Gene: Ednrb (endothelin receptor type B) Rattus norvegicus
Symbol: Ednrb
Name: endothelin receptor type B
Description: ENCODES a protein that exhibits endothelin receptor activity; type 1 angiotensin receptor binding; peptide hormone binding (ortholog); INVOLVED IN aging; cellular response to lipopolysaccharide; cGMP-mediated signaling; PARTICIPATES IN calcium/calmodulin dependent kinase signaling pathway; endothelin signaling pathway; inflammatory response pathway; ASSOCIATED WITH abnormal coat/hair pigmentation; abnormal enteric ganglia morphology; abnormal spleen B cell follicle morphology; ASSOCIATED WITH Aganglionosis, Total Intestinal; asthma; Hearing Loss, Sensorineural; FOUND IN membrane; membrane raft; nuclear membrane; INTERACTS WITH (R)-noradrenaline; (S)-colchicine; (S)-nicotine
Type: protein-coding
Also known as: Ednra; endothelin B receptor; endothelin receptor; endothelin receptor non-selective type; endothelin-B receptor; ET-B; ET-BR; Etb
Homo sapiens (human) : EDNRB (endothelin receptor type B)  HGNC  Alliance
Mus musculus (house mouse) : Ednrb (endothelin receptor type B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ednrb (endothelin receptor type B)
Pan paniscus (bonobo/pygmy chimpanzee) : EDNRB (endothelin receptor type B)
Canis lupus familiaris (dog) : EDNRB (endothelin receptor type B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ednrb (endothelin receptor type B)
more info ...
Allele / Splice: Ednrbsl  
Genetic Models: Sl LE/Hkv.AR-Ednrbsl F344.AR-Ednrbsl/Hkv AR-Ednrbsl/Hkv LE.AR-Ednrbsl/Okkm AR-Ednrbsl/Okkm
Is Marker For: Strains:   DA   Sl   LE.AR-Ednrbsl/Okkm   AR-Ednrbsl/Okkm   AR-Ednrbsl/Hkv   LE/Hkv.AR-Ednrbsl   F344.AR-Ednrbsl/Hkv  
QTLs:   Scl1   BpQTLcluster12   Bp126   Gluco31  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01588,004,775 - 88,036,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01591,500,400 - 91,531,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41587,893,141 - 87,898,700 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11587,908,924 - 87,914,471 (-)NCBI
Celera1579,772,740 - 79,801,760 (-)NCBICelera
Cytogenetic Map15q22NCBI
RH 3.4 Map15496.21RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ednrb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2536
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE