Fras1 (Fraser extracellular matrix complex subunit 1) - Rat Genome Database

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Gene: Fras1 (Fraser extracellular matrix complex subunit 1) Rattus norvegicus
Analyze
Symbol: Fras1
Name: Fraser extracellular matrix complex subunit 1
RGD ID: 1306516
Description: Predicted to be involved in cell communication. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; metanephros morphogenesis; and roof of mouth development. Predicted to be located in basement membrane. Human ortholog(s) of this gene implicated in Fraser syndrome 1. Orthologous to human FRAS1 (Fraser extracellular matrix complex subunit 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: extracellular matrix protein FRAS1; extracellular matrix protein FRAS1-like; Fraser syndrome 1; Fraser syndrome 1 homolog; Fraser syndrome 1 homolog (human); LOC103693728; LOC289486
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21412,791,407 - 13,200,862 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1412,793,599 - 13,200,726 (-)Ensembl
Rnor_6.01414,438,392 - 14,853,016 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1414,439,082 - 14,689,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01414,380,117 - 14,795,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41414,309,668 - 14,574,022 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11414,340,005 - 14,589,252 (-)NCBI
Celera1412,851,004 - 13,251,138 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-lipoic acid  (ISO)
1,2-dichloroethane  (ISO)
1,4-dioxane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP)
bisphenol F  (ISO)
butanal  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydroquinone O-beta-D-glucopyranoside  (ISO)
lipoic acid  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
phenformin  (EXP)
phenylmercury acetate  (ISO)
potassium dichromate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
temozolomide  (ISO)
tetrachloroethene  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15345741   PMID:15623520   PMID:15838507   PMID:16880404   PMID:17251066   PMID:17596926   PMID:18757743   PMID:23469164   PMID:23669348  


Genomics

Comparative Map Data
Fras1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21412,791,407 - 13,200,862 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1412,793,599 - 13,200,726 (-)Ensembl
Rnor_6.01414,438,392 - 14,853,016 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1414,439,082 - 14,689,554 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01414,380,117 - 14,795,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41414,309,668 - 14,574,022 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11414,340,005 - 14,589,252 (-)NCBI
Celera1412,851,004 - 13,251,138 (-)NCBICelera
Cytogenetic Map14p22NCBI
FRAS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38478,057,323 - 78,544,269 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl478,057,323 - 78,544,269 (+)EnsemblGRCh38hg38GRCh38
GRCh37478,978,477 - 79,465,423 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36479,198,120 - 79,684,447 (+)NCBINCBI36hg18NCBI36
Build 34479,336,312 - 79,724,964NCBI
Celera476,280,569 - 76,761,461 (+)NCBI
Cytogenetic Map4q21.21NCBI
HuRef474,729,839 - 75,211,820 (+)NCBIHuRef
CHM1_1478,955,468 - 79,441,921 (+)NCBICHM1_1
T2T-CHM13v2.0481,398,139 - 81,879,833 (+)NCBI
Fras1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39596,518,622 - 96,932,592 (+)NCBIGRCm39mm39
GRCm39 Ensembl596,521,814 - 96,932,587 (+)Ensembl
GRCm38596,373,777 - 96,784,733 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl596,373,955 - 96,784,728 (+)EnsemblGRCm38mm10GRCm38
MGSCv37596,802,974 - 97,213,747 (+)NCBIGRCm37mm9NCBIm37
MGSCv36596,614,257 - 97,025,030 (+)NCBImm8
Celera593,713,114 - 94,117,836 (+)NCBICelera
Cytogenetic Map5E3NCBI
Fras1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554332,547,323 - 2,957,495 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554332,547,228 - 2,957,294 (+)NCBIChiLan1.0ChiLan1.0
FRAS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1451,497,242 - 51,983,161 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl451,500,396 - 51,981,476 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0445,650,346 - 46,138,222 (-)NCBIMhudiblu_PPA_v0panPan3
FRAS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1322,558,442 - 2,993,199 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl322,558,354 - 2,991,063 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3238,900,653 - 39,334,034 (-)NCBI
ROS_Cfam_1.0322,585,113 - 3,019,145 (+)NCBI
ROS_Cfam_1.0 Ensembl322,585,107 - 3,017,320 (+)Ensembl
UMICH_Zoey_3.1322,573,250 - 3,006,733 (+)NCBI
UNSW_CanFamBas_1.0322,521,646 - 2,954,866 (+)NCBI
UU_Cfam_GSD_1.03237,216,085 - 37,650,773 (-)NCBI
Fras1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052859,368,402 - 9,787,973 (-)NCBI
SpeTri2.0NW_0049366761,870,856 - 2,138,832 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRAS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl873,502,664 - 73,958,083 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1873,502,368 - 73,959,454 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2877,753,520 - 78,204,495 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FRAS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1726,545,048 - 26,992,346 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl726,700,869 - 26,954,352 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660374,899,779 - 5,375,874 (+)NCBIVero_WHO_p1.0
Fras1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475712,532,466 - 12,972,918 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475712,529,475 - 12,973,751 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D14Rat42  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21412,800,200 - 12,800,448 (+)MAPPERmRatBN7.2
Rnor_6.01414,444,994 - 14,445,241NCBIRnor6.0
Rnor_5.01414,386,719 - 14,386,966UniSTSRnor5.0
RGSC_v3.41414,315,728 - 14,315,976RGDRGSC3.4
RGSC_v3.41414,315,729 - 14,315,976UniSTSRGSC3.4
RGSC_v3.11414,315,710 - 14,316,035RGD
Celera1412,857,606 - 12,857,845UniSTS
SHRSP x BN Map146.9RGD
SHRSP x BN Map146.9UniSTS
Cytogenetic Map14p22UniSTS
D14Rat98  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21413,015,311 - 13,015,539 (+)MAPPERmRatBN7.2
Rnor_6.01414,673,206 - 14,673,433NCBIRnor6.0
Rnor_5.01414,613,528 - 14,613,755UniSTSRnor5.0
RGSC_v3.41414,535,071 - 14,535,299RGDRGSC3.4
RGSC_v3.41414,535,072 - 14,535,299UniSTSRGSC3.4
RGSC_v3.11414,535,071 - 14,535,299RGD
Celera1413,068,404 - 13,068,631UniSTS
FHH x ACI Map1414.9399RGD
FHH x ACI Map1414.9399UniSTS
Cytogenetic Map14p22UniSTS
D14Rat79  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21413,077,415 - 13,077,619 (+)MAPPERmRatBN7.2
Rnor_6.01414,734,626 - 14,734,829NCBIRnor6.0
Rnor_5.01414,674,948 - 14,675,151UniSTSRnor5.0
Celera1413,129,481 - 13,129,684UniSTS
SHRSP x BN Map146.9RGD
SHRSP x BN Map146.9UniSTS
Cytogenetic Map14p22UniSTS
D14Rat103  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21412,808,749 - 12,808,976 (+)MAPPERmRatBN7.2
Rnor_6.01414,453,543 - 14,453,769NCBIRnor6.0
Rnor_5.01414,395,268 - 14,395,494UniSTSRnor5.0
RGSC_v3.41414,324,277 - 14,324,505RGDRGSC3.4
RGSC_v3.41414,324,278 - 14,324,505UniSTSRGSC3.4
RGSC_v3.11414,324,277 - 14,324,505RGD
Celera1412,866,147 - 12,866,373UniSTS
SHRSP x BN Map146.9RGD
SHRSP x BN Map146.9UniSTS
Cytogenetic Map14p22UniSTS
D14Mco13  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21413,174,727 - 13,175,095 (+)MAPPERmRatBN7.2
Rnor_6.01414,826,719 - 14,827,086NCBIRnor6.0
Rnor_5.01414,769,262 - 14,769,629UniSTSRnor5.0
RGSC_v3.41414,676,254 - 14,676,622RGDRGSC3.4
RGSC_v3.41414,676,255 - 14,676,622UniSTSRGSC3.4
RGSC_v3.11414,676,254 - 14,676,622RGD
Celera1413,225,369 - 13,225,736UniSTS
Cytogenetic Map14p22UniSTS
RH144158  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21412,881,386 - 12,881,521 (+)MAPPERmRatBN7.2
Rnor_6.01414,536,124 - 14,536,258NCBIRnor6.0
Rnor_5.01414,477,092 - 14,477,226UniSTSRnor5.0
RGSC_v3.41414,399,815 - 14,399,949UniSTSRGSC3.4
Celera1412,936,975 - 12,937,109UniSTS
Cytogenetic Map14p22UniSTS
BF405012  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01414,401,871 - 14,401,969NCBIRnor5.0
Rnor_5.01414,400,561 - 14,400,659NCBIRnor5.0
RGSC_v3.41414,331,752 - 14,331,849UniSTSRGSC3.4
Celera1412,871,993 - 12,872,090UniSTS
RH 3.4 Map14157.07UniSTS
Cytogenetic Map14p22UniSTS
AU048978  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21412,922,320 - 12,922,560 (+)MAPPERmRatBN7.2
Rnor_6.01414,576,926 - 14,577,165NCBIRnor6.0
Rnor_5.01414,517,829 - 14,518,068UniSTSRnor5.0
RGSC_v3.41414,441,160 - 14,441,399UniSTSRGSC3.4
Cytogenetic Map14p22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14381307418274691Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:126
Count of miRNA genes:107
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000002814
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 16 2 2 2 1 1 2 28 15 9 1
Low 24 35 19 16 19 7 10 72 7 20 2 7
Below cutoff 2 3 18 18 3 18 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002814   ⟹   ENSRNOP00000002814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1412,793,599 - 13,200,726 (-)Ensembl
Rnor_6.0 Ensembl1414,439,082 - 14,689,554 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100214   ⟹   ENSRNOP00000093123
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1412,793,599 - 13,200,726 (-)Ensembl
RefSeq Acc Id: NM_001191595   ⟹   NP_001178524
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,793,599 - 13,200,726 (-)NCBI
Rnor_6.01414,438,392 - 14,853,016 (-)NCBI
Rnor_5.01414,380,117 - 14,795,559 (-)NCBI
Celera1412,851,004 - 13,251,138 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091668   ⟹   XP_038947596
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,791,407 - 13,199,871 (-)NCBI
RefSeq Acc Id: XM_039091669   ⟹   XP_038947597
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21412,791,407 - 13,200,862 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178524 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947596 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947597 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL99640 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001178524   ⟸   NM_001191595
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: ENSRNOP00000002814   ⟸   ENSRNOT00000002814
RefSeq Acc Id: XP_038947597   ⟸   XM_039091669
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038947596   ⟸   XM_039091668
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000093123   ⟸   ENSRNOT00000100214
Protein Domains
VWFC

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306516 AgrOrtholog
BioCyc Gene G2FUF-16326 BioCyc
Ensembl Genes ENSRNOG00000002053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002814 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000093123 ENTREZGENE
Ensembl Transcript ENSRNOT00000002814 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000100214 ENTREZGENE
Gene3D-CATH 2.60.40.2030 UniProtKB/TrEMBL
InterPro CalX-like_sf UniProtKB/TrEMBL
  Calx_beta UniProtKB/TrEMBL
  CSPG_rpt UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  Furin_repeat UniProtKB/TrEMBL
  Growth_fac_rcpt UniProtKB/TrEMBL
  VWF_C UniProtKB/TrEMBL
NCBI Gene 289486 ENTREZGENE
Pfam Calx-beta UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
PhenoGen Fras1 PhenoGen
PROSITE CSPG UniProtKB/TrEMBL
  VWFC_1 UniProtKB/TrEMBL
  VWFC_2 UniProtKB/TrEMBL
SMART Calx_beta UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  SM00261 UniProtKB/TrEMBL
  VWC UniProtKB/TrEMBL
  VWC_out UniProtKB/TrEMBL
Superfamily-SCOP Grow_fac_recept UniProtKB/TrEMBL
  SSF141072 UniProtKB/TrEMBL
UniProt F1M3H3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Fras1  Fraser extracellular matrix complex subunit 1  LOC103693728  extracellular matrix protein FRAS1-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103693728  extracellular matrix protein FRAS1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2014-07-09 Fras1  Fraser extracellular matrix complex subunit 1  Fras1  Fraser syndrome 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-17 Fras1  Fraser syndrome 1  Fras1  Fraser syndrome 1 homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fras1  Fraser syndrome 1 homolog (human)   Fras1_predicted  Fraser syndrome 1 homolog (human) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Fras1_predicted  Fraser syndrome 1 homolog (human) (predicted)    Fraser syndrome 1 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Fras1_predicted  Fraser syndrome 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED