Pramel34 (PRAME like 34) - Rat Genome Database

Name: Pramel34
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Pramel34 (PRAME like 34) Rattus norvegicus

Analyze

Symbol:

Pramel34 (Ensembl: LOC685782)

Name:

PRAME like 34 (Ensembl:similar to PRAME family member 9)

RGD ID:

1590186

Description:

FOUND IN cytoplasm (inferred); INTERACTS WITH 1,2-dichloroethane (ortholog); 2,3',4,4',5-Pentachlorobiphenyl (ortholog); 4,4'-sulfonyldiphenol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC685782; PRAME family member 12-like; PRAME family member 20-like; similar to PRAME family member 9

RGD Orthologs

Mouse

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	14,153,759 - 14,156,758 (-)	NCBI		GRCr8
mRatBN7.2	14	13,850,057 - 13,852,806 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	13,850,057 - 13,852,806 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	14	15,896,765 - 15,899,917 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	15,824,448 - 15,827,197 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	15,654,685 - 15,657,434 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	13,874,785 - 13,877,937 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

dimethylarsinic acid (ISO)

methylarsonic acid (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Pramel34
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	14,153,759 - 14,156,758 (-)	NCBI		GRCr8
mRatBN7.2	14	13,850,057 - 13,852,806 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	13,850,057 - 13,852,806 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	14	15,896,765 - 15,899,917 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	14	15,824,448 - 15,827,197 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	15,654,685 - 15,657,434 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	14	13,874,785 - 13,877,937 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

Pramel34
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	93,783,041 - 93,819,368 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	93,783,056 - 93,819,410 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	93,635,182 - 93,671,509 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	93,634,993 - 93,671,551 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	94,064,211 - 94,100,489 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	94,710,197 - 94,746,713 (-)	NCBI		MGSCv36	mm8
Cytogenetic Map	5	E3	NCBI
cM Map	5	47.29	NCBI

Variants

Variants in Pramel34
16 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1217606	16960180	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	3813074	18274691	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3813074	18274691	Rat
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3813074	21217635	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3813074	24531477	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3813074	30767156	Rat
1581500	Renag1	Renal agenesis QTL 1			kidney development trait (VT:0000527)	percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)	14	8170668	68298175	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8267090	53267090	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8267090	53267090	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9088978	39057237	Rat
2302277	Gluco38	Glucose level QTL 38	5.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	28035204	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
631212	Bw5	Body weight QTL5	5.43		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	11030812	30320092	Rat

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001065244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_002724946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000117315 ⟹ ENSRNOP00000090792

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	13,850,057 - 13,852,806 (-)	Ensembl

RefSeq Acc Id:

XM_001065244 ⟹ XP_001065244

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	14,153,759 - 14,156,758 (-)	NCBI
mRatBN7.2	14	13,850,057 - 13,852,806 (-)	NCBI
Rnor_6.0	14	15,896,765 - 15,899,917 (+)	NCBI
Rnor_5.0	14	15,824,448 - 15,827,197 (+)	NCBI
RGSC_v3.4	14	15,654,685 - 15,657,434 (-)	RGD

Sequence:

show sequence

ATGAGTATTCAGACTCCACCCACACTCCAGGAGCTGGCAGTGCGTAGTCTGCTGAGAAATGAGG
CCATGGCCATGTCCTATCTTGGGGAGCTCCCTGCTGTGCTCTTCCCAGAAGTGTTCAAGGAGGC
ATTTGCTAGAAGACACATCAACATAGTGAAGGAAATGGTGGCAGTTTGGCCTTTCCCCCGTATC
GCAGTGGGGGCACTGATGGAGACACCCAACCTGGAAATCTACAAGGCTTTGCTAGATGGAGTAG
ACATGGGACTGAAAGAAGAGTTTCAGCACAGGGAGAAAAATCTTAAGGTCTTGGACCTGAGAAA
TGTTCACCATACCTTCTGGAACATATGTGCTGATGAAAGGAAGAGTGGCTGTTCATCAGAGACA
CTGAACAAGAAGCAAGTAGTGAAGGTCTTTCCCAGATATGCACTGAGGCAGCGTCTGAGGGTCA
TAGTTGACCTGTGCCTCAAACTAAGCCTCAATAAAACACAAGCATACTTCTTGAATTGGGTCCA
GCAAAGAAAGAGCTCCCTGCATTTCTGCTGTATAAAGATGACAATCTGGTCTATCCCATTCCAA
GATATCAAAGGGATCTTGAATGTTTTTGACAGAGAGCACATTGCAGAATTAGAACTGCATACCA
AGTGGACTCTGTTACAGCTGAGACATTTTGCTCACTACTTTGGACAGATGAGAAATCTTCGCAA
ACTTATCCTGGCACCCCTCCATATGACAACCTTCTCTACAATTGAAAGAACAAGGGTCAGAGAA
ACCAGGAGTGTCAACAATTTTATTTCTCAGTTCTCTCAATTCAACTGTCTGCAGCATCTCTTCA
TTAGTCAAGTTCATTTCCTCAGAGTCCAGATGCATCAGATTTTAGGGTTCCTGATGACACGCTT
GGAGACCCTCTCCATCACTAATTACATAACTTCACAGAGAGACTTGAATTCCTTGTCCTGCTGT
GAGAGCCTCTTTCAGTTAAAACATCTGGATCTGAGAGGAACAGTCTTGTATTCACTGGATCTTA
TGCCTCTGAGAGCTCTGCTACATAAAGTGGAAGACACGCTAGAGATTCTGCAATTAGAGGGGTG
TAGAATGATTGACTCACAACTCAATGCCCTCCTTCCTGCCCTTAGACAATGCTCTCAGCTCACC
AAGATCAACCTCTACAAAAATGACTTCTCCATGCACATCCTAATGGCCCTTTTGCAGCACACAG
ACAACTGGAACAAGATCGTTGTGGAACAATACCCTGCTCCTCTGGAGTGCTATGAGTTGTCCCA
TGTCTCCAGAGAAAGATTTTCACAACTTTGTTCTCAGCTCATGGCTACACTCAGGGCAATAAGG
CAGCCCAAGAACATCGCCTTTGCTTCAAAAATGTGCCAAAGATGTGCCAAGCACTGTGTCTATA
CCCAGGTGACCAGACTTTGCAGGTGCTGGCATTAATTTGGGAAATACTACTTCTGGATTGGAAT
AAACAACAGGATTGGGAAACATCTCTCATGTGGGGTTCTTCGAGATTGTGGCTTTTGACACTGC
TCAGATGTTTGGGGAAAAATTATGTACAGAGACTGGGATCTTGCAGGGCAAACGTGTCATGGGG
AACAGTGGTATCTATTGTGGGACCAGGGTCCTTTTGGAGTCAGTATCAGAGTTTGGCTGGACAT
AGTAAATAAATGCTTTGCTGTATACTGATAAACCTGGATGTTCTCTCTCTGGGGTCTTTAATTG
TTACAACTTCACTACCAGGTTCTGAGTCAGGAAGTTTCAATAGGTCCAGGAATAGAAAGATACT
GGTATTTTATGACTGTATCAAACTTCCAGGTGAAATTGACACAAAATAAAAATG

hide sequence

Protein Sequences


Protein RefSeqs	XP_001065244	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000090792.1

RefSeq Acc Id:

XP_001065244 ⟸ XM_001065244

- Sequence:

show sequence

MSIQTPPTLQELAVRSLLRNEAMAMSYLGELPAVLFPEVFKEAFARRHINIVKEMVAVWPFPRI
AVGALMETPNLEIYKALLDGVDMGLKEEFQHREKNLKVLDLRNVHHTFWNICADERKSGCSSET
LNKKQVVKVFPRYALRQRLRVIVDLCLKLSLNKTQAYFLNWVQQRKSSLHFCCIKMTIWSIPFQ
DIKGILNVFDREHIAELELHTKWTLLQLRHFAHYFGQMRNLRKLILAPLHMTTFSTIERTRVRE
TRSVNNFISQFSQFNCLQHLFISQVHFLRVQMHQILGFLMTRLETLSITNYITSQRDLNSLSCC
ESLFQLKHLDLRGTVLYSLDLMPLRALLHKVEDTLEILQLEGCRMIDSQLNALLPALRQCSQLT
KINLYKNDFSMHILMALLQHTDNWNKIVVEQYPAPLECYELSHVSRERFSQLCSQLMATLRAIR
QPKNIAFASKMCQRCAKHCVYTQVTRLCRCWH

hide sequence

RefSeq Acc Id:

ENSRNOP00000090792 ⟸ ENSRNOT00000117315

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-16309	BioCyc
Ensembl Genes	ENSRNOG00000067111	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000117315.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	685782	ENTREZGENE
PANTHER	D5ERTD577E PROTEIN-RELATED	UniProtKB/TrEMBL
	SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3	UniProtKB/TrEMBL
PhenoGen	Pramel34	PhenoGen
RatGTEx	ENSRNOG00000067111	RatGTEx
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
UniProt	A0A8I6ACJ9_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-04-25	Pramel34	PRAME like 34	LOC685782	similar to PRAME family member 9	Name and Symbol changed	629549	APPROVED
2008-01-09	LOC685782	similar to PRAME family member 9	LOC684407	similar to PRAME family member 9	Data merged from RGD:1590359	1643240	APPROVED
2006-11-20	LOC685782	similar to PRAME family member 9			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC684407	similar to PRAME family member 9			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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