Strain: SD-Abcc2em1Sage

Symbol: SD-Abcc2em1Sage
Strain: SD-Abcc2em1
Substrain: Sage
Ontology ID: RS:0004436
Alleles: Abcc2em1Sage
Also known as: TGRS4340; SD- Abcc2 tm1sage; Mrp2 Knockout Rat
Type: mutant
Source: Horizon Discovery
Origin: This ZFN model contains biallelic 726 bp deletion within Abcc2 gene. Animals exhibit decreased transport of endogenous glutathione and hyperbilirubinemia. The homozygous knockout rats display total loss of protein via Western blot.
Genetic Status: Homozygous
Last Known Status: Live Animals (as of 2017-05-17)
Research Usage Efflux Transporter
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01263,554,426 - 263,612,556RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01270,999,832 - 271,057,750RGD_MAPPER_PIPELINERnor5.0

Experimental Data Annotations
References - curated


Additional Information

More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 12904685
Created: 2017-05-17
Species: Rattus norvegicus
Last Modified: 2017-05-17
Status: ACTIVE