Septin11 (septin 11) - Rat Genome Database

Name: Septin11
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Septin11 (septin 11) Rattus norvegicus

Analyze

Symbol:

Septin11

Name:

septin 11

RGD ID:

1307405

Description:

Predicted to enable GTPase activity and molecular adaptor activity. Involved in regulation of synapse organization. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic specialization of symmetric synapse. Orthologous to human SEPTIN11 (septin 11); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC305227; Sept11; Sept6; septin 6; septin-11

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SEPTIN11 (septin 11)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Septin11 (septin 11)	HGNC	Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Septin11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SEPTIN11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SEPTIN11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Septin11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SEPTIN11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SEPTIN11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Septin11 (septin 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SEPTIN6 (septin 6)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	SEPTIN11 (septin 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Mus musculus (house mouse):	Septin11 (septin 11)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Drosophila melanogaster (fruit fly):	Sep2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Caenorhabditis elegans (roundworm):	unc-61	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SHS1	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	14,844,759 - 14,990,856 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	14	14,844,580 - 14,990,853 (-)	Ensembl
Rnor_6.0	14	16,369,544 - 16,405,645 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	16,369,544 - 16,452,998 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	16,295,536 - 16,331,637 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	16,465,348 - 16,501,284 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	14	16,464,587 - 16,550,314 (-)	NCBI
Celera	14	14,310,209 - 14,346,008 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive cerebellar ataxia (ISO)

methylmalonic acidemia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

3-chloropropane-1,2-diol (EXP)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

acetamide (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

aristolochic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

Benoxacor (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

bucladesine (ISO)

carbon nanotube (ISO)

chrysene (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

eugenol (ISO)

gentamycin (EXP)

glafenine (EXP)

hyaluronic acid (EXP)

hydrogen peroxide (EXP)

isotretinoin (ISO)

ivermectin (ISO)

mancozeb (ISO)

medroxyprogesterone acetate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

microcystin (EXP)

microcystin RR (ISO)

nickel sulfate (ISO)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (EXP)

sunitinib (ISO)

tamibarotene (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

tetrahydropalmatine (ISO)

tetraphene (ISO)

thioacetamide (EXP)

torcetrapib (ISO)

trichloroethene (EXP)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoskeleton-dependent cytokinesis (IBA)

protein localization (IBA)

regulation of synapse organization (IDA,IMP)

Cellular Component

anchoring junction (IEA)

axon (IEA)

cell division site (IBA)

cytoplasm (IEA)

cytoskeleton (IEA)

dendritic spine (IEA)

GABA-ergic synapse (IDA,IMP)

glutamatergic synapse (IDA)

microtubule cytoskeleton (IBA)

postsynapse (IDA)

postsynaptic specialization of symmetric synapse (IDA)

septin complex (IBA,ISO,ISS)

septin ring (IBA)

stress fiber (ISO)

Molecular Function

GTP binding (IEA)

GTPase activity (IBA)

molecular adaptor activity (IBA)

protein binding (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	Li X, etal., J Biol Chem. 2009 Jun 19;284(25):17253-65. doi: 10.1074/jbc.M109.008870. Epub 2009 Apr 20.
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15485874	PMID:16854843	PMID:17546647	PMID:18809578	PMID:22871113	PMID:23376485	PMID:29476059

Genomics

Comparative Map Data

Septin11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	14	14,844,759 - 14,990,856 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	14	14,844,580 - 14,990,853 (-)	Ensembl
Rnor_6.0	14	16,369,544 - 16,405,645 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	16,369,544 - 16,452,998 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	16,295,536 - 16,331,637 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	16,465,348 - 16,501,284 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	14	16,464,587 - 16,550,314 (-)	NCBI
Celera	14	14,310,209 - 14,346,008 (-)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

SEPTIN11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	76,949,752 - 77,040,154 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	4	76,949,751 - 77,040,384 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	77,870,905 - 77,959,768 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	78,089,919 - 78,178,792 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	4	78,228,073 - 78,316,946	NCBI
Celera	4	75,172,269 - 75,261,155 (+)	NCBI
Cytogenetic Map	4	q21.1	NCBI
HuRef	4	73,622,723 - 73,711,589 (+)	NCBI		HuRef
CHM1_1	4	77,848,139 - 77,937,022 (+)	NCBI		CHM1_1

Septin11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	93,227,445 - 93,329,237 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	5	93,241,296 - 93,324,306 (+)	Ensembl
GRCm38	5	93,090,995 - 93,182,368 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	93,093,437 - 93,176,447 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	93,522,483 - 93,603,984 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	5	94,168,661 - 94,250,162 (+)	NCBI			mm8
Celera	5	91,247,357 - 91,328,543 (+)	NCBI		Celera
Cytogenetic Map	5	E2	NCBI
cM Map	5	47.29	NCBI

Septin11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955433	1,606,261 - 1,691,812 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955433	1,606,246 - 1,691,819 (+)	NCBI	ChiLan1.0	ChiLan1.0

SEPTIN11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	53,004,755 - 53,095,427 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	53,006,294 - 53,095,844 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	47,165,381 - 47,255,954 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

SEPTIN11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	1,553,208 - 1,608,132 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	1,475,748 - 1,607,107 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	40,276,043 - 40,371,637 (-)	NCBI
ROS_Cfam_1.0	32	1,538,003 - 1,640,039 (+)	NCBI
ROS_Cfam_1.0 Ensembl	32	1,539,127 - 1,640,050 (+)	Ensembl
UMICH_Zoey_3.1	32	1,536,272 - 1,629,688 (+)	NCBI
UNSW_CanFamBas_1.0	32	1,492,069 - 1,585,224 (+)	NCBI
UU_Cfam_GSD_1.0	32	38,587,743 - 38,684,577 (-)	NCBI

Septin11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	10,562,850 - 10,699,922 (-)	NCBI
SpeTri2.0	NW_004936676	852,115 - 944,387 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SEPTIN11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	72,543,620 - 72,679,173 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	72,543,641 - 72,679,173 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	76,788,927 - 76,879,982 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SEPTIN11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	25,449,480 - 25,541,029 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	7	25,448,672 - 25,535,055 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666037	3,797,467 - 3,894,729 (+)	NCBI	Vero_WHO_p1.0

Septin11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624757	13,932,153 - 14,039,741 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

AW548875

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	14,909,373 - 14,909,477 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	16,371,189 - 16,371,292	NCBI	Rnor6.0
Rnor_5.0	14	16,297,181 - 16,297,284	UniSTS	Rnor5.0
RGSC_v3.4	14	16,466,993 - 16,467,096	UniSTS	RGSC3.4
Celera	14	14,311,854 - 14,311,957	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH136848

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	14,908,961 - 14,909,164 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	16,370,777 - 16,370,979	NCBI	Rnor6.0
Rnor_5.0	14	16,296,769 - 16,296,971	UniSTS	Rnor5.0
RGSC_v3.4	14	16,466,581 - 16,466,783	UniSTS	RGSC3.4
Celera	14	14,311,442 - 14,311,644	UniSTS
RH 3.4 Map	14	163.6	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH138671

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	14,907,156 - 14,907,333 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	16,368,973 - 16,369,149	NCBI	Rnor6.0
Rnor_5.0	14	16,294,965 - 16,295,141	UniSTS	Rnor5.0
RGSC_v3.4	14	16,464,777 - 16,464,953	UniSTS	RGSC3.4
Celera	14	14,309,638 - 14,309,814	UniSTS
RH 3.4 Map	14	165.2	UniSTS
Cytogenetic Map	14	p22	UniSTS

RH139145

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	14,909,378 - 14,909,545 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	16,371,194 - 16,371,360	NCBI	Rnor6.0
Rnor_5.0	14	16,297,186 - 16,297,352	UniSTS	Rnor5.0
RGSC_v3.4	14	16,466,998 - 16,467,164	UniSTS	RGSC3.4
Celera	14	14,311,859 - 14,312,025	UniSTS
RH 3.4 Map	14	177.4	UniSTS
Cytogenetic Map	14	p22	UniSTS

UniSTS:235223

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	14,910,095 - 14,910,270 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	16,371,911 - 16,372,085	NCBI	Rnor6.0
Rnor_5.0	14	16,297,903 - 16,298,077	UniSTS	Rnor5.0
RGSC_v3.4	14	16,467,715 - 16,467,889	UniSTS	RGSC3.4
Celera	14	14,312,576 - 14,312,750	UniSTS
Cytogenetic Map	14	p22	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	total urine protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat
70204	Niddm20	Non-insulin dependent diabetes mellitus QTL 20	5.1	0.000008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	1217606	16960180	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	3813074	18274691	Rat
2293089	Iddm31	Insulin dependent diabetes mellitus QTL 31	4.7		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	14	3813074	18274691	Rat
1300114	Srn2	Serum renin concentration QTL 2	3.27		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	3813074	21217635	Rat
70195	Mcs8	Mammary carcinoma susceptibility QTL 8	4.28		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	14	3813074	24531477	Rat
1331740	Bw26	Body weight QTL 26	3.028		body mass (VT:0001259)	body weight (CMO:0000012)	14	3813074	30767156	Rat
1581500	Renag1	Renal agenesis QTL 1			kidney development trait (VT:0000527)	percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)	14	8170668	68298175	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8267090	53267090	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8267090	53267090	Rat
731183	Pia20	Pristane induced arthritis QTL 20	3.55		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	9088978	39057237	Rat
2302277	Gluco38	Glucose level QTL 38	5.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	28035204	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
631212	Bw5	Body weight QTL5	5.43		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	11030812	30320092	Rat
1300140	Srn3	Serum renin concentration QTL 3	3.19		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	14	14875168	30883947	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	106
Count of miRNA genes:	80
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000067222
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	37	38	28	19	28	2	5	74	35	34	11	2
Low		6	19	13		13	6	6			7		6
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005492933	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC167769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474060	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU711414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU711415	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU711416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU711417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000067222 ⟹ ENSRNOP00000062626

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	14,907,377 - 14,990,701 (-)	Ensembl
Rnor_6.0 Ensembl	14	16,369,544 - 16,452,890 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000091577 ⟹ ENSRNOP00000069146

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	14,908,882 - 14,990,773 (-)	Ensembl
Rnor_6.0 Ensembl	14	16,371,979 - 16,452,998 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100885 ⟹ ENSRNOP00000090314

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	14,907,350 - 14,990,832 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000103937 ⟹ ENSRNOP00000090630

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	14,915,428 - 14,943,737 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000111632 ⟹ ENSRNOP00000078633

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	14,844,580 - 14,990,853 (-)	Ensembl

RefSeq Acc Id:

NM_001107208 ⟹ NP_001100678

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,350 - 14,990,832 (-)	NCBI
Rnor_6.0	14	16,369,544 - 16,405,645 (-)	NCBI
Rnor_5.0	14	16,295,536 - 16,331,637 (-)	NCBI
RGSC_v3.4	14	16,465,348 - 16,501,284 (-)	RGD
Celera	14	14,310,209 - 14,346,008 (-)	RGD

Sequence:

show sequence

ATGGCCGTGGCGGTGGGGAGACCGAGTAATGAAGAACTGCGAAACTTATCACTTTCTGGCCATG
TTGGATTTGACAGTCTCCCTGACCAGCTGGTCAACAAATCCACTTCTCAAGGATTCTGTTTCAA
CATCCTGTGTGTGGGAGAGACAGGTATTGGCAAATCCACATTGATGGACACTTTATTCAACACC
AAATTTGAAAGTGACCCAGCTACTCACAACGAACCAGGTGTCCGGTTAAAAGCCAGAAGTTACG
AACTGCAGGAAAGCAACGTACGGCTGAAGCTAACCATTGTTGACACAGTGGGATTTGGAGACCA
GATTAATAAAGACGACAGCTATAAGCCCATAGTGGAGTACATTGACGCCCAGTTTGAGGCCTAC
TTGCAAGAGGAATTGAAAATTAAGCGTTCTCTCTTCAACTACCACGACACGAGGATTCACGCCT
GCCTTTACTTTATCGCCCCCACGGGACATTCACTGAAGTCCCTGGACCTGGTCACCATGAAGAA
GCTGGACAGCAAGGTGAACATCATCCCAATCATTGCGAAAGCCGACACCATCGCCAAGAACGAA
TTGCACAAGTTCAAGAGTAAGATCATGAGTGAACTCGTGAGCAACGGAGTCCAGATATATCAGT
TCCCCACCGATGAGGAAACGGTGGCCGAGATTAATGCAACGATGAGTGTCCATCTCCCATTTGC
AGTGGTTGGCAGTACCGAAGAGGTGAAGATTGGCAACAAGATGGCGAAGGCCAGGCAGTACCCT
TGGGGTGTGGTGCAGGTTGAGAACGAAAACCACTGTGATTTTGTGAAGCTGAGGGAGATGCTGA
TCCGAGTGAACATGGAGGACCTGCGAGAGCAGACGCACACTCGCCACTACGAGTTGTATCGGCG
CTGTAAGCTCGAGGAGATGGGCTTCAAGGACACTGACCCTGACAGCAAGCCCTTCAGTCTCCAG
GAGACATATGAAGCAAAGAGGAATGAGTTCCTGGGAGAGCTGCAGAAGAAGGAGGAGGAGATGA
GACAGATGTTTGTCATGAGAGTGAAGGAGAAAGAGGCGGAGCTCAAGGAGGCGGAGAAAGAGCT
TCATGAGAAGTTTGACCTCCTGAAGCGGACTCACCAAGAGGAGAAGAAAAAGGTGGAAGACAAG
AAGAAGGAGCTTGAGGAGGAGGTGAGCAACTTCCAGAAGAAGAAGGCGGCGGCTCAGCTCTTGC
AGTCGCAGGCCCAGCAGTCTGGGGCCCAGCAGACCAAGAAGGACAAGGATAAGAAAAATAGTCC
CTGGCTCTGCACGGAATAAACGATACTCTCAAATCTAACTGGACGTGCTTTCGCCTTTGCATCT
TCTTCTTTATGTAGCCATCACGTTGCCAAGCCCTACTCTCTCTTAATGGACAGCATTAGAAGAG
CGGGAGCTGTCTGTTCACGAGTTGGGGAAGAGTTACCTCATCTCCACCATCGCCTCCCATTCTT
TAAAGTCTGGGTCAAACATTGCACTGCTGTTTGTAATTGTCAATGTCTGTTTACAAACCACCAC
CCTCAGTGGCTACCGAAGTGACTTCAACTACCAAACAAAATAACAATAATATTAAGAGTGGAAT
AGAAAATGTAGGCCCAAACCTGGGGACTTGGGCTGGAATCCTCTTGCTTATTAGCTGCCATTTC
TTGAACCTCCTGATCTAAGACCTTATGGACCGAAGAGAGCATGTACCTCACTTGAGGTTGTCAT
CACCTGCAGGGCAAACATAGCACAAGGTACCCCCTGGTCTCTATCCTATGGGCAAATTTCACCA
ACCCCATCAGGATCTAAAGCTCTTAGCAGGTCATCAGAGCGGGGCAACCCTTGCTGCCTCCTAT
TGGTTTTGTGGGTTGTTCTGGTGTGGGATTTTAGAAAAGGAAAAAAAAAAAAAGAAAGGTATTG
CATGCACAGAGGTGCCTGCAGTTTTCCCTCTGGAACGTCCTATTGATACGGTGTTTTTATTTTT
CAGCTGACCATCTGCCTCTTGAGAGAAAGAAGTGGGCATCC

hide sequence

RefSeq Acc Id:

XM_039091842 ⟹ XP_038947770

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,908,880 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091843 ⟹ XP_038947771

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091844 ⟹ XP_038947772

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,908,880 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091845 ⟹ XP_038947773

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091846 ⟹ XP_038947774

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091847 ⟹ XP_038947775

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,908,880 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091848 ⟹ XP_038947776

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,844 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091849 ⟹ XP_038947777

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,844,759 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XM_039091850 ⟹ XP_038947778

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XR_005492931

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XR_005492932

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,844 - 14,990,856 (-)	NCBI

RefSeq Acc Id:

XR_005492933

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	14,907,328 - 14,990,856 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100678	(Get FASTA)	NCBI Sequence Viewer
	XP_038947770	(Get FASTA)	NCBI Sequence Viewer
	XP_038947771	(Get FASTA)	NCBI Sequence Viewer
	XP_038947772	(Get FASTA)	NCBI Sequence Viewer
	XP_038947773	(Get FASTA)	NCBI Sequence Viewer
	XP_038947774	(Get FASTA)	NCBI Sequence Viewer
	XP_038947775	(Get FASTA)	NCBI Sequence Viewer
	XP_038947776	(Get FASTA)	NCBI Sequence Viewer
	XP_038947777	(Get FASTA)	NCBI Sequence Viewer
	XP_038947778	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI67769	(Get FASTA)	NCBI Sequence Viewer
	ACE00321	(Get FASTA)	NCBI Sequence Viewer
	ACE00322	(Get FASTA)	NCBI Sequence Viewer
	ACE00323	(Get FASTA)	NCBI Sequence Viewer
	ACE00324	(Get FASTA)	NCBI Sequence Viewer
	B3GNI6	(Get FASTA)	NCBI Sequence Viewer
	EDL88655	(Get FASTA)	NCBI Sequence Viewer
	EDL88656	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100678 ⟸ NM_001107208

- UniProtKB:

B3GNI6 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNT
KFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAY
LQEELKIKRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNE
LHKFKSKIMSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMAKARQYP
WGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQ
ETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDK
KKELEEEVSNFQKKKAAAQLLQSQAQQSGAQQTKKDKDKKNSPWLCTE

hide sequence

RefSeq Acc Id:

ENSRNOP00000062626 ⟸ ENSRNOT00000067222

RefSeq Acc Id:

ENSRNOP00000069146 ⟸ ENSRNOT00000091577

RefSeq Acc Id:	XP_038947777 ⟸ XM_039091849
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038947778 ⟸ XM_039091850
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038947774 ⟸ XM_039091846
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038947773 ⟸ XM_039091845
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038947771 ⟸ XM_039091843
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038947776 ⟸ XM_039091848
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038947772 ⟸ XM_039091844
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038947770 ⟸ XM_039091842
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038947775 ⟸ XM_039091847
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSRNOP00000090314 ⟸ ENSRNOT00000100885

RefSeq Acc Id:

ENSRNOP00000078633 ⟸ ENSRNOT00000111632

RefSeq Acc Id:

ENSRNOP00000090630 ⟸ ENSRNOT00000103937

Protein Domains

Septin-type G

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B3GNI6-F1-model_v2	AlphaFold	B3GNI6	1-431	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307405	AgrOrtholog
BioCyc Gene	G2FUF-16283	BioCyc
Ensembl Genes	ENSRNOG00000002182	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000062626	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000069146	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000078633	ENTREZGENE
	ENSRNOP00000090314	ENTREZGENE
Ensembl Transcript	ENSRNOT00000067222	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000091577	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000100885	ENTREZGENE
	ENSRNOT00000111632	ENTREZGENE
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7456582	IMAGE-MGC_LOAD
InterPro	G_SEPTIN_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Septin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:305227	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:187546	IMAGE-MGC_LOAD
NCBI Gene	305227	ENTREZGENE
Pfam	Septin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Septin11	PhenoGen
PIRSF	Septin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_SEPTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JUL7_RAT	UniProtKB/TrEMBL
	B3GNI6	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	B3DMA8	UniProtKB/Swiss-Prot
	B3GNI4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-05	Septin11	septin 11	Sept11	septin 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Sept11	septin 11	Sept6_predicted	septin 6 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Sept6_predicted	septin 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD