1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in increased expression of PF4 mRNA CTD PMID:27840820 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:735658 6480464 Dinitrochlorobenzene results in increased expression of PF4 mRNA CTD PMID:19647056 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PF4 mRNA CTD PMID:11752688 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PF4 mRNA CTD PMID:20059583 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735658 6480464 Tetrachlorodibenzodioxin results in increased expression of PF4 mRNA CTD PMID:21041162 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735658 6480464 [Bucladesine co-treated with Tetrachlorodibenzodioxin] results in increased expression of PF4 mRNA more ... CTD PMID:21979172 , PMID:24582691 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PF4 mRNA CTD PMID:21346803 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases expression ISO RGD:735657 6480464 Verapamil results in decreased expression of PF4 protein CTD PMID:2962587 2-hydroxypropanoic acid increases expression ISO RGD:735657 6480464 Lactic Acid results in increased expression of PF4 mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329 3-methylcholanthrene multiple interactions ISO RGD:735658 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PF4 mRNA CTD PMID:25926378 4,4'-diaminodiphenylmethane decreases expression ISO RGD:735658 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of PF4 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:735658 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of PF4 mRNA CTD PMID:30951980 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:735658 6480464 Oxazolone results in increased expression of PF4 mRNA CTD PMID:19647056 4-hydroxyphenyl retinamide decreases expression ISO RGD:735658 6480464 Fenretinide results in decreased expression of PF4 mRNA CTD PMID:28973697 acetylsalicylic acid multiple interactions ISO RGD:735657 6480464 Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of PF4 protein] CTD PMID:17303692 acrolein increases expression ISO RGD:735658 6480464 Acrolein results in increased expression of PF4 protein CTD PMID:20678513 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of PF4 mRNA CTD PMID:28959563 ADP increases secretion ISO RGD:735657 6480464 Adenosine Diphosphate results in increased secretion of PF4 protein CTD PMID:19428933 aflatoxin B1 increases expression ISO RGD:735658 6480464 Aflatoxin B1 results in increased expression of PF4 mRNA CTD PMID:19770486 aflatoxin B1 decreases methylation ISO RGD:735657 6480464 Aflatoxin B1 results in decreased methylation of PF4 gene CTD PMID:27153756 aldehydo-D-glucose increases expression ISO RGD:735657 6480464 Glucose results in increased expression of PF4 mRNA CTD PMID:31655124 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PF4 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:735657 6480464 Antirheumatic Agents results in decreased expression of PF4 mRNA CTD PMID:24449571 Aroclor 1254 increases expression ISO RGD:735658 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of PF4 mRNA CTD PMID:23650126 Aroclor 1254 multiple interactions ISO RGD:735658 6480464 [Chlorodiphenyl (54% Chlorine) co-treated with Tetrachlorodibenzodioxin] results in increased expression of PF4 CTD PMID:24582691 arsane affects expression ISO RGD:735657 6480464 Arsenic affects the expression of PF4 protein CTD PMID:24675094 arsenic atom affects expression ISO RGD:735657 6480464 Arsenic affects the expression of PF4 protein CTD PMID:24675094 barium sulfate increases expression EXP 6480464 Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 benzene affects expression ISO RGD:735657 6480464 Benzene affects the expression of PF4 mRNA CTD PMID:17119257 benzene decreases expression ISO RGD:735657 6480464 Benzene results in decreased expression of PF4 mRNA, Benzene results in decreased expression of PF4 protein CTD PMID:15929907 , PMID:16286641 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of PF4 mRNA CTD PMID:21839799 benzo[a]pyrene affects methylation ISO RGD:735657 6480464 Benzo(a)pyrene affects the methylation of PF4 exon, Benzo(a)pyrene affects the methylation of PF4 promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:735658 6480464 Benzo(a)pyrene results in increased expression of PF4 mRNA CTD PMID:22228805 benzoic acid multiple interactions ISO RGD:735657 6480464 Benzoic Acid analog inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased secretion of PF4 protein] CTD PMID:22273509 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PF4 mRNA CTD PMID:18164116 bexarotene increases expression EXP 6480464 bexarotene results in increased expression of PF4 mRNA CTD PMID:17630414 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PF4 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PF4 mRNA CTD PMID:34947998 bisphenol A decreases expression ISO RGD:735658 6480464 bisphenol A results in decreased expression of PF4 mRNA CTD PMID:26911702 bisphenol F increases expression ISO RGD:735658 6480464 bisphenol F results in increased expression of PF4 mRNA CTD PMID:30951980 bucladesine increases expression ISO RGD:735658 6480464 Bucladesine results in increased expression of PF4 mRNA CTD PMID:21979172 bucladesine multiple interactions ISO RGD:735658 6480464 [Bucladesine co-treated with Tetrachlorodibenzodioxin] results in increased expression of PF4 mRNA CTD PMID:21979172 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of PF4 mRNA CTD PMID:19167457 cangrelor multiple interactions ISO RGD:735657 6480464 cangrelor inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased secretion of PF4 protein] CTD PMID:22273509 carbon nanotube multiple interactions ISO RGD:735658 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PF4 mRNA CTD PMID:25926378 carbonyl sulfide increases expression EXP 6480464 carbonyl sulfide results in increased expression of PF4 mRNA CTD PMID:19395590 ceric oxide increases expression EXP 6480464 ceric oxide results in increased expression of PF4 mRNA CTD PMID:29463257 CGP 52608 multiple interactions ISO RGD:735657 6480464 CGP 52608 promotes the reaction [RORA protein binds to PF4 gene] CTD PMID:28238834 choline multiple interactions ISO RGD:735658 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PF4 mRNA CTD PMID:20938992 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PF4 mRNA CTD PMID:22023808 cobalt atom multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329 cocaine increases expression ISO RGD:735657 6480464 Cocaine results in increased expression of PF4 protein CTD PMID:10814631 D-glucose increases expression ISO RGD:735657 6480464 Glucose results in increased expression of PF4 mRNA CTD PMID:31655124 dexamethasone increases expression ISO RGD:735658 6480464 Dexamethasone results in increased expression of PF4 mRNA CTD PMID:21041162 dexamethasone multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329 dextran sulfate multiple interactions ISO RGD:735658 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PF4 mRNA CTD PMID:29950665 dichloromethane decreases expression EXP 6480464 Methylene Chloride results in decreased expression of PF4 mRNA CTD PMID:20955722 diethyl malate affects expression ISO RGD:735658 6480464 diethyl malate affects the expression of PF4 mRNA CTD PMID:24814887 diethylstilbestrol increases expression ISO RGD:735658 6480464 Diethylstilbestrol results in increased expression of PF4 mRNA CTD PMID:21041162 doxorubicin multiple interactions ISO RGD:735658 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of PF4 mRNA CTD PMID:21040762 doxorubicin decreases expression ISO RGD:735657 6480464 Doxorubicin results in decreased expression of PF4 mRNA CTD PMID:29803840 doxorubicin decreases expression ISO RGD:735658 6480464 Doxorubicin results in decreased expression of PF4 mRNA CTD PMID:25896364 entinostat decreases expression ISO RGD:735657 6480464 entinostat results in decreased expression of PF4 mRNA CTD PMID:27188386 ethylbenzene decreases expression EXP 6480464 ethylbenzene results in decreased expression of PF4 mRNA CTD PMID:20955722 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of PF4 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:735658 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PF4 mRNA CTD PMID:20938992 fructose increases expression ISO RGD:735657 6480464 Fructose results in increased expression of PF4 mRNA CTD PMID:31655124 furan decreases expression EXP 6480464 furan results in decreased expression of PF4 mRNA CTD PMID:26194646 furosemide decreases expression EXP 6480464 Furosemide results in decreased expression of PF4 mRNA CTD PMID:16526316 genistein decreases expression ISO RGD:735658 6480464 Genistein results in decreased expression of PF4 mRNA CTD PMID:32186404 glucose increases expression ISO RGD:735657 6480464 Glucose results in increased expression of PF4 mRNA CTD PMID:31655124 griseofulvin affects expression ISO RGD:735658 6480464 Griseofulvin affects the expression of PF4 mRNA CTD PMID:12735108 heparin affects binding ISO RGD:735657 6480464 [Heparin binds to PF4 protein] which binds to FCGR2A protein, Heparin binds to PF4 protein CTD PMID:20162249 , PMID:8282825 heparin increases secretion ISO RGD:735657 6480464 Heparin results in increased secretion of PF4 protein CTD PMID:2437338 , PMID:2709525 hydrogen cyanide increases expression ISO RGD:735658 6480464 Hydrogen Cyanide results in increased expression of PF4 mRNA CTD PMID:33914522 hydroquinone O-beta-D-glucopyranoside decreases expression ISO RGD:735657 6480464 Arbutin results in decreased expression of PF4 mRNA CTD PMID:17103032 isobutyl nitrite increases expression ISO RGD:735658 6480464 isobutyl nitrite results in increased expression of PF4 mRNA CTD PMID:16288974 L-methionine multiple interactions ISO RGD:735658 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of PF4 mRNA CTD PMID:20938992 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of PF4 mRNA CTD PMID:35283115 lipopolysaccharide increases expression ISO RGD:735657 6480464 Lipopolysaccharides results in increased expression of PF4 mRNA, Lipopolysaccharides results in increased expression of PF4 protein CTD PMID:15788441 lipopolysaccharide increases expression ISO RGD:735658 6480464 Lipopolysaccharides results in increased expression of PF4 mRNA CTD PMID:21979172 lipopolysaccharide multiple interactions ISO RGD:735658 6480464 [Lipopolysaccharides co-treated with Melatonin] results in increased expression of PF4 mRNA CTD PMID:21461237 melatonin multiple interactions ISO RGD:735658 6480464 [Lipopolysaccharides co-treated with Melatonin] results in increased expression of PF4 mRNA CTD PMID:21461237 methotrexate decreases expression ISO RGD:735657 6480464 Methotrexate results in decreased expression of PF4 mRNA CTD PMID:17400583 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of PF4 mRNA CTD PMID:25972201 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PF4 mRNA CTD PMID:18164116 naphthalene increases expression ISO RGD:735658 6480464 naphthalene results in increased expression of PF4 mRNA CTD PMID:18978301 neoechinulin A increases expression ISO RGD:735658 6480464 neoechinulin A results in increased expression of PF4 mRNA CTD PMID:19818335 nickel atom multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329 nortriptyline affects expression ISO RGD:735657 6480464 Nortriptyline affects the expression of PF4 protein CTD PMID:10770450 ozone multiple interactions ISO RGD:735658 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PF4 mRNA CTD PMID:34911549 paracetamol affects expression ISO RGD:735658 6480464 Acetaminophen affects the expression of PF4 mRNA CTD PMID:17562736 paroxetine decreases expression ISO RGD:735657 6480464 Paroxetine results in decreased expression of PF4 protein CTD PMID:10770450 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of PF4 mRNA CTD PMID:31324951 poly(styrene) increases secretion ISO RGD:735657 6480464 styrofoam analog results in increased secretion of PF4 protein CTD PMID:19428933 potassium cyanide decreases expression ISO RGD:735658 6480464 Potassium Cyanide results in decreased expression of PF4 mRNA CTD PMID:33914522 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of PF4 mRNA CTD PMID:27225895 pravastatin decreases expression ISO RGD:735658 6480464 Pravastatin results in decreased expression of PF4 mRNA CTD PMID:27225895 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:735658 6480464 NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of PF4 mRNA] CTD PMID:22698814 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:735658 6480464 Pregnenolone Carbonitrile results in decreased expression of PF4 mRNA CTD PMID:22698814 rac-lactic acid increases expression ISO RGD:735657 6480464 Lactic Acid results in increased expression of PF4 mRNA CTD PMID:30851411 rebaudioside A increases expression ISO RGD:735657 6480464 rebaudioside A results in increased expression of PF4 mRNA CTD PMID:31655124 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of PF4 mRNA CTD PMID:19228061 sertraline decreases expression ISO RGD:735657 6480464 Sertraline results in decreased expression of PF4 protein CTD PMID:15932816 silicon dioxide decreases expression ISO RGD:735657 6480464 Silicon Dioxide analog results in decreased expression of PF4 mRNA CTD PMID:25895662 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of PF4 mRNA CTD PMID:22431001 sodium arsenate increases expression ISO RGD:735658 6480464 sodium arsenate results in increased expression of PF4 mRNA CTD PMID:30953684 sodium arsenite increases expression ISO RGD:735658 6480464 sodium arsenite results in increased expression of PF4 mRNA CTD PMID:21911445 Soman increases expression EXP 6480464 Soman results in increased expression of PF4 mRNA CTD PMID:19281266 sterigmatocystin increases expression ISO RGD:735658 6480464 Sterigmatocystin results in increased expression of PF4 mRNA CTD PMID:19818335 steviol increases expression ISO RGD:735657 6480464 steviol results in increased expression of PF4 mRNA CTD PMID:31655124 stevioside increases expression ISO RGD:735657 6480464 stevioside results in increased expression of PF4 mRNA CTD PMID:31655124 succimer multiple interactions ISO RGD:735658 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of PF4 mRNA CTD PMID:26378955 testosterone increases expression ISO RGD:735658 6480464 Testosterone deficiency results in increased expression of PF4 mRNA CTD PMID:33848595 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PF4 mRNA CTD PMID:16239168 tetrachloromethane increases expression ISO RGD:735658 6480464 Carbon Tetrachloride results in increased expression of PF4 mRNA CTD PMID:27339419 , PMID:31919559 titanium dioxide multiple interactions ISO RGD:735658 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PF4 mRNA CTD PMID:29950665 toluene 2,4-diisocyanate increases expression ISO RGD:735658 6480464 Toluene 2, 4-Diisocyanate results in increased expression of PF4 mRNA CTD PMID:19647056 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of PF4 mRNA CTD PMID:20955722 troglitazone increases expression ISO RGD:735658 6480464 troglitazone results in increased expression of PF4 mRNA CTD PMID:28973697 valproic acid affects expression ISO RGD:735657 6480464 Valproic Acid affects the expression of PF4 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:735657 6480464 Valproic Acid results in increased expression of PF4 mRNA CTD PMID:24383497 , PMID:24935251 verapamil decreases expression ISO RGD:735657 6480464 Verapamil results in decreased expression of PF4 protein CTD PMID:2962587 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of PF4 mRNA CTD PMID:19015723 zidovudine multiple interactions ISO RGD:735657 6480464 [Zidovudine co-treated with IFNA1 protein] results in increased expression of PF4 mRNA CTD PMID:20370541 zinc atom multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329 zinc(0) multiple interactions ISO RGD:735658 6480464 [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PF4 mRNA] CTD PMID:23503329