Pf4 (platelet factor 4) - Rat Genome Database

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Gene: Pf4 (platelet factor 4) Rattus norvegicus
Symbol: Pf4
Name: platelet factor 4
RGD ID: 3305
Description: Predicted to enable CXCR3 chemokine receptor binding activity; chemokine activity; and heparin binding activity. Involved in immune response and protein-containing complex assembly. Located in platelet alpha granule. Part of protein-containing complex. Orthologous to several human genes including PF4 (platelet factor 4); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Cxcl4; PF-4; Pf4a; RATPF4A
RGD Orthologs
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21417,298,438 - 17,299,148 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,298,308 - 17,299,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,298,559 - 17,299,267 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01418,617,480 - 18,618,188 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01417,309,831 - 17,310,539 (-)NCBIRnor_WKY
Rnor_6.01418,848,549 - 18,849,258 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,848,549 - 18,849,258 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,758,191 - 18,758,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,812,550 - 18,813,259 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11418,813,312 - 18,815,140 (-)NCBI
Celera1416,674,419 - 16,675,127 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
barium sulfate  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoic acid  (ISO)
beta-naphthoflavone  (EXP)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
C60 fullerene  (EXP)
cangrelor  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
ceric oxide  (EXP)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (EXP)
cobalt atom  (ISO)
cocaine  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dichloromethane  (EXP)
diethyl malate  (ISO)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethylbenzene  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fructose  (ISO)
furan  (EXP)
furosemide  (EXP)
genistein  (ISO)
glucose  (ISO)
griseofulvin  (ISO)
heparin  (ISO)
hydrogen cyanide  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
isobutyl nitrite  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
melatonin  (ISO)
methotrexate  (ISO)
mifepristone  (EXP)
N-nitrosodiethylamine  (EXP)
naphthalene  (ISO)
neoechinulin A  (ISO)
nickel atom  (ISO)
nortriptyline  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paroxetine  (ISO)
phenformin  (EXP)
poly(styrene)  (ISO)
potassium cyanide  (ISO)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
rebaudioside A  (ISO)
resveratrol  (EXP)
sertraline  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sterigmatocystin  (ISO)
steviol  (ISO)
stevioside  (ISO)
succimer  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
verapamil  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Immunogold probing of platelet factor 4 in different ploidy classes of rat megakaryocytes sorted by flow cytometry. Hegyi E, etal., Exp Hematol. 1990 Aug;18(7):789-93.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Gene expression changes in the retina after systemic administration of aldosterone. Ono A, etal., Jpn J Ophthalmol. 2018 Jul;62(4):499-507. doi: 10.1007/s10384-018-0595-4. Epub 2018 Apr 30.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Biochemical characterization of the serum fetuin-mineral complex. Price PA, etal., J Biol Chem. 2003 Jun 13;278(24):22153-60. Epub 2003 Apr 3.
9. Transcriptional regulation of the rat platelet factor 4 gene: interaction between an enhancer/silencer domain and the GATA site. Ravid K, etal., Mol Cell Biol 1991 Dec;11(12):6116-27.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Platelet factor 4 fragment induces histamine release from rat peritoneal mast cells. Suzuki R, etal., Peptides 2002 Oct;23(10):1713-7.
14. Chemokine and chemokine receptor expression during colony stimulating factor-1-induced osteoclast differentiation in the toothless osteopetrotic rat: a key role for CCL9 (MIP-1gamma) in osteoclastogenesis in vivo and in vitro. Yang M, etal., Blood. 2006 Mar 15;107(6):2262-70. doi: 10.1182/blood-2005-08-3365. Epub 2005 Nov 22.
Additional References at PubMed
PMID:1688470   PMID:2140694   PMID:3821732   PMID:6945600   PMID:8033893   PMID:9531587   PMID:10666185   PMID:10877842   PMID:11685038   PMID:12041672   PMID:12609849   PMID:12782716  
PMID:15187018   PMID:16797058   PMID:17244792   PMID:22206666   PMID:23245326   PMID:28053995  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21417,298,438 - 17,299,148 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,298,308 - 17,299,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,298,559 - 17,299,267 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01418,617,480 - 18,618,188 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01417,309,831 - 17,310,539 (-)NCBIRnor_WKY
Rnor_6.01418,848,549 - 18,849,258 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,848,549 - 18,849,258 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,758,191 - 18,758,900 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,812,550 - 18,813,259 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11418,813,312 - 18,815,140 (-)NCBI
Celera1416,674,419 - 16,675,127 (-)NCBICelera
Cytogenetic Map14p22NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38473,980,811 - 73,982,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl473,980,811 - 73,982,027 (-)EnsemblGRCh38hg38GRCh38
GRCh37474,846,528 - 74,847,841 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,065,660 - 75,066,541 (-)NCBINCBI36Build 36hg18NCBI36
Build 34475,211,830 - 75,212,712NCBI
Celera472,206,939 - 72,207,858 (-)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,657,501 - 70,658,800 (-)NCBIHuRef
CHM1_1474,882,437 - 74,883,736 (-)NCBICHM1_1
T2T-CHM13v2.0477,324,459 - 77,325,772 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39590,920,362 - 90,921,242 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl590,920,294 - 90,921,242 (+)EnsemblGRCm39 Ensembl
GRCm38590,772,435 - 90,773,383 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,772,435 - 90,773,383 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,201,461 - 91,202,409 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,847,713 - 91,848,583 (+)NCBIMGSCv36mm8
Celera588,924,056 - 88,925,004 (+)NCBICelera
Cytogenetic Map5E1NCBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1456,265,831 - 56,267,756 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0450,208,806 - 50,210,570 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1456,041,833 - 56,043,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,041,833 - 56,043,750 (+)Ensemblpanpan1.1panPan2


Variants in Pf4
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:118
Interacting mature miRNAs:125
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14381307418274691Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,300,125 - 17,300,272 (+)MAPPERmRatBN7.2
Rnor_6.01418,850,235 - 18,850,381NCBIRnor6.0
Rnor_5.01418,759,877 - 18,760,023UniSTSRnor5.0
RGSC_v3.41418,814,236 - 18,814,382UniSTSRGSC3.4
Celera1416,676,104 - 16,676,250UniSTS
Cytogenetic Map14p22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,300,069 - 17,300,296 (+)MAPPERmRatBN7.2
Rnor_6.01418,850,179 - 18,850,405NCBIRnor6.0
Rnor_5.01418,759,821 - 18,760,047UniSTSRnor5.0
RGSC_v3.41418,814,179 - 18,814,406RGDRGSC3.4
RGSC_v3.41418,814,180 - 18,814,406UniSTSRGSC3.4
RGSC_v3.11418,814,179 - 18,814,406RGD
Celera1416,676,048 - 16,676,274UniSTS
RH 3.4 Map14213.6UniSTS
RH 3.4 Map14213.6RGD
RH 2.0 Map14215.5RGD
Cytogenetic Map14p22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,299,244 - 17,299,529 (+)MAPPERmRatBN7.2
Rnor_6.01418,849,355 - 18,849,638NCBIRnor6.0
Rnor_5.01418,758,997 - 18,759,280UniSTSRnor5.0
RGSC_v3.41418,813,355 - 18,813,639RGDRGSC3.4
RGSC_v3.41418,813,356 - 18,813,639UniSTSRGSC3.4
RGSC_v3.11418,813,355 - 18,813,639RGD
Celera1416,675,224 - 16,675,507UniSTS
SHRSP x BN Map146.9UniSTS
SHRSP x BN Map146.9RGD
Cytogenetic Map14p22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,298,308 - 17,298,460 (+)MAPPERmRatBN7.2
Rnor_6.01418,848,420 - 18,848,571NCBIRnor6.0
Rnor_5.01418,758,062 - 18,758,213UniSTSRnor5.0
RGSC_v3.41418,812,421 - 18,812,572UniSTSRGSC3.4
Celera1416,674,290 - 16,674,441UniSTS
Cytogenetic Map14p22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,298,493 - 17,298,715 (+)MAPPERmRatBN7.2
Rnor_6.01418,848,605 - 18,848,825NCBIRnor6.0
Rnor_5.01418,758,247 - 18,758,467UniSTSRnor5.0
RGSC_v3.41418,812,606 - 18,812,826UniSTSRGSC3.4
Celera1416,674,475 - 16,674,694UniSTS
Cytogenetic Map14p22UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21417,298,700 - 17,299,140 (+)MAPPERmRatBN7.2
Rnor_6.01418,848,811 - 18,849,250NCBIRnor6.0
Rnor_5.01418,758,453 - 18,758,892UniSTSRnor5.0
RGSC_v3.41418,812,812 - 18,813,251UniSTSRGSC3.4
Celera1416,674,680 - 16,675,119UniSTS
Cytogenetic Map14p22UniSTS


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 4 4 4
Medium 3 41 22 21 12 21 1 2 37 21 32 11 1
Low 2 31 16 7 16 7 9 37 14 9 7
Below cutoff


Reference Sequences
RefSeq Acc Id: ENSRNOT00000033406   ⟹   ENSRNOP00000032276
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1417,298,308 - 17,299,365 (-)Ensembl
Rnor_6.0 Ensembl1418,848,549 - 18,849,258 (-)Ensembl
RefSeq Acc Id: NM_001007729   ⟹   NP_001007730
RefSeq Status: VALIDATED
Rat AssemblyChrPosition (strand)Source
mRatBN7.21417,298,438 - 17,299,148 (-)NCBI
Rnor_6.01418,848,549 - 18,849,258 (-)NCBI
Rnor_5.01418,758,191 - 18,758,900 (-)NCBI
RGSC_v3.41418,812,550 - 18,813,259 (-)RGD
Celera1416,674,419 - 16,675,127 (-)RGD
Protein Sequences
Protein RefSeqs NP_001007730 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41832 (Get FASTA)   NCBI Sequence Viewer  
  EDL88566 (Get FASTA)   NCBI Sequence Viewer  
  EDL88567 (Get FASTA)   NCBI Sequence Viewer  
  EDL88568 (Get FASTA)   NCBI Sequence Viewer  
  P06765 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001007730   ⟸   NM_001007729
- Peptide Label: precursor
- UniProtKB: P06765 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032276   ⟸   ENSRNOT00000033406

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06765-F1-model_v2 AlphaFold P06765 1-105 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699229
Promoter ID:EPDNEW_R9752
Type:multiple initiation site
Description:platelet factor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Rat AssemblyChrPosition (strand)Source
Rnor_6.01418,849,331 - 18,849,391EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3305 AgrOrtholog
BioCyc Gene G2FUF-16205 BioCyc
Ensembl Genes ENSRNOG00000028015 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000032276 ENTREZGENE
  ENSRNOP00000032276.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000033406 ENTREZGENE
  ENSRNOT00000033406.2 UniProtKB/Swiss-Prot
Gene3D-CATH UniProtKB/Swiss-Prot
InterPro Chemokine_CXC UniProtKB/Swiss-Prot
  Chemokine_CXC_CS UniProtKB/Swiss-Prot
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot
  CXC_Chemokine_domain UniProtKB/Swiss-Prot
  Interleukin_8-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:360918 UniProtKB/Swiss-Prot
PANTHER PTHR10179 UniProtKB/Swiss-Prot
  PTHR10179:SF43 UniProtKB/Swiss-Prot
Pfam IL8 UniProtKB/Swiss-Prot
PhenoGen Pf4 PhenoGen
SMART SCY UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot
UniProt P06765 ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-19 Pf4  platelet factor 4  Cxcl4  chemokine (C-X-C motif) ligand 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cxcl4  chemokine (C-X-C motif) ligand 4  Pf4  platelet factor 4  Symbol and Name updated 1299863 APPROVED
2002-06-10 Pf4  Platelet factor 4      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process induces histamine release from peritoneal mast cells 724612