Strain Report - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Strain: LE-Grin2bem1Mcwi

Symbol: LE-Grin2bem1Mcwi
Strain: LE-Grin2bem1
Substrain: Mcwi
RGD ID: 14394515
Citation ID: RRID:RGD_14394515
Ontology ID: RS:0004694
Alleles: Grin2bem1Mcwi
Type: mutant
Source: Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center
Origin: CRISPR/Cas9 system was used to introduce a mutation in the Grin2b gene of Crl:LE rat embryos. The resulting mutation is deletion of exon 3.
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2021-11-03)
Research Usage Autism, Developmental delay, Intellectual disability, Epilepsy (from SFARI GENE)
Genotyping Protocol Download Genotyping Protocol
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24168,580,824 - 169,044,110RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04169,541,620 - 170,000,216RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04233,806,406 - 234,260,360RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44172,721,895 - 173,183,187RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Data registered by Dr. Melinda Dwinell’s group Personal communication between Dr. Melinda Dwinell’s group and the RGD curators


Additional Information