Ednrb (endothelin receptor type B) - Rat Genome Database

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Gene: Ednrb (endothelin receptor type B) Ictidomys tridecemlineatus
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Symbol: Ednrb
Name: endothelin receptor type B
RGD ID: 12638942
Description: ENCODES a protein that exhibits endothelin receptor activity (ortholog); peptide hormone binding (ortholog); type 1 angiotensin receptor binding (ortholog); INVOLVED IN aging (ortholog); calcium-mediated signaling (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase signaling pathway; endothelin signaling pathway; inflammatory response pathway; ASSOCIATED WITH ABCD syndrome (ortholog); asthma (ortholog); autosomal recessive nonsyndromic deafness (ortholog); FOUND IN membrane (ortholog); membrane raft (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: endothelin B receptor; endothelin receptor type B, transcript variant X1; endothelin receptor type B, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945128,029,566 - 128,061,207 (+)NCBI
SpeTri2.0NW_0049365113,446,864 - 3,478,434 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
calcium-mediated signaling  (ISO)
cellular response to lipopolysaccharide  (ISO)
cGMP-mediated signaling  (ISO)
developmental pigmentation  (ISO)
endothelin receptor signaling pathway  (ISO)
enteric nervous system development  (ISO)
enteric smooth muscle cell differentiation  (ISO)
epithelial fluid transport  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
macrophage chemotaxis  (ISO)
melanocyte differentiation  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cellular protein metabolic process  (ISO)
negative regulation of neuron maturation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
neural crest cell migration  (ISO)
peripheral nervous system development  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (ISO)
pigmentation  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of penile erection  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of renal sodium excretion  (ISO)
positive regulation of urine volume  (ISO)
posterior midgut development  (ISO)
regulation of blood pressure  (ISO)
regulation of epithelial cell proliferation  (ISO)
regulation of fever generation  (ISO)
regulation of pH  (ISO)
regulation of sensory perception of pain  (ISO)
response to endothelin  (ISO)
response to lipopolysaccharide  (ISO)
response to organic cyclic compound  (ISO)
response to pain  (ISO)
sensory perception of pain  (ISO)
vasoconstriction  (ISO)
vasodilation  (ISO)
vein smooth muscle contraction  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Ednrb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945128,029,566 - 128,061,207 (+)NCBI
SpeTri2.0NW_0049365113,446,864 - 3,478,434 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDNRB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1377,895,481 - 77,975,529 (-)EnsemblGRCh38hg38GRCh38
GRCh381377,895,481 - 77,975,527 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371378,469,616 - 78,549,662 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361377,367,617 - 77,447,665 (-)NCBINCBI36hg18NCBI36
Build 341377,368,543 - 77,390,935NCBI
Celera1359,367,540 - 59,390,895 (-)NCBI
Cytogenetic Map13q22.3NCBI
HuRef1359,168,348 - 59,248,390 (-)NCBIHuRef
CHM1_11378,436,966 - 78,516,998 (-)NCBICHM1_1
Ednrb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914104,052,051 - 104,083,248 (-)NCBIGRCm39mm39
GRCm39 Ensembl14104,052,061 - 104,081,838 (-)Ensembl
GRCm3814103,814,615 - 103,844,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14103,814,625 - 103,844,402 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714104,213,842 - 104,243,390 (-)NCBIGRCm37mm9NCBIm37
MGSCv3614102,700,305 - 102,729,375 (-)NCBImm8
Celera14102,434,540 - 102,464,042 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1453.05NCBI
Ednrb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21580,640,839 - 80,672,115 (-)NCBI
Rnor_6.0 Ensembl1588,006,977 - 88,036,354 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01588,004,775 - 88,036,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01591,500,400 - 91,531,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41587,893,141 - 87,898,700 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11587,908,924 - 87,914,471 (-)NCBI
Celera1579,772,740 - 79,801,760 (-)NCBICelera
RH 3.4 Map15496.21RGD
Cytogenetic Map15q22NCBI
Ednrb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540429,394,164 - 29,425,358 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540429,394,253 - 29,425,358 (+)NCBIChiLan1.0ChiLan1.0
EDNRB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11378,153,026 - 78,177,281 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1378,153,020 - 78,177,286 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01359,112,349 - 59,136,615 (-)NCBIMhudiblu_PPA_v0panPan3
EDNRB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12231,415,324 - 31,438,772 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2231,417,308 - 31,437,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2231,277,699 - 31,297,545 (-)NCBI
ROS_Cfam_1.02231,733,123 - 31,756,544 (-)NCBI
UMICH_Zoey_3.12231,396,562 - 31,416,398 (-)NCBI
UNSW_CanFamBas_1.02231,434,803 - 31,454,631 (-)NCBI
UU_Cfam_GSD_1.02231,507,052 - 31,526,893 (-)NCBI
EDNRB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1150,072,554 - 50,102,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11150,073,300 - 50,102,879 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21154,689,465 - 54,718,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EDNRB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1356,969,493 - 56,993,719 (-)NCBI
ChlSab1.1 Ensembl356,969,101 - 56,992,731 (-)Ensembl
Vero_WHO_p1.0NW_02366604613,190,167 - 13,214,545 (-)NCBI
Ednrb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475122,459,613 - 22,491,409 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005324792   ⟹   XP_005324849
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404945128,029,566 - 128,061,207 (+)NCBI
SpeTri2.0NW_0049365113,446,864 - 3,478,434 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726077   ⟹   XP_021581752
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365113,447,670 - 3,478,434 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005324849 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3292870 (Get FASTA)   NCBI Sequence Viewer  
  KAG3292871 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005324849   ⟸   XM_005324792
- UniProtKB: I3MD81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021581752   ⟸   XM_021726077
- Sequence:
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009258 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000008308 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009259 UniProtKB/TrEMBL
InterPro Endthln_rcpt UniProtKB/TrEMBL
  ETB_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
NCBI Gene Ednrb ENTREZGENE
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS ENDOTHELINBR UniProtKB/TrEMBL
  ENDOTHELINR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
UniProt I3MD81 ENTREZGENE, UniProtKB/TrEMBL