Gene: Plce1 (phospholipase C, epsilon 1) Rattus norvegicus
Symbol: Plce1
Name: phospholipase C, epsilon 1
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; Ras GTPase binding; enzyme binding (ortholog); INVOLVED IN G-protein coupled receptor signaling pathway; Ras protein signal transduction; activation of MAPK activity (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Esophageal Squamous Cell Carcinoma (ortholog); Mesangial Sclerosis, Diffuse (ortholog); FOUND IN cytoplasm; cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1; phosphoinositide phospholipase C-epsilon-1; phosphoinositide-specific phospholipase C epsilon-1; phospholipase C epsilon; phospholipase C epsilon 1; phospholipase C, epsilon; phospholipase C-epsilon-1; PLC-epsilon-1; Plce
Homo sapiens (human) : PLCE1 (phospholipase C epsilon 1)  HGNC  Alliance
Mus musculus (house mouse) : Plce1 (phospholipase C, epsilon 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plce1 (phospholipase C epsilon 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCE1 (phospholipase C epsilon 1)
Canis lupus familiaris (dog) : PLCE1 (phospholipase C epsilon 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plce1 (phospholipase C epsilon 1)
more info ...
Allele / Splice: Plce1Tn(sb-T2/Bart3)2.146Mcwi  
Genetic Models: F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01257,156,023 - 257,465,440 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01264,652,842 - 264,956,664 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41242,794,858 - 243,103,437 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11242,891,416 - 243,199,995 (+)NCBI
Celera1233,337,820 - 233,642,815 (+)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Plce1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69424
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE