Eae19 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Eae19 (Experimental allergic encephalomyelitis QTL 19) Rattus norvegicus

Symbol: Eae19
Name: Experimental allergic encephalomyelitis QTL 19
RGD ID: 1581555
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: experimental autoimmune encephalomyelitis severity score   (CMO:0001419)    
LOD Score: 4.7
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01583,947,714 - 98,027,710RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01587,456,591 - 101,499,751RGDRnor5.0
RGSC_v3.41583,349,371 - 97,700,727RGDRGSC3.4
RGSC_v3.11583,365,152 - 97,716,507RGD
Cross Type: Not Available
Strains Crossed: DA PVG.1AV1 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
DA  (IEA)
PVG.1AV1  (IEA)

References

References - curated
1. Sheng JR, etal., Genetics 2005 May;170(1):283-9. Epub 2005 Feb 16.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2536Ednrbendothelin receptor type B158800477588036354Rat
620074Pou4f1POU class 4 homeobox 1158861825588622712Rat
1305102Scelsciellin158768919087820731Rat
1308858Slitrk1SLIT and NTRK-like family, member 1159330338293307420Rat
1306550Slitrk6SLIT and NTRK-like family, member 6159550763295514259Rat
1308626Slain1SLAIN motif family, member 1158786283287906472Rat
1311472Spry2sprouty RTK signaling antagonist 2159017276990177823Rat
1312048Mycbp2MYC binding protein 2159367806293901556Rat
1312048Mycbp2MYC binding protein 2158740547287450812Rat
1309421Kctd12potassium channel tetramerization domain containing 12158738463287390627Rat
1305660Fbxl3F-box and leucine-rich repeat protein 3159364730793667395Rat
1308297Rbm26RNA binding motif protein 26158926268389339323Rat
1310957Slitrk5SLIT and NTRK-like family, member 5159681790796826760Rat
1309204Klf12Kruppel-like factor 12158431698684748549Rat
1306965Cln5CLN5, intracellular trafficking protein159363481593644146Rat
1564706Obi1ORC ubiquitin ligase 1158863208988670325Rat
1561196Uchl3ubiquitin C-terminal hydrolase L3158615362486198127Rat
1562819RGD1562819similar to Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (P18)158661019986610641Rat
1309716Ndfip2Nedd4 family interacting protein 2158940742689458983Rat
1302984Lmo7LIM domain 7158624291186458512Rat
1560745Commd6COMM domain containing 6158613609686142672Rat
1559833RGD1559833similar to 60S ribosomal protein L5159667056996671884Rat
1561609Tbc1d4TBC1 domain family, member 4158592797886105829Rat
1565438RGD1565438similar to ATP synthase, H+ transporting, mitochondrial Fo complex, subunit g158934799389348449Rat
1565615Trim52tripartite motif-containing 52159036451790388295Rat
1560797RGD1560797similar to glyceraldehyde-3-phosphate dehydrogenase158508742285112505Rat
1563454Acod1aconitate decarboxylase 1159361296893622322Rat
1593227LOC364462similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M)159064154090648166Rat
1592125LOC692047hypothetical protein LOC692047159768740197688523Rat
1592127LOC692045similar to eukaryotic translation initiation factor 4A2159590990595910562Rat
1592131LOC692041hypothetical protein LOC692041158972883089729199Rat
1592132LOC692040similar to ribosomal protein S13158966587089666356Rat
1592134LOC692038similar to ribosomal protein S11158934502989355717Rat
1592135LOC692037similar to ribosomal protein S18158869192588692627Rat
1592138LOC692034similar to Aspartate aminotransferase, mitochondrial precursor (Transaminase A) (Glutamate oxaloacetate transaminase 2)158649708086498358Rat
1592139LOC692033similar to ribosomal protein L10a158498660685028467Rat
1586012LOC501543similar to basic leucine zipper and W2 domains 1159220837392216081Rat
1592109LOC290453hypothetical LOC290453158911467289116568Rat
1592110LOC290444similar to eukaryotic translation initiation factor 3, subunit 12158660091286601539Rat
2319369LOC100361805WD repeat domain 12159563819695644732Rat
2319992LOC100364974hypothetical LOC100364974158957747789578094Rat
2319521LOC100361753apolipoprotein O-like159456295094563993Rat
2323417LOC100363223hypothetical LOC100363223158989830089899025Rat
2320734RGD2320734cytochrome b-c1 complex subunit 9-like158612318186123498Rat
2323017LOC100363428PCNA-associated factor-like159211460992115676Rat
2323174LOC100363369hypothetical LOC100363369159188479091885729Rat
2324281Selenok-ps4selenoprotein K, pseudogene 4158529180485292538Rat
2323641LOC100359553heterogeneous nuclear ribonucleoprotein A1-like159532279095323886Rat
2323849LOC100359444heterogeneous nuclear ribonucleoprotein D-like159433863094359947Rat
2323955LOC100362823hypothetical LOC100362823158620424286205466Rat
6485145LOC100912914actin, cytoplasmic 2-like159555073195559457Rat
6498975LOC10091037940S ribosomal protein S13-like158966014289660628Rat
6500878LOC100909907uncharacterized LOC100909907158765997287667127Rat
7501055LOC102553928uncharacterized LOC102553928159206709192078490Rat
7502353LOC102546379uncharacterized LOC102546379158726278587264293Rat
7531625LOC102549194uncharacterized LOC102549194158976658689767747Rat
7513265LOC102553620uncharacterized LOC102553620159154695191548273Rat
7536491LOC102554612MLV-related proviral Env polyprotein-like159292538592927102Rat
7632669LOC102546300uncharacterized LOC102546300158721585187222414Rat
7653320LOC102553927uncharacterized LOC102553927158391471283990016Rat
7577763LOC102556284uncharacterized LOC102556284158701690687090954Rat
7625858LOC102550655uncharacterized LOC102550655158905474389062753Rat
7615992LOC102550034uncharacterized LOC102550034158762223387625434Rat
7590644LOC102554519glyceraldehyde-3-phosphate dehydrogenase-like159267778192678706Rat
7560548LOC102546988uncharacterized LOC102546988159736878697377559Rat
7551641LOC10255613260S ribosomal protein L21-like159600592096006411Rat
7554898LOC102551509uncharacterized LOC102551509158977499189781041Rat
7751243LOC102550182uncharacterized LOC102550182158803664388060008Rat
7752722LOC102556356uncharacterized LOC102556356159660669996633652Rat
7686929LOC102555054uncharacterized LOC102555054158474987084785357Rat
7716236LOC102556074uncharacterized LOC102556074159587661995884963Rat
7666955LOC102550758uncharacterized LOC102550758158879904989071484Rat
7742907LOC102550315uncharacterized LOC102550315158833952888341022Rat
7747880LOC102556470uncharacterized LOC102556470159655356296603397Rat
7679581LOC102555382uncharacterized LOC102555382158552426185530368Rat
9187193LOC103693842ferritin light chain 1 pseudogene159241752892417962Rat
9158814LOC103693773uncharacterized LOC103693773159671742396736761Rat
9194298LOC103693766uncharacterized LOC103693766158432841384353539Rat
9334918LOC103693881uncharacterized LOC103693881158438015584386355Rat
9360512LOC103693887uncharacterized LOC103693887159641108796511565Rat
9364271LOC103693771uncharacterized LOC103693771159029498490357086Rat
9388800LOC103693772uncharacterized LOC103693772159523020795284872Rat
11362114LOC108352953glyceraldehyde-3-phosphate dehydrogenase pseudogene158512651285126988Rat
11362115LOC108352964uncharacterized LOC108352964159069379290712502Rat
11362124LOC108352969uncharacterized LOC108352969159513250395149965Rat
11455629LOC108352970uncharacterized LOC108352970159616499896220806Rat
11360552LOC108353048uncharacterized LOC108353048159270320892705244Rat
11361310LOC10835304560S ribosomal protein L29 pseudogene158783769187838176Rat
11452914LOC108352963uncharacterized LOC108352963158917164689176296Rat
11427239LOC108352956uncharacterized LOC108352956158696370686968620Rat
11376868LOC108352955uncharacterized LOC108352955158518280185192808Rat
11410085LOC108352959uncharacterized LOC108352959158755345587561139Rat
11402272LOC108353046protein transport protein Sec61 subunit gamma pseudogene159047959790479983Rat
11392754LOC10835296140S ribosomal protein S18 pseudogene158868821988692683Rat
11393005LOC108353047uncharacterized LOC108353047159180682091819283Rat
11393907LOC108352967cytochrome c, somatic pseudogene159383021593831903Rat
11503401LOC108353011MLV-related proviral Env polyprotein-like159154303191546635Rat
11481983LOC108352968uncharacterized LOC108352968159518340595190765Rat
11497845LOC108348240glyceraldehyde-3-phosphate dehydrogenase-like159211570392116609Rat
11498208LOC108352954uncharacterized LOC108352954158512737085156092Rat
11512925LOC108352966uncharacterized LOC108352966159362539993627575Rat
11513546LOC108352971uncharacterized LOC108352971159723647097420593Rat
11494307LOC108352960uncharacterized LOC108352960158768401287691897Rat
11494316LOC108353049endogenous retrovirus group K member 9 Pol protein-like159292178992923180Rat
11485972LOC108352962uncharacterized LOC108352962158852348488614286Rat
11486602LOC108352957E3 ubiquitin-protein ligase MYCBP2-like158745413487540810Rat
11518120LOC108352952uncharacterized LOC108352952158435844884367845Rat
11487989LOC108352958cytochrome c, somatic pseudogene158746182187463509Rat
11489075LOC108352965endogenous retrovirus group K member 21 Env polyprotein-like159207850192086962Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10504D15Mco2226158800443888004663Ratregion
10504D15Mco2226158800420688004663Ratregion
34357D15Mgh4143158394771483947819Ratregion
34409D15Mgh9142158964068489640841Ratregion
37584D15Rat71190158600183486002030Ratregion
40106D15Rat102153159802755898027710Ratregion
40312D15Rat100161158977373389773860Ratregion
43058D15Rat154229159005092490051156Ratregion
42408D15Rat166144158548043785480579Ratregion
43400D15Got96132159717833997178470Ratregion
60119D15Got78207158518728085187486Ratregion
60120D15Got80140158487146984871608Ratregion
45283D15Got79171159153543091535600Ratregion
45284D15Got81277159224049892240780Ratregion
45285D15Got82165159161745491617618Ratregion
45286D15Got83247159416116094161406Ratregion
45287D15Got8679159784941997849497Ratregion
45288D15Got93144159645444196454586Ratregion
45289D15Got84148159679189796792044Ratregion
45292D15Got89160159656679796566956Ratregion
625772D2Got189217158971163689711852Ratregion
62449D15Uia3168158794178687941952Ratregion
66633D15Mco3190158800940588009579Ratregion
1629313D15Wox13248158801200088012247Ratregion
1641365D15Got214112158573418185734292Ratregion
1639818D15Got216165158800456388004725Ratregion
1639818D15Got216165158800433188004725Ratregion
1640394D15Ulb3284158801041788010700Ratregion
1638133D15Got221176158600191486002084Ratregion
1634535D15Got226138158477311884773255Ratregion
5035855PMC24270P1212158800731488007525Ratregion
5038704AU01771996158928433089284425Ratregion
5036675AU048835247159308177993082025Ratregion
5036967AU049781228159124373991243966Ratregion
5033871RH140431144159681559696815739Ratregion
5026352RH131875203159364938293649584Ratregion
5034357RH44769264159017739290177655Ratregion
5029225RH143991149159017323490173382Ratregion
5034750BI276836229159364347793643705Ratregion
5035136BQ201059196159017378590173980Ratregion
5034850AA850154143158613600986136151Ratregion
5035274AI102336158159382454793824704Ratregion
5035274AI102336158158745615387456310Ratregion
5033647RH139590209158493377684933984Ratregion
5031077BE109270150158861590088616049Ratregion
5056333RH144318134159364589593646028Ratregion
5059682BE097625158158945820689458363Ratregion
5056563RH144451101159683108496831184Ratregion
5055613RH143902161159367875593678915Ratregion
5059874BF400055184159016898590169168Ratregion
5057804BI277150154158612309386123245Ratregion
5051082RH134429217159364776393647979Ratregion
5050372RH134018181158855164788551827Ratregion
5052945RH142365180158945870889458887Ratregion
5054239RH143110115158861818488618298Ratregion
5040944RH128573194159074667990746872Ratregion
5046146RH131584219158645824886458466Ratregion
5045432RH131174184159017217990172362Ratregion
5045450RH131185190158926929489269483Ratregion
5049588RH133567200158911635789116555Ratregion
5039572RH127782200159636347996363677Ratregion
5043064RH129810203158799960887999810Ratregion
7192428Pou4f1835158862158688622420Ratregion
5073844RH137671145159330414593304289Ratregion
5076802RH139387153158955022889550380Ratregion
5076102RH138980120159315281693152935Ratregion
5076842RH139410247158926276889263014Ratregion
5078452RH140351157159366844993668605Ratregion
5078212RH140209180158800482988005008Ratregion
5078612RH14044498158493408984934186Ratregion
5079050RH140705181158800550988005690Ratregion
5066820AU048131228158877002088770248Ratregion
5068088AU047355203159226869392268895Ratregion
5069500AU046455331158895104988951377Ratregion
5060260BG378310197158782030187820499Ratregion
5065544BE109259161158928922189289381Ratregion
5060938BF401438250159660679496607043Ratregion
5060076BF388427151158475222184752371Ratregion
5065224BE121229179159356839493568572Ratregion
5065514BE109190164159366811893668281Ratregion
5062650BF403686169158448452284484690Ratregion
5062708BF403952151159672568096725830Ratregion
5065948BI298444170158435364684353936Ratregion
5066078BF41331992158641655286416643Ratregion
5066242PMC125354P1274158862049488620767Ratregion
5061354BF396296180158861666288616841Ratregion
5064824BF405158124159682636496826487Ratregion
5066560AU048285121158790327687903396Ratregion
5084088AI408351167158738470487384870Ratregion
5082519BE119601151158766017587660325Ratregion
5088054Pou4f178158862002788620104Ratregion
5083385AA818970180158803517988035358Ratregion
5084390AI101498196159657078996570984Ratregion
5081885BF415208181158945870989458889Ratregion
5084890AI009239220159365023393650452Ratregion
5088393AU048543289158464684084647128Ratregion
5085276BM390056201158616328486163484Ratregion
5084660AI178492187159364719693647382Ratregion
5086345BM386386216159367978093679995Ratregion
5081038RH141929180158738793587388114Ratregion
5086727AI008211192158642446586424656Ratregion
5503566D6S2838535158895948688960020Ratregion
5503770UniSTS:470675153158862046688620618Ratregion
5503873EDNRB-21429158801239688013824Ratregion
5503658UniSTS:465489164158862045588620618Ratregion
5504316D13S865E207159330396793304173Ratregion
5506511UniSTS:276144998158862147288622469Ratregion
5502784TBC1D4137158593624485936380Ratregion
5500561RH136003215158432117284321386Ratregion
5501872MARC_16477-16478:1019839220:10158930675189307434Ratregion
5501872MARC_16477-16478:1019839220:10158930675189306835Ratregion
5502527RH125194171159372343893723608Ratregion
Position Markers

Flank 1: (D15Mgh4)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01583,947,714 - 83,947,819NCBI
Rnor_5.01587,456,591 - 87,456,696UniSTS
RGSC_v3.41583,349,372 - 83,349,477UniSTS
RGSC_v3.41583,349,371 - 83,349,477RGD
RGSC_v3.11583,365,152 - 83,365,257RGD
Celera1575,545,830 - 75,545,935UniSTS
Cytogenetic Map4q34UniSTS
RH 3.4 Map15528.0UniSTS
RH 3.4 Map15528.0RGD
RH 2.0 Map15405.8RGD
SHRSP x BN Map1548.3298RGD
Peak: (D15Rat71)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01586,001,834 - 86,002,030NCBI
Rnor_5.01589,768,256 - 89,768,452UniSTS
RGSC_v3.41585,456,316 - 85,456,512UniSTS
RGSC_v3.41585,456,315 - 85,456,512RGD
RGSC_v3.11585,472,096 - 85,472,292RGD
Celera1577,523,991 - 77,524,187UniSTS
Cytogenetic Map15q21UniSTS
RH 3.4 Map15541.3UniSTS
RH 3.4 Map15541.3RGD
RH 2.0 Map15419.4RGD
SHRSP x BN Map1550.5798RGD
FHH x ACI Map1563.69RGD
Flank 2: (D15Rat102)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01598,027,558 - 98,027,710NCBI
Rnor_5.015101,499,599 - 101,499,751UniSTS
RGSC_v3.41597,700,575 - 97,700,727UniSTS
RGSC_v3.41597,700,574 - 97,700,727RGD
RGSC_v3.11597,716,355 - 97,716,507RGD
Celera1589,023,691 - 89,023,843UniSTS
Cytogenetic Map4q34UniSTS
RH 3.4 Map15619.29UniSTS
RH 3.4 Map15619.29RGD
RH 2.0 Map15556.3RGD
SHRSP x BN Map1558.5998RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151851391388036354Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1526381041106550657Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1526381041106550657Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1526381041106550657Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)153321910189640841Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)153321910189640841Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)153321910189640841Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154106809486068094Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1543097470106550657Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1561447766106447766Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)156259641099372139Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1562596410103164962Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1565520564110520564Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1575527634111246239Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1575761024109400896Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1581255292103165069Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1581255292109133904Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)1581255430103164962Rat
1581555Eae19Experimental allergic encephalomyelitis QTL 194.7nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)158394771498027710Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1583947714111246239Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1584050550111246239Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1584050550111246239Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1589640684106550657Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)1589640684106550657Rat
1581519Cm59Cardiac mass QTL 592.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1596777066104003672Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_map QTL region supported by analysis of congenic strains 1549617