GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pon1 | multiple interactions | EXP | | 6480464 | CTD | Atorvastatin inhibits the reaction [[Cholesterol co-treated with Cholic Acid] results in decreased secretion of PON1 protein] | PMID:30273964 | Pon1 | increases activity | ISO | PON1 (Homo sapiens) | 6480464 | CTD | Atorvastatin results in increased activity of PON1 protein | PMID:15324535 PMID:15969877 | Pon1 | increases expression | ISO | PON1 (Homo sapiens) | 6480464 | CTD | Atorvastatin results in increased expression of PON1 mRNA | PMID:15690306 | Pon1 | multiple interactions | ISO | PON1 (Homo sapiens) | 6480464 | CTD | PON1 gene polymorphism affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 gene SNP affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL]; PON1 protein affects the reaction [Atorvastatin results in increased abundance of Cholesterol, HDL] | PMID:16238680 | | ||||||||||||||||||||||
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