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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620062
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pon1
Name: paraoxonase 1
Acc ID: CHEBI:2555
Term: aldicarb
Definition: The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active.
Chemical ID: MESH:D000448
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pon1multiple interactionsEXP 6480464CTD[Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb

PMID:27132127
Pon1multiple interactionsISORGD:13492726480464CTD[Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to Aldicarb

PMID:27132127
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