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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620062
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pon1
Name: paraoxonase 1
Acc ID: CHEBI:30740
Term: ethylene glycol bis(2-aminoethyl)tetraacetic acid
Definition: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
Chemical ID: MESH:D004533
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pon1decreases activityEXP 6480464CTDEgtazic Acid results in decreased activity of PON1 proteinPMID:27132127
Pon1multiple interactionsEXP 6480464CTD[Egtazic Acid results in decreased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Egtazic Acid results in decreased activity of PON1 protein] which affects the susceptibility to oxamyl; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to methylparaoxon; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to ParaoxonPMID:27132127
Pon1decreases activityISOPON1 (Homo sapiens)6480464CTDEgtazic Acid results in decreased activity of PON1 proteinPMID:27132127
Pon1multiple interactionsISOPON1 (Homo sapiens)6480464CTD[Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to methylparaoxon; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to oxamyl; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to ParaoxonPMID:27132127
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