Gene: Slc4a4 (solute carrier family 4 member 4) Rattus norvegicus
Symbol: Slc4a4
Name: solute carrier family 4 member 4
Description: ENCODES a protein that exhibits identical protein binding (ortholog); sodium:bicarbonate symporter activity (ortholog); INVOLVED IN bicarbonate transport (ortholog); sodium ion transport (ortholog); PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH hypertension; nephrogenic diabetes insipidus; Animal Disease Models (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: electrogenic sodium bicarbonate cotransporter 1; HHNMC; HNBC1; KNBC; na(+)/HCO3(-) cotransporter; Na+HCO3- cotransporter 4; NBC-like protein; NBC1; NBC2; Nbc4; PNBC; SLC4A5; sodium bicarbonate cotransporter; solute carrier family 4 (anion exchanger), member 4; solute carrier family 4 sodium bicarbonate cotransporter member 4; solute carrier family 4, member 4; solute carrier family 4, sodium bicarbonate cotransporter, member 4
Homo sapiens (human) : SLC4A4 (solute carrier family 4 member 4)  HGNC  Alliance
Mus musculus (house mouse) : Slc4a4 (solute carrier family 4 (anion exchanger), member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a4 (solute carrier family 4 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A4 (solute carrier family 4 member 4)
Canis lupus familiaris (dog) : SLC4A4 (solute carrier family 4 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a4 (solute carrier family 4 member 4)
Sus scrofa (pig) : SLC4A4 (solute carrier family 4 member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01420,476,258 - 20,817,042 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01420,382,241 - 20,803,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41420,381,545 - 20,739,216 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11420,381,544 - 20,739,216 (-)NCBI
Celera1418,198,665 - 18,528,992 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc4a4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68936
Created: 2001-11-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE