Hnrnpdl (heterogeneous nuclear ribonucleoprotein D-like) - Rat Genome Database
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Gene: Hnrnpdl (heterogeneous nuclear ribonucleoprotein D-like) Rattus norvegicus
Analyze
Symbol: Hnrnpdl
Name: heterogeneous nuclear ribonucleoprotein D-like
RGD ID: 1309950
Description: Predicted to have nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Predicted to localize to nucleoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3. Orthologous to human HNRNPDL (heterogeneous nuclear ribonucleoprotein D like); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hnRNP D-like; hnRNP DL; hnRNP-DL; hnRPD-like protein; Hnrpdl; LOC305178; MGC125262
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.0 Ensembl1411,198,896 - 11,202,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01411,199,114 - 11,204,670 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01411,142,952 - 11,148,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41410,861,054 - 10,864,322 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11410,860,747 - 10,865,255 (+)NCBI
Celera149,659,535 - 9,662,803 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
Aroclor 1254  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
diallyl trisulfide  (ISO)
dibutyl phthalate  (EXP,ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
lovastatin  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nitroprusside  (ISO)
ouabain  (ISO)
ozone  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
pyrogallol  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
Soman  (EXP)
succimer  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
topotecan  (ISO)
Tributyltin oxide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleoplasm  (IBA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

Additional References at PubMed
PMID:9538234   PMID:10717477   PMID:12477932   PMID:22658674   PMID:22681889   PMID:23376485   PMID:25931508   PMID:26316108   PMID:29476059  


Genomics

Comparative Map Data
Hnrnpdl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.0 Ensembl1411,198,896 - 11,202,669 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01411,199,114 - 11,204,670 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01411,142,952 - 11,148,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41410,861,054 - 10,864,322 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11410,860,747 - 10,865,255 (+)NCBI
Celera149,659,535 - 9,662,803 (+)NCBICelera
Cytogenetic Map14p22NCBI
HNRNPDL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl482,422,565 - 82,430,462 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl482,422,564 - 82,430,408 (-)EnsemblGRCh38hg38GRCh38
GRCh38482,422,564 - 82,430,462 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37483,343,717 - 83,351,615 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36483,563,371 - 83,570,402 (-)NCBINCBI36hg18NCBI36
Celera480,635,634 - 80,642,665 (-)NCBI
Cytogenetic Map4q21.22NCBI
HuRef479,085,093 - 79,092,735 (-)NCBIHuRef
CHM1_1483,320,226 - 83,327,863 (-)NCBICHM1_1
Hnrnpdl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395100,181,436 - 100,187,769 (-)NCBIGRCm39mm39
GRCm39 Ensembl5100,181,436 - 100,187,523 (-)Ensembl
GRCm385100,033,577 - 100,039,936 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5100,033,577 - 100,039,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv375100,462,596 - 100,468,241 (-)NCBIGRCm37mm9NCBIm37
MGSCv365100,275,023 - 100,279,179 (-)NCBImm8
Celera597,347,081 - 97,352,727 (-)NCBICelera
Cytogenetic Map5E4NCBI
cM Map548.46NCBI
Hnrnpdl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554336,512,399 - 6,522,377 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554336,515,509 - 6,522,081 (-)NCBIChiLan1.0ChiLan1.0
HNRNPDL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1447,621,973 - 47,628,893 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl447,621,973 - 47,628,885 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0441,771,512 - 41,777,135 (+)NCBIMhudiblu_PPA_v0panPan3
HNRNPDL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,401,266 - 6,408,006 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,402,762 - 6,407,845 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3235,473,221 - 35,479,998 (+)NCBI
ROS_Cfam_1.0326,424,627 - 6,431,432 (-)NCBI
UMICH_Zoey_3.1326,496,916 - 6,503,771 (-)NCBI
UNSW_CanFamBas_1.0326,361,500 - 6,368,282 (-)NCBI
UU_Cfam_GSD_1.03233,594,663 - 33,601,440 (+)NCBI
Hnrnpdl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2NW_0244052855,901,016 - 5,906,269 (+)NCBI
SpeTri2.0NW_0049367382,063,109 - 2,068,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPDL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8135,802,894 - 135,809,866 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18135,802,530 - 135,809,871 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28145,172,725 - 145,177,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPDL
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1730,804,807 - 30,810,539 (-)NCBI
ChlSab1.1 Ensembl730,805,749 - 30,810,720 (-)Ensembl
Hnrnpdl
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247578,488,619 - 8,495,498 (+)NCBI

Position Markers
RH143237  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.096,475,551 - 6,475,799NCBIRnor6.0
Rnor_5.095,522,043 - 5,522,291UniSTSRnor5.0
Celera94,513,889 - 4,514,137UniSTS
Cytogenetic Map14p22UniSTS
HNRPDL  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01411,200,654 - 11,202,118NCBIRnor6.0
Rnor_5.01411,144,489 - 11,145,953UniSTSRnor5.0
RGSC_v3.41410,862,304 - 10,863,768UniSTSRGSC3.4
Celera149,660,785 - 9,662,249UniSTS
Cytogenetic Map14p22UniSTS
HNRPDL  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01411,199,489 - 11,200,591NCBIRnor6.0
Rnor_5.01411,143,324 - 11,144,426UniSTSRnor5.0
RGSC_v3.41410,861,139 - 10,862,241UniSTSRGSC3.4
Celera149,659,620 - 9,660,722UniSTS
Cytogenetic Map14p22UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14483323326466248Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14222782519230541Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14222782512680613Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14483323333040042Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14483323323004027Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14483323319909932Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14483323319909932Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:34
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000003106
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003106   ⟹   ENSRNOP00000003106
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1411,199,404 - 11,202,669 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079767   ⟹   ENSRNOP00000075589
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1411,198,896 - 11,202,325 (+)Ensembl
RefSeq Acc Id: NM_001033696   ⟹   NP_001028868
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,383 - 9,561,651 (+)NCBI
Rnor_6.01411,199,404 - 11,202,672 (+)NCBI
Rnor_5.01411,142,952 - 11,148,504 (+)NCBI
RGSC_v3.41410,861,054 - 10,864,322 (+)RGD
Celera149,659,535 - 9,662,803 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250662   ⟹   XP_006250724
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.01411,199,114 - 11,204,670 (+)NCBI
Rnor_5.01411,142,952 - 11,148,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250663   ⟹   XP_006250725
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.01411,199,114 - 11,204,670 (+)NCBI
Rnor_5.01411,142,952 - 11,148,504 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770024   ⟹   XP_008768246
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.01411,199,114 - 11,204,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091837   ⟹   XP_038947765
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,374 - 9,563,654 (+)NCBI
RefSeq Acc Id: XM_039091838   ⟹   XP_038947766
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,374 - 9,563,654 (+)NCBI
RefSeq Acc Id: XR_005492930
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
RefSeq Acc Id: XR_359349
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.01411,199,114 - 11,204,670 (+)NCBI
Rnor_5.01411,142,952 - 11,148,504 (+)NCBI
Sequence:
RefSeq Acc Id: XR_359350
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2149,558,079 - 9,563,654 (+)NCBI
Rnor_6.01411,199,114 - 11,204,670 (+)NCBI
Rnor_5.01411,142,952 - 11,148,504 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001028868   ⟸   NM_001033696
- UniProtKB: Q3SWU3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250724   ⟸   XM_006250662
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250725   ⟸   XM_006250663
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768246   ⟸   XM_008770024
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075589   ⟸   ENSRNOT00000079767
RefSeq Acc Id: ENSRNOP00000003106   ⟸   ENSRNOT00000003106
RefSeq Acc Id: XP_038947765   ⟸   XM_039091837
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038947766   ⟸   XM_039091838
- Peptide Label: isoform X2
Protein Domains
RRM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699198
Promoter ID:EPDNEW_R9722
Type:single initiation site
Name:Hnrnpdl_1
Description:heterogeneous nuclear ribonucleoprotein D-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01411,199,389 - 11,199,449EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 11144925 11144926 C T snv Crl:SD (UDEL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309950 AgrOrtholog
Ensembl Genes ENSRNOG00000002270 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003106 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000075589 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003106 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079767 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7461444 IMAGE-MGC_LOAD
InterPro hnRPDL_RRM1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305178 UniProtKB/Swiss-Prot
MGC_CLONE MGC:125262 IMAGE-MGC_LOAD
NCBI Gene 305178 ENTREZGENE
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hnrnpdl PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KAZ7 ENTREZGENE, UniProtKB/TrEMBL
  HNRDL_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Hnrnpdl  heterogeneous nuclear ribonucleoprotein D-like  Hnrpdl  heterogeneous nuclear ribonucleoprotein D-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Hnrpdl  heterogeneous nuclear ribonucleoprotein D-like  Hnrpdl_predicted  heterogeneous nuclear ribonucleoprotein D-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Hnrpdl_predicted  heterogeneous nuclear ribonucleoprotein D-like (predicted)      Symbol and Name status set to approved 70820 APPROVED