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Gene: Prkg2 (protein kinase cGMP-dependent 2) Rattus norvegicus
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Symbol: Prkg2
Name: protein kinase cGMP-dependent 2
Description: Exhibits cGMP-dependent protein kinase activity and identical protein binding activity. Involved in negative regulation of chloride transport; peptidyl-serine autophosphorylation; and protein localization to plasma membrane. Localizes to the nuclear membrane. Orthologous to human PRKG2 (protein kinase cGMP-dependent 2); PARTICIPATES IN long term depression; INTERACTS WITH 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CGK 2; cGK2; cGKII; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; GDPKII; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; type II cGMP-dependent protein kinase
Orthologs:
Homo sapiens (human) : PRKG2 (protein kinase cGMP-dependent 2)  HGNC  Alliance
Mus musculus (house mouse) : Prkg2 (protein kinase, cGMP-dependent, type II)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkg2 (protein kinase cGMP-dependent 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKG2 (protein kinase cGMP-dependent 2)
Canis lupus familiaris (dog) : PRKG2 (protein kinase cGMP-dependent 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkg2 (protein kinase cGMP-dependent 2)
Sus scrofa (pig) : PRKG2 (protein kinase cGMP-dependent 2)
more info ...
Is Marker For: Strains:   KMI/Tky  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01412,217,121 - 12,313,616 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1412,218,553 - 12,315,229 (+)Ensembl
Rnor_5.01412,159,378 - 12,255,994 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41411,888,101 - 12,005,547 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11411,888,100 - 12,005,547 (+)NCBI
Celera1410,666,687 - 10,755,836 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkg2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3401
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.