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Strain: FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-

Symbol: FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-
Strain: FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1-/Rab38em1-
Substrain: Mcwi
Full Name: FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi-
RGD ID: 5688087
Citation ID: RRID:RGD_5688087
Ontology ID: RS:0003152
Alleles: Rab38em1Mcwi
Previously known as: FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi-/-; FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi/1Mcwi; FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi/1Mcwi; FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi-/Rab38em3Mcwi-; FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-
Type: mutant
Source: PhysGen Knockouts
Origin: ZFN mutant founders were backcrossed with FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi to get heterozygous offspring which were intercrossed and offspring maintained as homozygous and heterozygous breeders.
Genetic Status: Homozygous
Last Known Status: Cryopreserved Sperm (as of 2021-11-03)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21142,182,566 - 142,262,923RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01152,072,716 - 152,153,449RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01158,385,888 - 158,466,621RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41144,783,919 - 144,864,573RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View
Albuminuria  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. Rab38 modulates proteinuria in model of hypertension-associated renal disease. Rangel-Filho A, etal., J Am Soc Nephrol. 2013 Feb;24(2):283-92. doi: 10.1681/ASN.2012090927. Epub 2013 Jan 4.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-31 FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-  FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi-  FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-  FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi-  Name/Symbol updated 68913 APPROVED
2012-02-17 FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/-  FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi-  FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi-/-  FHH.BN-(Rab38)/Mcwi-Rab38em1Mcwi-/Rab38em1Mcwi-  Name/Symbol updated 68913 APPROVED