Gene: Cdkn1b (cyclin-dependent kinase inhibitor 1B) Rattus norvegicus
Symbol: Cdkn1b
Name: cyclin-dependent kinase inhibitor 1B
Description: ENCODES a protein that exhibits chaperone binding; Hsp70 protein binding; protein complex binding; INVOLVED IN cell death; negative regulation of cell proliferation; negative regulation of cyclin-dependent protein serine/threonine kinase activity; PARTICIPATES IN forkhead class A signaling pathway; G1/S transition pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Acute Kidney Injury; Brain Injuries; Diabetic Nephropathies; FOUND IN cytoplasm; nucleus; protein complex; INTERACTS WITH (+)-pilocarpine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (Z)-3-butylidenephthalide
Type: protein-coding
Also known as: Cdki1b; CDKN4; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; cyclin-dependent kinase inhibitor p27/Kip1; Kip1; p27; P27KIP1
Homo sapiens (human) : CDKN1B (cyclin dependent kinase inhibitor 1B)  HGNC  AGR
Mus musculus (house mouse) : Cdkn1b (cyclin-dependent kinase inhibitor 1B)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Cdkn1b (cyclin dependent kinase inhibitor 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : CDKN1B (cyclin dependent kinase inhibitor 1B)
Canis lupus familiaris (dog) : CDKN1B (cyclin dependent kinase inhibitor 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdkn1b (cyclin dependent kinase inhibitor 1B)
more info ...
Allele / Splice: Cdkn1bwe  
Genetic Models: SD-Cdkn1bwe
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04168,689,043 - 168,694,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04232,962,218 - 232,967,323 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44171,841,705 - 171,846,506 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14172,086,631 - 172,091,508 (+)NCBI
Celera4156,357,827 - 156,362,628 (+)NCBICelera
Cytogenetic Map4q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cdkn1b
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69062
Created: 2001-11-08
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE