(R,R)-tramadol multiple interactions EXP 6480464 Ethanol promotes the reaction [Tramadol results in increased expression of SPP1 protein], Tramadol promotes the reaction [Ethanol results in increased expression of SPP1 protein] CTD PMID:33645892 (R,R)-tramadol increases expression EXP 6480464 Tramadol results in increased expression of SPP1 protein CTD PMID:33645892 (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [TNF protein results in increased expression of SPP1 mRNA] CTD PMID:22709785 (S)-nicotine increases expression ISO RGD:736066 6480464 Nicotine results in increased expression of SPP1 protein CTD PMID:11425648 (S)-nicotine multiple interactions ISO RGD:736066 6480464 Tubocurarine inhibits the reaction [Nicotine results in increased expression of SPP1 protein] CTD PMID:11425648 1,2-dimethylhydrazine increases expression ISO RGD:11340 6480464 1, 2-Dimethylhydrazine results in increased expression of SPP1 mRNA CTD PMID:22206623 1,3,5-trinitro-1,3,5-triazinane increases expression EXP 6480464 cyclonite results in increased expression of SPP1 mRNA CTD PMID:25559034 1,4-dichlorobenzene increases expression ISO RGD:11340 6480464 4-dichlorobenzene results in increased expression of SPP1 mRNA CTD PMID:26975756 1-chloro-2,4-dinitrobenzene multiple interactions EXP 6480464 Dinitrochlorobenzene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] more ... CTD PMID:20453393 1-fluoro-2,4-dinitrobenzene increases response to substance ISO RGD:11340 6480464 SPP1 protein results in increased susceptibility to Dinitrofluorobenzene CTD PMID:14555839 1-fluoro-2,4-dinitrobenzene multiple interactions ISO RGD:11340 6480464 Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 1-methylphenanthrene multiple interactions ISO RGD:736066 6480464 [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SPP1 mRNA CTD PMID:17690111 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of SPP1 mRNA CTD PMID:18289764 , PMID:23558518 1-naphthyl isothiocyanate multiple interactions ISO RGD:736066 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of SPP1 mRNA CTD PMID:27344345 1-nitropyrene decreases expression ISO RGD:736066 6480464 1-nitropyrene results in decreased expression of SPP1 mRNA CTD PMID:19428942 11-deoxycorticosterone multiple interactions EXP 6480464 [Desoxycorticosterone co-treated with Sodium Chloride more ... CTD PMID:21135038 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO RGD:11340 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased expression of SPP1 mRNA CTD PMID:12021203 17alpha-ethynylestradiol increases expression ISO RGD:11340 6480464 Ethinyl Estradiol results in increased expression of SPP1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of SPP1 mRNA CTD PMID:17557909 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SPP1 mRNA CTD PMID:12655037 , PMID:16140622 17alpha-ethynylestradiol multiple interactions ISO RGD:11340 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPP1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol affects expression ISO RGD:736066 6480464 Ethinyl Estradiol affects the expression of SPP1 mRNA CTD PMID:20170705 17beta-estradiol increases expression ISO RGD:736066 6480464 Estradiol results in increased expression of SPP1 mRNA CTD PMID:20106945 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SPP1 mRNA CTD PMID:32741896 17beta-estradiol decreases expression ISO RGD:736066 6480464 Estradiol results in decreased expression of SPP1 mRNA CTD PMID:31646340 17beta-estradiol multiple interactions ISO RGD:736066 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of SPP1 mRNA more ... CTD PMID:20226447 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of SPP1 mRNA, Estradiol affects the expression of SPP1 protein CTD PMID:19387089 17beta-estradiol increases expression ISO RGD:11340 6480464 Estradiol results in increased expression of SPP1 mRNA CTD PMID:15289156 17beta-estradiol affects expression ISO RGD:11340 6480464 Estradiol affects the expression of SPP1 mRNA CTD PMID:15598610 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SPP1 mRNA CTD PMID:32741896 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:11340 6480464 Dihydrotestosterone results in increased expression of SPP1 mRNA CTD PMID:17023530 , PMID:17898587 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions ISO RGD:736066 6480464 1H-(1 more ... CTD PMID:22543296 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one decreases expression ISO RGD:736066 6480464 1H-(1 more ... CTD PMID:22543296 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:20959002 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO RGD:736066 6480464 2 more ... CTD PMID:23146750 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:736066 6480464 2 more ... CTD PMID:23146750 , PMID:31173147 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:11340 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11340 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SPP1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SPP1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:11340 6480464 Tetrachlorodibenzodioxin results in decreased expression of SPP1 mRNA CTD PMID:33956508 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:736066 6480464 N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SPP1 mRNA] CTD PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736066 6480464 Tetrachlorodibenzodioxin results in increased expression of SPP1 mRNA CTD PMID:20106945 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SPP1 mRNA CTD PMID:11018766 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SPP1 mRNA CTD PMID:20959002 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SPP1 mRNA] CTD PMID:11018766 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:11340 6480464 Tetrachlorodibenzodioxin affects the expression of SPP1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:736066 6480464 Tetrachlorodibenzodioxin affects the expression of SPP1 mRNA CTD PMID:22298810 , PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:11340 6480464 Tetrachlorodibenzodioxin results in increased expression of SPP1 mRNA CTD PMID:17975115 , PMID:29673856 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:736066 6480464 2 more ... CTD PMID:17547211 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:11340 6480464 Trinitrobenzenesulfonic Acid results in increased expression of SPP1 mRNA CTD PMID:17982090 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:11340 6480464 Trinitrobenzenesulfonic Acid promotes the reaction [SPP1 protein results in increased susceptibility to Dinitrofluorobenzene] CTD PMID:14555839 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO RGD:736066 6480464 2 more ... CTD PMID:26705709 2,6-di-tert-butyl-4-methylphenol increases expression ISO RGD:11340 6480464 Butylated Hydroxytoluene results in increased expression of SPP1 mRNA CTD PMID:19925653 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:11340 6480464 [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of SPP1 protein more ... CTD PMID:19913045 2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid multiple interactions ISO RGD:736066 6480464 anacardic acid inhibits the reaction [Tretinoin results in increased expression of SPP1 mRNA] CTD PMID:24819975 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 Drugs more ... CTD PMID:14738908 , PMID:16452496 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression EXP 6480464 Puromycin Aminonucleoside results in increased expression of SPP1 mRNA, Puromycin Aminonucleoside results in increased expression of SPP1 protein CTD PMID:14738908 , PMID:16452496 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:736066 6480464 3 more ... CTD PMID:21703328 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:736066 6480464 3 more ... CTD PMID:23146750 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:11340 6480464 tetrabromobisphenol A results in increased expression of SPP1 mRNA CTD PMID:25172293 3-aminobenzamide increases expression ISO RGD:736066 6480464 3-aminobenzamide results in increased expression of SPP1 mRNA CTD PMID:15670817 3-chloropropane-1,2-diol multiple interactions ISO RGD:11340 6480464 [alpha-Chlorohydrin co-treated with glycidol] results in increased expression of SPP1 mRNA CTD PMID:33187795 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine inhibits the reaction [Glucose results in increased secretion of SPP1 protein] CTD PMID:20453393 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of SPP1 mRNA CTD PMID:18289764 4,4'-sulfonyldiphenol increases expression ISO RGD:11340 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of SPP1 mRNA CTD PMID:30951980 4-aminophenol decreases expression EXP 6480464 4-aminophenol results in decreased expression of SPP1 mRNA CTD PMID:23558518 5-aza-2'-deoxycytidine increases expression ISO RGD:11340 6480464 Decitabine results in increased expression of SPP1 mRNA CTD PMID:27915011 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SPP1 mRNA CTD PMID:24780913 7,12-dimethyltetraphene multiple interactions ISO RGD:11340 6480464 [9 more ... CTD PMID:27891153 , PMID:32553695 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19480007 8-Br-cAMP multiple interactions EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein] more ... CTD PMID:20453393 8-Br-cAMP decreases expression ISO RGD:736066 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of SPP1 mRNA CTD PMID:22079614 8-bromo-3',5'-cyclic GMP multiple interactions EXP 6480464 8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein] more ... CTD PMID:20453393 9-cis-retinoic acid decreases expression ISO RGD:736066 6480464 Alitretinoin results in decreased expression of SPP1 mRNA, Alitretinoin results in decreased expression of SPP1 protein CTD PMID:11139446 9-cis-retinoic acid increases expression ISO RGD:11340 6480464 Alitretinoin results in increased expression of SPP1 mRNA CTD PMID:16392701 9-cis-retinoic acid decreases expression ISO RGD:11340 6480464 Alitretinoin results in decreased expression of SPP1 mRNA CTD PMID:16392701 acetaldehyde increases expression ISO RGD:736066 6480464 Acetaldehyde results in increased expression of SPP1 mRNA, Acetaldehyde results in increased expression of SPP1 protein CTD PMID:18703563 acetylsalicylic acid affects expression EXP 6480464 Aspirin affects the expression of SPP1 mRNA CTD PMID:12800193 acrylic acid multiple interactions EXP 6480464 acrylic acid analog inhibits the reaction [Ethylene Glycol results in increased expression of SPP1 protein] CTD PMID:27018375 adefovir increases secretion EXP 6480464 adefovir results in increased secretion of SPP1 protein CTD PMID:27742868 adenine multiple interactions EXP 6480464 [Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA, linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA] CTD PMID:30466616 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of SPP1 mRNA CTD PMID:22484513 , PMID:25378103 aflatoxin B1 increases expression ISO RGD:736066 6480464 Aflatoxin B1 results in increased expression of SPP1 mRNA CTD PMID:27153756 agomelatine multiple interactions EXP 6480464 agomelatine inhibits the reaction [Methotrexate results in increased expression of SPP1 protein] CTD PMID:31975554 aldehydo-D-glucose increases expression ISO RGD:11340 6480464 Glucose results in increased expression of SPP1 mRNA CTD PMID:17178593 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SPP1 mRNA CTD PMID:32643284 aldehydo-D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of SPP1 protein CTD PMID:20453393 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SPP1, Glucose results in increased expression of SPP1 mRNA CTD PMID:12505755 , PMID:20453393 aldehydo-D-glucose multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine inhibits the reaction [Glucose results in increased secretion of SPP1 protein] more ... CTD PMID:20453393 , PMID:32643284 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of SPP1 protein CTD PMID:15389522 all-trans-retinoic acid multiple interactions ISO RGD:11340 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of SPP1 mRNA, [bisphenol F co-treated with Tretinoin] results in decreased expression of SPP1 mRNA CTD PMID:30951980 all-trans-retinoic acid increases expression ISO RGD:11340 6480464 Tretinoin results in increased expression of SPP1 mRNA CTD PMID:16392701 more ... all-trans-retinoic acid increases expression ISO RGD:736066 6480464 Tretinoin results in increased expression of SPP1 mRNA CTD PMID:15498508 more ... all-trans-retinoic acid multiple interactions ISO RGD:736066 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of SPP1 mRNA more ... CTD PMID:15894607 , PMID:24819975 all-trans-retinoic acid decreases expression ISO RGD:11340 6480464 Tretinoin results in decreased expression of SPP1 mRNA CTD PMID:16392701 , PMID:16604517 allyl alcohol increases expression EXP 6480464 allyl alcohol results in increased expression of SPP1 mRNA CTD PMID:23558518 Allylamine increases expression EXP 6480464 Allylamine results in increased expression of SPP1 mRNA, Allylamine results in increased expression of SPP1 protein CTD PMID:15910882 , PMID:23558518 Allylamine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA], Hydrogen Peroxide inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA] CTD PMID:15910882 aluminium oxide increases expression ISO RGD:736066 6480464 Aluminum Oxide results in increased expression of SPP1 mRNA CTD PMID:19464052 aluminium oxide decreases secretion ISO RGD:736066 6480464 Aluminum Oxide results in decreased secretion of SPP1 protein CTD PMID:25216247 aluminium oxide multiple interactions ISO RGD:11340 6480464 [Aluminum Oxide co-treated with Nanotubes more ... CTD PMID:25216247 aluminium oxide multiple interactions ISO RGD:736066 6480464 [Aluminum Oxide co-treated with Nanotubes more ... CTD PMID:25216247 aminoglutethimide decreases expression EXP 6480464 Aminoglutethimide results in decreased expression of SPP1 mRNA CTD PMID:23558518 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SPP1 mRNA CTD PMID:16483693 amphotericin B affects expression EXP 6480464 Amphotericin B affects the expression of SPP1 mRNA CTD PMID:20623750 amphotericin B methyl ester increases expression ISO RGD:11340 6480464 methylamphotericin B results in increased expression of SPP1 mRNA CTD PMID:22863853 andrographolide multiple interactions ISO RGD:11340 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SPP1 mRNA CTD PMID:19737545 angiotensin II increases expression ISO RGD:11340 155260287 Angiotensin II increases expression of Spp1 protein in vascular smooth muscle cells RGD aniline increases expression ISO RGD:11340 6480464 aniline results in increased expression of SPP1 mRNA CTD PMID:22016648 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [FGF1 protein results in increased expression of SPP1 mRNA] CTD PMID:15121739 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:11340 6480464 pyrazolanthrone inhibits the reaction [Ketoglutaric Acids results in increased expression of SPP1 protein] CTD PMID:31051157 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:736066 6480464 pyrazolanthrone inhibits the reaction [Ketoglutaric Acids results in increased expression of SPP1 protein] CTD PMID:31051157 anthracen-2-amine increases expression EXP 6480464 2-anthramine results in increased expression of SPP1 mRNA CTD PMID:31714650 aristolochic acid A multiple interactions EXP 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of SPP1 protein CTD PMID:23912714 aristolochic acid A decreases expression ISO RGD:736066 6480464 aristolochic acid I results in decreased expression of SPP1 mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO RGD:11340 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SPP1 mRNA CTD PMID:23650126 arsenite(3-) decreases expression ISO RGD:11340 6480464 arsenite results in decreased expression of SPP1 mRNA CTD PMID:33053406 arsenite(3-) decreases expression ISO RGD:736066 6480464 arsenite results in decreased expression of SPP1 mRNA CTD PMID:31646340 arsenite(3-) multiple interactions ISO RGD:736066 6480464 Fulvestrant inhibits the reaction [arsenite results in decreased expression of SPP1 mRNA] CTD PMID:31646340 arsenous acid multiple interactions ISO RGD:736066 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of SPP1 mRNA CTD PMID:15894607 arsenous acid decreases expression ISO RGD:736066 6480464 Arsenic Trioxide results in decreased expression of SPP1 mRNA CTD PMID:20471514 asbestos increases expression ISO RGD:736066 6480464 Asbestos results in increased expression of SPP1 protein CTD PMID:16221779 asperentin increases expression ISO RGD:11340 6480464 cladosporin results in increased expression of SPP1 mRNA CTD PMID:19818335 astaxanthin multiple interactions ISO RGD:11340 6480464 astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA] CTD PMID:16964424 aucubin increases expression ISO RGD:736066 6480464 aucubin results in increased expression of SPP1 protein CTD PMID:29408431 bacitracin increases expression EXP 6480464 Bacitracin results in increased expression of SPP1 mRNA CTD PMID:18289764 benazepril decreases expression EXP 6480464 benazepril results in decreased expression of SPP1 mRNA CTD PMID:11867951 benzo[a]pyrene decreases expression ISO RGD:11340 6480464 Benzo(a)pyrene results in decreased expression of SPP1 mRNA CTD PMID:19770486 benzo[a]pyrene affects methylation ISO RGD:736066 6480464 Benzo(a)pyrene affects the methylation of SPP1 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:736066 6480464 Benzo(a)pyrene results in increased expression of SPP1 mRNA CTD PMID:16269432 more ... benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 benzo[a]pyrene multiple interactions ISO RGD:736066 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 benzo[a]pyrene increases expression ISO RGD:11340 6480464 Benzo(a)pyrene results in increased expression of SPP1 mRNA CTD PMID:21569818 , PMID:22228805 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of SPP1 mRNA CTD PMID:18711122 benzo[b]fluoranthene decreases expression ISO RGD:11340 6480464 benzo(b)fluoranthene results in decreased expression of SPP1 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions ISO RGD:736066 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of SPP1 mRNA CTD PMID:17690111 berberine increases expression ISO RGD:736066 6480464 Berberine results in increased expression of SPP1 mRNA, Berberine results in increased expression of SPP1 protein CTD PMID:26478571 berberine multiple interactions ISO RGD:736066 6480464 CTNNB1 mutant form inhibits the reaction [Berberine results in increased expression of SPP1 protein], DKK1 protein inhibits the reaction [Berberine results in increased expression of SPP1 protein] CTD PMID:26478571 beta-naphthoflavone multiple interactions ISO RGD:11340 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SPP1 mRNA CTD PMID:19737545 beta-naphthoflavone decreases expression ISO RGD:736066 6480464 beta-Naphthoflavone results in decreased expression of SPP1 mRNA CTD PMID:32858204 bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of SPP1 mRNA CTD PMID:16648578 bezafibrate multiple interactions ISO RGD:736066 6480464 Bezafibrate inhibits the reaction [IL6 protein results in increased expression of SPP1 mRNA] more ... CTD PMID:17360982 bezafibrate decreases expression ISO RGD:736066 6480464 Bezafibrate results in decreased expression of SPP1 protein CTD PMID:17360982 bis(2-chloroethyl) sulfide increases expression ISO RGD:11340 6480464 Mustard Gas results in increased expression of SPP1 mRNA CTD PMID:15674843 , PMID:15674844 bis(2-chloroethyl) sulfide increases expression ISO RGD:736066 6480464 Mustard Gas results in increased expression of SPP1 mRNA CTD PMID:33491125 bis(2-chloroethyl) sulfide increases secretion ISO RGD:736066 6480464 Mustard Gas results in increased secretion of SPP1 protein CTD PMID:33491125 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:11340 6480464 Diethylhexyl Phthalate results in decreased expression of SPP1 mRNA CTD PMID:28085963 bis(2-ethylhexyl) phthalate increases expression ISO RGD:736066 6480464 Diethylhexyl Phthalate results in increased expression of SPP1 mRNA CTD PMID:28412506 , PMID:31163220 bisphenol A affects expression ISO RGD:736066 6480464 bisphenol A affects the expression of SPP1 mRNA CTD PMID:20170705 , PMID:30903817 bisphenol A decreases expression ISO RGD:11340 6480464 bisphenol A results in decreased expression of SPP1 mRNA CTD PMID:32156529 bisphenol A decreases methylation ISO RGD:736066 6480464 bisphenol A results in decreased methylation of SPP1 gene CTD PMID:31601247 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SPP1 mRNA CTD PMID:31697385 bisphenol A multiple interactions ISO RGD:11340 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of SPP1 mRNA CTD PMID:30951980 bisphenol A increases expression ISO RGD:11340 6480464 bisphenol A results in increased expression of SPP1 mRNA CTD PMID:30951980 bisphenol A increases expression ISO RGD:736066 6480464 bisphenol A results in increased expression of SPP1 mRNA CTD PMID:29718440 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SPP1 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SPP1 mRNA CTD PMID:22504913 more ... bisphenol F multiple interactions ISO RGD:11340 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of SPP1 mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:11340 6480464 bisphenol F results in increased expression of SPP1 mRNA CTD PMID:30951980 bleomycin A2 increases expression ISO RGD:11340 6480464 Bleomycin results in increased expression of SPP1 mRNA, Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 , PMID:29175452 bortezomib decreases expression ISO RGD:736066 6480464 Bortezomib results in decreased expression of SPP1 mRNA CTD PMID:20471514 , PMID:25913414 budesonide increases expression ISO RGD:11340 6480464 Budesonide results in increased expression of SPP1 protein CTD PMID:21885873 Butylparaben multiple interactions ISO RGD:11340 6480464 NR3C1 protein promotes the reaction [butylparaben results in decreased expression of SPP1 mRNA], PPARG protein inhibits the reaction [butylparaben results in decreased expression of SPP1 mRNA] CTD PMID:28527915 Butylparaben decreases expression ISO RGD:11340 6480464 butylparaben results in decreased expression of SPP1 mRNA CTD PMID:28527915 butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of SPP1 mRNA CTD PMID:12800193 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of SPP1 mRNA CTD PMID:20471445 cadmium atom increases expression ISO RGD:736066 6480464 Cadmium results in increased expression of SPP1 mRNA CTD PMID:17547211 cadmium atom multiple interactions ISO RGD:11340 6480464 [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA CTD PMID:31904401 cadmium atom decreases expression ISO RGD:736066 6480464 Cadmium results in decreased expression of SPP1 mRNA CTD PMID:31646340 cadmium atom multiple interactions ISO RGD:736066 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SPP1 mRNA, Cadmium inhibits the reaction [Fulvestrant results in increased expression of SPP1 mRNA] CTD PMID:29741670 , PMID:31646340 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of SPP1 mRNA, Cadmium results in increased expression of SPP1 protein CTD PMID:17327700 , PMID:25343288 cadmium dichloride increases expression ISO RGD:736066 6480464 Cadmium Chloride results in increased expression of SPP1 mRNA CTD PMID:17547211 cadmium dichloride increases export EXP 6480464 Cadmium Chloride results in increased export of SPP1 protein CTD PMID:29421648 cadmium dichloride multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cadmium Chloride results in increased export of SPP1 protein] CTD PMID:29421648 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of SPP1 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO RGD:11340 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA, [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA CTD PMID:19840844 , PMID:31904401 cadmium dichloride decreases expression ISO RGD:736066 6480464 Cadmium Chloride results in decreased expression of SPP1 mRNA CTD PMID:22019892 cadmium dichloride multiple interactions ISO RGD:736066 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in decreased expression of SPP1 mRNA], [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SPP1 mRNA CTD PMID:22019892 , PMID:29741670 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SPP1 mRNA, Cadmium Chloride results in increased expression of SPP1 protein CTD PMID:17327700 , PMID:26815315 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of SPP1 mRNA CTD PMID:30423288 caffeine affects phosphorylation ISO RGD:736066 6480464 Caffeine affects the phosphorylation of SPP1 protein CTD PMID:35688186 calciol multiple interactions ISO RGD:736066 6480464 [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein more ... CTD PMID:17692823 , PMID:22940495 calcitriol multiple interactions ISO RGD:11340 6480464 Calcitriol promotes the reaction [CREBBP protein binds to SPP1 promoter] more ... CTD PMID:10777672 , PMID:15647825 calcitriol increases expression ISO RGD:736066 6480464 Calcitriol results in increased expression of SPP1 mRNA CTD PMID:12016462 more ... calcitriol increases activity ISO RGD:11340 6480464 Calcitriol results in increased activity of SPP1 promoter CTD PMID:10777672 calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of SPP1 protein CTD PMID:19092814 calcitriol multiple interactions EXP 6480464 [glyoxylic acid co-treated with Calcitriol] results in increased expression of SPP1 mRNA CTD PMID:7571189 calcitriol increases expression ISO RGD:11340 6480464 Calcitriol results in increased expression of SPP1 mRNA CTD PMID:16889531 calcitriol multiple interactions ISO RGD:736066 6480464 [Calcitriol co-treated with resveratrol] results in increased expression of SPP1 mRNA CTD PMID:16267019 calcium atom increases expression ISO RGD:11340 6480464 Calcium results in increased expression of SPP1 mRNA CTD PMID:12788230 calcium atom affects expression EXP 6480464 Calcium affects the expression of SPP1 mRNA CTD PMID:15913539 calcium atom multiple interactions ISO RGD:11340 6480464 Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA], Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA] CTD PMID:12788230 calcium carbonate decreases expression ISO RGD:11340 6480464 Calcium Carbonate results in decreased expression of SPP1 protein CTD PMID:17977878 calcium(0) increases expression ISO RGD:11340 6480464 Calcium results in increased expression of SPP1 mRNA CTD PMID:12788230 calcium(0) affects expression EXP 6480464 Calcium affects the expression of SPP1 mRNA CTD PMID:15913539 calcium(0) multiple interactions ISO RGD:11340 6480464 Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA], Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA] CTD PMID:12788230 cannabidiol increases expression ISO RGD:736066 6480464 Cannabidiol results in increased expression of SPP1 mRNA, Cannabidiol results in increased expression of SPP1 protein CTD PMID:32656944 more ... capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of SPP1 protein CTD PMID:22150557 capsaicin multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein] more ... CTD PMID:22150557 carbamazepine affects expression ISO RGD:736066 6480464 Carbamazepine affects the expression of SPP1 mRNA CTD PMID:25979313 carbofuran increases expression EXP 6480464 Carbofuran results in increased expression of SPP1 mRNA CTD PMID:20211217 carbon nanotube affects expression ISO RGD:11340 6480464 Nanotubes, Carbon affects the expression of SPP1 mRNA CTD PMID:23845593 carbon nanotube multiple interactions ISO RGD:11340 6480464 [Aluminum Oxide co-treated with Nanotubes more ... CTD PMID:25216247 , PMID:25807359 carbon nanotube increases secretion ISO RGD:736066 6480464 Nanotubes, Carbon results in increased secretion of SPP1 protein CTD PMID:25216247 carbon nanotube multiple interactions ISO RGD:736066 6480464 [Aluminum Oxide co-treated with Nanotubes more ... CTD PMID:25216247 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:19836432 more ... carbon nanotube increases secretion ISO RGD:11340 6480464 Nanotubes, Carbon results in increased secretion of SPP1 protein CTD PMID:25216247 carbon nanotube increases expression ISO RGD:11340 6480464 Nanotubes more ... CTD PMID:25216247 more ... celecoxib multiple interactions EXP 6480464 Celecoxib inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:19356721 ceric oxide decreases expression EXP 6480464 ceric oxide results in decreased expression of SPP1 mRNA CTD PMID:29463257 CGP 52608 multiple interactions ISO RGD:736066 6480464 CGP 52608 promotes the reaction [RORA protein binds to SPP1 gene], CGP 52608 promotes the reaction [RORA protein binds to SPP1 promoter] CTD PMID:28238834 CGP 52608 increases expression ISO RGD:736066 6480464 CGP 52608 results in increased expression of SPP1 mRNA CTD PMID:28238834 chitosan increases expression ISO RGD:736066 6480464 Chitosan results in increased expression of SPP1 mRNA CTD PMID:25246786 chloroprene increases expression ISO RGD:11340 6480464 Chloroprene results in increased expression of SPP1 mRNA CTD PMID:23125180 chlorpromazine multiple interactions ISO RGD:736066 6480464 [Chlorpromazine co-treated with Cholic Acids] affects the expression of SPP1 mRNA CTD PMID:27344345 choline multiple interactions ISO RGD:11340 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPP1 mRNA more ... CTD PMID:20938992 , PMID:25712622 chrysene decreases expression ISO RGD:11340 6480464 chrysene results in decreased expression of SPP1 mRNA CTD PMID:26377693 cisplatin increases secretion EXP 6480464 Cisplatin results in increased secretion of SPP1 protein CTD PMID:28885000 cisplatin multiple interactions ISO RGD:736066 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SPP1 mRNA CTD PMID:27392435 cisplatin decreases expression ISO RGD:736066 6480464 Cisplatin results in decreased expression of SPP1 mRNA CTD PMID:11099651 cisplatin affects expression EXP 6480464 Cisplatin affects the expression of SPP1 mRNA CTD PMID:20623750 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of SPP1 mRNA, Cisplatin results in increased expression of SPP1 protein CTD PMID:11231351 more ... cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of SPP1 mRNA CTD PMID:22023808 cisplatin affects expression ISO RGD:11340 6480464 Cisplatin affects the expression of SPP1 mRNA CTD PMID:21151649 Clofop multiple interactions ISO RGD:736066 6480464 fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA], PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]] CTD PMID:17360982 clozapine decreases expression ISO RGD:736066 6480464 Clozapine results in decreased expression of SPP1 mRNA CTD PMID:17346280 cobalt atom multiple interactions ISO RGD:736066 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of SPP1 mRNA CTD PMID:18078969 cobalt dichloride multiple interactions ISO RGD:736066 6480464 cobaltous chloride affects the reaction [BMP2 protein results in increased expression of SPP1 mRNA] CTD PMID:26054564 cobalt dichloride increases expression ISO RGD:736066 6480464 cobaltous chloride results in increased expression of SPP1 mRNA CTD PMID:19376846 cobalt dichloride increases expression EXP 6480464 cobaltous chloride deficiency results in increased expression of SPP1 protein more ... CTD PMID:19356721 more ... cobalt dichloride multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] more ... CTD PMID:19356721 copper atom increases expression EXP 6480464 Copper results in increased expression of SPP1 mRNA CTD PMID:22465980 , PMID:30556269 copper atom multiple interactions ISO RGD:11340 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of SPP1 mRNA more ... CTD PMID:15467011 , PMID:16629173 copper(0) increases expression EXP 6480464 Copper results in increased expression of SPP1 mRNA CTD PMID:22465980 , PMID:30556269 copper(0) multiple interactions ISO RGD:11340 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of SPP1 mRNA more ... CTD PMID:15467011 , PMID:16629173 copper(II) sulfate increases expression ISO RGD:736066 6480464 Copper Sulfate results in increased expression of SPP1 mRNA CTD PMID:19549813 corticosterone multiple interactions EXP 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of SPP1 mRNA] CTD PMID:30423288 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of SPP1 mRNA CTD PMID:30423288 crocidolite asbestos increases expression ISO RGD:736066 6480464 Asbestos, Crocidolite results in increased expression of SPP1 protein CTD PMID:21570478 crocidolite asbestos increases expression ISO RGD:11340 6480464 Asbestos, Crocidolite results in increased expression of SPP1 mRNA CTD PMID:23917077 , PMID:29507420 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of SPP1 mRNA CTD PMID:26577399 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cadmium Chloride results in increased export of SPP1 protein] CTD PMID:29421648 cyanuric acid multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of SPP1 mRNA more ... CTD PMID:21784140 more ... cyclophosphamide affects response to substance ISO RGD:736066 6480464 SPP1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of SPP1 mRNA CTD PMID:23558518 cyclophosphamide affects expression EXP 6480464 Cyclophosphamide affects the expression of SPP1 mRNA CTD PMID:20623750 cyclosporin A decreases expression ISO RGD:736066 6480464 Cyclosporine results in decreased expression of SPP1 mRNA CTD PMID:20106945 , PMID:27989131 cyclosporin A increases expression ISO RGD:736066 6480464 Cyclosporine results in increased expression of SPP1 mRNA CTD PMID:25562108 more ... cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of SPP1 mRNA CTD PMID:21865292 , PMID:23558518 cypermethrin decreases expression ISO RGD:11340 6480464 cypermethrin results in decreased expression of SPP1 mRNA CTD PMID:29020013 D-glucose increases expression ISO RGD:11340 6480464 Glucose results in increased expression of SPP1 mRNA CTD PMID:17178593 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SPP1 mRNA CTD PMID:32643284 D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of SPP1 protein CTD PMID:20453393 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SPP1, Glucose results in increased expression of SPP1 mRNA CTD PMID:12505755 , PMID:20453393 D-glucose multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine inhibits the reaction [Glucose results in increased secretion of SPP1 protein] more ... CTD PMID:20453393 , PMID:32643284 DDT increases expression ISO RGD:736066 6480464 DDT results in increased expression of SPP1 mRNA CTD PMID:25014179 DDT decreases expression EXP 6480464 DDT results in decreased expression of SPP1 mRNA CTD PMID:30207508 decabromodiphenyl ether multiple interactions EXP 6480464 [Flame Retardants co-treated with pentabromodiphenyl ether co-treated with decabromobiphenyl ether co-treated with hexabromocyclododecane] results in decreased expression of SPP1 mRNA CTD PMID:32207525 deoxynivalenol decreases phosphorylation ISO RGD:11340 6480464 deoxynivalenol results in decreased phosphorylation of SPP1 protein CTD PMID:23352502 deoxynivalenol increases expression ISO RGD:736066 6480464 deoxynivalenol results in increased expression of SPP1 mRNA CTD PMID:27757495 dexamethasone increases expression ISO RGD:736066 6480464 Dexamethasone results in increased expression of SPP1 mRNA CTD PMID:19853017 dexamethasone multiple interactions ISO RGD:736066 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA, PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA] CTD PMID:22940495 dexamethasone multiple interactions ISO RGD:11340 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA more ... CTD PMID:24116280 , PMID:26492236 dexamethasone decreases expression ISO RGD:11340 6480464 Dexamethasone results in decreased expression of SPP1 mRNA, Dexamethasone results in decreased expression of SPP1 protein CTD PMID:22733784 , PMID:24116280 dextran sulfate increases expression ISO RGD:11340 6480464 Dextran Sulfate results in increased expression of SPP1 mRNA CTD PMID:32033881 dextran sulfate decreases expression ISO RGD:11340 6480464 Dextran Sulfate results in decreased expression of SPP1 protein CTD PMID:35999755 dextran sulfate multiple interactions ISO RGD:11340 6480464 Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of SPP1 mRNA] CTD PMID:32033881 diamminedichloroplatinum decreases expression ISO RGD:736066 6480464 transplatin results in decreased expression of SPP1 mRNA CTD PMID:11099651 diarsenic trioxide decreases expression ISO RGD:736066 6480464 Arsenic Trioxide results in decreased expression of SPP1 mRNA CTD PMID:20471514 diarsenic trioxide multiple interactions ISO RGD:736066 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of SPP1 mRNA CTD PMID:15894607 dibenz[a,h]anthracene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 dibenz[a,h]anthracene multiple interactions ISO RGD:736066 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 dibenzo[a,l]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with dibenzo(a, l)pyrene] affects the expression of SPP1 mRNA CTD PMID:18711122 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of SPP1 mRNA CTD PMID:21266533 diethylstilbestrol increases expression ISO RGD:11340 6480464 Diethylstilbestrol results in increased expression of SPP1 mRNA CTD PMID:15289156 dioxygen multiple interactions EXP 6480464 Rolipram inhibits the reaction [Oxygen results in increased expression of SPP1 mRNA], Rolipram inhibits the reaction [Oxygen results in increased expression of SPP1 protein] CTD PMID:18941502 dioxygen multiple interactions ISO RGD:11340 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of SPP1 mRNA CTD PMID:19640911 dioxygen increases expression ISO RGD:736066 6480464 Oxygen deficiency results in increased expression of SPP1 mRNA CTD PMID:24236059 dioxygen increases expression EXP 6480464 Oxygen results in increased expression of SPP1 mRNA, Oxygen results in increased expression of SPP1 protein CTD PMID:18941502 dipyridamole multiple interactions EXP 6480464 Dinitrochlorobenzene inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] more ... CTD PMID:19356721 , PMID:20453393 disodium selenite multiple interactions ISO RGD:11340 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of SPP1 mRNA CTD PMID:23274088 divanadium pentaoxide increases expression EXP 6480464 vanadium pentoxide results in increased expression of SPP1 mRNA CTD PMID:17134509 dorsomorphin multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:11340 6480464 DMD protein affects the reaction [Doxorubicin results in decreased expression of SPP1 mRNA] CTD PMID:17888722 doxorubicin decreases expression ISO RGD:736066 6480464 Doxorubicin results in decreased expression of SPP1 mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:11340 6480464 Doxorubicin results in increased expression of SPP1 mRNA CTD PMID:15033991 , PMID:22016648 doxorubicin decreases expression ISO RGD:11340 6480464 Doxorubicin results in decreased expression of SPP1 mRNA CTD PMID:17888722 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of SPP1 mRNA, Doxorubicin results in increased expression of SPP1 protein CTD PMID:11972865 more ... elemental selenium decreases expression ISO RGD:11340 6480464 Selenium results in decreased expression of SPP1 protein CTD PMID:15318939 enalapril multiple interactions ISO RGD:11340 6480464 [Enalapril co-treated with paricalcitol] results in decreased expression of SPP1 mRNA CTD PMID:25037058 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of SPP1 mRNA], Enalapril inhibits the reaction [Ethanol results in decreased expression of SPP1 mRNA] CTD PMID:30423288 , PMID:31887396 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of SPP1 mRNA CTD PMID:29391264 entinostat increases expression ISO RGD:736066 6480464 entinostat results in increased expression of SPP1 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 Erionite decreases expression ISO RGD:11340 6480464 erionite results in decreased expression of SPP1 mRNA CTD PMID:29279043 ethanol increases expression ISO RGD:11340 6480464 Ethanol results in increased expression of SPP1 mRNA, Ethanol results in increased expression of SPP1 protein CTD PMID:18703563 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of SPP1 mRNA CTD PMID:31887396 ethanol decreases expression ISO RGD:736066 6480464 Ethanol results in decreased expression of SPP1 mRNA CTD PMID:31059573 ethanol multiple interactions EXP 6480464 Enalapril inhibits the reaction [Ethanol results in decreased expression of SPP1 mRNA] more ... CTD PMID:18703563 more ... ethanol increases expression EXP 6480464 Ethanol results in increased expression of SPP1 mRNA, Ethanol results in increased expression of SPP1 protein CTD PMID:18703563 , PMID:33645892 ethanol multiple interactions ISO RGD:11340 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of SPP1 mRNA more ... CTD PMID:18703563 , PMID:30517762 ethanol increases expression ISO RGD:736066 6480464 Ethanol results in increased expression of SPP1 protein CTD PMID:18703563 ethylene glycol multiple interactions EXP 6480464 [Flavonoids co-treated with Plant Extracts] inhibits the reaction [Ethylene Glycol results in increased expression of SPP1 protein], acrylic acid analog inhibits the reaction [Ethylene Glycol results in increased expression of SPP1 protein] CTD PMID:27018375 , PMID:27241030 ethylene glycol increases expression EXP 6480464 Ethylene Glycol results in increased expression of SPP1 protein CTD PMID:24145091 more ... etoposide affects response to substance ISO RGD:736066 6480464 SPP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 etoposide decreases expression ISO RGD:11340 6480464 Etoposide results in decreased expression of SPP1 mRNA CTD PMID:25270620 Falecalcitriol increases expression ISO RGD:736066 6480464 26 more ... CTD PMID:12016462 flavonoids multiple interactions EXP 6480464 [Flavonoids co-treated with Plant Extracts] inhibits the reaction [Ethylene Glycol results in increased expression of SPP1 protein] CTD PMID:27241030 flunisolide increases expression ISO RGD:11340 6480464 flunisolide results in increased expression of SPP1 protein CTD PMID:21885873 fluoranthene multiple interactions ISO RGD:736066 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of SPP1 mRNA CTD PMID:17690111 fluoranthene multiple interactions ISO RGD:11340 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of SPP1 mRNA CTD PMID:28329830 fluvastatin multiple interactions EXP 6480464 fluvastatin inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SPP1 mRNA] CTD PMID:16452496 folic acid multiple interactions ISO RGD:11340 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPP1 mRNA CTD PMID:20938992 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased secretion of SPP1 protein] CTD PMID:23596885 fulvestrant increases expression ISO RGD:736066 6480464 Fulvestrant results in increased expression of SPP1 mRNA CTD PMID:31646340 fulvestrant multiple interactions ISO RGD:736066 6480464 Cadmium inhibits the reaction [Fulvestrant results in increased expression of SPP1 mRNA] more ... CTD PMID:31646340 furan increases expression EXP 6480464 furan results in increased expression of SPP1 mRNA CTD PMID:26194646 , PMID:27387713 gadodiamide hydrate increases expression EXP 6480464 gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 gadolinium atom multiple interactions ISO RGD:736066 6480464 [gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SPP1 mRNA CTD PMID:34878122 gadolinium trichloride multiple interactions ISO RGD:736066 6480464 [gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SPP1 mRNA CTD PMID:34878122 gallocatechin increases expression EXP 6480464 gallocatechol results in increased expression of SPP1 mRNA CTD PMID:21877759 gemcitabine increases expression ISO RGD:736066 6480464 Gemcitabine results in increased expression of SPP1 mRNA CTD PMID:17039268 genistein increases expression EXP 6480464 Genistein results in increased expression of SPP1 mRNA CTD PMID:21877759 genistein decreases expression EXP 6480464 Genistein results in decreased expression of SPP1 mRNA CTD PMID:22504913 genistein increases expression ISO RGD:11340 6480464 Genistein results in increased expression of SPP1 mRNA CTD PMID:15289156 gentamycin affects expression EXP 6480464 Gentamicins affects the expression of SPP1 mRNA CTD PMID:20623750 gentamycin multiple interactions EXP 6480464 Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 mRNA], Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 protein] CTD PMID:26779593 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SPP1 mRNA, Gentamicins results in increased expression of SPP1 protein CTD PMID:11231351 more ... Ginkgoic acid multiple interactions ISO RGD:736066 6480464 ginkgolic acid inhibits the reaction [Tretinoin results in increased expression of SPP1 mRNA] CTD PMID:24819975 glucose increases expression ISO RGD:11340 6480464 Glucose results in increased expression of SPP1 mRNA CTD PMID:17178593 glucose decreases expression EXP 6480464 Glucose results in decreased expression of SPP1 mRNA CTD PMID:32643284 glucose increases secretion EXP 6480464 Glucose results in increased secretion of SPP1 protein CTD PMID:20453393 glucose increases expression EXP 6480464 Glucose results in increased expression of SPP1, Glucose results in increased expression of SPP1 mRNA CTD PMID:12505755 , PMID:20453393 glucose multiple interactions EXP 6480464 1-Methyl-3-isobutylxanthine inhibits the reaction [Glucose results in increased secretion of SPP1 protein] more ... CTD PMID:20453393 , PMID:32643284 glycerol 2-phosphate multiple interactions ISO RGD:736066 6480464 [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein more ... CTD PMID:17692823 , PMID:22940495 glycerol 2-phosphate multiple interactions ISO RGD:11340 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA more ... CTD PMID:26492236 glycidol multiple interactions ISO RGD:11340 6480464 [alpha-Chlorohydrin co-treated with glycidol] results in increased expression of SPP1 mRNA CTD PMID:33187795 glyoxylic acid multiple interactions EXP 6480464 [glyoxylic acid co-treated with Calcitriol] results in increased expression of SPP1 mRNA CTD PMID:7571189 glyoxylic acid increases expression EXP 6480464 glyoxylic acid results in increased expression of SPP1 protein CTD PMID:8325891 graphite decreases expression ISO RGD:11340 6480464 Graphite results in decreased expression of SPP1 mRNA CTD PMID:27440207 graphite increases expression EXP 6480464 Graphite results in increased expression of SPP1 mRNA CTD PMID:29933104 griseofulvin affects expression ISO RGD:11340 6480464 Griseofulvin affects the expression of SPP1 mRNA CTD PMID:12735108 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of SPP1 protein CTD PMID:21259293 , PMID:23136149 hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA] CTD PMID:15910882 hydrogen peroxide increases expression ISO RGD:736066 6480464 Hydrogen Peroxide results in increased expression of SPP1 mRNA CTD PMID:33491125 hydrogen peroxide increases secretion ISO RGD:736066 6480464 Hydrogen Peroxide results in increased secretion of SPP1 protein CTD PMID:33491125 icariin multiple interactions ISO RGD:11340 6480464 NOG protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA], SMAD6 protein inhibits the reaction [icariin results in increased expression of SPP1 mRNA] CTD PMID:18295595 icariin increases expression EXP 6480464 icariin results in increased expression of SPP1 mRNA CTD PMID:16696327 , PMID:18236786 icariin increases expression ISO RGD:11340 6480464 icariin results in increased expression of SPP1 mRNA CTD PMID:18295595 imperatorin multiple interactions EXP 6480464 imperatorin analog inhibits the reaction [AGT protein results in increased expression of SPP1 protein] CTD PMID:25727310 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of SPP1 mRNA CTD PMID:21396975 inulin multiple interactions ISO RGD:11340 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPP1 mRNA CTD PMID:36331819 iron(2+) sulfate (anhydrous) decreases expression ISO RGD:736066 6480464 ferrous sulfate results in decreased expression of SPP1 mRNA CTD PMID:19428942 isocyanuric acid multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of SPP1 mRNA more ... CTD PMID:21784140 more ... isoniazide affects expression EXP 6480464 Isoniazid affects the expression of SPP1 mRNA CTD PMID:20623750 isoniazide decreases expression ISO RGD:736066 6480464 Isoniazid results in decreased expression of SPP1 mRNA CTD PMID:30008028 isonicotinamide increases expression ISO RGD:736066 6480464 isonicotinamide results in increased expression of SPP1 mRNA CTD PMID:21745208 isoprenaline increases expression ISO RGD:11340 6480464 Isoproterenol results in increased expression of SPP1 mRNA CTD PMID:20003209 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of SPP1 mRNA CTD PMID:20211217 more ... isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of SPP1 mRNA CTD PMID:24286936 isoprenaline decreases expression ISO RGD:11340 6480464 Isoproterenol results in decreased expression of SPP1 mRNA CTD PMID:21335049 isotretinoin increases expression ISO RGD:736066 6480464 Isotretinoin results in increased expression of SPP1 mRNA CTD PMID:18769122 ivermectin decreases expression ISO RGD:736066 6480464 Ivermectin results in decreased expression of SPP1 protein CTD PMID:32959892 jaspamide decreases expression ISO RGD:736066 6480464 jasplakinolide results in decreased expression of SPP1 protein CTD PMID:19026636 kaempferol multiple interactions ISO RGD:11340 6480464 kaempferol inhibits the reaction [APOE affects the expression of SPP1 mRNA], kaempferol inhibits the reaction [APOE affects the expression of SPP1 protein] CTD PMID:22005275 kojic acid increases expression ISO RGD:736066 6480464 kojic acid results in increased expression of SPP1 mRNA CTD PMID:16595896 KT 5823 multiple interactions EXP 6480464 KT 5823 inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] more ... CTD PMID:20453393 L-ascorbic acid multiple interactions ISO RGD:736066 6480464 [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of SPP1 protein CTD PMID:17692823 L-ascorbic acid multiple interactions ISO RGD:11340 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SPP1 mRNA more ... CTD PMID:26492236 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:736066 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA, PARG mRNA inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of SPP1 mRNA] CTD PMID:22940495 L-methionine multiple interactions ISO RGD:11340 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPP1 mRNA more ... CTD PMID:20938992 , PMID:25712622 lead diacetate multiple interactions ISO RGD:736066 6480464 lead acetate results in increased expression of and results in increased secretion of SPP1 protein, NFE2L2 protein affects the reaction [lead acetate results in increased expression of SPP1 mRNA] CTD PMID:27562236 lead diacetate increases expression ISO RGD:11340 6480464 lead acetate results in increased expression of SPP1 mRNA CTD PMID:30312686 lead diacetate increases expression ISO RGD:736066 6480464 lead acetate results in increased expression of SPP1 mRNA CTD PMID:27562236 lead(0) affects expression ISO RGD:736066 6480464 Lead affects the expression of SPP1 mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:736066 6480464 Lead affects the expression of SPP1 mRNA CTD PMID:28903495 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of SPP1 mRNA CTD PMID:35283115 linalool multiple interactions EXP 6480464 linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA] CTD PMID:30466616 lipopolysaccharide multiple interactions ISO RGD:736066 6480464 [Aluminum Oxide co-treated with Nanotubes more ... CTD PMID:25216247 , PMID:35877022 lipopolysaccharide increases expression ISO RGD:11340 6480464 Lipopolysaccharides results in increased expression of SPP1 mRNA CTD PMID:27339419 lipopolysaccharide increases secretion ISO RGD:736066 6480464 Lipopolysaccharides results in increased secretion of SPP1 protein CTD PMID:25216247 LY 364947 decreases phosphorylation ISO RGD:736066 155260309 LY364947 decreases phosphorylation of SPP1 protein in aortic smooth muscle cells RGD LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:19356721 magnesium atom increases expression ISO RGD:736066 6480464 Magnesium results in increased expression of SPP1 protein CTD PMID:10397942 medroxyprogesterone acetate increases expression ISO RGD:736066 6480464 Medroxyprogesterone Acetate results in increased expression of SPP1 mRNA CTD PMID:20843944 melamine multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of SPP1 mRNA more ... CTD PMID:21784140 more ... mercury atom increases expression ISO RGD:736066 6480464 Mercury results in increased expression of SPP1 mRNA CTD PMID:17547211 mercury dibromide increases expression ISO RGD:736066 6480464 mercuric bromide results in increased expression of SPP1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 mercury dichloride multiple interactions ISO RGD:11340 6480464 [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of SPP1 protein CTD PMID:21084432 mercury dichloride multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 mercury dichloride increases expression ISO RGD:736066 6480464 Mercuric Chloride results in increased expression of SPP1 mRNA CTD PMID:26272509 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of SPP1 mRNA, Mercuric Chloride results in increased expression of SPP1 protein CTD PMID:11274264 mercury(0) increases expression ISO RGD:736066 6480464 Mercury results in increased expression of SPP1 mRNA CTD PMID:17547211 mesalamine multiple interactions EXP 6480464 Mesalamine inhibits the reaction [Thioacetamide results in increased expression of SPP1 protein] CTD PMID:29738702 metaproterenol increases expression EXP 6480464 Metaproterenol results in increased expression of SPP1 mRNA CTD PMID:23558518 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of SPP1 mRNA CTD PMID:23558518 methotrexate multiple interactions EXP 6480464 agomelatine inhibits the reaction [Methotrexate results in increased expression of SPP1 protein] CTD PMID:31975554 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of SPP1 protein CTD PMID:31975554 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of SPP1 protein CTD PMID:28526320 methylmercury chloride multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 methylmercury chloride increases expression ISO RGD:736066 6480464 methylmercuric chloride results in increased expression of SPP1 mRNA CTD PMID:23179753 more ... methylparaben decreases expression ISO RGD:11340 6480464 methylparaben results in decreased expression of SPP1 mRNA CTD PMID:28527915 milrinone increases expression EXP 6480464 Milrinone results in increased expression of SPP1 mRNA CTD PMID:22936366 mitoxantrone increases expression EXP 6480464 Mitoxantrone results in increased expression of SPP1 mRNA CTD PMID:23558518 mometasone furoate increases expression ISO RGD:11340 6480464 Mometasone Furoate results in increased expression of SPP1 protein CTD PMID:21885873 Morroniside affects expression ISO RGD:11340 6480464 morroniside affects the expression of SPP1 protein CTD PMID:35848187 Morroniside multiple interactions EXP 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of SPP1 mRNA] CTD PMID:32643284 Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of SPP1 mRNA CTD PMID:21515302 mycophenolic acid increases expression ISO RGD:11340 6480464 Mycophenolic Acid results in increased expression of SPP1 mRNA CTD PMID:19818335 mycotoxin increases expression ISO RGD:11340 6480464 Mycotoxins results in increased expression of SPP1 mRNA CTD PMID:19818335 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:11340 6480464 [zinc chloride co-treated with N more ... CTD PMID:19913120 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] more ... CTD PMID:20453393 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA], Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:15910882 , PMID:19356721 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of SPP1 mRNA CTD PMID:15954086 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:11340 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA more ... CTD PMID:19840844 N-methyl-N-nitrosourea decreases expression EXP 6480464 Methylnitrosourea results in decreased expression of SPP1 mRNA CTD PMID:16525678 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of SPP1 mRNA CTD PMID:19638242 N-nitrosodimethylamine increases expression ISO RGD:736066 6480464 Dimethylnitrosamine results in increased expression of SPP1 mRNA CTD PMID:17547211 naproxen multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein], Naproxen inhibits the reaction [Capsaicin results in increased expression of SPP1 protein] CTD PMID:22150557 naringin increases expression ISO RGD:11340 6480464 naringin results in increased expression of SPP1 mRNA, naringin results in increased expression of SPP1 protein CTD PMID:18495116 naringin increases secretion EXP 6480464 naringin results in increased secretion of SPP1 protein CTD PMID:23596885 naringin increases expression ISO RGD:736066 6480464 naringin results in increased expression of SPP1 mRNA, naringin results in increased expression of SPP1 protein CTD PMID:18495116 , PMID:24915843 naringin multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased secretion of SPP1 protein] CTD PMID:23596885 natamycin increases expression ISO RGD:11340 6480464 Natamycin results in increased expression of SPP1 mRNA CTD PMID:22863853 neoechinulin A increases expression ISO RGD:11340 6480464 neoechinulin A results in increased expression of SPP1 mRNA CTD PMID:19818335 nickel atom increases expression ISO RGD:11340 6480464 Nickel results in increased expression of SPP1 mRNA CTD PMID:12540486 nickel atom increases expression ISO RGD:736066 6480464 Nickel results in increased expression of SPP1 mRNA CTD PMID:24768652 , PMID:25583101 nickel dichloride increases expression ISO RGD:736066 6480464 nickel chloride results in increased expression of SPP1 mRNA CTD PMID:17547211 nickel sulfate increases expression ISO RGD:11340 6480464 nickel sulfate results in increased expression of SPP1 mRNA CTD PMID:16100012 nicotine increases expression ISO RGD:736066 6480464 Nicotine results in increased expression of SPP1 protein CTD PMID:11425648 nicotine multiple interactions ISO RGD:736066 6480464 Tubocurarine inhibits the reaction [Nicotine results in increased expression of SPP1 protein] CTD PMID:11425648 nifedipine multiple interactions ISO RGD:11340 6480464 Nifedipine inhibits the reaction [Calcium results in increased expression of SPP1 mRNA], Nifedipine inhibits the reaction [Phosphates results in increased expression of SPP1 mRNA] CTD PMID:12788230 nitric oxide decreases expression ISO RGD:11340 6480464 Nitric Oxide deficiency results in decreased expression of SPP1 mRNA CTD PMID:15878706 nitroprusside multiple interactions ISO RGD:736066 6480464 1H-(1 more ... CTD PMID:22543296 nitroprusside increases expression ISO RGD:736066 6480464 Nitroprusside results in increased expression of SPP1 mRNA CTD PMID:22543296 nystatin increases expression ISO RGD:11340 6480464 Nystatin results in increased expression of SPP1 mRNA CTD PMID:22863853 O-methyleugenol increases expression ISO RGD:736066 6480464 methyleugenol results in increased expression of SPP1 mRNA CTD PMID:32234424 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of SPP1 mRNA, ochratoxin A results in increased expression of SPP1 protein CTD PMID:18308701 , PMID:30449730 ochratoxin A increases expression ISO RGD:736066 6480464 ochratoxin A results in increased expression of SPP1 mRNA CTD PMID:30008028 okadaic acid multiple interactions ISO RGD:11340 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA CTD PMID:19840844 orciprenaline increases expression EXP 6480464 Metaproterenol results in increased expression of SPP1 mRNA CTD PMID:23558518 oxalic acid multiple interactions ISO RGD:736066 6480464 resveratrol inhibits the reaction [Oxalic Acid results in increased expression of SPP1 mRNA] CTD PMID:24145091 oxalic acid increases expression ISO RGD:736066 6480464 Oxalic Acid results in increased expression of SPP1 mRNA CTD PMID:24145091 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SPP1 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of SPP1 mRNA CTD PMID:25729387 oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of SPP1 protein CTD PMID:24486959 ozone multiple interactions ISO RGD:11340 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SPP1 mRNA more ... CTD PMID:19555225 , PMID:34911549 ozone increases expression ISO RGD:736066 6480464 Ozone results in increased expression of SPP1 mRNA CTD PMID:31476115 ozone increases expression ISO RGD:11340 6480464 Ozone results in increased expression of SPP1 mRNA CTD PMID:12763052 , PMID:25658374 ozone increases expression EXP 6480464 Ozone results in increased expression of SPP1, Ozone results in increased expression of SPP1 mRNA CTD PMID:16716893 , PMID:24103449 p-chloromercuribenzoic acid increases expression ISO RGD:736066 6480464 p-Chloromercuribenzoic Acid results in increased expression of SPP1 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 panobinostat multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:736066 6480464 panobinostat results in increased expression of SPP1 mRNA CTD PMID:26272509 paracetamol decreases response to substance ISO RGD:11340 6480464 SPP1 gene mutant form results in decreased susceptibility to Acetaminophen CTD PMID:16485898 paracetamol decreases expression ISO RGD:736066 6480464 Acetaminophen results in decreased expression of SPP1 mRNA CTD PMID:29067470 paracetamol affects expression ISO RGD:11340 6480464 Acetaminophen affects the expression of SPP1 mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:11340 6480464 Acetaminophen results in increased expression of SPP1 protein CTD PMID:17439248 paraquat increases expression ISO RGD:11340 6480464 Paraquat results in increased expression of SPP1 mRNA, Paraquat results in increased expression of SPP1 protein CTD PMID:26345256 paraquat increases expression ISO RGD:736066 6480464 Paraquat results in increased expression of SPP1 mRNA CTD PMID:35182771 paraquat increases expression EXP 6480464 Paraquat results in increased expression of SPP1 mRNA CTD PMID:32680482 paricalcitol increases expression ISO RGD:11340 6480464 paricalcitol results in increased expression of SPP1 mRNA CTD PMID:25037058 paricalcitol multiple interactions ISO RGD:736066 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of SPP1 mRNA CTD PMID:17715259 paricalcitol multiple interactions ISO RGD:11340 6480464 [Enalapril co-treated with paricalcitol] results in decreased expression of SPP1 mRNA CTD PMID:25037058 PD 0325901 multiple interactions ISO RGD:736066 6480464 [mirdametinib co-treated with (+)-JQ1 compound] results in decreased expression of SPP1 mRNA CTD PMID:25119042 PD123319 multiple interactions EXP 6480464 PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 mRNA], PD 123319 inhibits the reaction [AGT protein results in increased expression of SPP1 protein] CTD PMID:11115077 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of SPP1 mRNA CTD PMID:25710175 Pentoxifylline decreases expression EXP 6480464 Pentoxifylline results in decreased expression of SPP1 mRNA CTD PMID:14993492 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of SPP1 mRNA CTD PMID:22237054 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:11340 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPP1 mRNA CTD PMID:36331819 perfluorooctane-1-sulfonic acid affects expression ISO RGD:736066 6480464 perfluorooctane sulfonic acid affects the expression of SPP1 mRNA CTD PMID:30738844 phenobarbital affects expression ISO RGD:736066 6480464 Phenobarbital affects the expression of SPP1 mRNA CTD PMID:19084549 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of SPP1 protein CTD PMID:10406839 phenylmercury acetate increases expression ISO RGD:736066 6480464 Phenylmercuric Acetate results in increased expression of SPP1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:736066 6480464 [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]] more ... CTD PMID:11426586 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:11340 6480464 [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA, [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA CTD PMID:19840844 , PMID:31904401 phorbol 13-acetate 12-myristate increases expression ISO RGD:736066 6480464 Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA, Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein CTD PMID:11426586 , PMID:17360982 phosphonoformic acid multiple interactions ISO RGD:11340 6480464 Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA] more ... CTD PMID:12788230 more ... phosphorus atom multiple interactions ISO RGD:736066 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of SPP1 mRNA CTD PMID:17715259 phosphorus(.) multiple interactions ISO RGD:736066 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of SPP1 mRNA CTD PMID:17715259 phylloquinone multiple interactions ISO RGD:11340 6480464 [Warfarin co-treated with Vitamin K 1] results in increased expression of SPP1 mRNA CTD PMID:23990204 pioglitazone multiple interactions EXP 6480464 pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA], pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein] CTD PMID:16979161 pirinixic acid multiple interactions ISO RGD:736066 6480464 [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]] more ... CTD PMID:17360982 piroxicam decreases expression ISO RGD:736066 6480464 Piroxicam results in decreased expression of SPP1 mRNA CTD PMID:21858171 potassium bromate increases expression EXP 6480464 potassium bromate results in increased expression of SPP1 mRNA, potassium bromate results in increased expression of SPP1 protein CTD PMID:23588252 , PMID:23811332 potassium bromate increases expression ISO RGD:736066 6480464 potassium bromate results in increased expression of SPP1 mRNA CTD PMID:30008028 progesterone multiple interactions ISO RGD:736066 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of SPP1 mRNA, [Progesterone co-treated with Estradiol] results in increased expression of SPP1 mRNA CTD PMID:20226447 , PMID:20660070 protein kinase inhibitor multiple interactions ISO RGD:736066 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of SPP1 mRNA] CTD PMID:28003376 Ptaquiloside multiple interactions ISO RGD:11340 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of SPP1 mRNA CTD PMID:23274088 pyrrolidine dithiocarbamate decreases expression EXP 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of SPP1 CTD PMID:21076490 quartz increases expression EXP 6480464 Quartz results in increased expression of SPP1 mRNA CTD PMID:19836432 , PMID:32976597 quartz multiple interactions EXP 6480464 Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SPP1 mRNA] CTD PMID:32976597 quercetin decreases expression ISO RGD:736066 6480464 Quercetin results in decreased expression of SPP1 mRNA CTD PMID:20596804 quercetin multiple interactions ISO RGD:11340 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SPP1 mRNA] CTD PMID:25712622 quercetin increases expression ISO RGD:736066 6480464 Quercetin results in increased expression of SPP1 mRNA CTD PMID:16996034 , PMID:21632981 quercetin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of SPP1 mRNA] more ... CTD PMID:23223575 , PMID:26053266 quercetin increases expression EXP 6480464 Quercetin results in increased expression of SPP1 mRNA CTD PMID:26053266 raloxifene affects expression ISO RGD:736066 6480464 Raloxifene Hydrochloride affects the expression of SPP1 mRNA CTD PMID:14699072 resveratrol multiple interactions ISO RGD:736066 6480464 [Calcitriol co-treated with resveratrol] results in increased expression of SPP1 mRNA, resveratrol inhibits the reaction [Oxalic Acid results in increased expression of SPP1 mRNA] CTD PMID:16267019 , PMID:24145091 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SPP1 protein CTD PMID:24145091 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SPP1 mRNA] CTD PMID:11018766 resveratrol increases expression ISO RGD:11340 6480464 resveratrol results in increased expression of SPP1 CTD PMID:19656070 resveratrol increases expression ISO RGD:736066 6480464 resveratrol results in increased expression of SPP1 mRNA CTD PMID:16267019 , PMID:21745208 rolipram multiple interactions EXP 6480464 Rolipram inhibits the reaction [Oxygen results in increased expression of SPP1 mRNA], Rolipram inhibits the reaction [Oxygen results in increased expression of SPP1 protein] CTD PMID:18941502 rotenone increases expression ISO RGD:11340 6480464 Rotenone results in increased expression of SPP1 mRNA CTD PMID:22016648 rotenone increases expression EXP 6480464 Rotenone results in increased expression of SPP1 mRNA CTD PMID:27900601 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression ISO RGD:11340 6480464 Buthionine Sulfoximine results in decreased expression of SPP1 mRNA CTD PMID:15707499 , PMID:15878706 Salidroside increases expression ISO RGD:11340 6480464 rhodioloside results in increased expression of SPP1 mRNA CTD PMID:24055767 Salinomycin decreases expression ISO RGD:736066 6480464 salinomycin results in decreased expression of SPP1 mRNA CTD PMID:19682730 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:19356721 SB 431542 multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sclareol increases expression ISO RGD:11340 6480464 sclareol results in increased expression of SPP1 mRNA, sclareol results in increased expression of SPP1 protein CTD PMID:33423118 Se-methyl-L-selenocysteine decreases expression ISO RGD:11340 6480464 selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 Se-methylselenocysteine decreases expression ISO RGD:11340 6480464 selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 selenium atom decreases expression ISO RGD:11340 6480464 Selenium results in decreased expression of SPP1 protein CTD PMID:15318939 serpentine asbestos increases expression ISO RGD:11340 6480464 Asbestos, Serpentine results in increased expression of SPP1 mRNA CTD PMID:16251409 more ... serpentine asbestos decreases response to substance ISO RGD:11340 6480464 SPP1 gene mutant form results in decreased susceptibility to Asbestos, Serpentine CTD PMID:21514415 serpentine asbestos multiple interactions ISO RGD:11340 6480464 SPP1 gene mutant form inhibits the reaction [Asbestos more ... CTD PMID:21514415 silicon dioxide decreases expression ISO RGD:736066 6480464 Silicon Dioxide results in decreased expression of SPP1 mRNA CTD PMID:19428942 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of SPP1 mRNA CTD PMID:22431001 silicon dioxide increases expression ISO RGD:11340 6480464 Silicon Dioxide results in increased expression of SPP1 mRNA, Silicon Dioxide results in increased expression of SPP1 protein CTD PMID:26345256 more ... silicon dioxide multiple interactions ISO RGD:11340 6480464 Estrogens inhibits the reaction [Silicon Dioxide results in increased expression of SPP1 protein] CTD PMID:26955063 silver atom increases expression ISO RGD:736066 6480464 Silver results in increased expression of SPP1 mRNA CTD PMID:28959546 silver atom increases secretion ISO RGD:11340 6480464 Silver results in increased secretion of SPP1 protein CTD PMID:25458489 silver(0) increases expression ISO RGD:736066 6480464 Silver results in increased expression of SPP1 mRNA CTD PMID:28959546 silver(0) increases secretion ISO RGD:11340 6480464 Silver results in increased secretion of SPP1 protein CTD PMID:25458489 simvastatin decreases expression ISO RGD:736066 6480464 Simvastatin results in decreased expression of SPP1 mRNA CTD PMID:21109955 simvastatin increases expression ISO RGD:11340 6480464 Simvastatin results in increased expression of SPP1 protein CTD PMID:12914771 more ... simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of SPP1 CTD PMID:21076490 sirolimus multiple interactions ISO RGD:11340 6480464 Sirolimus inhibits the reaction [Ketoglutaric Acids results in increased expression of SPP1 protein] CTD PMID:31051157 sirolimus multiple interactions ISO RGD:736066 6480464 Sirolimus inhibits the reaction [Ketoglutaric Acids results in increased expression of SPP1 protein] CTD PMID:31051157 sodium arsenite increases expression ISO RGD:736066 6480464 sodium arsenite results in increased expression of SPP1 mRNA, sodium arsenite results in increased expression of SPP1 protein CTD PMID:25493608 more ... sodium arsenite decreases expression ISO RGD:11340 6480464 sodium arsenite results in decreased expression of SPP1 mRNA CTD PMID:28206643 , PMID:32068019 sodium arsenite increases expression ISO RGD:11340 6480464 sodium arsenite results in increased expression of SPP1 mRNA CTD PMID:20179202 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of SPP1 mRNA CTD PMID:25993096 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of SPP1 protein CTD PMID:23933529 sodium fluoride multiple interactions ISO RGD:11340 6480464 BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of SPP1 mRNA] more ... CTD PMID:35218729 sodium fluoride increases expression ISO RGD:11340 6480464 Sodium Fluoride results in increased expression of SPP1 mRNA, Sodium Fluoride results in increased expression of SPP1 protein CTD PMID:35218729 sodium fluoride multiple interactions EXP 6480464 Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 mRNA], Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 protein] CTD PMID:26779593 sodium fluoride decreases expression ISO RGD:11340 6480464 Sodium Fluoride results in decreased expression of SPP1 mRNA CTD PMID:27862939 sterigmatocystin increases expression ISO RGD:11340 6480464 Sterigmatocystin results in increased expression of SPP1 mRNA CTD PMID:19818335 streptozocin multiple interactions EXP 6480464 Pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA] more ... CTD PMID:16684804 , PMID:16979161 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of SPP1 mRNA, Streptozocin results in increased expression of SPP1 protein CTD PMID:16684804 more ... strontium atom increases expression ISO RGD:736066 6480464 Strontium results in increased expression of SPP1 protein CTD PMID:16886220 succimer multiple interactions ISO RGD:736066 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SPP1 mRNA CTD PMID:26378955 sulfasalazine increases expression ISO RGD:11340 6480464 Sulfasalazine results in increased expression of SPP1 mRNA CTD PMID:22016648 sulforaphane increases expression ISO RGD:736066 6480464 sulforaphane results in increased expression of SPP1 mRNA CTD PMID:26833863 , PMID:27562236 sumatriptan multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein], Sumatriptan promotes the reaction [Capsaicin results in increased expression of SPP1 protein] CTD PMID:22150557 SWINHOLIDE A increases expression ISO RGD:736066 6480464 swinholide A results in increased expression of SPP1 protein CTD PMID:19026636 SWINHOLIDE A multiple interactions ISO RGD:736066 6480464 swinholide A affects the reaction [EEF1A1 protein binds to SPP1 5' UTR] CTD PMID:19026636 tacrolimus hydrate increases expression EXP 6480464 Tacrolimus results in increased expression of SPP1 mRNA CTD PMID:12472797 , PMID:21865292 tamibarotene increases expression ISO RGD:736066 6480464 tamibarotene results in increased expression of SPP1 mRNA CTD PMID:15498508 tamoxifen affects expression ISO RGD:736066 6480464 Tamoxifen affects the expression of SPP1 mRNA CTD PMID:14699072 tamoxifen increases expression ISO RGD:736066 6480464 Tamoxifen results in increased expression of SPP1 mRNA CTD PMID:19155303 Tanshinone I multiple interactions EXP 6480464 tanshinone inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:19356721 temozolomide decreases expression ISO RGD:736066 6480464 Temozolomide results in decreased expression of SPP1 mRNA CTD PMID:31758290 Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of SPP1 mRNA CTD PMID:21515302 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SPP1 mRNA CTD PMID:32741896 tetrachloromethane affects expression ISO RGD:11340 6480464 Carbon Tetrachloride affects the expression of SPP1 mRNA CTD PMID:17484886 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SPP1 mRNA CTD PMID:23558518 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SPP1 protein CTD PMID:15548383 tetrachloromethane affects response to substance ISO RGD:11340 6480464 SPP1 protein affects the susceptibility to Carbon Tetrachloride CTD PMID:16221502 tetrachloromethane increases expression ISO RGD:11340 6480464 Carbon Tetrachloride results in increased expression of SPP1 mRNA, Carbon Tetrachloride results in increased expression of SPP1 protein CTD PMID:15070743 more ... tetrachloromethane multiple interactions ISO RGD:11340 6480464 2-cyano-3 more ... CTD PMID:15070743 more ... tetracycline increases expression ISO RGD:11340 6480464 Tetracycline results in increased expression of SPP1 mRNA CTD PMID:16917069 thioacetamide multiple interactions EXP 6480464 halofuginone inhibits the reaction [Thioacetamide results in increased expression of SPP1 mRNA], Mesalamine inhibits the reaction [Thioacetamide results in increased expression of SPP1 protein] CTD PMID:17180598 , PMID:29738702 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SPP1 mRNA, Thioacetamide results in increased expression of SPP1 protein CTD PMID:12531686 more ... thiourea multiple interactions ISO RGD:11340 6480464 Thiourea analog inhibits the reaction [IFNG protein promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SPP1 mRNA]] CTD PMID:10868913 titanium atom increases expression EXP 6480464 Titanium results in increased expression of SPP1 mRNA CTD PMID:15914587 titanium dioxide increases expression ISO RGD:11340 6480464 titanium dioxide results in increased expression of SPP1 mRNA CTD PMID:19464567 more ... titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of SPP1 mRNA CTD PMID:30012374 titanium dioxide decreases expression ISO RGD:11340 6480464 titanium dioxide results in decreased expression of SPP1 mRNA CTD PMID:29264374 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SPP1 mRNA CTD PMID:25729387 topotecan affects response to substance ISO RGD:736066 6480464 SPP1 protein affects the susceptibility to Topotecan CTD PMID:16217747 topotecan increases expression EXP 6480464 Topotecan results in increased expression of SPP1 mRNA CTD PMID:25729387 tramadol multiple interactions EXP 6480464 Ethanol promotes the reaction [Tramadol results in increased expression of SPP1 protein], Tramadol promotes the reaction [Ethanol results in increased expression of SPP1 protein] CTD PMID:33645892 tramadol increases expression EXP 6480464 Tramadol results in increased expression of SPP1 protein CTD PMID:33645892 transplatin decreases expression ISO RGD:736066 6480464 transplatin results in decreased expression of SPP1 mRNA CTD PMID:11099651 tremolite asbestos increases expression ISO RGD:11340 6480464 tremolite results in increased expression of SPP1 mRNA CTD PMID:29279043 trichloroethene multiple interactions ISO RGD:11340 6480464 [Trichloroethylene co-treated with Mercuric Chloride] results in increased expression of SPP1 protein CTD PMID:21084432 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SPP1 mRNA CTD PMID:33387578 trichloroethene decreases expression ISO RGD:11340 6480464 Trichloroethylene results in decreased expression of SPP1 mRNA CTD PMID:25026505 trichloroethene increases expression ISO RGD:11340 6480464 Trichloroethylene results in increased expression of SPP1 protein CTD PMID:21084432 trichostatin A increases expression ISO RGD:736066 6480464 trichostatin A results in increased expression of SPP1 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 trimethyltin increases expression ISO RGD:11340 6480464 trimethyltin results in increased expression of SPP1 mRNA CTD PMID:24002884 troglitazone multiple interactions ISO RGD:736066 6480464 PPARG protein affects the reaction [troglitazone results in decreased expression of SPP1 mRNA], troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA] CTD PMID:11426586 troglitazone increases expression ISO RGD:736066 6480464 troglitazone results in increased expression of SPP1 mRNA CTD PMID:25572481 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SPP1 mRNA CTD PMID:21515302 troglitazone decreases expression ISO RGD:11340 6480464 troglitazone results in decreased expression of SPP1 mRNA CTD PMID:19122273 troglitazone decreases expression ISO RGD:736066 6480464 troglitazone results in decreased expression of SPP1 mRNA CTD PMID:11426586 tubocurarine multiple interactions ISO RGD:736066 6480464 Tubocurarine inhibits the reaction [Nicotine results in increased expression of SPP1 protein] CTD PMID:11425648 Tungsten carbide multiple interactions ISO RGD:736066 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of SPP1 mRNA CTD PMID:18078969 uranium atom decreases secretion ISO RGD:736066 6480464 Uranium results in decreased secretion of SPP1 protein CTD PMID:21324525 uranium atom decreases expression ISO RGD:11340 6480464 Uranium results in decreased expression of SPP1 mRNA CTD PMID:31120128 urethane increases expression ISO RGD:11340 6480464 Urethane results in increased expression of SPP1 mRNA CTD PMID:16289808 urethane decreases expression ISO RGD:736066 6480464 Urethane results in decreased expression of SPP1 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:11340 6480464 Valproic Acid affects the expression of SPP1 mRNA CTD PMID:17292431 valproic acid multiple interactions ISO RGD:736066 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPP1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:736066 6480464 Valproic Acid results in increased expression of SPP1 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:736066 6480464 Valproic Acid affects the expression of SPP1 mRNA CTD PMID:25979313 valsartan multiple interactions EXP 6480464 Valsartan inhibits the reaction [AGT protein results in increased expression of SPP1 mRNA], Valsartan inhibits the reaction [AGT protein results in increased expression of SPP1 protein] CTD PMID:11115077 vanadyl sulfate multiple interactions EXP 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA] CTD PMID:16684804 vancomycin increases expression ISO RGD:11340 6480464 Vancomycin results in increased expression of SPP1 mRNA CTD PMID:18930951 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of SPP1 mRNA CTD PMID:18289764 vitamin D increases activity ISO RGD:11340 6480464 Vitamin D analog results in increased activity of SPP1 promoter CTD PMID:10777672 vitamin K multiple interactions EXP 6480464 [Warfarin co-treated with Vitamin K] results in increased expression of SPP1 mRNA CTD PMID:23117658 vorinostat increases expression ISO RGD:736066 6480464 vorinostat results in increased expression of SPP1 mRNA CTD PMID:26272509 warfarin multiple interactions ISO RGD:11340 6480464 [Warfarin co-treated with Vitamin K 1] results in increased expression of SPP1 mRNA CTD PMID:23990204 warfarin multiple interactions EXP 6480464 [Quercetin co-treated with Warfarin] results in increased expression of SPP1 mRNA, [Warfarin co-treated with Vitamin K] results in increased expression of SPP1 mRNA CTD PMID:23117658 , PMID:23223575 zinc atom multiple interactions ISO RGD:736066 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SPP1 mRNA CTD PMID:16979875 zinc atom increases expression ISO RGD:11340 6480464 Zinc deficiency results in increased expression of SPP1 mRNA CTD PMID:20857495 zinc dichloride decreases expression ISO RGD:736066 6480464 zinc chloride results in decreased expression of SPP1 mRNA CTD PMID:19428942 zinc dichloride multiple interactions ISO RGD:11340 6480464 [zinc chloride co-treated with N more ... CTD PMID:10777672 , PMID:19913120 zinc oxide decreases expression EXP 6480464 Zinc Oxide results in decreased expression of SPP1 protein CTD PMID:33205376 zinc(0) multiple interactions ISO RGD:736066 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SPP1 mRNA CTD PMID:16979875 zinc(0) increases expression ISO RGD:11340 6480464 Zinc deficiency results in increased expression of SPP1 mRNA CTD PMID:20857495
