Niddm53 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Niddm53 (Non-insulin dependent diabetes mellitus QTL 53) Rattus norvegicus

Symbol: Niddm53
Name: Non-insulin dependent diabetes mellitus QTL 53
RGD ID: 724541
Also known as: Nidd16/of
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0144,833,233 - 10,729,268RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0144,830,815 - 10,676,655RGDRnor5.0
RGSC_v3.4144,895,894 - 10,340,377RGDRGSC3.4
RGSC_v3.1144,895,895 - 10,340,272RGD
Cross Type: intercross
Strains Crossed: F344/DuCrlCrlj OLETF/Got 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
1. Yamada T, etal., Exp Anim 2001 Apr;50(2):115-23.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
9475400LOC103693714uncharacterized LOC1036937141449490494949664Rat
1592829Zfp326zinc finger protein 3261449985305006759Rat
1592829Zfp326zinc finger protein 3261450167645036663Rat
1309601Lrrc8dleucine rich repeat containing 8 VRAC subunit D1450856065194808Rat
1306585Lrrc8cleucine rich repeat containing 8 VRAC subunit C1452836555378738Rat
11466948LOC108352696uncharacterized LOC1083526961453870205399035Rat
1563429Lrrc8bleucine rich repeat containing 8 VRAC subunit B1454148725482004Rat
7571368LOC102548248calphotin-like1454496475482006Rat
11472364LOC108352838uncharacterized LOC1083528381454954885510446Rat
11381376LOC108352839uncharacterized LOC1083528391455020045506673Rat
9417037LOC103690063ATP-binding cassette sub-family G member 3-like1455379095556242Rat
1359703Abcg3l2ATP-binding cassette, subfamily G (WHITE), member 3-like 21455680235609333Rat
1588538Abcg3l4ATP-binding cassette, subfamily G (WHITE), member 3-like 41455680235746903Rat
9294101LOC103690086uncharacterized LOC1036900861456423575646406Rat
1564709Abcg3l3ATP-binding cassette, subfamily G (WHITE), member 3-like 31457333616104164Rat
7593373LOC102556623uncharacterized LOC1025566231457587415761039Rat
7646169LOC102554737guanylate-binding protein 6-like1458357315848548Rat
1587144LOC679539similar to ubiquitin-conjugating enzyme E2 variant 11458376345839362Rat
2325094LOC100359633guanylate binding protein 111458486215859566Rat
6486058LOC100912618ubiquitin-conjugating enzyme E2 variant 1-like1458673505869085Rat
7637289LOC102554096guanylate-binding protein 6-like1458692975873310Rat
6503480LOC100909418NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like1458930165893501Rat
1561523Gbp6guanylate binding protein family member 61459275685954923Rat
1565568Abcg3ATP-binding cassette, subfamily G (WHITE), member 31459719846053039Rat
9386530LOC103692562uncharacterized LOC1036925621460570266058455Rat
2324613LOC100366030rCG37858-like1461014536148925Rat
11430399LOC108348123zinc finger protein 431-like1461739476227328Rat
7721775LOC102554485zinc finger protein 14-like1461818556201134Rat
2301011Zfp951zinc finger protein 9511462807676284145Rat
6502699Znf442zinc finger protein 4421462984296303135Rat
7528373LOC10254909560S ribosomal protein L38-like1463084426308707Rat
7686608LOC102548800zinc finger protein 14-like1463276936332168Rat
7711909LOC102554913zinc finger protein 120-like1463553006359758Rat
7672026LOC102555309zinc finger protein 120-like1463824426384331Rat
7616489LOC102548714zinc finger protein 709-like1463824426395315Rat
7671160LOC102555406zinc finger protein 120-like1464087446411146Rat
7621998LOC102555488zinc finger protein 120-like1464138436416590Rat
11440926LOC108352837uncharacterized LOC1083528371464331236438620Rat
7551108LOC102548396zinc finger protein 791-like1464664436472122Rat
1303294Abcg3l1ATP-binding cassette, subfamily G (WHITE), member 3-like 11464886556541220Rat
11490910LOC108352840uncharacterized LOC1083528401465412916542724Rat
1583596LOC679894similar to THO complex subunit 2 (Tho2)1465619626601906Rat
1559992Pkd2polycystin 2, transient receptor potential cation channel1466020046645257Rat
9351689LOC103693722uncharacterized LOC1036937221466140946616310Rat
3752Spp1secreted phosphoprotein 11466736866679965Rat
6499958LOC100910198uncharacterized LOC1009101981467807526792085Rat
71036Mepematrix extracellular phosphoglycoprotein1467820116793561Rat
2855Ibspintegrin-binding sialoprotein1468012006813987Rat
2508Dmp1dentin matrix acidic phosphoprotein 11468898516923961Rat
11423237LOC108352697uncharacterized LOC1083526971469072366930678Rat
2525Dsppdentin sialophosphoprotein1469269726933079Rat
2531Sparcl1SPARC like 11469942617025309Rat
9372188LOC103692564uncharacterized LOC1036925641469973106999522Rat
2323137LOC100359907secretory calcium-binding phosphoprotein proline-glutamine rich 1-like1470267697035539Rat
1359522Nudt9nudix hydrolase 91470368097054739Rat
1303235Hsd17b11hydroxysteroid (17-beta) dehydrogenase 111470547247104567Rat
11375110LOC108352698uncharacterized LOC1083526981470792967089205Rat
1359553Hsd17b13hydroxysteroid (17-beta) dehydrogenase 131471135447128218Rat
1304685Klhl8kelch-like family member 81471695177215025Rat
1307940Aff1AF4/FMR2 family, member 11472228837384916Rat
6499531LOC100910240tyrosine-protein phosphatase non-receptor type 13-like1474004267415706Rat
6499131LOC100910270uncharacterized LOC1009102701475059127514158Rat
1564576Aff1-as1AFF1 antisense RNA 11475811897636823Rat
727800Slc10a6solute carrier family 10 member 61476180227682377Rat
7718381LOC102546454uncharacterized LOC1025464541476475977648369Rat
7702897LOC102546534uncharacterized LOC1025465341476579067659941Rat
1563360Ptpn13protein tyrosine phosphatase, non-receptor type 131476885517863664Rat
1560413Ndufb4l1-ps1NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4-like 1, pseudogene 11479492177949662Rat
11392357LOC108352699uncharacterized LOC1083526991479731427998126Rat
3663Mapk10mitogen activated protein kinase 101480799558371508Rat
11372248LOC10835270040S ribosomal protein S25 pseudogene1480899688092579Rat
9132166LOC103692565cytochrome c oxidase protein 20 homolog pseudogene1481489968150347Rat
1306669Arhgap24Rho GTPase activating protein 241483832118600526Rat
11483305LOC108352703uncharacterized LOC1083527031484211318423672Rat
11391501LOC108352702uncharacterized LOC1083527021484323188438833Rat
11463885LOC108352701uncharacterized LOC1083527011485100958521902Rat
7632243LOC102549277uncharacterized LOC1025492771488129398829148Rat
11416353LOC108352704uncharacterized LOC1083527041488941488900203Rat
9130199LOC103692566uncharacterized LOC1036925661489559968968768Rat
1560931RGD1560931similar to proliferating cell nuclear antigen1490235589041346Rat
1597134LOC364103similar to TBC1 domain family, member 11490841569085788Rat
1307097Wdfy3WD repeat and FYVE domain containing 31491694099384835Rat
9474183LOC103693724uncharacterized LOC1036937241492321569246340Rat
9338365LOC103693723multiple epidermal growth factor-like domains protein 61493133009316302Rat
621185Cds1CDP-diacylglycerol synthase 11493965119456964Rat
11389755LOC108352705uncharacterized LOC1083527051494572249508908Rat
11395525LOC108352707uncharacterized LOC1083527071495248099531320Rat
11482723LOC108352706uncharacterized LOC1083527061495319829533431Rat
69318Nkx6-1NK6 homeobox 11495552649562197Rat
1597133LOC364105hypothetical LOC3641051498428669843177Rat
7589278LOC102550272uncharacterized LOC102550272141005330710061978Rat
1585864LOC680925similar to SET protein (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) (Liver regeneration-related protein LRRGR00002)141011288810123723Rat
11441489LOC108352708uncharacterized LOC108352708141029636010297735Rat
11478148LOC108352709uncharacterized LOC108352709141030934710326974Rat
1565703Gpat3glycerol-3-phosphate acyltransferase 3141034328710396565Rat
1305287Abraxas1abraxas 1, BRCA1 A complex subunit141042467410439010Rat
1307997Mrps18cmitochondrial ribosomal protein S18C141044069110446909Rat
1560216Helqhelicase, POLQ-like141044698110491042Rat
7539914LOC10255061760S ribosomal protein L7a-like141045903910460667Rat
11467926LOC108352710uncharacterized LOC108352710141052052010526280Rat
61969Hpseheparanase141053435810576686Rat
1306722Coq2coenzyme Q2, polyprenyltransferase141058110210601093Rat
2322973LOC100363472nuclear receptor-binding factor 2-like141062410110625913Rat
9216872LOC103693725ubiquitin-conjugating enzyme E2 variant 2 pseudogene141068553910686410Rat
1308102Plac8placenta associated 8141069279910714556Rat
1302952Cops4COP9 signalosome subunit 4141071886310749134Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33937D14Mit111431448781624878301Ratregion
36053D14Rat41341497564359756556Ratregion
37030D14Rat3159141072909810729268Ratregion
36536D14Rat11441448332334833374Ratregion
39860D14Rat73194141014787910148088Ratregion
39204D14Rat542201450976675097856Ratregion
41984D14Arb12721468018146802085Ratregion
41438D14Rat721731480586788058862Ratregion
42386D14Rat1422461471096567109887Ratregion
45143D14Got72441452058365206079Ratregion
45144D14Got81561457039865704140Ratregion
45146D14Got101721472512397251410Ratregion
60083D14Got92211473537337353953Ratregion
45306D14Got171451490969099097053Ratregion
60056D14Got111171472973207297436Ratregion
60057D14Got14171141008118410081354Ratregion
1629285D14Got1572441449894274989670Ratregion
1629971D4Got270981455206435520740Ratregion
1635099D14Got1471001491547529154849Ratregion
1634005D14Wox221631470249587025120Ratregion
5036053UniSTS:46346461141070986810709928Ratregion
5036053UniSTS:463464611475094777509537Ratregion
5038934RH1274171941476888717689064Ratregion
5035625D21S1917471470087917009374Ratregion
5035709SPARCL1961470196737019768Ratregion
7206154UniSTS:5322818211483674008368220Ratregion
5026266RH131554180141044099710441260Ratregion
5028855RH1425862121465767506576961Ratregion
5028887RH1427031441479340637934206Ratregion
5034205RH141764220141057531210575531Ratregion
5034221RH141824180141056921010569390Ratregion
5026780RH133501181141034339710343577Ratregion
5029533AA8596161981493845529384749Ratregion
5035352AW5299131941470123667012559Ratregion
5032705RH1349931931460587386058930Ratregion
5035304AI1032852021477040467704247Ratregion
5025004AA690179124141057512410575247Ratregion
5030323BF4023272471488942088894454Ratregion
5027771RH946781651466738106673974Ratregion
5030801BE1202001741481212218121394Ratregion
5030801BE1202001741474659407466113Ratregion
5028448AI3261151771452877845287960Ratregion
5031073BE1157921721492621329262303Ratregion
5054923RH1435021611470976217097781Ratregion
5054947RH1435171911465992886599478Ratregion
5051823RH946791891468015126801699Ratregion
5051827RH946812491468920106892258Ratregion
5057424BF418328129141040490410405032Ratregion
5057432BF4184321381454170615417198Ratregion
5059510BE0971391951467918576792051Ratregion
5057884BF392886961483718098371904Ratregion
5058838BF393702911482933238293413Ratregion
505217310.MHAa98e10.seq1671478626607862826Ratregion
5059104BE1028251651471712857171449Ratregion
5054265RH1431251541460167116016864Ratregion
5054265RH1431251541458033785803532Ratregion
5040798RH1284891921471041847104375Ratregion
5043326RH1299621631493755729375733Ratregion
5045468RH1311951871471043547104540Ratregion
5041490RH128886190141057641210576601Ratregion
5044992RH1309211991472230717223269Ratregion
5049180RH1333312041470249647025167Ratregion
5046692RH1319001851483680528368236Ratregion
5049670RH1336141801465621396562320Ratregion
5042536RH1294942181466738186674035Ratregion
5042118RH1292501921461039006104091Ratregion
5041012RH1286122201490232819023506Ratregion
5072636RH1369642101466736926673901Ratregion
5073996RH1377591991483515028351700Ratregion
5075674RH1387311931449979014998093Ratregion
5072404RH1368291221484385608438681Ratregion
5074532RH1380712091450036535003855Ratregion
5074716RH1381771231476830567683178Ratregion
5077010RH1395072191483609108361128Ratregion
5077148RH1395892171454176965417913Ratregion
5076322RH1391081281472147287214855Ratregion
5079648RH1411232121465806096582018Ratregion
5077328RH1396932141484385608438773Ratregion
5076370RH1391362351460778696078104Ratregion
5077406RH1397382191471278877128105Ratregion
5078428RH1403372371483609008361136Ratregion
5078608RH1404422491454176645417913Ratregion
5072974RH137161186141058372710583912Ratregion
5080446RH1415831801466021476602326Ratregion
5070556RH1345691931483834768383668Ratregion
5073984RH1377521781470049527005130Ratregion
5074166RH1378602441472139827214225Ratregion
5071836RH1353132201453258905326109Ratregion
5073646RH1375561241453154615315584Ratregion
5063348BE1075791761467820576782232Ratregion
5067074AU0479812981494062739406570Ratregion
5067090AU0479701431476530177653159Ratregion
5067090AU0479701431476408917641033Ratregion
5068972AU046808141141020376510203900Ratregion
5065394BE115323150141056320910563358Ratregion
5060846BF3892011241450697415069864Ratregion
5062770AW5343921531455020605502212Ratregion
5061960BI2944861731466037836603955Ratregion
5060542BE1103021651466572686657432Ratregion
5062528BI2889221581451878625188019Ratregion
5061040BF4017021571454626505462806Ratregion
5086494BQ2063301991451824315182629Ratregion
5089455AU0491661801451335315133710Ratregion
5083769AI1054321361470510107051145Ratregion
5083861AI230820180141071171710711895Ratregion
5083861AI2308201801475113267511504Ratregion
5082393BI274688172141071899210719163Ratregion
5082393BI2746881721475186017518772Ratregion
5088399AU0485461851473536787353862Ratregion
5088399AU0485461851473535047353862Ratregion
5081210RH1420282181466181166618333Ratregion
5085463BE0969012011470939437094141Ratregion
5085491BE0969671651453280885328252Ratregion
5082651BE1199301581472889017289058Ratregion
5086094BF3877111611450028225002982Ratregion
5507719G392001751480160848016258Ratregion
5504636PMC316977P23451466742266674570Ratregion
5505322Aff115971472917097293305Ratregion
5506171AFM350VD14381492760139276645Ratregion
5506602UniSTS:2804071841466754266676829Ratregion
5499499stSG6024345051476606567661495Ratregion
5500895D21S12701160141054945110550610Ratregion
Position Markers

Flank 1: (D14Rat1)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0144,833,233 - 4,833,374NCBI
Rnor_5.0144,830,815 - 4,830,956UniSTS
RGSC_v3.4144,895,894 - 4,896,036RGD
RGSC_v3.4144,895,895 - 4,896,036UniSTS
RGSC_v3.1144,895,895 - 4,896,036RGD
Celera143,806,493 - 3,806,634UniSTS
RH 3.4 Map1475.7UniSTS
RH 3.4 Map1475.7RGD
RH 2.0 Map1490.7RGD
SHRSP x BN Map142.29RGD
FHH x ACI Map141.33RGD
Flank 2: (D14Rat3)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01410,729,098 - 10,729,268NCBI
Rnor_5.01410,676,485 - 10,676,655UniSTS
RGSC_v3.41410,340,102 - 10,340,272UniSTS
RGSC_v3.41410,339,971 - 10,340,377RGD
RGSC_v3.11410,340,102 - 10,340,272RGD
Celera149,197,754 - 9,197,924UniSTS
Cytogenetic Map14p22UniSTS
RH 3.4 Map14152.08RGD
RH 3.4 Map14152.08UniSTS
RH 2.0 Map14162.0RGD
SHRSP x BN Map144.62RGD


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14222782512680613Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14222782519230541Rat
724541Niddm53Non-insulin dependent diabetes mellitus QTL 530.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14483323310729268Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14483323319909932Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14483323319909932Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14483323323004027Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14483323326466248Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14483323333040042Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm53

RGD Curation Notes
Note Type Note Reference
qtl_cross_type intercross  
qtl_general markers are only 2 cM apart; involved in epistatic interactions with Niddm 52; Niddm55 and Niddm56 619670