Gene: Agtr1b (angiotensin II receptor, type 1b) Rattus norvegicus
Symbol: Agtr1b
Name: angiotensin II receptor, type 1b
Description: ENCODES a protein that exhibits angiotensin type II receptor activity (inferred); INVOLVED IN angiotensin-activated signaling pathway; cellular response to dexamethasone stimulus; G protein-coupled receptor signaling pathway; PARTICIPATES IN angiotensin III signaling pathway via AT1 receptor; angiotensin II signaling pathway; angiotensin II signaling pathway via AT1 receptor; ASSOCIATED WITH Cardiomegaly; hypertension; Postoperative Cognitive Dysfunction; FOUND IN integral component of membrane (inferred); plasma membrane (inferred); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Agtr1; Angiotensin II receptor, type 1 (AT1B); angiotensin II receptor, type-1; angiotensin II type-1 receptor; angiotensin II type-1B receptor; angiotensin receptor 1; angiotensin receptor 1b; AT1; At1b; AT3; AT1R; type-1B angiotensin II receptor
Allele / Splice: Agtr1bm1Mcwi  
Genetic Models: FHH-Agtr1bm1Mcwi
Is Marker For: Strains:   SHR   SD-Tg(Ren2)27   SS.MNS-(D2Mit6-Adh1)/Ayd  
QTLs:   Bp36   Bp99  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02105,149,020 - 105,224,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02124,879,262 - 124,954,378 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,503,269 - 105,602,591 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12105,448,230 - 105,547,520 (-)NCBI
Celera298,214,526 - 98,286,355 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Protein Structures

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agtr1b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2071
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE