 more ... sarin decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in decreased susceptibility to Sarin CTD PMID:23159884 SB 431542 multiple interactions ISO PON1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenic acid increases activity EXP 6480464 Selenic Acid deficiency results in increased activity of PON1 protein CTD PMID:23644946 selenic acid decreases expression EXP 6480464 Selenic Acid results in decreased expression of PON1 mRNA CTD PMID:23644946 selenic acid multiple interactions EXP 6480464 Selenic Acid deficiency inhibits the reaction [3 more ... CTD PMID:23644946 selenium atom multiple interactions ISO PON1 (Homo sapiens) 6480464 Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein] and Selenium inhibits the reaction [Methylmercury Compounds results in decreased activity of PON1 protein] CTD PMID:21543280 silicon dioxide decreases expression ISO PON1 (Homo sapiens) 6480464 Silicon Dioxide results in decreased expression of PON1 mRNA and Silicon Dioxide results in decreased expression of PON1 protein CTD PMID:19679115 simvastatin multiple interactions ISO PON1 (Homo sapiens) 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] more ... CTD PMID:14500290 and PMID:16238680 simvastatin increases expression ISO PON1 (Homo sapiens) 6480464 Simvastatin results in increased expression of PON1 mRNA CTD PMID:14500290 and PMID:15690306 sodium arsenite decreases methylation ISO Pon1 (Mus musculus) 6480464 sodium arsenite results in decreased methylation of PON1 gene CTD PMID:32068019 sodium arsenite decreases expression ISO PON1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of PON1 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO Pon1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of PON1 mRNA CTD PMID:17350061 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of PON1 mRNA CTD PMID:12325037 sodium fluoride decreases activity EXP 6480464 Sodium Fluoride results in decreased activity of PON1 protein CTD PMID:24384758 sodium perchlorate multiple interactions EXP 6480464 [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein and [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 sodium selenate multiple interactions EXP 401794573 sodium selenate inhibits the reaction [3 more ... RGD Soman decreases response to substance ISO Pon1 (Mus musculus) 6480464 PON1 protein results in decreased susceptibility to Soman CTD PMID:15707963 Soman increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in increased hydrolysis of Soman and PON1 protein results in increased hydrolysis of Soman CTD PMID:16331452 more ... Soman decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in decreased susceptibility to Soman CTD PMID:23159884 Soman multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein inhibits the reaction [Soman results in decreased activity of ACHE protein] and PON1 protein inhibits the reaction [Soman results in decreased activity of BCHE protein] CTD PMID:21329748 Soman increases hydrolysis ISO Pon1 (Mus musculus) 6480464 PON1 protein results in increased hydrolysis of Soman CTD PMID:15707963 squalene multiple interactions ISO PON1 (Homo sapiens) 6480464 Squalene inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 streptozocin multiple interactions EXP 6480464 [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA more ... CTD PMID:31400774 streptozocin decreases activity EXP 6480464 Streptozocin results in decreased activity of PON1 protein CTD PMID:34039237 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of PON1 mRNA and Streptozocin results in decreased expression of PON1 protein CTD PMID:31400774 sulfisomidine decreases activity ISO PON1 (Homo sapiens) 6480464 Sulfisomidine results in decreased activity of PON1 protein CTD PMID:28665493 sulfisoxazole decreases activity ISO PON1 (Homo sapiens) 6480464 Sulfisoxazole results in decreased activity of PON1 protein CTD PMID:28665493 tamoxifen decreases expression ISO Pon1 (Mus musculus) 6480464 Tamoxifen results in decreased expression of PON1 mRNA CTD PMID:25123088 taurocholic acid multiple interactions ISO Pon1 (Mus musculus) 6480464 FGFR4 protein affects the reaction [Taurocholic Acid results in decreased expression of PON1 mRNA] and NR1H4 protein affects the reaction [Taurocholic Acid results in decreased expression of PON1 mRNA] CTD PMID:16284190 taurocholic acid decreases expression ISO Pon1 (Mus musculus) 6480464 Taurocholic Acid results in decreased expression of PON1 mRNA CTD PMID:16284190 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PON1 mRNA and Carbon Tetrachloride results in decreased expression of PON1 protein CTD PMID:25478064 and PMID:31150632 tetrachloromethane decreases expression ISO Pon1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of PON1 mRNA CTD PMID:31919559 tetrachloromethane decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein results in decreased susceptibility to Carbon Tetrachloride CTD PMID:20079818 tetrachloromethane multiple interactions ISO PON1 (Homo sapiens) 6480464 PON1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Glutathione] more ... CTD PMID:20079818 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of PON1 mRNA CTD PMID:12734012 tetrachloromethane multiple interactions EXP 6480464 Rutin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PON1 mRNA] more ... CTD PMID:25478064 and PMID:31150632 theophylline decreases activity ISO PON1 (Homo sapiens) 6480464 Theophylline results in decreased activity of PON1 protein CTD PMID:31581362 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PON1 mRNA CTD PMID:34492290 tiotropium bromide decreases activity ISO PON1 (Homo sapiens) 6480464 Tiotropium Bromide results in decreased activity of PON1 protein CTD PMID:31581362 titanium dioxide decreases expression ISO Pon1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of PON1 mRNA CTD PMID:23557971 trichostatin A decreases expression ISO PON1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of PON1 mRNA CTD PMID:24935251 valproic acid affects expression ISO PON1 (Homo sapiens) 6480464 Valproic Acid affects the expression of PON1 mRNA CTD PMID:25979313 valproic acid decreases activity EXP 6480464 Valproic Acid results in decreased activity of PON1 protein CTD PMID:34309930 valproic acid multiple interactions EXP 6480464 Edaravone inhibits the reaction [Valproic Acid results in decreased activity of PON1 protein] CTD PMID:34309930 valproic acid decreases activity ISO PON1 (Homo sapiens) 6480464 Valproic Acid results in decreased activity of PON1 protein CTD PMID:28032682 valproic acid increases expression ISO PON1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PON1 mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO PON1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PON1 mRNA CTD PMID:29154799 valproic acid decreases methylation ISO PON1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of PON1 gene CTD PMID:29154799 vancomycin decreases activity EXP 6480464 Vancomycin results in decreased activity of PON1 protein CTD PMID:31454121 vancomycin multiple interactions EXP 6480464 zingerone affects the reaction [Vancomycin results in decreased activity of PON1 protein] CTD PMID:31454121 varenicline decreases activity ISO PON1 (Homo sapiens) 6480464 Varenicline results in decreased activity of PON1 protein CTD PMID:31581362 vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [Propylthiouracil results in decreased activity of PON1 protein] CTD PMID:15386442 vitamin E increases activity EXP 6480464 Vitamin E results in increased activity of PON1 protein CTD PMID:15386442 vorinostat decreases expression ISO PON1 (Homo sapiens) 6480464 vorinostat results in decreased expression of PON1 mRNA CTD PMID:26272509 vorinostat multiple interactions ISO PON1 (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PON1 mRNA CTD PMID:27188386 VX nerve agent increases hydrolysis ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in increased hydrolysis of VX and PON1 protein results in increased hydrolysis of VX CTD PMID:20176005 and PMID:23159884 VX nerve agent decreases response to substance ISO PON1 (Homo sapiens) 6480464 PON1 protein mutant form results in decreased susceptibility to VX CTD PMID:23159884 zinc atom affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Zinc CTD PMID:23896426 zinc(0) affects binding ISO PON1 (Homo sapiens) 6480464 PON1 protein binds to Zinc CTD PMID:23896426 zingerone multiple interactions EXP 6480464 zingerone affects the reaction [Vancomycin results in decreased activity of PON1 protein] CTD PMID:31454121 zingerone affects activity EXP 6480464 zingerone affects the activity of PON1 protein CTD PMID:31454121 zoledronic acid increases activity EXP 6480464 zoledronic acid results in increased activity of PON1 protein CTD PMID:27387541 zoledronic acid multiple interactions EXP 6480464 [zoledronic acid results in increased activity of PON1 protein] which results in increased metabolism of phenyl acetate CTD PMID:27387541