Anxa3 (annexin A3) - Rat Genome Database
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Gene: Anxa3 (annexin A3) Rattus norvegicus
Analyze
Symbol: Anxa3
Name: annexin A3
RGD ID: 2119
Description: Exhibits calcium-dependent phospholipid binding activity and phospholipase A2 inhibitor activity. Involved in several processes, including animal organ regeneration; hippocampus development; and response to glucocorticoid. Localizes to axon; dendrite; and neuronal cell body. Biomarker of glaucoma. Orthologous to human ANXA3 (annexin A3); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 35-alpha calcimedin; Annexin III (Lipocortin III); annexin-3; Anx3; LC3; lipocortin III; LRRGT00047; PAP-III; placental anticoagulant protein III
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21412,727,708 - 12,781,717 (-)NCBI
Rnor_6.0 Ensembl1414,364,008 - 14,426,437 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01414,371,921 - 14,426,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01414,313,646 - 14,368,216 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41414,245,112 - 14,297,100 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11414,245,111 - 14,297,100 (-)NCBI
Celera1412,785,419 - 12,839,165 (-)NCBICelera
RH 3.4 Map14155.77RGD
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-acetamidofluorene  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aniline  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
Brodifacoum  (EXP)
buspirone  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
chloropicrin  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
diethyl maleate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
fenamidone  (ISO)
fenofibrate  (EXP)
ferric ammonium citrate  (ISO)
ferric oxide  (ISO)
flurbiprofen  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
graphite  (EXP)
griseofulvin  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP)
hydroquinone  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
lithocholic acid  (ISO)
lucanthone  (ISO)
manganese(II) chloride  (EXP)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methylmercury chloride  (ISO)
mifepristone  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
Nonylphenol  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP,ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rofecoxib  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP,ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

Additional References at PubMed
PMID:2138016   PMID:2138632   PMID:7526843   PMID:9497492   PMID:9550422   PMID:15226301   PMID:15489334   PMID:16236264   PMID:16506224   PMID:17205602   PMID:17330750   PMID:17617739  
PMID:18273499   PMID:19056867   PMID:21243749   PMID:22328594   PMID:23376485   PMID:23533145   PMID:25200811   PMID:30456911   PMID:33167086  


Genomics

Comparative Map Data
Anxa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21412,727,708 - 12,781,717 (-)NCBI
Rnor_6.0 Ensembl1414,364,008 - 14,426,437 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01414,371,921 - 14,426,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01414,313,646 - 14,368,216 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41414,245,112 - 14,297,100 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11414,245,111 - 14,297,100 (-)NCBI
Celera1412,785,419 - 12,839,165 (-)NCBICelera
RH 3.4 Map14155.77RGD
Cytogenetic Map14p22NCBI
ANXA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl478,551,747 - 78,610,451 (+)EnsemblGRCh38hg38GRCh38
GRCh38478,551,761 - 78,610,447 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37479,472,924 - 79,531,601 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36479,691,766 - 79,750,629 (+)NCBINCBI36hg18NCBI36
Build 34479,832,767 - 79,888,761NCBI
Celera476,768,779 - 76,827,650 (+)NCBI
Cytogenetic Map4q21.21NCBI
HuRef475,219,132 - 75,277,891 (+)NCBIHuRef
CHM1_1479,449,236 - 79,508,101 (+)NCBICHM1_1
Anxa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39596,941,244 - 96,993,827 (+)NCBIGRCm39mm39
GRCm39 Ensembl596,941,198 - 96,993,825 (+)Ensembl
GRCm38596,793,385 - 96,845,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl596,793,339 - 96,845,966 (+)EnsemblGRCm38mm10GRCm38
MGSCv37597,222,404 - 97,274,987 (+)NCBIGRCm37mm9NCBIm37
MGSCv36597,033,717 - 97,086,270 (+)NCBImm8
Celera594,124,314 - 94,176,695 (+)NCBICelera
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
Anxa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554332,977,513 - 3,044,446 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554332,981,113 - 3,043,894 (+)NCBIChiLan1.0ChiLan1.0
ANXA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1451,432,846 - 51,491,677 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl451,432,846 - 51,491,677 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0445,585,873 - 45,644,783 (-)NCBIMhudiblu_PPA_v0panPan3
ANXA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl323,005,788 - 3,049,049 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1323,006,000 - 3,049,321 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Anxa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366762,153,752 - 2,216,498 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANXA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1873,970,314 - 73,993,039 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2878,208,453 - 78,238,185 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANXA3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1726,999,136 - 27,060,783 (+)NCBI
ChlSab1.1 Ensembl726,999,012 - 27,061,692 (+)Ensembl
Anxa3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475712,442,577 - 12,505,367 (-)NCBI

Position Markers
BF399376  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01414,372,023 - 14,372,188NCBIRnor6.0
Rnor_5.01414,313,748 - 14,313,913UniSTSRnor5.0
RGSC_v3.41414,243,328 - 14,243,493UniSTSRGSC3.4
Celera1412,785,521 - 12,785,686UniSTS
Cytogenetic Map14p22UniSTS
AA998890  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01414,373,864 - 14,374,068NCBIRnor6.0
Rnor_5.01414,315,589 - 14,315,793UniSTSRnor5.0
RGSC_v3.41414,245,169 - 14,245,373UniSTSRGSC3.4
Celera1412,787,362 - 12,787,566UniSTS
RH 3.4 Map14157.27UniSTS
Cytogenetic Map14p22UniSTS
RH129015  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01414,373,101 - 14,373,303NCBIRnor6.0
Rnor_5.01414,314,826 - 14,315,028UniSTSRnor5.0
RGSC_v3.41414,244,406 - 14,244,608UniSTSRGSC3.4
Celera1412,786,599 - 12,786,801UniSTS
RH 3.4 Map14156.57UniSTS
Cytogenetic Map14p22UniSTS
RH94682  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01414,373,873 - 14,374,068NCBIRnor6.0
Rnor_5.01414,315,598 - 14,315,793UniSTSRnor5.0
RGSC_v3.41414,245,178 - 14,245,373UniSTSRGSC3.4
Celera1412,787,371 - 12,787,566UniSTS
RH 3.4 Map14155.77UniSTS
Cytogenetic Map14p22UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14222782519230541Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14483323319909932Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14483323319909932Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14483323323004027Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14483323326466248Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14483323333040042Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141268042430155192Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141268061332593926Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:184
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000046639, ENSRNOT00000068134
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 39 46 38 19 38 21 12 24 11
Low 3 4 11 3 3 8 11 53 23 17 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000046639   ⟹   ENSRNOP00000044431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1414,364,008 - 14,390,699 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000068134   ⟹   ENSRNOP00000063496
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1414,371,928 - 14,426,437 (-)Ensembl
RefSeq Acc Id: NM_012823   ⟹   NP_036955
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,727,708 - 12,781,634 (-)NCBI
Rnor_6.01414,371,921 - 14,426,437 (-)NCBI
Rnor_5.01414,313,646 - 14,368,216 (-)NCBI
RGSC_v3.41414,245,112 - 14,297,100 (-)RGD
Celera1412,785,419 - 12,839,165 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250694   ⟹   XP_006250756
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01414,373,064 - 14,423,711 (-)NCBI
Rnor_5.01414,313,646 - 14,368,216 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250696   ⟹   XP_006250758
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,781,701 (-)NCBI
Rnor_6.01414,373,064 - 14,426,503 (-)NCBI
Rnor_5.01414,313,646 - 14,368,216 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091628   ⟹   XP_038947556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,781,717 (-)NCBI
RefSeq Acc Id: XM_039091629   ⟹   XP_038947557
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,778,458 (-)NCBI
RefSeq Acc Id: XM_039091630   ⟹   XP_038947558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,781,709 (-)NCBI
RefSeq Acc Id: XM_039091631   ⟹   XP_038947559
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,781,705 (-)NCBI
RefSeq Acc Id: XM_039091632   ⟹   XP_038947560
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,728,851 - 12,781,701 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_036955   ⟸   NM_012823
- UniProtKB: P14669 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250758   ⟸   XM_006250696
- Peptide Label: isoform X2
- UniProtKB: P14669 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250756   ⟸   XM_006250694
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000063496   ⟸   ENSRNOT00000068134
RefSeq Acc Id: ENSRNOP00000044431   ⟸   ENSRNOT00000046639
RefSeq Acc Id: XP_038947556   ⟸   XM_039091628
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947558   ⟸   XM_039091630
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947559   ⟸   XM_039091631
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947560   ⟸   XM_039091632
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038947557   ⟸   XM_039091629
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699202
Promoter ID:EPDNEW_R9727
Type:initiation region
Name:Anxa3_1
Description:annexin A3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01414,426,407 - 14,426,467EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2119 AgrOrtholog
Ensembl Genes ENSRNOG00000002045 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000044431 UniProtKB/TrEMBL
  ENSRNOP00000063496 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000046639 UniProtKB/TrEMBL
  ENSRNOT00000068134 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.220.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7191216 IMAGE-MGC_LOAD
InterPro Annexin UniProtKB/Swiss-Prot
  Annexin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Annexin_repeat_CS UniProtKB/Swiss-Prot
  Annexin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANX3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25291 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93656 IMAGE-MGC_LOAD
NCBI Gene 25291 ENTREZGENE
PANTHER PTHR10502:SF25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Annexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Anxa3 PhenoGen
PRINTS ANNEXIN UniProtKB/Swiss-Prot
  ANNEXINIII UniProtKB/Swiss-Prot
PROSITE ANNEXIN UniProtKB/Swiss-Prot
  ANNEXIN_2 UniProtKB/Swiss-Prot
SMART ANX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47874 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC205212
UniProt ANXA3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6TXF2_RAT UniProtKB/TrEMBL
UniProt Secondary Q642C2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Anxa3  annexin A3  Anx3  Annexin III (Lipocortin III)  Symbol and Name updated 1299863 APPROVED
2002-06-10 Anx3  Annexin III (Lipocortin III)      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process inhibits phospholipase A2 activity 634646
gene_protein 35 kDa membrane binding protein that is calcium and phospholipid dependent 634646