Exhibits chemokine activity. Involved in several processes, including response to auditory stimulus; response to gamma radiation; and response to vitamin D. Localizes to the extracellular space. Used to study adult respiratory distress syndrome; myocarditis; proteinuria; renovascular hypertension; and type 1 diabetes mellitus. Biomarker of brain ischemia; encephalitis; and uveitis. Human ortholog(s) of this gene implicated in middle cerebral artery infarction. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; influenza A pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Itraconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], Itraconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA, TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA]
4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA], 4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]
[Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein]
amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], amorolfine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA], acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA]
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium, [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
[CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium, [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
[PTGS2 gene mutant form results in increased susceptibility to [Nanotubes, Carbon co-treated with OVAL protein]] which results in increased expression of CXCL10 mRNA
chrysin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA], chrysin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [cobaltous chloride results in increased secretion of CXCL10 protein]
Cycloheximide inhibits the reaction [TNF protein results in increased expression of CXCL10 protein], Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]]
ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of CXCL10 mRNA], TLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of CXCL10 mRNA]
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA more ...
[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA, isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA]
Estradiol inhibits the reaction [Dimethoate results in increased expression of CXCL10 mRNA], fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dimethoate results in increased expression of CXCL10 mRNA]]
acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA], Allopurinol inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA]
eriodictyol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA], eriodictyol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
ADIPOQ protein inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]], Ethanol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
fulvestrant inhibits the reaction [bazedoxifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]] more ...
[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein more ...
Adjuvants, Immunologic inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein], MYD88 protein affects the reaction [Adjuvants, Immunologic inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein]]
Dinoprostone inhibits the reaction [Indomethacin inhibits the reaction [Roflumilast inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL10 protein]]], Indomethacin inhibits the reaction [Roflumilast inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL10 protein]]
Itraconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], Itraconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], Ketoconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
acteoside promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein], Quercetin promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein]
[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein more ...
luliconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], luliconazole inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
Luteolin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA], Luteolin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]
[Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein]
[Lipopolysaccharides co-treated with Melatonin] results in decreased expression of CXCL10 mRNA, Melatonin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
[MT3 protein affects the susceptibility to methylmercuric chloride] which affects the expression of CXCL10 mRNA, MT3 protein affects the reaction [methylmercuric chloride results in increased expression of CXCL10 mRNA]
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CXCL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein], Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]] more ...
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA more ...
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [nickel sulfate inhibits the reaction [macrophage stimulatory lipopeptide 2 results in increased secretion of CXCL10 protein]]
Fulvestrant inhibits the reaction [Ospemifene inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]] more ...
IFNG protein promotes the reaction [Acetaminophen results in increased expression of CXCL10 mRNA], KLRB1C protein promotes the reaction [Acetaminophen results in increased expression of CXCL10 mRNA]
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CXCL10 protein
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CXCL10 mRNA, NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CXCL10 mRNA]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA, IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA]
[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein more ...
Dinoprostone inhibits the reaction [Indomethacin inhibits the reaction [Roflumilast inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL10 protein]]] more ...
[Protein Kinase Inhibitors results in decreased activity of IRAK4 protein] inhibits the reaction [resiquimod promotes the reaction [IRF5 protein binds to CXCL10 promoter]] more ...
[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of and results in increased secretion of CXCL10 protein
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA], Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein]
[Protein Kinase Inhibitors results in decreased activity of IRAK4 protein] inhibits the reaction [resiquimod promotes the reaction [IRF5 protein binds to CXCL10 promoter]] more ...
Dinoprostone inhibits the reaction [Indomethacin inhibits the reaction [Roflumilast inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL10 protein]]] more ...
[Gold co-treated with Silicon Dioxide] results in increased secretion of CXCL10 protein, GREM1 protein inhibits the reaction [Silicon Dioxide results in increased expression of CXCL10 protein]
Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL10 mRNA], Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL10 protein]
[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CXCL10 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CXCL10 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein], Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]
Tamoxifen inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA], Tamoxifen inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein]
Terbinafine inhibits the reaction [Biological Products results in increased expression of CXCL10 mRNA], Terbinafine inhibits the reaction [Biological Products results in increased expression of CXCL10 protein]
Valsartan inhibits the reaction [AGT protein results in increased expression of CXCL10 mRNA], Valsartan inhibits the reaction [AGT protein results in increased expression of CXCL10 protein]
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA more ...
[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA more ...
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Target capture sequencing of exons and conserved non-coding sequences. Provided by: Dr. Mikita Suyama (Kyushu University) and Dr. Takashi Kuramoto (Kyoto University)
Publications:
Yoshihara M, etal., Genom Data. 2016 Nov 14;10:155-157. eCollection 2016 Dec.
Gene-Chemical Interaction Annotations
