Cdkl2 (cyclin dependent kinase like 2) - Rat Genome Database

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Gene: Cdkl2 (cyclin dependent kinase like 2) Rattus norvegicus
Analyze
Symbol: Cdkl2
Name: cyclin dependent kinase like 2
RGD ID: 1309625
Description: Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CDKL2 (cyclin dependent kinase like 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cyclin-dependent kinase-like 2; cyclin-dependent kinase-like 2 (CDC2-related kinase); LOC305242
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21416,027,381 - 16,063,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1416,028,363 - 16,063,252 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1416,042,194 - 16,064,889 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01417,361,086 - 17,383,777 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01416,053,214 - 16,075,904 (+)NCBIRnor_WKY
Rnor_6.01417,530,170 - 17,565,950 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,531,398 - 17,565,950 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01417,448,431 - 17,483,326 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,598,862 - 17,621,559 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11417,598,861 - 17,621,556 (+)NCBI
Celera1415,421,440 - 15,444,142 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IEA,ISO)
cytoplasm  (IEA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:24270810   PMID:25931508  


Genomics

Comparative Map Data
Cdkl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21416,027,381 - 16,063,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1416,028,363 - 16,063,252 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1416,042,194 - 16,064,889 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01417,361,086 - 17,383,777 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01416,053,214 - 16,075,904 (+)NCBIRnor_WKY
Rnor_6.01417,530,170 - 17,565,950 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,531,398 - 17,565,950 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01417,448,431 - 17,483,326 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,598,862 - 17,621,559 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11417,598,861 - 17,621,556 (+)NCBI
Celera1415,421,440 - 15,444,142 (+)NCBICelera
Cytogenetic Map14p22NCBI
CDKL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38475,576,496 - 75,630,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl475,576,496 - 75,630,716 (-)EnsemblGRCh38hg38GRCh38
GRCh37476,501,706 - 76,555,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36476,720,728 - 76,774,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 34476,861,525 - 76,912,750NCBI
Celera473,797,824 - 73,851,860 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef472,248,538 - 72,302,292 (-)NCBIHuRef
CHM1_1476,478,463 - 76,532,392 (-)NCBICHM1_1
T2T-CHM13v2.0478,916,642 - 78,970,655 (-)NCBIT2T-CHM13v2.0
Cdkl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,153,933 - 92,198,479 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,153,933 - 92,191,742 (-)EnsemblGRCm39 Ensembl
GRCm38592,006,074 - 92,043,042 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,006,074 - 92,043,883 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,435,101 - 92,472,044 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36593,081,275 - 93,118,218 (-)NCBIMGSCv36mm8
Celera590,149,284 - 90,186,200 (-)NCBICelera
Cytogenetic Map5E2NCBI
Cdkl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554741,513,391 - 1,550,385 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554741,514,566 - 1,550,120 (-)NCBIChiLan1.0ChiLan1.0
CDKL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1454,411,593 - 54,463,143 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl454,415,305 - 54,458,111 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0448,575,933 - 48,628,916 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CDKL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132158,140 - 206,860 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32159,332 - 202,617 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3241,675,076 - 41,723,801 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.032181,705 - 230,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32181,705 - 230,438 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132178,638 - 227,284 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032136,664 - 183,333 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03239,987,143 - 40,035,866 (+)NCBIUU_Cfam_GSD_1.0
Cdkl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528511,886,680 - 11,925,061 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936598339,384 - 377,728 (+)EnsemblSpeTri2.0
SpeTri2.0NW_004936598337,701 - 377,091 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDKL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl871,231,152 - 71,260,815 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1871,231,148 - 71,260,902 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2875,370,838 - 75,398,993 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDKL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1724,087,771 - 24,137,348 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl724,087,771 - 24,137,214 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660372,415,240 - 2,464,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdkl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624730219,730 - 277,898 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624730219,722 - 279,866 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdkl2
94 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:100
Interacting mature miRNAs:111
Transcripts:ENSRNOT00000046771, ENSRNOT00000050038
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)14381307418274691Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat

Markers in Region
BF397208  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21416,033,628 - 16,033,737 (+)MAPPERmRatBN7.2
Rnor_6.01417,536,328 - 17,536,436NCBIRnor6.0
Rnor_5.01417,453,706 - 17,453,814UniSTSRnor5.0
RGSC_v3.41417,603,792 - 17,603,900UniSTSRGSC3.4
Celera1415,426,370 - 15,426,478UniSTS
Cytogenetic Map14p22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 44 12
Low 3 34 32 16 19 16 8 8 22 33 23 11 8
Below cutoff 9 25 25 25 2 8 2 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC136013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY383681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000046771   ⟹   ENSRNOP00000045371
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1416,028,363 - 16,061,386 (+)Ensembl
Rnor_6.0 Ensembl1417,534,442 - 17,563,176 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000050038   ⟹   ENSRNOP00000049130
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1416,028,699 - 16,051,371 (+)Ensembl
Rnor_6.0 Ensembl1417,531,398 - 17,554,067 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079304   ⟹   ENSRNOP00000073081
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1416,028,363 - 16,063,252 (+)Ensembl
Rnor_6.0 Ensembl1417,534,412 - 17,565,950 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100781   ⟹   ENSRNOP00000078908
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1416,028,363 - 16,063,252 (+)Ensembl
RefSeq Acc Id: NM_001012035   ⟹   NP_001012035
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,028,699 - 16,051,374 (+)NCBI
Rnor_6.01417,531,398 - 17,554,070 (+)NCBI
Rnor_5.01417,448,431 - 17,483,326 (+)NCBI
RGSC_v3.41417,598,862 - 17,621,559 (+)RGD
Celera1415,421,440 - 15,444,142 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250737   ⟹   XP_006250799
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,028,665 - 16,063,254 (+)NCBI
Rnor_6.01417,531,268 - 17,565,950 (+)NCBI
Rnor_5.01417,448,431 - 17,483,326 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005492936
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,028,657 - 16,063,254 (+)NCBI
RefSeq Acc Id: XR_005492937
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,382 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492938
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,028,656 - 16,063,254 (+)NCBI
RefSeq Acc Id: XR_005492939
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,382 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492940
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,382 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492941
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,382 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492942
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,028,656 - 16,063,254 (+)NCBI
RefSeq Acc Id: XR_005492943
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,382 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492944
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,381 - 16,063,257 (+)NCBI
RefSeq Acc Id: XR_005492945
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21416,027,381 - 16,063,257 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001012035 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250799 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH83590 (Get FASTA)   NCBI Sequence Viewer  
  AAQ96239 (Get FASTA)   NCBI Sequence Viewer  
  EDL88599 (Get FASTA)   NCBI Sequence Viewer  
  Q5XIT0 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001012035   ⟸   NM_001012035
- UniProtKB: Q5XIT0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250799   ⟸   XM_006250737
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K4K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073081   ⟸   ENSRNOT00000079304
RefSeq Acc Id: ENSRNOP00000045371   ⟸   ENSRNOT00000046771
RefSeq Acc Id: ENSRNOP00000049130   ⟸   ENSRNOT00000050038
RefSeq Acc Id: ENSRNOP00000078908   ⟸   ENSRNOT00000100781
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIT0-F1-model_v2 AlphaFold Q5XIT0 1-507 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309625 AgrOrtholog
BioCyc Gene G2FUF-16242 BioCyc
Ensembl Genes ENSRNOG00000002506 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000045371.3 UniProtKB/TrEMBL
  ENSRNOP00000049130 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073081 ENTREZGENE
  ENSRNOP00000073081.2 UniProtKB/TrEMBL
  ENSRNOP00000078908.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046771.5 UniProtKB/TrEMBL
  ENSRNOT00000050038 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079304 ENTREZGENE
  ENSRNOT00000079304.2 UniProtKB/TrEMBL
  ENSRNOT00000100781.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132550 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305242 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94313 IMAGE-MGC_LOAD
NCBI Gene 305242 ENTREZGENE
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdkl2 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K4K8 ENTREZGENE, UniProtKB/TrEMBL
  CDKL2_RAT UniProtKB/Swiss-Prot
  F7F9E5_RAT UniProtKB/TrEMBL
  Q5XIT0 ENTREZGENE
  Q6TXH3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Cdkl2  cyclin dependent kinase like 2  Cdkl2  cyclin-dependent kinase-like 2 (CDC2-related kinase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cdkl2  cyclin-dependent kinase-like 2 (CDC2-related kinase)  Cdkl2_predicted  cyclin-dependent kinase-like 2 (CDC2-related kinase) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cdkl2_predicted  cyclin-dependent kinase-like 2 (CDC2-related kinase) (predicted)      Symbol and Name status set to approved 70820 APPROVED