Mcs8 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Mcs8 (Mammary carcinoma susceptibility QTL 8) Rattus norvegicus

Symbol: Mcs8
Name: Mammary carcinoma susceptibility QTL 8
RGD ID: 70195
Trait: mammary gland integrity trait   (VT:0010552)    
Measurement Type: mammary tumor number   (CMO:0000343)    
LOD Score: 4.28
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8143,957,878 - 24,886,169RGD_MAPPER_PIPELINE
mRatBN7.2143,813,074 - 24,531,477RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0144,833,233 - 26,466,248RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0144,830,815 - 26,295,128RGDRnor5.0
RGSC_v3.4144,895,894 - 26,416,791RGDRGSC3.4
RGSC_v3.1144,895,895 - 26,416,802RGD
Cross Type: Not Available
Strains Crossed: WKY/NHsd WF/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8RatExperimental Mammary Neoplasms  IDA 62417 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8Ratincreased mammary adenocarcinoma incidence  QTM 62417 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8Ratmammary tumor number  IDA 62417 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8Rat7,12-dimethyltetraphene  IDA 62417 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8Ratin vivo visual assessment  IDA 62417 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8RatWF/NHsd  IEA 62417 RGD 
Mcs8RatWKY/NHsd  IEA 62417 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mcs8Ratmammary gland integrity trait  IDA 62417 RGD 


#
Reference Title
Reference Citation
1. Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat. Lan H, etal., Genetics 2001 Jan;157(1):331-9.
2. QTL Data Transfer QTL data import from the RatMap database
3. The rat oncogenome: comparative genetics and genomics of rat models of mammary carcinogenesis. Shull JD Breast Dis. 2007;28:69-86.


1 to 20 of 326 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1592829Zfp326zinc finger protein 3261439412103980419Rat
41153909LOC120096556uncharacterized LOC1200965561440160024024309Rat
1309601Lrrc8dleucine rich repeat containing 8 VRAC subunit D1440299714134922Rat
1306585Lrrc8cleucine rich repeat containing 8 VRAC subunit C1442239014315590Rat
41089131LOC120096783small nucleolar RNA SNORA36 family1443119194312050Rat
11466948LOC108352696uncharacterized LOC1083526961443239154325615Rat
1563429Lrrc8bleucine rich repeat containing 8 VRAC subunit B1443504624416336Rat
11381376LOC108352839uncharacterized LOC1083528391444397084444361Rat
7646169Gbp6-ps3guanylate binding protein 6, pseudogene 31444740874708888Rat
1359703Abcg3l2ATP-binding cassette, subfamily G (WHITE), member 3-like 21444932594538264Rat
1588538Abcg3l4ATP-binding cassette, subfamily G (WHITE), member 3-like 41445452064590223Rat
41202894LOC120096559uncharacterized LOC1200965591445855044587305Rat
41393193LOC120096739U6 spliceosomal RNA1446326424632748Rat
2325094Gbp6-ps1guanylate binding protein 6, pseudogene 11446617844678989Rat
1587144Ube2v1l1ubiquitin conjugating enzyme E2 V1 like 11447032434704962Rat
1561523Gbp6guanylate binding protein family member 61447302864756508Rat
1565568Abcg3ATP-binding cassette, subfamily G (WHITE), member 31447635524839061Rat
41307086LOC120096745U6 spliceosomal RNA1447980324798138Rat
41193840LOC120096854small nucleolar RNA U31448159744816072Rat
41113676LOC120096558uncharacterized LOC1200965581448326074841231Rat

1 to 20 of 326 rows
1 to 20 of 394 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10113D14Mit2186141759357517593761Ratregion
10135D14Wox11123141762256217622685Ratregion
10622D14Mgh3125141863134518631470Ratregion
10623D14Wox12189141864404318644232Ratregion
11077D14Wox18147141730012517300272Ratregion
11078D14Mgh10227141730006917300296Ratregion
33937D14Mit111401438570383857178Ratregion
33953D14Mit1190141103062211030812Ratregion
34479D14Mgh7112141025455610254668Ratregion
11482D14Wox13194141984803919848270Ratregion
11482D14Wox13194141985881119859012Ratregion
11483D14Wox17141985879219859003Ratregion
33551D14Mit6193141827449818274691Ratregion
36053D14Rat41341481706688170790Ratregion
37350D14Rat42242141280020012800448Ratregion
37030D14Rat31711490888099088978Ratregion
36520D14Rat7174142283307822833252Ratregion
36536D14Rat11421438130743813216Ratregion
35805D14Rat5150141027701610277166Ratregion
35965D14Rat6174141487516814875342Ratregion
1 to 20 of 394 rows

Flank 1: (D14Rat1)
Rat AssemblyChrPosition (strand)Source
GRCr8143,957,878 - 3,958,020 (+)Marker Load Pipeline
mRatBN7.2143,813,074 - 3,813,216 (+)MAPPER
Rnor_6.0144,833,233 - 4,833,374NCBI
Rnor_5.0144,830,815 - 4,830,956UniSTS
RGSC_v3.4144,895,895 - 4,896,036UniSTS
RGSC_v3.4144,895,894 - 4,896,036RGD
RGSC_v3.1144,895,895 - 4,896,036RGD
Celera143,806,493 - 3,806,634UniSTS
RH 3.4 Map1475.7RGD
RH 3.4 Map1475.7UniSTS
RH 2.0 Map1490.7RGD
SHRSP x BN Map142.29RGD
FHH x ACI Map141.33RGD
Peak: (D14Wox3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21421,379,546 - 21,379,735 (-)MAPPER
Rnor_6.01424,129,442 - 24,129,630NCBI
Rnor_5.01423,966,305 - 23,966,493UniSTS
RGSC_v3.41423,002,588 - 23,002,775RGD
RGSC_v3.41423,002,587 - 23,002,775UniSTS
RGSC_v3.11423,002,588 - 23,002,775RGD
Celera1420,870,411 - 20,870,601UniSTS
RH 3.4 Map14245.5UniSTS
RH 3.4 Map14245.5RGD
Cytogenetic Map14p21UniSTS
Flank 2: (D14Rat99)
Rat AssemblyChrPosition (strand)Source
GRCr81424,885,922 - 24,886,169 (+)Marker Load Pipeline
mRatBN7.21424,531,230 - 24,531,477 (+)MAPPER
Rnor_6.01426,466,002 - 26,466,248NCBI
Rnor_5.01426,294,882 - 26,295,128UniSTS
RGSC_v3.41426,416,544 - 26,416,791RGD
RGSC_v3.41426,416,545 - 26,416,791UniSTS
RGSC_v3.11426,416,496 - 26,416,802RGD
Celera1423,936,003 - 23,936,249UniSTS
FHH x ACI Map1426.1499RGD
FHH x ACI Map1426.1499UniSTS


1 to 10 of 27 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14121760611030812Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat

1 to 10 of 27 rows


Database
Acc Id
Source(s)
NCBI Gene Mcs8

Note Type Note Reference