Ryr1 (ryanodine receptor 1) - Rat Genome Database

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Gene: Ryr1 (ryanodine receptor 1) Rattus norvegicus
Analyze
Symbol: Ryr1
Name: ryanodine receptor 1
RGD ID: 1586637
Description: Enables ryanodine-sensitive calcium-release channel activity. Involved in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; response to estradiol; and response to purine-containing compound. Located in sarcolemma; sarcoplasmic reticulum membrane; and terminal cisterna. Is extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC686059; LOW QUALITY PROTEIN: ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like; ryanodine receptor 1-like, skeletal muscle; RYR-1; Ryr1l; similar to ryanodine receptor 1 (skeletal); skeletal muscle calcium release channel; skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; type 1 ryanodine receptor
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2184,292,578 - 84,423,799 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl184,292,578 - 84,423,812 (-)Ensembl
Rnor_6.0187,959,596 - 88,066,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl187,959,712 - 88,066,101 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,135,622 - 89,241,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,116,098 - 84,254,503 (-)NCBIRGSC3.4rn4RGSC3.4
Celera178,682,691 - 78,812,242 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
ankyloglossia  (ISO)
Aortic Coarctation  (ISO)
arthrogryposis due to muscular dystrophy  (ISO)
arthrogryposis multiplex congenita  (ISO)
atrial heart septal defect  (ISO)
Axial Myopathy, Late-Onset  (ISO)
Bronchomalacia  (ISO)
cardiomyopathy  (ISO)
caudal regression syndrome  (ISO)
central core disease  (ISO)
centronuclear myopathy  (ISO)
clubfoot  (ISO)
congenital fiber-type disproportion  (ISO,ISS)
Congenital Hip Dislocation  (ISO)
congenital muscular dystrophy  (ISO)
congenital myasthenic syndrome  (ISO)
congenital myopathy  (ISO)
Congenital Neuromuscular Disease, with Uniform Type 1 Fiber  (ISO)
congenital structural myopathy  (ISO)
Developmental Disabilities  (ISO)
distal arthrogryposis  (ISO)
Dwarfism  (ISO)
Dyskinesias  (ISO)
dystonia  (ISO)
fetal akinesia deformation sequence syndrome  (ISO)
fetal akinesia deformation sequence syndrome 1  (ISO)
gastroesophageal reflux disease  (ISO)
genetic disease  (ISO)
glaucoma  (ISO)
Heart Block  (ISO)
Hereditary Motor Neuropathy with Myopathic Features  (ISO)
Hydrops Fetalis  (ISO)
isolated elevated serum creatine phosphokinase levels  (ISO)
King Denborough syndrome  (ISO,ISS)
learning disability  (ISO)
Malignant Fever  (ISO)
malignant hyperthermia  (ISO)
Malignant Hypothermia  (ISO)
Mitochondrial Progressive Myopathy with Congenital Cataract, Hearing Loss, and Developmental Delay  (ISO)
multiminicore disease  (ISO)
Muscle Hypotonia  (ISO)
Muscle Weakness  (ISO)
Myalgia  (ISO)
myopathy  (ISO)
Myotonia  (ISO)
neuromuscular disease  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
ocular motor apraxia, Cogan type  (ISO)
osteoporosis  (ISO)
panhypopituitarism  (ISO)
ptosis  (ISO)
renal cell carcinoma  (ISO)
Rhabdomyolysis  (ISO)
rigid spine muscular dystrophy 1  (ISO)
scoliosis  (ISO)
ventricular septal defect  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',3,3',6,6'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-chloro-m-cresol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
Ammothamnine  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
baclofen  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bicuculline  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
chlordecone  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chrysene  (ISO)
Cuprizon  (EXP)
dantrolene  (ISO)
DDE  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (EXP,ISO)
dextran sulfate  (ISO)
dimethylarsinic acid  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
ethanol  (ISO)
fenvalerate  (ISO)
flubendiamide  (ISO)
folic acid  (ISO)
graphite  (ISO)
halothane  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP)
pioglitazone  (ISO)
raloxifene  (ISO)
ryanodine  (ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
spermine  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tetracaine  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7515481   PMID:7556644   PMID:7621815   PMID:7832748   PMID:8943043   PMID:10427100   PMID:10444070   PMID:10444400   PMID:11206130   PMID:11590243   PMID:11694536   PMID:11741831  
PMID:11784029   PMID:12207911   PMID:12223488   PMID:12704193   PMID:12937085   PMID:12954602   PMID:14592808   PMID:15536090   PMID:16163667   PMID:16186498   PMID:17074386   PMID:18003898  
PMID:18076146   PMID:18676612   PMID:19009018   PMID:19056867   PMID:19120137   PMID:19198614   PMID:20089138   PMID:20112737   PMID:20218309   PMID:21524998   PMID:21781462   PMID:22355118  
PMID:22480578   PMID:23454728   PMID:23695157   PMID:23943510   PMID:24124188   PMID:24233561   PMID:24431430   PMID:26115329   PMID:27499186   PMID:28044347   PMID:32619649   PMID:32916280  


Genomics

Comparative Map Data
Ryr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2184,292,578 - 84,423,799 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl184,292,578 - 84,423,812 (-)Ensembl
Rnor_6.0187,959,596 - 88,066,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl187,959,712 - 88,066,101 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,135,622 - 89,241,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,116,098 - 84,254,503 (-)NCBIRGSC3.4rn4RGSC3.4
Celera178,682,691 - 78,812,242 (-)NCBICelera
Cytogenetic Map1q21NCBI
RYR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381938,433,691 - 38,587,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1938,433,691 - 38,595,273 (+)EnsemblGRCh38hg38GRCh38
GRCh371938,924,331 - 39,078,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,616,180 - 43,770,044 (+)NCBINCBI36hg18NCBI36
Build 341943,616,179 - 43,770,012NCBI
Celera1935,726,452 - 35,880,238 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1935,371,495 - 35,526,332 (+)NCBIHuRef
CHM1_11938,924,701 - 39,079,134 (+)NCBICHM1_1
Ryr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,702,765 - 28,824,599 (-)NCBIGRCm39mm39
GRCm39 Ensembl728,702,769 - 28,824,604 (-)Ensembl
GRCm38729,003,340 - 29,125,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,003,344 - 29,125,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,788,359 - 29,910,170 (-)NCBIGRCm37mm9NCBIm37
MGSCv36728,712,104 - 28,833,911 (-)NCBImm8
Celera723,565,768 - 23,695,212 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
Ryr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955468879,951 - 1,000,036 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955468879,807 - 1,000,118 (-)NCBIChiLan1.0ChiLan1.0
RYR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11944,099,196 - 44,256,470 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1944,106,036 - 44,256,327 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01935,527,466 - 35,685,446 (+)NCBIMhudiblu_PPA_v0panPan3
RYR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11114,461,350 - 114,579,577 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1114,461,348 - 114,579,493 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1113,865,988 - 113,983,252 (-)NCBI
ROS_Cfam_1.01115,063,307 - 115,181,223 (-)NCBI
ROS_Cfam_1.0 Ensembl1115,063,305 - 115,204,391 (-)Ensembl
UMICH_Zoey_3.11114,636,271 - 114,754,225 (-)NCBI
UNSW_CanFamBas_1.01114,253,994 - 114,371,830 (-)NCBI
UU_Cfam_GSD_1.01115,292,565 - 115,410,455 (-)NCBI
Ryr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934913,020,295 - 13,133,060 (+)NCBI
SpeTri2.0NW_0049368011,185,615 - 1,298,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1647,339,759 - 47,458,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,840,240 - 42,960,110 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q1.2NCBI
RYR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1633,080,443 - 33,234,478 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl633,080,758 - 33,213,788 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607311,024,332 - 11,181,890 (+)NCBIVero_WHO_p1.0
Ryr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462479411,888,211 - 12,004,457 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D1Got388  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,388,001 - 84,388,149 (+)MAPPERmRatBN7.2
Rnor_6.0188,030,428 - 88,030,575NCBIRnor6.0
Rnor_5.0189,205,586 - 89,205,733UniSTSRnor5.0
RGSC_v3.4184,218,566 - 84,218,713UniSTSRGSC3.4
Celera178,777,328 - 78,777,475UniSTS
Cytogenetic Map1q21UniSTS
RH130025  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,292,313 - 84,292,466 (+)MAPPERmRatBN7.2
Rnor_6.0187,959,332 - 87,959,484NCBIRnor6.0
Rnor_5.0189,135,358 - 89,135,510UniSTSRnor5.0
RGSC_v3.4184,115,836 - 84,115,988UniSTSRGSC3.4
Celera178,682,427 - 78,682,579UniSTS
RH 3.4 Map1841.0UniSTS
Cytogenetic Map1q21UniSTS
RH133862  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,292,598 - 84,293,015 (+)MAPPERmRatBN7.2
Rnor_6.0187,959,617 - 87,960,033NCBIRnor6.0
Rnor_5.0189,135,643 - 89,136,059UniSTSRnor5.0
RGSC_v3.4184,116,121 - 84,116,537UniSTSRGSC3.4
Celera178,682,712 - 78,683,128UniSTS
RH 3.4 Map1828.9UniSTS
Cytogenetic Map1q21UniSTS
AI528790  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,292,607 - 84,292,748 (+)MAPPERmRatBN7.2
Rnor_6.0187,959,626 - 87,959,766NCBIRnor6.0
Rnor_5.0189,135,652 - 89,135,792UniSTSRnor5.0
RGSC_v3.4184,116,130 - 84,116,270UniSTSRGSC3.4
Celera178,682,721 - 78,682,861UniSTS
Cytogenetic Map1q21UniSTS
AW534727  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,360,847 - 84,361,386 (+)MAPPERmRatBN7.2
Rnor_6.0188,003,266 - 88,003,804NCBIRnor6.0
Rnor_5.0189,178,424 - 89,178,962UniSTSRnor5.0
RGSC_v3.4184,190,303 - 84,190,841UniSTSRGSC3.4
Celera178,750,182 - 78,750,720UniSTS
RH 3.4 Map1839.9UniSTS
Cytogenetic Map1q21UniSTS
AU049008  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2184,374,014 - 84,375,397 (+)MAPPERmRatBN7.2
Rnor_6.0188,016,436 - 88,017,818NCBIRnor6.0
Rnor_5.0189,191,594 - 89,192,976UniSTSRnor5.0
RGSC_v3.4184,203,476 - 84,204,858UniSTSRGSC3.4
Celera178,763,348 - 78,764,730UniSTS
Cytogenetic Map1q21UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:37
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000027893
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 11 4 8
Low 3 12 40 24 19 24 54 35 41 7
Below cutoff 31 17 17 17 20

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027893   ⟹   ENSRNOP00000027893
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl184,292,578 - 84,423,812 (-)Ensembl
Rnor_6.0 Ensembl187,975,997 - 88,066,101 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079473   ⟹   ENSRNOP00000073446
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl184,292,578 - 84,423,812 (-)Ensembl
Rnor_6.0 Ensembl187,959,712 - 88,066,101 (-)Ensembl
RefSeq Acc Id: XM_039100851   ⟹   XP_038956779
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2184,292,578 - 84,423,799 (-)NCBI
RefSeq Acc Id: XM_039100852   ⟹   XP_038956780
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2184,292,578 - 84,423,799 (-)NCBI
RefSeq Acc Id: XM_039100853   ⟹   XP_038956781
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2184,292,578 - 84,423,799 (-)NCBI
RefSeq Acc Id: XM_039100854   ⟹   XP_038956782
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2184,292,578 - 84,423,799 (-)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000073446   ⟸   ENSRNOT00000079473
RefSeq Acc Id: ENSRNOP00000027893   ⟸   ENSRNOT00000027893
RefSeq Acc Id: XP_038956782   ⟸   XM_039100854
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038956780   ⟸   XM_039100852
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038956781   ⟸   XM_039100853
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038956779   ⟸   XM_039100851
- Peptide Label: isoform X1
Protein Domains
B30.2/SPRY   EF-hand   MIR

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1586637 AgrOrtholog
BioCyc Gene G2FUF-60201 BioCyc
Ensembl Genes ENSRNOG00000020557 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000027893 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073446 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027893 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000079473 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  Ins145_P3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc-dom UniProtKB/Swiss-Prot
  RIH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryan_recept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanodine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanrecept_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY1_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY2_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY3_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 114207 ENTREZGENE
PANTHER PTHR13715:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc UniProtKB/Swiss-Prot
  RR_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYDR_ITPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB RYR1 RGD
PhenoGen Ryr1 PhenoGen
PRINTS RYANODINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K5J1_RAT UniProtKB/TrEMBL
  F1LMY4 ENTREZGENE, UniProtKB/Swiss-Prot
  V9GZ83_RAT UniProtKB/TrEMBL
UniProt Secondary O35208 UniProtKB/Swiss-Prot
  Q9R1G1 UniProtKB/Swiss-Prot
  Q9R272 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Ryr1  ryanodine receptor 1  Ryr1  ryanodine receptor 1 (skeletal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-15 Ryr1  ryanodine receptor 1 (skeletal)  Ryr1l  ryanodine receptor 1-like  Data Merged 737654 APPROVED
2008-09-18 Ryr1  ryanodine receptor 1 (skeletal)  Ryr1  ryanodine receptor 1, skeletal muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Ryr1l  ryanodine receptor 1-like  Ryr1l  ryanodine receptor 1-like, skeletal muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Ryr1l  ryanodine receptor 1-like, skeletal muscle  Ryr1  ryanodine receptor 1, skeletal muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Ryr1  ryanodine receptor 1, skeletal muscle  LOC686059  similar to ryanodine receptor 1 (skeletal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC686059  similar to ryanodine receptor 1 (skeletal)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Ryr1  ryanodine receptor 1, skeletal muscle    ryanodine receptor 1 (skeletal)  Name updated 1299863 APPROVED
2002-08-07 Ryr1  ryanodine receptor 1 (skeletal)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation channel activated by cyclic ADP-ribose in skeletal muscle 724691