Abcg3l2 (ATP-binding cassette, subfamily G (WHITE), member 3-like 2) - Rat Genome Database

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Gene: Abcg3l2 (ATP-binding cassette, subfamily G (WHITE), member 3-like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Abcg3l2
Name: ATP-binding cassette, subfamily G (WHITE), member 3-like 2
RGD ID: 1359703
Description: Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-binding cassette, sub-family G (WHITE), member 3-like 2; LOC102552852; LOC360910; similar to ATP-binding cassette transporter ABCG3; uncharacterized LOC102552852
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8144,798,053 - 4,847,424 (-)NCBIGRCr8
mRatBN7.2144,493,259 - 4,538,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,493,262 - 4,533,306 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0145,568,023 - 5,609,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0145,526,681 - 5,544,954 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0145,628,496 - 5,632,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4145,573,147 - 5,613,575 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1145,573,149 - 5,613,575 (-)NCBI
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
724541Niddm53Non-insulin dependent diabetes mellitus QTL 530.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1439578789393298Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14111334906Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat

Markers in Region
BF407350  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0145,618,477 - 5,618,588NCBIRnor5.0
Rnor_5.0145,546,758 - 5,546,869NCBIRnor5.0
Rnor_5.0145,731,490 - 5,731,601NCBIRnor5.0
RGSC_v3.4145,615,391 - 5,615,501UniSTSRGSC3.4
RGSC_v3.4145,569,572 - 5,569,682UniSTSRGSC3.4
Celera144,651,241 - 4,651,351UniSTS
RH 3.4 Map14126.5UniSTS
Cytogenetic Map14p22UniSTS
RH134900  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera144,748,515 - 4,748,960UniSTS
Celera144,978,678 - 4,979,126UniSTS
RH 3.4 Map1483.0UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000079795   ⟹   ENSRNOP00000068906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl144,493,939 - 4,533,306 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106658   ⟹   ENSRNOP00000082989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl144,493,262 - 4,533,306 (-)Ensembl
RefSeq Acc Id: NM_001419101   ⟹   NP_001406030
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8144,798,053 - 4,838,117 (-)NCBI
mRatBN7.2144,493,259 - 4,533,325 (-)NCBI
RefSeq Acc Id: XM_039092155   ⟹   XP_038948083
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8144,798,053 - 4,847,424 (-)NCBI
mRatBN7.2144,493,259 - 4,538,264 (-)NCBI
RefSeq Acc Id: XM_063273322   ⟹   XP_063129392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8144,798,053 - 4,832,807 (-)NCBI
RefSeq Acc Id: XM_063273323   ⟹   XP_063129393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8144,798,053 - 4,827,541 (-)NCBI
RefSeq Acc Id: XP_038948083   ⟸   XM_039092155
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZW97 (UniProtKB/TrEMBL),   A0A8I6A0D0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000068906   ⟸   ENSRNOT00000079795
Ensembl Acc Id: ENSRNOP00000082989   ⟸   ENSRNOT00000106658
RefSeq Acc Id: NP_001406030   ⟸   NM_001419101
- UniProtKB: A0A8I6A0D0 (UniProtKB/TrEMBL),   A0A8I5ZW97 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129392   ⟸   XM_063273322
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JTZ9 (UniProtKB/TrEMBL),   Q5U314 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129393   ⟸   XM_063273323
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JTZ9 (UniProtKB/TrEMBL)
Protein Domains
ABC transporter   ABC-2 type transporter transmembrane

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359703 AgrOrtholog
BioCyc Gene G2FUF-16543 BioCyc
Ensembl Genes ENSRNOG00000064381 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000070774 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079795.2 UniProtKB/TrEMBL
  ENSRNOT00000106658.1 UniProtKB/TrEMBL
  ENSRNOT00000115444.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7096429 IMAGE-MGC_LOAD
InterPro ABC_2_trans UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABCG_transporters UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
MGC_CLONE MGC:93691 IMAGE-MGC_LOAD
NCBI Gene 360910 ENTREZGENE
PANTHER ABC TRANSPORTER G FAMILY MEMBER 28 UniProtKB/TrEMBL
  ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 3 UniProtKB/TrEMBL
Pfam ABC2_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PhenoGen Abcg3l2 PhenoGen
PROSITE ABC_TRANSPORTER_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000064381 RatGTEx
  ENSRNOG00000070774 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JTZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZW97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0D0 ENTREZGENE, UniProtKB/TrEMBL
  Q5U314 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Abcg3l2  ATP-binding cassette, subfamily G (WHITE), member 3-like 2  LOC102552852  uncharacterized LOC102552852  Data merged from RGD:7686863 737654 PROVISIONAL
2013-12-18 LOC102552852  uncharacterized LOC102552852      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-11-16 Abcg3l2  ATP-binding cassette, subfamily G (WHITE), member 3-like 2  Abcg3l2  ATP-binding cassette, sub-family G (WHITE), member 3-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-20 Abcg3l2  ATP-binding cassette, sub-family G (WHITE), member 3-like 2  LOC360910  similar to ATP-binding cassette transporter ABCG3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 LOC360910  similar to ATP-binding cassette transporter ABCG3      Symbol and Name status set to provisional 70820 PROVISIONAL