Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Slc10a6 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SLC10A6 mRNA | CTD | PMID:22206623 | Slc10a6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC10A6 mRNA | CTD | PMID:32109520 | Slc10a6 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC10A6 mRNA | CTD | PMID:34747641 | Slc10a6 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SLC10A6 mRNA | CTD | PMID:28973697 | Slc10a6 | Rat | aflatoxin B1 | decreases methylation | ISO | SLC10A6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SLC10A6 exon | CTD | PMID:30157460 | Slc10a6 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of SLC10A6 mRNA | CTD | PMID:30779732 | Slc10a6 | Rat | arsane | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Arsenic results in decreased expression of SLC10A6 mRNA | CTD | PMID:19654921 | Slc10a6 | Rat | arsenic atom | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Arsenic results in decreased expression of SLC10A6 mRNA | CTD | PMID:19654921 | Slc10a6 | Rat | arsenite(3-) | increases expression | ISO | SLC10A6 (Homo sapiens) | 6480464 | arsenite metabolite results in increased expression of SLC10A6 mRNA | CTD | PMID:33129825 | Slc10a6 | Rat | benzo[a]pyrene | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SLC10A6 mRNA | CTD | PMID:21569818 | Slc10a6 | Rat | benzo[a]pyrene | affects methylation | ISO | SLC10A6 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC10A6 promoter | CTD | PMID:27901495 | Slc10a6 | Rat | benzo[a]pyrene | increases methylation | ISO | SLC10A6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SLC10A6 5' UTR | CTD | PMID:27901495 | Slc10a6 | Rat | benzo[b]fluoranthene | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in decreased expression of SLC10A6 mRNA | CTD | PMID:26377693 | Slc10a6 | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of SLC10A6 mRNA | CTD | PMID:26377693 | Slc10a6 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC10A6 mRNA | CTD | PMID:25181051 more ... | Slc10a6 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of SLC10A6 mRNA | CTD | PMID:32479839 | Slc10a6 | Rat | buta-1,3-diene | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | 1 and 3-butadiene results in increased expression of SLC10A6 mRNA | CTD | PMID:29038090 | Slc10a6 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of SLC10A6 promoter | CTD | PMID:22457795 | Slc10a6 | Rat | carbon nanotube | affects expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Nanotubes and Carbon analog affects the expression of SLC10A6 mRNA | CTD | PMID:25554681 | Slc10a6 | Rat | carbon nanotube | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of SLC10A6 mRNA | CTD | PMID:25554681 and PMID:25620056 | Slc10a6 | Rat | CGP 52608 | multiple interactions | ISO | SLC10A6 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC10A6 gene] | CTD | PMID:28238834 | Slc10a6 | Rat | chloroprene | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Chloroprene results in increased expression of SLC10A6 mRNA | CTD | PMID:23125180 | Slc10a6 | Rat | chlorpyrifos | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SLC10A6 mRNA | CTD | PMID:32715474 | Slc10a6 | Rat | clobetasol | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Clobetasol results in increased expression of SLC10A6 mRNA | CTD | PMID:27462272 | Slc10a6 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of SLC10A6 mRNA | CTD | PMID:27523638 | Slc10a6 | Rat | daidzein | multiple interactions | ISO | SLC10A6 (Homo sapiens) | 6480464 | daidzein inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate] more ... | CTD | PMID:25319728 | Slc10a6 | Rat | daidzein | increases transport | ISO | SLC10A6 (Homo sapiens) | 6480464 | SLC10A6 protein results in increased transport of daidzein metabolite | CTD | PMID:25319728 | Slc10a6 | Rat | dehydroepiandrosterone sulfate | increases transport | ISO | Slc10a6 (Mus musculus) | 6480464 | SLC10A6 protein results in increased transport of Dehydroepiandrosterone Sulfate | CTD | PMID:23562556 | Slc10a6 | Rat | dexamethasone | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of SLC10A6 mRNA | CTD | PMID:22733784 | Slc10a6 | Rat | dextran sulfate | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC10A6 mRNA | CTD | PMID:29950665 | Slc10a6 | Rat | diclofenac | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Diclofenac results in increased expression of SLC10A6 mRNA | CTD | PMID:26934552 | Slc10a6 | Rat | dimethylarsinic acid | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of SLC10A6 mRNA | CTD | PMID:34876320 | Slc10a6 | Rat | doxorubicin | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of SLC10A6 mRNA | CTD | PMID:21040762 | Slc10a6 | Rat | doxorubicin | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of SLC10A6 mRNA | CTD | PMID:21040762 | Slc10a6 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SLC10A6 mRNA | CTD | PMID:29391264 | Slc10a6 | Rat | estrone 3-sulfate | increases transport | ISO | Slc10a6 (Mus musculus) | 6480464 | SLC10A6 protein results in increased transport of estrone sulfate | CTD | PMID:23562556 | Slc10a6 | Rat | estrone 3-sulfate | increases uptake | ISO | SLC10A6 (Homo sapiens) | 6480464 | SLC10A6 protein results in increased uptake of estrone sulfate | CTD | PMID:30186172 | Slc10a6 | Rat | estrone 3-sulfate | increases response to substance | ISO | SLC10A6 (Homo sapiens) | 6480464 | SLC10A6 protein results in increased susceptibility to estrone sulfate | CTD | PMID:30186172 | Slc10a6 | Rat | estrone 3-sulfate | multiple interactions | ISO | SLC10A6 (Homo sapiens) | 6480464 | daidzein inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate] more ... | CTD | PMID:25319728 and PMID:30186172 | Slc10a6 | Rat | estrone 3-sulfate | increases transport | ISO | SLC10A6 (Homo sapiens) | 6480464 | SLC10A6 protein results in increased transport of estrone sulfate | CTD | PMID:25319728 | Slc10a6 | Rat | Genipin | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC10A6 mRNA] | CTD | PMID:22687549 | Slc10a6 | Rat | genistein | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Genistein results in decreased expression of SLC10A6 mRNA | CTD | PMID:32186404 | Slc10a6 | Rat | hydrogen cyanide | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Hydrogen Cyanide results in increased expression of SLC10A6 mRNA | CTD | PMID:33914522 | Slc10a6 | Rat | Indeno[1,2,3-cd]pyrene | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | indeno(1 more ... | CTD | PMID:26377693 | Slc10a6 | Rat | isoprenaline | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of SLC10A6 mRNA | CTD | PMID:20003209 | Slc10a6 | Rat | lidocaine | increases expression | EXP | | 6480464 | Lidocaine results in increased expression of SLC10A6 mRNA | CTD | PMID:35283115 | Slc10a6 | Rat | lipopolysaccharide | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC10A6 mRNA] | CTD | PMID:22687549 | Slc10a6 | Rat | lipopolysaccharide | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of SLC10A6 mRNA | CTD | PMID:22687549 | Slc10a6 | Rat | methylarsonic acid | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of SLC10A6 mRNA | CTD | PMID:34876320 | Slc10a6 | Rat | ozone | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SLC10A6 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of SLC10A6 mRNA | CTD | PMID:34911549 | Slc10a6 | Rat | paracetamol | affects expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SLC10A6 mRNA | CTD | PMID:17562736 | Slc10a6 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of SLC10A6 mRNA | CTD | PMID:37995155 | Slc10a6 | Rat | potassium cyanide | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of SLC10A6 mRNA | CTD | PMID:33914522 | Slc10a6 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of SLC10A6 mRNA | CTD | PMID:28903501 | Slc10a6 | Rat | pregnenolone sulfate | increases transport | ISO | Slc10a6 (Mus musculus) | 6480464 | SLC10A6 protein results in increased transport of pregnenolone sulfate | CTD | PMID:23562556 | Slc10a6 | Rat | sodium arsenate | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of SLC10A6 mRNA | CTD | PMID:34876320 | Slc10a6 | Rat | sodium arsenite | increases expression | ISO | SLC10A6 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SLC10A6 mRNA | CTD | PMID:34032870 | Slc10a6 | Rat | sodium arsenite | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SLC10A6 mRNA | CTD | PMID:37682722 | Slc10a6 | Rat | sodium arsenite | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of SLC10A6 mRNA | CTD | PMID:34876320 | Slc10a6 | Rat | sodium atom | multiple interactions | ISO | SLC10A6 (Homo sapiens) | 6480464 | Sodium promotes the reaction [SLC10A6 protein results in increased uptake of estrone sulfate] | CTD | PMID:30186172 | Slc10a6 | Rat | sulforaphane | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | sulforaphane results in decreased expression of SLC10A6 mRNA | CTD | PMID:30529165 | Slc10a6 | Rat | tamoxifen | affects expression | ISO | Slc10a6 (Mus musculus) | 6480464 | Tamoxifen affects the expression of SLC10A6 mRNA | CTD | PMID:20937368 | Slc10a6 | Rat | Theaflavin 3,3'-digallate | affects expression | ISO | SLC10A6 (Homo sapiens) | 6480464 | theaflavin-3 and 3'-digallate affects the expression of SLC10A6 mRNA | CTD | PMID:34925699 | Slc10a6 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLC10A6 mRNA | CTD | PMID:34492290 | Slc10a6 | Rat | titanium dioxide | multiple interactions | ISO | Slc10a6 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC10A6 mRNA | CTD | PMID:29950665 | Slc10a6 | Rat | titanium dioxide | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SLC10A6 mRNA | CTD | PMID:35295148 | Slc10a6 | Rat | tremolite asbestos | decreases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | tremolite results in decreased expression of SLC10A6 mRNA | CTD | PMID:29279043 | Slc10a6 | Rat | triptonide | increases expression | ISO | Slc10a6 (Mus musculus) | 6480464 | triptonide results in increased expression of SLC10A6 mRNA | CTD | PMID:33045310 | |