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Gene: CENPF (centromere protein F) Homo sapiens
Symbol: CENPF
Name: centromere protein F
RGD ID: 1352971
Description: Exhibits several functions, including dynein complex binding activity; protein C-terminus binding activity; and protein homodimerization activity. Involved in several processes, including metaphase plate congression; regulation of G2/M transition of mitotic cell cycle; and ventricular system development. Localizes to several cellular components, including ciliary transition fiber; condensed chromosome outer kinetochore; and nucleus. Implicated in Stromme syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AH antigen; cell-cycle-dependent 350K nuclear protein; CENF; CENP-F kinetochore protein; centromere protein F, 350/400ka (mitosin); centromere protein F, 350/400kDa; centromere protein F, 350/400kDa (mitosin); CILD31; hcp-1; kinetochore protein CENPF; mitosin; PRO1779; STROMS
Mus musculus (house mouse) : Cenpf (centromere protein F)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cenpf (centromere protein F)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cenpf (centromere protein F)
Pan paniscus (bonobo/pygmy chimpanzee) : CENPF (centromere protein F)
Canis lupus familiaris (dog) : CENPF (centromere protein F)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cenpf (centromere protein F)
Sus scrofa (pig) : CENPF (centromere protein F)
Chlorocebus sabaeus (African green monkey) : CENPF (centromere protein F)
Heterocephalus glaber (naked mole-rat) : Cenpf (centromere protein F)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1214,603,195 - 214,664,571 (+)EnsemblGRCh38hg38GRCh38
GRCh381214,603,195 - 214,664,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371214,776,522 - 214,837,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,843,155 - 212,904,537 (+)NCBINCBI36hg18NCBI36
Build 341211,164,926 - 211,226,307NCBI
Celera1187,999,934 - 188,061,298 (+)NCBI
Cytogenetic Map1q41NCBI
HuRef1185,450,388 - 185,511,761 (+)NCBIHuRef
CHM1_11216,048,789 - 216,110,152 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CENPF
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352971
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.