Sult1d1 (sulfotransferase family 1D, member 1) - Rat Genome Database

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Gene: Sult1d1 (sulfotransferase family 1D, member 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Sult1d1
Name: sulfotransferase family 1D, member 1
RGD ID: 620491
Description: Predicted to enable sulfotransferase activity. Predicted to be involved in sulfation. Predicted to be active in cytoplasm; INTERACTS WITH dexamethasone; oxycodone; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dopamine sulfotransferase Sult1d1; N-sulfotransferase; ST1D1; sulfotransferase 1 family member D1; Sult-n; Sultn; tyrosine-ester sulfotransferase
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21420,441,135 - 20,476,341 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1420,441,924 - 20,476,341 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1420,630,128 - 20,664,549 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01421,949,041 - 21,983,464 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01420,704,459 - 20,738,873 (+)NCBIRnor_WKY
Rnor_6.01422,107,418 - 22,126,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1422,091,777 - 22,126,021 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01422,022,304 - 22,040,897 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41421,983,705 - 22,002,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11421,983,712 - 22,002,744 (+)NCBI
Celera1419,860,399 - 19,879,003 (+)NCBICelera
Cytogenetic Map14p21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Information Derived from GenBank Report RGD, Sept. 2003

Genomics

Variants

.
Variants in Sult1d1
118 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:675
Count of miRNA genes:216
Interacting mature miRNAs:249
Transcripts:ENSRNOT00000060179, ENSRNOT00000072483
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat

Markers in Region
BE105744  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21420,474,973 - 20,475,124 (+)MAPPERmRatBN7.2
Rnor_6.01422,124,671 - 22,124,821NCBIRnor6.0
Rnor_5.01422,039,557 - 22,039,707UniSTSRnor5.0
RGSC_v3.41422,001,402 - 22,001,552UniSTSRGSC3.4
Celera1419,877,663 - 19,877,813UniSTS
RH 3.4 Map14283.39UniSTS
Cytogenetic Map14p21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2
Low 17 1 8 1 32 14 2
Below cutoff 3 2 5 5 5 4 4 39 10 12 7 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000060179   ⟹   ENSRNOP00000056924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1422,107,416 - 22,126,011 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072483   ⟹   ENSRNOP00000066303
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1420,441,924 - 20,476,341 (+)Ensembl
Rnor_6.0 Ensembl1422,091,777 - 22,126,021 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080114   ⟹   ENSRNOP00000072150
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1422,107,427 - 22,124,786 (+)Ensembl
RefSeq Acc Id: NM_021769   ⟹   NP_068537
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,441,924 - 20,476,341 (+)NCBI
Rnor_6.01422,107,418 - 22,126,011 (+)NCBI
Rnor_5.01422,022,304 - 22,040,897 (+)NCBI
RGSC_v3.41421,983,705 - 22,002,744 (+)RGD
Celera1419,860,399 - 19,879,003 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092368   ⟹   XP_038948296
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,441,135 - 20,476,341 (+)NCBI
RefSeq Acc Id: XM_039092369   ⟹   XP_038948297
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,442,142 - 20,472,920 (+)NCBI
Protein Sequences
Protein RefSeqs NP_068537 (Get FASTA)   NCBI Sequence Viewer  
  XP_038948296 (Get FASTA)   NCBI Sequence Viewer  
  XP_038948297 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC99890 (Get FASTA)   NCBI Sequence Viewer  
  G3V9R3 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_068537   ⟸   NM_021769
- UniProtKB: Q9Z1G0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072150   ⟸   ENSRNOT00000080114
RefSeq Acc Id: ENSRNOP00000066303   ⟸   ENSRNOT00000072483
RefSeq Acc Id: ENSRNOP00000056924   ⟸   ENSRNOT00000060179
RefSeq Acc Id: XP_038948296   ⟸   XM_039092368
- Peptide Label: isoform X1
- UniProtKB: Q9Z1G0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038948297   ⟸   XM_039092369
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V9R3-F1-model_v2 AlphaFold G3V9R3 1-295 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620491 AgrOrtholog
BioCyc Gene G2FUF-16120 BioCyc
Ensembl Genes ENSRNOG00000001960 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000066303 ENTREZGENE
  ENSRNOP00000066303.2 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000072483 ENTREZGENE
  ENSRNOT00000072483.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Sulfotransferase_dom UniProtKB/Swiss-Prot
KEGG Report rno:60393 UniProtKB/Swiss-Prot
NCBI Gene 60393 ENTREZGENE
PANTHER SULFOTRANSFERASE 1 FAMILY MEMBER D1 UniProtKB/Swiss-Prot
  SULFOTRANSFERASE SULT UniProtKB/Swiss-Prot
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot
PhenoGen Sult1d1 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt G3V9R3 ENTREZGENE
  Q9Z1G0 ENTREZGENE
  ST1D1_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9Z1G0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Sult1d1  sulfotransferase family 1D, member 1  Sultn  N-sulfotransferase  Symbol and Name updated 1299863 APPROVED
2004-02-11 Sultn  N-sulfotransferase  Sult-n  tyrosine-ester sulfotransferase  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 Sult-n  tyrosine-ester sulfotransferase      Symbol and Name status set to provisional 70820 PROVISIONAL