Trdn (triadin) - Rat Genome Database

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Gene: Trdn (triadin) Rattus norvegicus
Analyze
Symbol: Trdn
Name: triadin
RGD ID: 619856
Description: Predicted to enable protein-macromolecule adaptor activity. Involved in several processes, including cytoplasmic microtubule organization; myotube differentiation; and regulation of release of sequestered calcium ion into cytosol. Located in junctional sarcoplasmic reticulum membrane and plasma membrane. Part of calcium channel complex and junctional membrane complex. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Orthologous to human TRDN (triadin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: triadin 1; triadin 32 kDa (TRISK 32); triadin 49 kDa (TRISK 49); triadin 95
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: TrdnTn(sb-T2/Bart3)2.238Mcwi  
Genetic Models: F344-TrdnTn(sb-T2/Bart3)2.238Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8125,774,765 - 26,230,069 (-)NCBIGRCr8
mRatBN7.2123,955,651 - 24,410,494 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl123,955,651 - 24,410,595 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx123,712,731 - 24,162,882 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0129,712,475 - 30,162,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0123,909,818 - 24,359,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0125,403,390 - 25,787,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl125,403,390 - 25,839,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0126,865,461 - 27,248,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,514,752 - 24,925,948 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1124,517,697 - 24,980,460 (-)NCBI
Celera122,661,681 - 23,059,882 (-)NCBICelera
Cytogenetic Map1p12-p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Immunolocalization of triadin, DHP receptors, and ryanodine receptors in adult and developing skeletal muscle of rats. Carl SL, etal., Muscle Nerve. 1995 Nov;18(11):1232-43.
2. Altered expression of triadin 95 causes parallel changes in localized Ca2+ release events and global Ca2+ signals in skeletal muscle cells in culture. Fodor J, etal., J Physiol. 2008 Dec 1;586(Pt 23):5803-18. Epub 2008 Oct 9.
3. Role of triadin in the organization of reticulum membrane at the muscle triad. Fourest-Lieuvin A, etal., J Cell Sci. 2012 Jul 15;125(Pt 14):3443-53. doi: 10.1242/jcs.100958. Epub 2012 Apr 14.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. On the role of junctin in cardiac Ca2+ handling, contractility, and heart failure. Gergs U, etal., Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H728-34. Epub 2007 Mar 30.
6. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
7. Cloning and characterization of a new isoform of skeletal muscle triadin. Marty I, etal., J Biol Chem 2000 Mar 17;275(11):8206-12.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. Trisk 32 regulates IP(3) receptors in rat skeletal myoblasts. Olah T, etal., Pflugers Arch. 2011 Oct;462(4):599-610. doi: 10.1007/s00424-011-1001-y. Epub 2011 Aug 3.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. Luminal Ca2+ regulation of single cardiac ryanodine receptors: insights provided by calsequestrin and its mutants. Qin J, etal., J Gen Physiol. 2008 Apr;131(4):325-34. Epub 2008 Mar 17.
13. Triadin (Trisk 95) overexpression blocks excitation-contraction coupling in rat skeletal myotubes. Rezgui SS, etal., J Biol Chem. 2005 Nov 25;280(47):39302-8. Epub 2005 Sep 21.
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human. Roux-Buisson N, etal., Hum Mol Genet. 2012 Jun 15;21(12):2759-67. doi: 10.1093/hmg/dds104. Epub 2012 Mar 14.
18. Gene expression profiles following exposure to a developmental neurotoxicant, Aroclor 1254: pathway analysis for possible mode(s) of action. Royland JE and Kodavanti PR, Toxicol Appl Pharmacol. 2008 Sep 1;231(2):179-96. Epub 2008 May 6.
19. Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes. Terentyev D, etal., J Physiol. 2007 Aug 15;583(Pt 1):71-80. Epub 2007 Jun 14.
20. Retrograde regulation of store-operated calcium channels by the ryanodine receptor-associated protein triadin 95 in rat skeletal myotubes. Vassilopoulos S, etal., Cell Calcium. 2007 Feb;41(2):179-85. Epub 2006 Aug 4.
Additional References at PubMed
PMID:9287354   PMID:12955494   PMID:15041652   PMID:15731460   PMID:15927957   PMID:18025088   PMID:19383796   PMID:23012479   PMID:37589058  


Genomics

Comparative Map Data
Trdn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8125,774,765 - 26,230,069 (-)NCBIGRCr8
mRatBN7.2123,955,651 - 24,410,494 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl123,955,651 - 24,410,595 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx123,712,731 - 24,162,882 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0129,712,475 - 30,162,651 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0123,909,818 - 24,359,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0125,403,390 - 25,787,664 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl125,403,390 - 25,839,345 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0126,865,461 - 27,248,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4124,514,752 - 24,925,948 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1124,517,697 - 24,980,460 (-)NCBI
Celera122,661,681 - 23,059,882 (-)NCBICelera
Cytogenetic Map1p12-p11NCBI
TRDN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386123,216,339 - 123,636,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6123,216,339 - 123,637,189 (-)EnsemblGRCh38hg38GRCh38
GRCh376123,537,484 - 123,958,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366123,579,182 - 123,999,641 (-)NCBINCBI36Build 36hg18NCBI36
Build 346123,580,714 - 123,999,641NCBI
Celera6124,281,651 - 124,701,991 (-)NCBICelera
Cytogenetic Map6q22.31NCBI
HuRef6121,115,183 - 121,535,579 (-)NCBIHuRef
CHM1_16123,801,225 - 124,221,793 (-)NCBICHM1_1
T2T-CHM13v2.06124,404,293 - 124,824,746 (-)NCBIT2T-CHM13v2.0
Trdn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391032,959,479 - 33,352,705 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1032,956,550 - 33,352,705 (+)EnsemblGRCm39 Ensembl
GRCm381033,083,483 - 33,476,709 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1033,080,554 - 33,476,709 (+)EnsemblGRCm38mm10GRCm38
MGSCv371032,803,289 - 33,196,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361032,772,897 - 32,923,408 (+)NCBIMGSCv36mm8
Celera1033,991,863 - 34,385,108 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1018.37NCBI
Trdn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554364,963,945 - 5,266,727 (-)NCBIChiLan1.0ChiLan1.0
TRDN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25143,213,514 - 143,630,282 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16141,115,209 - 141,534,159 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06121,010,234 - 121,424,644 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16125,133,827 - 125,546,854 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6125,134,433 - 125,546,537 (-)Ensemblpanpan1.1panPan2
TRDN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1162,402,763 - 62,762,717 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl162,402,642 - 62,762,722 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha163,211,629 - 63,571,581 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0162,604,717 - 62,967,214 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl162,606,830 - 62,967,138 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1162,540,244 - 62,899,794 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0162,328,116 - 62,688,183 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0162,976,846 - 63,337,432 (-)NCBIUU_Cfam_GSD_1.0
LOC101962457
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946113,572,732 - 113,686,223 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936802389,653 - 637,372 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRDN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl139,180,913 - 39,567,240 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1139,180,544 - 39,567,245 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2143,518,886 - 43,723,161 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRDN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11350,145,787 - 50,580,397 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604022,476,403 - 22,891,592 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trdn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247987,780,362 - 8,018,719 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trdn
2885 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:86
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000017428, ENSRNOT00000042072, ENSRNOT00000067280
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1592587724697545Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.50.00000072tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat

Markers in Region
D1Wox82  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2124,050,521 - 24,050,671 (+)MAPPERmRatBN7.2
Rnor_6.0125,500,229 - 25,500,378NCBIRnor6.0
Rnor_5.0126,960,748 - 26,960,897UniSTSRnor5.0
RGSC_v3.4124,610,373 - 24,610,522UniSTSRGSC3.4
Celera122,756,634 - 22,756,783UniSTS
Cytogenetic Map1p11UniSTS
RH128748  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2124,047,215 - 24,047,395 (+)MAPPERmRatBN7.2
Rnor_6.0125,496,923 - 25,497,102NCBIRnor6.0
Rnor_5.0126,957,442 - 26,957,621UniSTSRnor5.0
RGSC_v3.4124,607,067 - 24,607,246UniSTSRGSC3.4
Celera122,753,328 - 22,753,507UniSTS
RH 3.4 Map1240.7UniSTS
Cytogenetic Map1p11UniSTS
RH139255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2124,283,170 - 24,283,314 (+)MAPPERmRatBN7.2
Rnor_6.0125,711,135 - 25,711,278NCBIRnor6.0
Rnor_5.0127,172,186 - 27,172,329UniSTSRnor5.0
RGSC_v3.4124,849,443 - 24,849,586UniSTSRGSC3.4
Celera122,983,754 - 22,983,897UniSTS
Cytogenetic Map1p11UniSTS
AA849413  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2124,068,403 - 24,068,497 (+)MAPPERmRatBN7.2
Rnor_6.0125,517,227 - 25,517,320NCBIRnor6.0
Rnor_5.0126,977,746 - 26,977,839UniSTSRnor5.0
RGSC_v3.4124,628,410 - 24,628,503UniSTSRGSC3.4
Celera122,774,368 - 22,774,461UniSTS
RH 3.4 Map1241.6UniSTS
Cytogenetic Map1p11UniSTS
AI172006  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2123,955,862 - 23,956,005 (+)MAPPERmRatBN7.2
Rnor_6.0125,403,602 - 25,403,744NCBIRnor6.0
Rnor_5.0126,865,673 - 26,865,815UniSTSRnor5.0
RGSC_v3.4124,514,964 - 24,515,106UniSTSRGSC3.4
Celera122,661,893 - 22,662,035UniSTS
RH 3.4 Map1241.6UniSTS
Cytogenetic Map1p11UniSTS


Genetic Models
This gene Trdn is modified in the following models/strains:
F344-TrdnTn(sb-T2/Bart3)2.238Mcwi    


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 8 11 6 8
Low 1 17 8 7 8 16 12 3
Below cutoff 2 15 8 9 8 48 25 21 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_021666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF220558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF220559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ243304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ812275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ812276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000042072   ⟹   ENSRNOP00000041570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl123,955,651 - 24,410,595 (-)Ensembl
Rnor_6.0 Ensembl125,405,369 - 25,839,345 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090388   ⟹   ENSRNOP00000069016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl123,955,651 - 24,410,595 (-)Ensembl
Rnor_6.0 Ensembl125,403,390 - 25,839,198 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092757   ⟹   ENSRNOP00000076056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl123,955,651 - 24,410,595 (-)Ensembl
Rnor_6.0 Ensembl125,716,396 - 25,839,279 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093030   ⟹   ENSRNOP00000075929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl124,212,949 - 24,410,595 (-)Ensembl
Rnor_6.0 Ensembl125,655,253 - 25,787,619 (-)Ensembl
RefSeq Acc Id: NM_021666   ⟹   NP_067698
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,229,599 (-)NCBI
mRatBN7.2123,955,651 - 24,410,494 (-)NCBI
Rnor_6.0125,403,390 - 25,787,664 (-)NCBI
Rnor_5.0126,865,461 - 27,248,423 (-)NCBI
RGSC_v3.4124,514,752 - 24,925,948 (-)RGD
Celera122,661,681 - 23,059,882 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272290   ⟹   XP_063128360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272296   ⟹   XP_063128366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272299   ⟹   XP_063128369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272302   ⟹   XP_063128372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272306   ⟹   XP_063128376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272311   ⟹   XP_063128381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272312   ⟹   XP_063128382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272316   ⟹   XP_063128386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272319   ⟹   XP_063128389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272320   ⟹   XP_063128390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272323   ⟹   XP_063128393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272326   ⟹   XP_063128396
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,774,765 - 26,229,805 (-)NCBI
RefSeq Acc Id: XM_063272330   ⟹   XP_063128400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,866,197 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272332   ⟹   XP_063128402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,866,197 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272337   ⟹   XP_063128407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,866,197 - 26,230,069 (-)NCBI
RefSeq Acc Id: XM_063272343   ⟹   XP_063128413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8125,927,987 - 26,230,069 (-)NCBI
Protein Sequences
Protein RefSeqs NP_067698 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128360 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128366 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128369 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128372 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128376 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128381 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128382 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128386 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128389 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128390 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128393 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128396 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128400 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128402 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128407 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128413 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF29539 (Get FASTA)   NCBI Sequence Viewer  
  AAF29540 (Get FASTA)   NCBI Sequence Viewer  
  CAB64603 (Get FASTA)   NCBI Sequence Viewer  
  CAB64604 (Get FASTA)   NCBI Sequence Viewer  
  CAH23273 (Get FASTA)   NCBI Sequence Viewer  
  CAH23274 (Get FASTA)   NCBI Sequence Viewer  
  EDL87716 (Get FASTA)   NCBI Sequence Viewer  
  EDL87717 (Get FASTA)   NCBI Sequence Viewer  
  EDL87718 (Get FASTA)   NCBI Sequence Viewer  
  EDL87719 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000041570.6
  ENSRNOP00000069016
  ENSRNOP00000069016.3
  ENSRNOP00000075929.2
  ENSRNOP00000076056.2
GenBank Protein Q9QX75 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_067698   ⟸   NM_021666
- UniProtKB: Q9QX76 (UniProtKB/Swiss-Prot),   Q9QX75 (UniProtKB/Swiss-Prot),   Q9JKZ6 (UniProtKB/Swiss-Prot),   Q9JKZ5 (UniProtKB/Swiss-Prot),   Q5DVI7 (UniProtKB/Swiss-Prot),   Q5DVI6 (UniProtKB/Swiss-Prot),   E9PTN7 (UniProtKB/Swiss-Prot),   A6JUQ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000076056   ⟸   ENSRNOT00000092757
RefSeq Acc Id: ENSRNOP00000069016   ⟸   ENSRNOT00000090388
RefSeq Acc Id: ENSRNOP00000041570   ⟸   ENSRNOT00000042072
RefSeq Acc Id: ENSRNOP00000075929   ⟸   ENSRNOT00000093030
RefSeq Acc Id: XP_063128390   ⟸   XM_063272320
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063128386   ⟸   XM_063272316
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063128376   ⟸   XM_063272306
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063128393   ⟸   XM_063272323
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063128382   ⟸   XM_063272312
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063128389   ⟸   XM_063272319
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063128372   ⟸   XM_063272302
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063128381   ⟸   XM_063272311
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063128369   ⟸   XM_063272299
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063128366   ⟸   XM_063272296
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128360   ⟸   XM_063272290
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128396   ⟸   XM_063272326
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063128402   ⟸   XM_063272332
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063128407   ⟸   XM_063272337
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063128400   ⟸   XM_063272330
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063128413   ⟸   XM_063272343
- Peptide Label: isoform X16
Protein Domains
Aspartyl beta-hydroxylase/Triadin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QX75-F1-model_v2 AlphaFold Q9QX75 1-687 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619856 AgrOrtholog
BioCyc Gene G2FUF-62001 BioCyc
Ensembl Genes ENSRNOG00000012609 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042072.7 UniProtKB/TrEMBL
  ENSRNOT00000090388 ENTREZGENE
  ENSRNOT00000090388.3 UniProtKB/TrEMBL
  ENSRNOT00000092757.2 UniProtKB/TrEMBL
  ENSRNOT00000093030.2 UniProtKB/TrEMBL
InterPro Asp-B-hydro/Triadin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Triadin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:59299 UniProtKB/Swiss-Prot
NCBI Gene 59299 ENTREZGENE
PANTHER PTHR14106 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRIADIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Asp-B-Hydro_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trdn PhenoGen
RatGTEx ENSRNOG00000012609 RatGTEx
UniProt A0A0G2JU95_RAT UniProtKB/TrEMBL
  A0A1B0GWK5_RAT UniProtKB/TrEMBL
  A0A8L2RBI2_RAT UniProtKB/TrEMBL
  A6JUQ9 ENTREZGENE, UniProtKB/TrEMBL
  A6JUR0_RAT UniProtKB/TrEMBL
  A6JUR1_RAT UniProtKB/TrEMBL
  E9PTN7 ENTREZGENE
  F1LY11_RAT UniProtKB/TrEMBL
  Q5DVI6 ENTREZGENE
  Q5DVI7 ENTREZGENE
  Q9JKZ5 ENTREZGENE
  Q9JKZ6 ENTREZGENE
  Q9QX75 ENTREZGENE
  Q9QX76 ENTREZGENE
  TRDN_RAT UniProtKB/Swiss-Prot
UniProt Secondary E9PTN7 UniProtKB/Swiss-Prot
  Q5DVI6 UniProtKB/Swiss-Prot
  Q5DVI7 UniProtKB/Swiss-Prot
  Q9JKZ5 UniProtKB/Swiss-Prot
  Q9JKZ6 UniProtKB/Swiss-Prot
  Q9QX76 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Trdn  triadin    triadin 1  Name updated 1299863 APPROVED
2002-08-07 Trdn  triadin 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in adult rat skeletal muscle and also in rat embryo skeletal muscle 634424