Klhl8 (kelch-like family member 8)

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Gene: Klhl8 (kelch-like family member 8) Rattus norvegicus

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Symbol:

Klhl8

Name:

kelch-like family member 8

RGD ID:

1304685

Description:

Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Orthologous to human KLHL8 (kelch like family member 8); INTERACTS WITH 2,6-dinitrotoluene; acetamide; amphetamine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

kelch-like 8; kelch-like 8 (Drosophila); kelch-like protein 8; LOC289457

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KLHL8 (kelch like family member 8)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Klhl8 (kelch-like 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Klhl8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KLHL8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KLHL8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Klhl8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KLHL8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KLHL8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Klhl8 (kelch like family member 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TATDN3 (TatD DNase domain containing 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	KLHL8 (kelch like family member 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Klhl8 (kelch-like 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	klhl8 (kelch-like family member 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	kel-8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	klhl8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	6,112,472 - 6,158,001 (+)	NCBI		GRCr8
mRatBN7.2	14	5,807,795 - 5,853,325 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	5,807,907 - 5,853,294 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	5,775,288 - 5,820,881 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	7,075,516 - 7,121,112 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	5,773,843 - 5,819,143 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	7,169,517 - 7,215,025 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	7,169,519 - 7,215,025 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	7,159,371 - 7,204,942 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	6,958,124 - 7,003,630 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	6,978,904 - 7,003,611 (+)	NCBI
Celera	14	5,946,794 - 5,992,070 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant polycystic kidney disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

amphetamine (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

chlorpyrifos (EXP)

Dibutyl phosphate (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ketamine (EXP)

nickel atom (ISO)

paracetamol (EXP)

pirinixic acid (ISO)

resveratrol (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (ISO)

ubiquitin-dependent protein catabolic process (ISO)

Cellular Component

Cul3-RING ubiquitin ligase complex (ISO)

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19158078

Genomics

Comparative Map Data

Klhl8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	6,112,472 - 6,158,001 (+)	NCBI		GRCr8
mRatBN7.2	14	5,807,795 - 5,853,325 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	5,807,907 - 5,853,294 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	5,775,288 - 5,820,881 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	7,075,516 - 7,121,112 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	5,773,843 - 5,819,143 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	7,169,517 - 7,215,025 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	7,169,519 - 7,215,025 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	7,159,371 - 7,204,942 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	6,958,124 - 7,003,630 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	6,978,904 - 7,003,611 (+)	NCBI
Celera	14	5,946,794 - 5,992,070 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

KLHL8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	87,160,103 - 87,240,531 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	87,160,103 - 87,240,314 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	88,081,255 - 88,141,770 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	88,301,238 - 88,360,698 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	88,439,392 - 88,498,853	NCBI
Celera	4	85,371,231 - 85,430,685 (-)	NCBI		Celera
Cytogenetic Map	4	q22.1	NCBI
HuRef	4	83,826,503 - 83,885,876 (-)	NCBI		HuRef
CHM1_1	4	88,059,619 - 88,119,078 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	90,489,165 - 90,569,763 (-)	NCBI		T2T-CHM13v2.0

Klhl8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	104,009,916 - 104,059,137 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	104,009,839 - 104,059,125 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	103,862,050 - 103,911,259 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	103,861,973 - 103,911,259 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	104,291,069 - 104,340,248 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	104,102,352 - 104,151,531 (-)	NCBI		MGSCv36	mm8
Celera	5	101,168,123 - 101,217,145 (-)	NCBI		Celera
Cytogenetic Map	5	E5	NCBI
cM Map	5	50.45	NCBI

Klhl8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955474	2,652,992 - 2,710,616 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955474	2,652,992 - 2,710,616 (+)	NCBI	ChiLan1.0	ChiLan1.0

KLHL8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	85,176,525 - 85,236,648 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	85,438,568 - 85,498,966 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	79,462,540 - 79,522,547 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	90,190,302 - 90,247,744 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	90,190,302 - 90,225,284 (-)	Ensembl	panpan1.1		panPan2

KLHL8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	10,656,419 - 10,687,029 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	10,659,240 - 10,686,998 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	31,224,842 - 31,297,941 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	10,710,493 - 10,781,463 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	10,708,476 - 10,739,122 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	10,790,068 - 10,862,824 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	10,617,500 - 10,690,567 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	29,264,169 - 29,337,281 (+)	NCBI		UU_Cfam_GSD_1.0

Klhl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	556,977 - 576,651 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936920	4,186 - 25,059 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936920	4,418 - 22,583 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLHL8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	131,634,209 - 131,700,068 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	131,634,171 - 131,701,161 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	140,909,603 - 140,931,918 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLHL8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	35,535,406 - 35,614,934 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	35,535,230 - 35,595,201 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	14,226,547 - 14,306,636 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klhl8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624872	3,677,397 - 3,750,867 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624872	3,675,248 - 3,750,852 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Klhl8
324 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	422
Count of miRNA genes:	235
Interacting mature miRNAs:	282
Transcripts:	ENSRNOT00000003026
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3813074	21217635	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3813074	24531477	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3813074	18274691	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
724541	Niddm53	Non-insulin dependent diabetes mellitus QTL 53		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	3813074	9088978	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3813074	30767156	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
71115	Niddm15	Non-insulin dependent diabetes mellitus QTL 15	4.8		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	14	1217606	11030812	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1217606	16960180	Rat

Markers in Region

BE102825

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	5,809,579 - 5,809,744 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	7,171,285 - 7,171,449	NCBI	Rnor6.0
Rnor_5.0	14	7,161,137 - 7,161,301	UniSTS	Rnor5.0
RGSC_v3.4	14	6,959,890 - 6,960,054	UniSTS	RGSC3.4
Celera	14	5,948,560 - 5,948,724	UniSTS
RH 3.4 Map	14	115.6	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH137860

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	5,852,281 - 5,852,525 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	7,213,982 - 7,214,225	NCBI	Rnor6.0
Rnor_5.0	14	7,203,899 - 7,204,142	UniSTS	Rnor5.0
RGSC_v3.4	14	7,002,587 - 7,002,830	UniSTS	RGSC3.4
Celera	14	5,991,027 - 5,991,270	UniSTS
RH 3.4 Map	14	115.7	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH139108

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	5,853,027 - 5,853,155 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	7,214,728 - 7,214,855	NCBI	Rnor6.0
Rnor_5.0	14	7,204,645 - 7,204,772	UniSTS	Rnor5.0
RGSC_v3.4	14	7,003,333 - 7,003,460	UniSTS	RGSC3.4
Celera	14	5,991,773 - 5,991,900	UniSTS
RH 3.4 Map	14	116.4	UniSTS
Cytogenetic Map	14	p22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001105995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000003026 ⟹ ENSRNOP00000003026

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	5,809,936 - 5,853,294 (+)	Ensembl
Rnor_6.0 Ensembl	14	7,169,519 - 7,215,025 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081600 ⟹ ENSRNOP00000070593

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	5,807,907 - 5,853,294 (+)	Ensembl
Rnor_6.0 Ensembl	14	7,171,613 - 7,214,220 (+)	Ensembl

RefSeq Acc Id:

NM_001105995 ⟹ NP_001099465

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,489 - 6,158,001 (+)	NCBI
mRatBN7.2	14	5,807,813 - 5,853,325 (+)	NCBI
Rnor_6.0	14	7,169,519 - 7,215,025 (+)	NCBI
Rnor_5.0	14	7,159,371 - 7,204,942 (+)	NCBI
RGSC_v3.4	14	6,958,124 - 7,003,630 (+)	RGD
Celera	14	5,946,794 - 5,992,070 (+)	RGD

Sequence:

show sequence

GCGCTCCGCGGAGCCGGGCACGAGCAAGCGGGCGGGCAAGTGAGCGCGTCCGCCGAGTGTCGGA
GCTGGGCTGGCGCGGCGCCGGCACGGAGCGGGTGTGGCGGCTCGGCCTGCGCGGCGGCCGCGGA
CAGAGCAAACTGTCTAATGAAATTGAAGGTTTCGAAAGATGTCTAAAGCTTAGTGGCCACATCT
ATCGTCTGTCTTCTGACCCTTAAAAAAAAAAAAACAAAGAATAAATGGGATGTTTCAGAAGAGA
GCTATTTAAAAGGAAGAGTGTTGCAAATGGCTTCAGAATCTACCAATGGGAAGCTAGCTAGGAG
TCACGTGACAAAGGGGCGGCGTCAGCAGCAGCAGCAGCAGCAGGTGAGGAGCCGGTCCTCTGTC
AGCGAGTGCGATGGCGACGACTCCTTCATCTTCGAAGCCAACGAGGCCTGGAAGGACTTTCACG
GCTCTCTCCTGGGCTTCTATGAGAACGGGGAGCTCTGTGACGTCACTCTAAAGGTCGGCTCGAA
GCTCATCTCCTGCCACAAGCTGGCGCTGGCTTGTGTCATCCCCTACTTCAGAGCCATGTTTCTT
TCTGAAATGTCTGAGGCTAAGCAGGCGCTGATCGAGATTCGGGACTTTGACGGCGATGCCGTGG
AGGACTTGGTGAAGTTCGTCTACTCTTCGCGGCTCACTCTGACAGTGGACAACGTCCAGCCTCT
GCTGTATGCAGCGTGCATCCTGCAGGTTGAACTGGTGGCCAGAGCTTGCTGCGAATACATGAAG
CTACACTTTCATCCCTCCAACTGCCTGGCTGTGCGAGCCTTTGCGGAGAGTCACAACCGAACAG
ACCTAATGGACATGGCGGACCAGTATGCGTGCGAGCACTTTACTGAAGTGGTAGAGTGTGAGGA
CTTCGTGAGCGTGTCCCCACAGCACCTGCACAAGCTCCTCTCCTCCAGCGACCTCAACATCGAC
AGCGAGAAGCAGGTCTACAGTGCCGCCATCAAGTGGCTTCTTGCCAACCCACAGCATCACCCTA
AATGGCTGGACGAGACCCTTGCCCAGGTCCGTCTGCCACTCTTGCCAGTGGATTTCCTCATGGG
CGTTGTGGCAAAAGAGCAGATTGTCAAGCAAAATCTGAAATGTAGAGACCTACTGGATGAAGCC
AGAAATTACCACCTTCATTTGAGCAGTAAACCAGTTCCTGACTTTGAGTATTCAGTCCGAACTA
CCCCGAGGAAGCATACTGCTGGTGTGCTGTTCTGTGTGGGTGGTCGAGGTGGATCTGGTGACCC
CTTTCGTAGTATCGAATGCTATTCTATCAACACAAACAGCTGGTTCTTTGGACCAGAAATGAAC
AGCCGCAGGAGGCATGTGGGCGTGATCTCTGTGGAAGGGAAAGTGTATGCCGTGGGCGGCCATG
ATGGGAACGAGCACCTAGGCAGCATGGAGATGTTTGACCCTCTCACTAACAAATGGATGGTGAA
GGCATCGATGAACACCAAGAGGCGAGGAATTGCCTTGGCCTCCTTAGGGGGCCCAATATATGCG
ATTGGAGGATTAGATGACAACACTTGCTTCAGTGACGTGGAGAGATACGACATTGAATCTGACC
AGTGGAGTACGGTGGCGCCAATGAACACTCCCCGTGGAGGTGTCGGCTCTGTGGCTTTAATCAA
CCATGTTTACGCAGTGGGTGGCAACGATGGCGTAGCCTCCTTGTCCAGTGTGGAAAGGTATCAC
CCGCATCTGGATAAGTGGGTGGAGGTGAAGGAGATGGGCCAGCGGAGAGCCGGCAATGGTGTTA
GTGAGCTTCACGGCTGCTTATACGTTGTTGGTGGTTTTGATGATAATTCCCCTCTGAGTTCGGT
TGAGCGGTACGATCCTCGGAGCAACAAGTGGGACTATGTGGCAGCGCTCACCACTCCCAGGGGT
GGCGTAGGGATTGCGACGGTGATGGGCAAGATCTTTGCAGTCGGAGGCCACAACGGCAATGCCT
ACCTCAACACAGTGGAGGCGTTCGACCCTGTGCTGAATAAATGGGAACTGGTCGGACCTGTGTC
TCACTGCCGAGCTGGTGCCGGTGTGGCCGTGTGTGACTGCTTAACTAGCCAGATCCGAGACGTA
GGTCATGGGTCCACTAACGTGGTTGACTGTATGTGATTAAGTCCCAGCAACAAGGATACAGTGC
CATCTGATGGACGGGAAGACGAGCCTTTCAACATGGCGCATTTGATTGTGACCACAGCTACTGT
CTTTGAGTGTCAGCTGTTGTAAGTAGGTCTGTGGGCTGACGGTGAGAGCTGCTAGTCACAGAGT
GAAGTGAGCTGTTTCCTGCCTCAGCAGACAGTGAGTAGGCTGGAAGCAGCCTGTCAGCCCATTC
TTGCGCTGAGAGACGTTTCATGTAGTGCCAAACCTTAAAATAGCTGTTTATTTTGATGAATAAA
ATGTAATTTATTGAGTTTTATCTGTTCTTTTTCCTGAAGAAACTAACTTCAGGCAGTAGATTTT
TTTCCCAGAGGAGAGAGAAGTCCACTCATCAACATGAGAACTTGAGGCCTGCTCCCTTGAGGAT
CACTCTACATGGTGCTGGTGAATGTATGTCTTGCTTTTTGTCTCCAGATGGTGACTTTCAGTTC
TTGGGTGTTTATGAAGTAGGGAAAATGTTTGTGTGTTTCTGAGACATTCTTGAAACCACATTAG
TGTCTGTAAGAAGGCCTTGGCCTCCATGTGGAGTTTTAGAACCACAGGACATAGCTGTGCCTGC
TTCCTCACCAAGTGTACTGGCCGCCATTCTTTTCCCATTCGTGAGAGTTTCTTGGTGATGACCG
TGGCTTGGCATGAGTGCAGCGTCCAGTGAAAAGACTGAGAAGGATGTATGAAGCCCATGCCCAC
CTAGGGAGGTTGTGGAGGCTCCTTTAACCTTGTTCTTCTGCTTAGTCGTTGAATTTGGAACCAG
GACCCATTTTCTCTTACTCTGTCATTTGTCGCCGTCTTGGGTTTCCTAATTGTACAAAGCTGAA
TTTATTTATTATCAGGACATGAATGCGTTTTTACAACATTCCTTTCTGCAGTATAGTCTGATGA
TTAGTTCCAGTTTGTCATTAATCAATAAAATATGTTGCTGGTAAAAACAGAAAAAAAATGTAAA
CTGCTAGTTTTTT

hide sequence

RefSeq Acc Id:

XM_008770004 ⟹ XP_008768226

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,494 - 6,157,982 (+)	NCBI
mRatBN7.2	14	5,807,817 - 5,853,306 (+)	NCBI
Rnor_6.0	14	7,169,517 - 7,215,001 (+)	NCBI

Sequence:

show sequence

GCGCGCTCCGCGGAGCCGGGCACGAGCAAGCGGGCGGGCAAGTGAGCGCGTCCGCCGAGTGTCG
GAGCTGGGCTGGCGCGGCGCCGGCACGGAGCGGGTGTGGCGGCTCGGCCTGCGCGGCGGCCGCG
GACAGAGGTAACCGCTGCGTCGTCCGGCGCACGGGACTCAGCCTGGAGCGGCCACCCGCGTTCG
CGTCGGTGAGGAGCGGCCGGGCGGCGCCAGCGCCATCCCTCGGGGAACCGAAGGGATCCGGGCG
GGCCTCGCGGGCCGCGCTGCCGCGAGCGGCGACGCAGTGCTGGAGATCAAATTCAGTTGACTAT
TTAAAATACACCAATTACTGTTTACTGCTTCTGCGGCCAACATCTCGTGTGTGGTCGGTCAGCC
TGTTTGCTCTGCTCTGAGGAGAAGCTGCTTAACTTCAGACAACCTCTGTGGTCGGTTCCTGGGA
TCCTTTTCTGACTTTCCACAAACTGTCTAATGAAATTGAAGGTTTCGAAAGATGTCTAAAGCTT
AGTGGCCACATCTATCGTCTGTCTTCTGACCCTTAAAAAAAAAAAAACAAAGAATAAATGGGAT
GTTTCAGAAGAGAGCTATTTAAAAGGAAGAGTGTTGCAAATGGCTTCAGAATCTACCAATGGGA
AGCTAGCTAGGAGTCACGTGACAAAGGGGCGGCGTCAGCAGCAGCAGCAGCAGCAGGTGAGGAG
CCGGTCCTCTGTCAGCGAGTGCGATGGCGACGACTCCTTCATCTTCGAAGCCAACGAGGCCTGG
AAGGACTTTCACGGCTCTCTCCTGGGCTTCTATGAGAACGGGGAGCTCTGTGACGTCACTCTAA
AGGTCGGCTCGAAGCTCATCTCCTGCCACAAGCTGGCGCTGGCTTGTGTCATCCCCTACTTCAG
AGCCATGTTTCTTTCTGAAATGTCTGAGGCTAAGCAGGCGCTGATCGAGATTCGGGACTTTGAC
GGCGATGCCGTGGAGGACTTGGTGAAGTTCGTCTACTCTTCGCGGCTCACTCTGACAGTGGACA
ACGTCCAGCCTCTGCTGTATGCAGCGTGCATCCTGCAGGTTGAACTGGTGGCCAGAGCTTGCTG
CGAATACATGAAGCTACACTTTCATCCCTCCAACTGCCTGGCTGTGCGAGCCTTTGCGGAGAGT
CACAACCGAACAGACCTAATGGACATGGCGGACCAGTATGCGTGCGAGCACTTTACTGAAGTGG
TAGAGTGTGAGGACTTCGTGAGCGTGTCCCCACAGCACCTGCACAAGCTCCTCTCCTCCAGCGA
CCTCAACATCGACAGCGAGAAGCAGGTCTACAGTGCCGCCATCAAGTGGCTTCTTGCCAACCCA
CAGCATCACCCTAAATGGCTGGACGAGACCCTTGCCCAGGTCCGTCTGCCACTCTTGCCAGTGG
ATTTCCTCATGGGCGTTGTGGCAAAAGAGCAGATTGTCAAGCAAAATCTGAAATGTAGAGACCT
ACTGGATGAAGCCAGAAATTACCACCTTCATTTGAGCAGTAAACCAGTTCCTGACTTTGAGTAT
TCAGTCCGAACTACCCCGAGGAAGCATACTGCTGGTGTGCTGTTCTGTGTGGGTGGTCGAGGTG
GATCTGGTGACCCCTTTCGTAGTATCGAATGCTATTCTATCAACACAAACAGCTGGTTCTTTGG
ACCAGAAATGAACAGCCGCAGGAGGCATGTGGGCGTGATCTCTGTGGAAGGGAAAGTGTATGCC
GTGGGCGGCCATGATGGGAACGAGCACCTAGGCAGCATGGAGATGTTTGACCCTCTCACTAACA
AATGGATGGTGAAGGCATCGATGAACACCAAGAGGCGAGGAATTGCCTTGGCCTCCTTAGGGGG
CCCAATATATGCGATTGGAGGATTAGATGACAACACTTGCTTCAGTGACGTGGAGAGATACGAC
ATTGAATCTGACCAGTGGAGTACGGTGGCGCCAATGAACACTCCCCGTGGAGGTGTCGGCTCTG
TGGCTTTAATCAACCATGTTTACGCAGTGGGTGGCAACGATGGCGTAGCCTCCTTGTCCAGTGT
GGAAAGGTATCACCCGCATCTGGATAAGTGGGTGGAGGTGAAGGAGATGGGCCAGCGGAGAGCC
GGCAATGGTGTTAGTGAGCTTCACGGCTGCTTATACGTTGTTGGTGGTTTTGATGATAATTCCC
CTCTGAGTTCGGTTGAGCGGTACGATCCTCGGAGCAACAAGTGGGACTATGTGGCAGCGCTCAC
CACTCCCAGGGGTGGCGTAGGGATTGCGACGGTGATGGGCAAGATCTTTGCAGTCGGAGGCCAC
AACGGCAATGCCTACCTCAACACAGTGGAGGCGTTCGACCCTGTGCTGAATAAATGGGAACTGG
TCGGACCTGTGTCTCACTGCCGAGCTGGTGCCGGTGTGGCCGTGTGTGACTGCTTAACTAGCCA
GATCCGAGACGTAGGTCATGGGTCCACTAACGTGGTTGACTGTATGTGATTAAGTCCCAGCAAC
AAGGATACAGTGCCATCTGATGGACGGGAAGACGAGCCTTTCAACATGGCGCATTTGATTGTGA
CCACAGCTACTGTCTTTGAGTGTCAGCTGTTGTAAGTAGGTCTGTGGGCTGACGGTGAGAGCTG
CTAGTCACAGAGTGAAGTGAGCTGTTTCCTGCCTCAGCAGACAGTGAGTAGGCTGGAAGCAGCC
TGTCAGCCCATTCTTGCGCTGAGAGACGTTTCATGTAGTGCCAAACCTTAAAATAGCTGTTTAT
TTTGATGAATAAAATGTAATTTATTGAGTTTTATCTGTTCTTTTTCCTGAAGAAACTAACTTCA
GGCAGTAGATTTTTTTCCCAGAGGAGAGAGAAGTCCACTCATCAACATGAGAACTTGAGGCCTG
CTCCCTTGAGGATCACTCTACATGGTGCTGGTGAATGTATGTCTTGCTTTTTGTCTCCAGATGG
TGACTTTCAGTTCTTGGGTGTTTATGAAGTAGGGAAAATGTTTGTGTGTTTCTGAGACATTCTT
GAAACCACATTAGTGTCTGTAAGAAGGCCTTGGCCTCCATGTGGAGTTTTAGAACCACAGGACA
TAGCTGTGCCTGCTTCCTCACCAAGTGTACTGGCCGCCATTCTTTTCCCATTCGTGAGAGTTTC
TTGGTGATGACCGTGGCTTGGCATGAGTGCAGCGTCCAGTGAAAAGACTGAGAAGGATGTATGA
AGCCCATGCCCACCTAGGGAGGTTGTGGAGGCTCCTTTAACCTTGTTCTTCTGCTTAGTCGTTG
AATTTGGAACCAGGACCCATTTTCTCTTACTCTGTCATTTGTCGCCGTCTTGGGTTTCCTAATT
GTACAAAGCTGAATTTATTTATTATCAGGACATGAATGCGTTTTTACAACATTCCTTTCTGCAG
TATAGTCTGATGATTAGTTCCAGTTTGTCATTAATCAATAAAATATGTTGCTGGTAAAAACAGA
AA

hide sequence

RefSeq Acc Id:

XM_008770005 ⟹ XP_008768227

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,478 - 6,157,982 (+)	NCBI
mRatBN7.2	14	5,807,817 - 5,853,306 (+)	NCBI
Rnor_6.0	14	7,169,517 - 7,215,001 (+)	NCBI

Sequence:

show sequence

GCGCGCTCCGCGGAGCCGGGCACGAGCAAGCGGGCGGGCAAGTGAGCGCGTCCGCCGAGTGTCG
GAGCTGGGCTGGCGCGGCGCCGGCACGGAGCGGGTGTGGCGGCTCGGCCTGCGCGGCGGCCGCG
GACAGAGGTAACCGCTGCGTCGTCCGGCGCACGGGACTCAGCCTGGAGCGGCCACCCGCGTTCG
CGTCGTGCTGGAGATCAAATTCAGTTGACTATTTAAAATACACCAATTACTGTTTACTGCTTCT
GCGGCCAACATCTCGTGTGTGGTCGGTCAGCCTGTTTGCTCTGCTCTGAGGAGAAGCTGCTTAA
CTTCAGACAACCTCTGTGGTCGGTTCCTGGGATCCTTTTCTGACTTTCCACAAACTGTCTAATG
AAATTGAAGGTTTCGAAAGATGTCTAAAGCTTAGTGGCCACATCTATCGTCTGTCTTCTGACCC
TTAAAAAAAAAAAAACAAAGAATAAATGGGATGTTTCAGAAGAGAGCTATTTAAAAGGAAGAGT
GTTGCAAATGGCTTCAGAATCTACCAATGGGAAGCTAGCTAGGAGTCACGTGACAAAGGGGCGG
CGTCAGCAGCAGCAGCAGCAGCAGGTGAGGAGCCGGTCCTCTGTCAGCGAGTGCGATGGCGACG
ACTCCTTCATCTTCGAAGCCAACGAGGCCTGGAAGGACTTTCACGGCTCTCTCCTGGGCTTCTA
TGAGAACGGGGAGCTCTGTGACGTCACTCTAAAGGTCGGCTCGAAGCTCATCTCCTGCCACAAG
CTGGCGCTGGCTTGTGTCATCCCCTACTTCAGAGCCATGTTTCTTTCTGAAATGTCTGAGGCTA
AGCAGGCGCTGATCGAGATTCGGGACTTTGACGGCGATGCCGTGGAGGACTTGGTGAAGTTCGT
CTACTCTTCGCGGCTCACTCTGACAGTGGACAACGTCCAGCCTCTGCTGTATGCAGCGTGCATC
CTGCAGGTTGAACTGGTGGCCAGAGCTTGCTGCGAATACATGAAGCTACACTTTCATCCCTCCA
ACTGCCTGGCTGTGCGAGCCTTTGCGGAGAGTCACAACCGAACAGACCTAATGGACATGGCGGA
CCAGTATGCGTGCGAGCACTTTACTGAAGTGGTAGAGTGTGAGGACTTCGTGAGCGTGTCCCCA
CAGCACCTGCACAAGCTCCTCTCCTCCAGCGACCTCAACATCGACAGCGAGAAGCAGGTCTACA
GTGCCGCCATCAAGTGGCTTCTTGCCAACCCACAGCATCACCCTAAATGGCTGGACGAGACCCT
TGCCCAGGTCCGTCTGCCACTCTTGCCAGTGGATTTCCTCATGGGCGTTGTGGCAAAAGAGCAG
ATTGTCAAGCAAAATCTGAAATGTAGAGACCTACTGGATGAAGCCAGAAATTACCACCTTCATT
TGAGCAGTAAACCAGTTCCTGACTTTGAGTATTCAGTCCGAACTACCCCGAGGAAGCATACTGC
TGGTGTGCTGTTCTGTGTGGGTGGTCGAGGTGGATCTGGTGACCCCTTTCGTAGTATCGAATGC
TATTCTATCAACACAAACAGCTGGTTCTTTGGACCAGAAATGAACAGCCGCAGGAGGCATGTGG
GCGTGATCTCTGTGGAAGGGAAAGTGTATGCCGTGGGCGGCCATGATGGGAACGAGCACCTAGG
CAGCATGGAGATGTTTGACCCTCTCACTAACAAATGGATGGTGAAGGCATCGATGAACACCAAG
AGGCGAGGAATTGCCTTGGCCTCCTTAGGGGGCCCAATATATGCGATTGGAGGATTAGATGACA
ACACTTGCTTCAGTGACGTGGAGAGATACGACATTGAATCTGACCAGTGGAGTACGGTGGCGCC
AATGAACACTCCCCGTGGAGGTGTCGGCTCTGTGGCTTTAATCAACCATGTTTACGCAGTGGGT
GGCAACGATGGCGTAGCCTCCTTGTCCAGTGTGGAAAGGTATCACCCGCATCTGGATAAGTGGG
TGGAGGTGAAGGAGATGGGCCAGCGGAGAGCCGGCAATGGTGTTAGTGAGCTTCACGGCTGCTT
ATACGTTGTTGGTGGTTTTGATGATAATTCCCCTCTGAGTTCGGTTGAGCGGTACGATCCTCGG
AGCAACAAGTGGGACTATGTGGCAGCGCTCACCACTCCCAGGGGTGGCGTAGGGATTGCGACGG
TGATGGGCAAGATCTTTGCAGTCGGAGGCCACAACGGCAATGCCTACCTCAACACAGTGGAGGC
GTTCGACCCTGTGCTGAATAAATGGGAACTGGTCGGACCTGTGTCTCACTGCCGAGCTGGTGCC
GGTGTGGCCGTGTGTGACTGCTTAACTAGCCAGATCCGAGACGTAGGTCATGGGTCCACTAACG
TGGTTGACTGTATGTGATTAAGTCCCAGCAACAAGGATACAGTGCCATCTGATGGACGGGAAGA
CGAGCCTTTCAACATGGCGCATTTGATTGTGACCACAGCTACTGTCTTTGAGTGTCAGCTGTTG
TAAGTAGGTCTGTGGGCTGACGGTGAGAGCTGCTAGTCACAGAGTGAAGTGAGCTGTTTCCTGC
CTCAGCAGACAGTGAGTAGGCTGGAAGCAGCCTGTCAGCCCATTCTTGCGCTGAGAGACGTTTC
ATGTAGTGCCAAACCTTAAAATAGCTGTTTATTTTGATGAATAAAATGTAATTTATTGAGTTTT
ATCTGTTCTTTTTCCTGAAGAAACTAACTTCAGGCAGTAGATTTTTTTCCCAGAGGAGAGAGAA
GTCCACTCATCAACATGAGAACTTGAGGCCTGCTCCCTTGAGGATCACTCTACATGGTGCTGGT
GAATGTATGTCTTGCTTTTTGTCTCCAGATGGTGACTTTCAGTTCTTGGGTGTTTATGAAGTAG
GGAAAATGTTTGTGTGTTTCTGAGACATTCTTGAAACCACATTAGTGTCTGTAAGAAGGCCTTG
GCCTCCATGTGGAGTTTTAGAACCACAGGACATAGCTGTGCCTGCTTCCTCACCAAGTGTACTG
GCCGCCATTCTTTTCCCATTCGTGAGAGTTTCTTGGTGATGACCGTGGCTTGGCATGAGTGCAG
CGTCCAGTGAAAAGACTGAGAAGGATGTATGAAGCCCATGCCCACCTAGGGAGGTTGTGGAGGC
TCCTTTAACCTTGTTCTTCTGCTTAGTCGTTGAATTTGGAACCAGGACCCATTTTCTCTTACTC
TGTCATTTGTCGCCGTCTTGGGTTTCCTAATTGTACAAAGCTGAATTTATTTATTATCAGGACA
TGAATGCGTTTTTACAACATTCCTTTCTGCAGTATAGTCTGATGATTAGTTCCAGTTTGTCATT
AATCAATAAAATATGTTGCTGGTAAAAACAGAAA

hide sequence

RefSeq Acc Id:

XM_008770006 ⟹ XP_008768228

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,472 - 6,157,982 (+)	NCBI
mRatBN7.2	14	5,807,795 - 5,853,306 (+)	NCBI
Rnor_6.0	14	7,169,517 - 7,215,001 (+)	NCBI

Sequence:

show sequence

GCGCGCTCCGCGGAGCCGGGCACGAGCAAGCGGGCGGGCAAGTGAGCGCGTCCGCCGAGTGTCG
GAGCTGGGCTGGCGCGGCGCCGGCACGGAGCGGGTGTGGCGGCTCGGCCTGCGCGGCGGCCGCG
GACAGAGTGCTGGAGATCAAATTCAGTTGACTATTTAAAATACACCAATTACTGTTTACTGCTT
CTGCGGCCAACATCTCGTGTGTGGTCGGTCAGCCTGTTTGCTCTGCTCTGAGGAGAAGCTGCTT
AACTTCAGACAACCTCTGTGGTCGGTTCCTGGGATCCTTTTCTGACTTTCCACAAACTGTCTAA
TGAAATTGAAGGTTTCGAAAGATGTCTAAAGCTTAGTGGCCACATCTATCGTCTGTCTTCTGAC
CCTTAAAAAAAAAAAAACAAAGAATAAATGGGATGTTTCAGAAGAGAGCTATTTAAAAGGAAGA
GTGTTGCAAATGGCTTCAGAATCTACCAATGGGAAGCTAGCTAGGAGTCACGTGACAAAGGGGC
GGCGTCAGCAGCAGCAGCAGCAGCAGGTGAGGAGCCGGTCCTCTGTCAGCGAGTGCGATGGCGA
CGACTCCTTCATCTTCGAAGCCAACGAGGCCTGGAAGGACTTTCACGGCTCTCTCCTGGGCTTC
TATGAGAACGGGGAGCTCTGTGACGTCACTCTAAAGGTCGGCTCGAAGCTCATCTCCTGCCACA
AGCTGGCGCTGGCTTGTGTCATCCCCTACTTCAGAGCCATGTTTCTTTCTGAAATGTCTGAGGC
TAAGCAGGCGCTGATCGAGATTCGGGACTTTGACGGCGATGCCGTGGAGGACTTGGTGAAGTTC
GTCTACTCTTCGCGGCTCACTCTGACAGTGGACAACGTCCAGCCTCTGCTGTATGCAGCGTGCA
TCCTGCAGGTTGAACTGGTGGCCAGAGCTTGCTGCGAATACATGAAGCTACACTTTCATCCCTC
CAACTGCCTGGCTGTGCGAGCCTTTGCGGAGAGTCACAACCGAACAGACCTAATGGACATGGCG
GACCAGTATGCGTGCGAGCACTTTACTGAAGTGGTAGAGTGTGAGGACTTCGTGAGCGTGTCCC
CACAGCACCTGCACAAGCTCCTCTCCTCCAGCGACCTCAACATCGACAGCGAGAAGCAGGTCTA
CAGTGCCGCCATCAAGTGGCTTCTTGCCAACCCACAGCATCACCCTAAATGGCTGGACGAGACC
CTTGCCCAGGTCCGTCTGCCACTCTTGCCAGTGGATTTCCTCATGGGCGTTGTGGCAAAAGAGC
AGATTGTCAAGCAAAATCTGAAATGTAGAGACCTACTGGATGAAGCCAGAAATTACCACCTTCA
TTTGAGCAGTAAACCAGTTCCTGACTTTGAGTATTCAGTCCGAACTACCCCGAGGAAGCATACT
GCTGGTGTGCTGTTCTGTGTGGGTGGTCGAGGTGGATCTGGTGACCCCTTTCGTAGTATCGAAT
GCTATTCTATCAACACAAACAGCTGGTTCTTTGGACCAGAAATGAACAGCCGCAGGAGGCATGT
GGGCGTGATCTCTGTGGAAGGGAAAGTGTATGCCGTGGGCGGCCATGATGGGAACGAGCACCTA
GGCAGCATGGAGATGTTTGACCCTCTCACTAACAAATGGATGGTGAAGGCATCGATGAACACCA
AGAGGCGAGGAATTGCCTTGGCCTCCTTAGGGGGCCCAATATATGCGATTGGAGGATTAGATGA
CAACACTTGCTTCAGTGACGTGGAGAGATACGACATTGAATCTGACCAGTGGAGTACGGTGGCG
CCAATGAACACTCCCCGTGGAGGTGTCGGCTCTGTGGCTTTAATCAACCATGTTTACGCAGTGG
GTGGCAACGATGGCGTAGCCTCCTTGTCCAGTGTGGAAAGGTATCACCCGCATCTGGATAAGTG
GGTGGAGGTGAAGGAGATGGGCCAGCGGAGAGCCGGCAATGGTGTTAGTGAGCTTCACGGCTGC
TTATACGTTGTTGGTGGTTTTGATGATAATTCCCCTCTGAGTTCGGTTGAGCGGTACGATCCTC
GGAGCAACAAGTGGGACTATGTGGCAGCGCTCACCACTCCCAGGGGTGGCGTAGGGATTGCGAC
GGTGATGGGCAAGATCTTTGCAGTCGGAGGCCACAACGGCAATGCCTACCTCAACACAGTGGAG
GCGTTCGACCCTGTGCTGAATAAATGGGAACTGGTCGGACCTGTGTCTCACTGCCGAGCTGGTG
CCGGTGTGGCCGTGTGTGACTGCTTAACTAGCCAGATCCGAGACGTAGGTCATGGGTCCACTAA
CGTGGTTGACTGTATGTGATTAAGTCCCAGCAACAAGGATACAGTGCCATCTGATGGACGGGAA
GACGAGCCTTTCAACATGGCGCATTTGATTGTGACCACAGCTACTGTCTTTGAGTGTCAGCTGT
TGTAAGTAGGTCTGTGGGCTGACGGTGAGAGCTGCTAGTCACAGAGTGAAGTGAGCTGTTTCCT
GCCTCAGCAGACAGTGAGTAGGCTGGAAGCAGCCTGTCAGCCCATTCTTGCGCTGAGAGACGTT
TCATGTAGTGCCAAACCTTAAAATAGCTGTTTATTTTGATGAATAAAATGTAATTTATTGAGTT
TTATCTGTTCTTTTTCCTGAAGAAACTAACTTCAGGCAGTAGATTTTTTTCCCAGAGGAGAGAG
AAGTCCACTCATCAACATGAGAACTTGAGGCCTGCTCCCTTGAGGATCACTCTACATGGTGCTG
GTGAATGTATGTCTTGCTTTTTGTCTCCAGATGGTGACTTTCAGTTCTTGGGTGTTTATGAAGT
AGGGAAAATGTTTGTGTGTTTCTGAGACATTCTTGAAACCACATTAGTGTCTGTAAGAAGGCCT
TGGCCTCCATGTGGAGTTTTAGAACCACAGGACATAGCTGTGCCTGCTTCCTCACCAAGTGTAC
TGGCCGCCATTCTTTTCCCATTCGTGAGAGTTTCTTGGTGATGACCGTGGCTTGGCATGAGTGC
AGCGTCCAGTGAAAAGACTGAGAAGGATGTATGAAGCCCATGCCCACCTAGGGAGGTTGTGGAG
GCTCCTTTAACCTTGTTCTTCTGCTTAGTCGTTGAATTTGGAACCAGGACCCATTTTCTCTTAC
TCTGTCATTTGTCGCCGTCTTGGGTTTCCTAATTGTACAAAGCTGAATTTATTTATTATCAGGA
CATGAATGCGTTTTTACAACATTCCTTTCTGCAGTATAGTCTGATGATTAGTTCCAGTTTGTCA
TTAATCAATAAAATATGTTGCTGGTAAAAACAGAAA

hide sequence

RefSeq Acc Id:

XM_063272895 ⟹ XP_063128965

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,494 - 6,157,982 (+)	NCBI

RefSeq Acc Id:

XM_063272896 ⟹ XP_063128966

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	6,112,494 - 6,157,982 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099465	(Get FASTA)	NCBI Sequence Viewer
	XP_008768226	(Get FASTA)	NCBI Sequence Viewer
	XP_008768227	(Get FASTA)	NCBI Sequence Viewer
	XP_008768228	(Get FASTA)	NCBI Sequence Viewer
	XP_063128965	(Get FASTA)	NCBI Sequence Viewer
	XP_063128966	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL99514	(Get FASTA)	NCBI Sequence Viewer
	EDL99515	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003026.6
	ENSRNOP00000070593.1

RefSeq Acc Id:

NP_001099465 ⟸ NM_001105995

- UniProtKB:

A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYEN
GELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYS
SRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQY
ACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQ
VRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGV
LFCVGGRGGSGDPFRSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSM
EMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMN
TPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYV
VGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFD
PVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM

hide sequence

RefSeq Acc Id:	XP_008768226 ⟸ XM_008770004
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYEN GELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYS SRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQY ACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQ VRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGV LFCVGGRGGSGDPFRSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSM EMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMN TPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYV VGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFD PVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM hide sequence

RefSeq Acc Id:	XP_008768227 ⟸ XM_008770005
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYEN GELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYS SRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQY ACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQ VRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGV LFCVGGRGGSGDPFRSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSM EMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMN TPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYV VGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFD PVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM hide sequence

RefSeq Acc Id:	XP_008768228 ⟸ XM_008770006
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYEN GELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYS SRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQY ACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQ VRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGV LFCVGGRGGSGDPFRSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSM EMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMN TPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYV VGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFD PVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM hide sequence

Ensembl Acc Id:

ENSRNOP00000070593 ⟸ ENSRNOT00000081600

Ensembl Acc Id:

ENSRNOP00000003026 ⟸ ENSRNOT00000003026

RefSeq Acc Id:	XP_063128966 ⟸ XM_063272896
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128965 ⟸ XM_063272895
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYB7 (UniProtKB/TrEMBL), A6K5U5 (UniProtKB/TrEMBL)

Protein Domains

BTB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZHE1-F1-model_v2	AlphaFold	D3ZHE1	1-621	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304685	AgrOrtholog
BioCyc Gene	G2FUF-16494	BioCyc
Ensembl Genes	ENSRNOG00000002214	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000003026.7	UniProtKB/TrEMBL
	ENSRNOT00000081600.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.420	UniProtKB/TrEMBL
	2.120.10.80	UniProtKB/TrEMBL
InterPro	BACK	UniProtKB/TrEMBL
	BTB-kelch_protein	UniProtKB/TrEMBL
	BTB/POZ-like	UniProtKB/TrEMBL
	BTB/POZ_fold	UniProtKB/TrEMBL
	Kelch-typ_b-propeller	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
KEGG Report	rno:289457	UniProtKB/TrEMBL
NCBI Gene	289457	ENTREZGENE
PANTHER	ACTIN-BINDING PROTEIN IPP	UniProtKB/TrEMBL
	KELCH PROTEIN	UniProtKB/TrEMBL
	KELCH-LIKE PROTEIN DIABLO	UniProtKB/TrEMBL
	LD33804P	UniProtKB/TrEMBL
Pfam	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch_1	UniProtKB/TrEMBL
PhenoGen	Klhl8	PhenoGen
PIRSF	Kelch-like_protein_gigaxonin	UniProtKB/TrEMBL
PRINTS	KELCHREPEAT	UniProtKB/TrEMBL
PROSITE	BTB	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002214	RatGTEx
SMART	BACK	UniProtKB/TrEMBL
	BTB	UniProtKB/TrEMBL
	Kelch	UniProtKB/TrEMBL
Superfamily-SCOP	BTB/POZ_fold	UniProtKB/TrEMBL
	SSF117281	UniProtKB/TrEMBL
UniProt	A0A0G2JYB7	ENTREZGENE, UniProtKB/TrEMBL
	A6K5U5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZHE1_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-02-06	Klhl8	kelch-like family member 8	Klhl8	kelch-like 8 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Klhl8	kelch-like 8 (Drosophila)	Klhl8_predicted	kelch-like 8 (Drosophila) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Klhl8_predicted	kelch-like 8 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar