(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AFP mRNA] CTD PMID:31150632 (+)-taxifolin affects binding EXP 6480464 taxifolin binds to AFP protein CTD PMID:23013281 , PMID:25349334 (S)-naringenin affects binding EXP 6480464 naringenin binds to AFP protein CTD PMID:23013281 , PMID:25349334 1,1-dichloroethene increases expression ISO RGD:10116 6480464 vinylidene chloride results in increased expression of AFP mRNA CTD PMID:26682919 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of AFP mRNA CTD PMID:17108234 17alpha-ethynylestradiol affects binding EXP 6480464 Ethinyl Estradiol binds to AFP protein CTD PMID:23013281 , PMID:25349334 17beta-estradiol multiple interactions ISO RGD:736278 6480464 [Estradiol co-treated with Progesterone] results in increased expression of AFP protein CTD PMID:18497072 17beta-estradiol affects binding EXP 6480464 Estradiol binds to AFP protein CTD PMID:23013281 more ... 17beta-estradiol increases response to substance ISO RGD:10116 6480464 AFP protein results in increased susceptibility to Estradiol CTD PMID:22720075 17beta-estradiol multiple interactions EXP 6480464 Diethylstilbestrol inhibits the reaction [Estradiol binds to AFP protein] CTD PMID:9748407 1H-1,2,4-triazole multiple interactions EXP 6480464 1 more ... CTD PMID:28693887 2,2'-Dihydroxy-4-methoxybenzophenone affects binding EXP 6480464 dioxybenzone binds to AFP protein CTD PMID:23013281 , PMID:25349334 2,3,4,5-Tetrachloro-4'-biphenylol affects binding EXP 6480464 4-hydroxy-2' more ... CTD PMID:23013281 , PMID:25349334 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736278 6480464 Tetrachlorodibenzodioxin results in decreased expression of AFP mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10116 6480464 Tetrachlorodibenzodioxin affects the expression of AFP mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AFP mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AFP mRNA] CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AFP mRNA CTD PMID:15644576 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10116 6480464 Tetrachlorodibenzodioxin results in increased expression of AFP mRNA, Tetrachlorodibenzodioxin results in increased expression of AFP protein CTD PMID:19933214 , PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736278 6480464 Tetrachlorodibenzodioxin results in increased expression of AFP mRNA, Tetrachlorodibenzodioxin results in increased expression of AFP protein CTD PMID:16083274 2,4-diaminotoluene increases expression ISO RGD:10116 6480464 2, 4-diaminotoluene results in increased expression of AFP mRNA CTD PMID:20713471 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of AFP mRNA CTD PMID:21346803 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of AFP protein, [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of AFP protein CTD PMID:11813887 , PMID:6187438 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of AFP mRNA, 2-Acetylaminofluorene results in increased expression of AFP protein CTD PMID:11350689 more ... 2-amino-2-deoxy-D-galactopyranose increases expression EXP 6480464 Galactosamine results in increased expression of AFP protein CTD PMID:16965562 , PMID:61145 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:10116 6480464 Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 2-nitropropane multiple interactions EXP 6480464 diphenyldiselenide inhibits the reaction [2-nitropropane results in increased expression of AFP protein] CTD PMID:15804453 2-nitropropane increases expression EXP 6480464 2-nitropropane results in increased expression of AFP protein CTD PMID:15804453 2-sec-butylphenol affects binding EXP 6480464 2-sec-butylphenol binds to AFP protein CTD PMID:23013281 , PMID:25349334 3'-hydroxyflavanone affects binding EXP 6480464 3-hydroxyflavanone binds to AFP protein CTD PMID:23013281 , PMID:25349334 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 3,5,6-trichloro-2-pyridinol increases expression ISO RGD:10116 6480464 3 more ... CTD PMID:23220036 3,5,6-trichloro-2-pyridinol affects expression ISO RGD:10116 6480464 3 more ... CTD PMID:25137620 3,5,6-trichloropyridine-2-one increases expression ISO RGD:10116 6480464 3 more ... CTD PMID:23220036 3,5,6-trichloropyridine-2-one affects expression ISO RGD:10116 6480464 3 more ... CTD PMID:25137620 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO RGD:10116 6480464 Dicarbethoxydihydrocollidine results in increased expression of AFP mRNA CTD PMID:18098314 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO RGD:10116 6480464 S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of AFP mRNA] CTD PMID:18098314 4'-hydroxychalcone affects binding EXP 6480464 4'-hydroxychalcone binds to AFP protein CTD PMID:23013281 , PMID:25349334 4'-hydroxyflavanone affects binding EXP 6480464 4'-hydroxyflavanone binds to AFP protein CTD PMID:23013281 , PMID:25349334 4,4'-diaminodiphenylmethane affects expression EXP 6480464 4, 4'-diaminodiphenylmethane affects the expression of AFP mRNA CTD PMID:9327722 4,4'-sulfonyldiphenol affects expression ISO RGD:10116 6480464 bis(4-hydroxyphenyl)sulfone affects the expression of AFP mRNA CTD PMID:30951980 4-hydroxychalcone affects binding EXP 6480464 4-hydroxychalcone binds to AFP protein CTD PMID:23013281 , PMID:25349334 4-nonylphenol affects binding EXP 6480464 4-nonylphenol binds to AFP protein CTD PMID:23013281 , PMID:25349334 4-octylphenol affects binding EXP 6480464 4-octylphenol binds to AFP protein CTD PMID:23013281 , PMID:25349334 5-azacytidine increases expression ISO RGD:736278 6480464 Azacitidine results in increased expression of AFP mRNA CTD PMID:27590069 5-fluorouracil increases expression ISO RGD:10116 6480464 Fluorouracil results in increased expression of AFP protein CTD PMID:21296659 5-fluorouracil decreases expression ISO RGD:10116 6480464 Fluorouracil results in decreased expression of AFP, Fluorouracil results in decreased expression of AFP mRNA CTD PMID:20448262 , PMID:26272751 7-hydroxyflavanone affects binding EXP 6480464 7-hydroxyflavanone binds to AFP protein CTD PMID:23013281 , PMID:25349334 acetic acid decreases expression ISO RGD:10116 6480464 Acetic Acid results in decreased expression of AFP protein CTD PMID:21296659 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of AFP mRNA, Aflatoxin B1 results in increased expression of AFP protein CTD PMID:11133813 more ... aflatoxin B1 increases expression ISO RGD:736278 6480464 Aflatoxin B1 results in increased expression of AFP mRNA CTD PMID:20036727 , PMID:27153756 aflatoxin B1 decreases methylation ISO RGD:736278 6480464 Aflatoxin B1 results in decreased methylation of AFP gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:736278 6480464 Aflatoxin B1 results in decreased expression of AFP mRNA CTD PMID:20036727 aflatoxin B1 increases expression ISO RGD:10116 6480464 Aflatoxin B1 results in increased expression of AFP mRNA CTD PMID:19770486 aflatoxin B1 multiple interactions EXP 6480464 ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 aldehydo-D-glucosamine increases expression ISO RGD:10116 6480464 Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 aldehydo-D-glucose increases expression ISO RGD:10116 6480464 Glucose results in increased expression of AFP mRNA CTD PMID:17178593 all-trans-retinoic acid affects expression ISO RGD:10116 6480464 Tretinoin affects the expression of AFP mRNA CTD PMID:25137620 all-trans-retinoic acid affects expression ISO RGD:736278 6480464 Tretinoin affects the expression of AFP mRNA CTD PMID:31600526 all-trans-retinoic acid increases expression ISO RGD:10116 6480464 Tretinoin results in increased expression of AFP mRNA CTD PMID:16619266 , PMID:26272751 all-trans-retinoic acid increases expression ISO RGD:736278 6480464 Tretinoin results in increased expression of AFP mRNA CTD PMID:21934132 all-trans-retinol increases expression EXP 6480464 Vitamin A deficiency results in increased expression of AFP mRNA CTD PMID:7519440 allyl alcohol increases expression ISO RGD:10116 6480464 allyl alcohol results in increased expression of AFP protein CTD PMID:70250 allyl alcohol increases expression EXP 6480464 allyl alcohol results in increased expression of AFP protein CTD PMID:61145 alpha-Zearalanol affects binding EXP 6480464 Zeranol binds to AFP protein CTD PMID:25349334 amiodarone increases expression ISO RGD:10116 6480464 Amiodarone results in increased expression of AFP mRNA CTD PMID:24489787 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AFP mRNA CTD PMID:16483693 apigenin affects binding EXP 6480464 Apigenin binds to AFP protein CTD PMID:23013281 , PMID:25349334 arsenite(3-) increases expression ISO RGD:10116 6480464 arsenite results in increased expression of AFP mRNA CTD PMID:15345372 , PMID:18991936 arsenous acid increases expression ISO RGD:10116 6480464 Arsenic Trioxide results in increased expression of AFP mRNA CTD PMID:29767511 arsenous acid decreases expression ISO RGD:736278 6480464 Arsenic Trioxide results in decreased expression of AFP mRNA, Arsenic Trioxide results in decreased expression of AFP protein CTD PMID:23382965 Azaspiracid decreases expression ISO RGD:736278 6480464 azaspiracid results in decreased expression of AFP mRNA CTD PMID:28939011 baicalein affects binding EXP 6480464 baicalein binds to AFP protein CTD PMID:23013281 , PMID:25349334 belinostat decreases expression ISO RGD:736278 6480464 belinostat results in decreased expression of AFP mRNA CTD PMID:26272509 benzo[a]pyrene increases expression ISO RGD:736278 6480464 Benzo(a)pyrene results in increased expression of AFP mRNA CTD PMID:20106945 benzo[a]pyrene decreases methylation ISO RGD:736278 6480464 Benzo(a)pyrene results in decreased methylation of AFP promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:10116 6480464 Benzo(a)pyrene results in increased expression of AFP mRNA CTD PMID:19770486 more ... benzo[a]pyrene diol epoxide I increases expression ISO RGD:736278 6480464 7 more ... CTD PMID:26238291 Benzyl parahydroxybenzoate affects binding EXP 6480464 benzylparaben binds to AFP protein CTD PMID:23013281 , PMID:25349334 benzylpenicillin affects expression ISO RGD:10116 6480464 Penicillin G affects the expression of AFP mRNA CTD PMID:25137620 benzylpenicillin decreases expression ISO RGD:736278 6480464 Penicillin G results in decreased expression of AFP mRNA CTD PMID:24737281 benzylpenicillin decreases expression ISO RGD:10116 6480464 Penicillin G results in decreased expression of AFP mRNA CTD PMID:26272751 beta-D-glucosamine increases expression ISO RGD:10116 6480464 Glucosamine results in increased expression of AFP mRNA CTD PMID:17178593 beta-Zearalanol affects binding EXP 6480464 taleranol binds to AFP protein CTD PMID:23013281 , PMID:25349334 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10116 6480464 Diethylhexyl Phthalate results in increased expression of AFP mRNA CTD PMID:20307648 bisphenol A affects expression ISO RGD:10116 6480464 bisphenol A affects the expression of AFP mRNA CTD PMID:14967926 , PMID:30951980 bisphenol A affects expression ISO RGD:736278 6480464 bisphenol A affects the expression of AFP mRNA CTD PMID:30903817 bisphenol A increases expression ISO RGD:736278 6480464 bisphenol A results in increased expression of AFP mRNA CTD PMID:27271280 bisphenol A multiple interactions ISO RGD:736278 6480464 IGF1 protein affects the reaction [bisphenol A results in increased expression of AFP mRNA] CTD PMID:27271280 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AFP mRNA CTD PMID:25181051 bisphenol A increases expression ISO RGD:10116 6480464 bisphenol A results in increased expression of AFP protein CTD PMID:26146954 bisphenol F affects expression ISO RGD:10116 6480464 bisphenol F affects the expression of AFP mRNA CTD PMID:30951980 bromochloroacetic acid decreases expression ISO RGD:10116 6480464 bromochloroacetic acid results in decreased expression of AFP protein CTD PMID:21296659 brucine multiple interactions EXP 6480464 brucine inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:24060683 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of AFP promoter CTD PMID:22457795 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AFP mRNA CTD PMID:25993096 carbon nanotube decreases expression ISO RGD:10116 6480464 Nanotubes, Carbon analog results in decreased expression of AFP mRNA, Nanotubes, Carbon results in decreased expression of AFP mRNA CTD PMID:25620056 carbon nanotube increases expression ISO RGD:10116 6480464 Nanotubes, Carbon analog results in increased expression of AFP mRNA, Nanotubes, Carbon results in increased expression of AFP mRNA CTD PMID:25554681 carfilzomib multiple interactions EXP 6480464 carfilzomib inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:24632418 chalcone affects binding EXP 6480464 Chalcone binds to AFP protein CTD PMID:23013281 , PMID:25349334 CHIR 99021 increases expression ISO RGD:736278 6480464 Chir 99021 results in increased expression of AFP mRNA CTD PMID:31711903 chloroprene increases expression ISO RGD:10116 6480464 Chloroprene results in increased expression of AFP mRNA CTD PMID:23125180 chlorpromazine decreases expression ISO RGD:736278 6480464 Chlorpromazine analog results in decreased expression of AFP mRNA CTD PMID:15924885 chlorpyrifos increases expression ISO RGD:10116 6480464 Chlorpyrifos results in increased expression of AFP mRNA CTD PMID:25137620 choline multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Choline deficiency] results in increased expression of AFP protein, [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of AFP protein CTD PMID:19566968 , PMID:6187438 choline multiple interactions ISO RGD:10116 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AFP mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AFP mRNA CTD PMID:20938992 , PMID:29127188 Chorionic gonadotropin increases expression ISO RGD:736278 6480464 Chorionic Gonadotropin results in increased expression of AFP protein CTD PMID:18497072 chrysin affects binding EXP 6480464 chrysin binds to AFP protein CTD PMID:23013281 , PMID:25349334 citral multiple interactions EXP 6480464 citral inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:32302048 clofibrate decreases expression ISO RGD:10116 6480464 Clofibrate results in decreased expression of AFP mRNA CTD PMID:17585979 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of AFP mRNA CTD PMID:24386269 cocaine increases expression EXP 6480464 Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 copper atom multiple interactions ISO RGD:736278 6480464 [NSC 689534 binds to Copper] which results in increased expression of AFP mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:736278 6480464 [NSC 689534 binds to Copper] which results in increased expression of AFP mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:736278 6480464 Copper Sulfate results in decreased expression of AFP mRNA CTD PMID:19549813 coumestrol affects binding EXP 6480464 Coumestrol binds to AFP protein CTD PMID:23013281 , PMID:25349334 cyclophosphamide affects expression ISO RGD:10116 6480464 Cyclophosphamide affects the expression of AFP protein CTD PMID:6177358 cyclosporin A increases expression ISO RGD:736278 6480464 Cyclosporine results in increased expression of AFP mRNA CTD PMID:20106945 cyclosporin A decreases expression ISO RGD:736278 6480464 Cyclosporine results in decreased expression of AFP mRNA CTD PMID:25562108 , PMID:27989131 cylindrospermopsin decreases expression ISO RGD:736278 6480464 cylindrospermopsin results in decreased expression of AFP mRNA CTD PMID:30500929 D-glucose increases expression ISO RGD:10116 6480464 Glucose results in increased expression of AFP mRNA CTD PMID:17178593 diarsenic trioxide increases expression ISO RGD:10116 6480464 Arsenic Trioxide results in increased expression of AFP mRNA CTD PMID:29767511 diarsenic trioxide decreases expression ISO RGD:736278 6480464 Arsenic Trioxide results in decreased expression of AFP mRNA, Arsenic Trioxide results in decreased expression of AFP protein CTD PMID:23382965 dicrotophos decreases expression ISO RGD:736278 6480464 dicrotophos results in decreased expression of AFP mRNA CTD PMID:28302478 dienestrol affects binding EXP 6480464 Dienestrol binds to AFP protein CTD PMID:23013281 , PMID:25349334 diethyl maleate increases expression ISO RGD:10116 6480464 diethyl maleate results in increased expression of AFP mRNA CTD PMID:25270620 diethyl phthalate affects binding EXP 6480464 diethyl phthalate binds to AFP protein CTD PMID:23013281 , PMID:25349334 diethylstilbestrol multiple interactions ISO RGD:10116 6480464 [Diethylstilbestrol co-treated with sodium arsenite] results in increased expression of AFP mRNA CTD PMID:19665456 diethylstilbestrol affects binding EXP 6480464 Diethylstilbestrol binds to AFP protein CTD PMID:23013281 more ... diethylstilbestrol multiple interactions EXP 6480464 Diethylstilbestrol inhibits the reaction [Estradiol binds to AFP protein] CTD PMID:9748407 Dimethyl phthalate affects binding EXP 6480464 dimethyl phthalate binds to AFP protein CTD PMID:23013281 , PMID:25349334 dimethylarsinic acid increases expression ISO RGD:10116 6480464 Cacodylic Acid results in increased expression of AFP mRNA CTD PMID:15345372 dorsomorphin multiple interactions ISO RGD:736278 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions EXP 6480464 chloroquine diphosphate promotes the reaction [Doxorubicin inhibits the reaction [Thioacetamide results in increased expression of AFP protein]] more ... CTD PMID:29133031 doxorubicin decreases expression ISO RGD:736278 6480464 Doxorubicin results in decreased expression of AFP mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO RGD:10116 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein] CTD PMID:21251210 doxorubicin decreases expression ISO RGD:10116 6480464 Doxorubicin results in decreased expression of AFP protein CTD PMID:21251210 ebselen multiple interactions EXP 6480464 ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 equol affects binding EXP 6480464 Equol binds to AFP protein CTD PMID:23013281 , PMID:25349334 estra-1,3,5(10)-trien-3-ol affects binding EXP 6480464 17-desoxyestradiol binds to AFP protein CTD PMID:23013281 , PMID:25349334 estriol increases expression ISO RGD:736278 6480464 Estriol results in increased expression of AFP protein CTD PMID:18497072 estriol affects binding EXP 6480464 Estriol binds to AFP protein CTD PMID:23013281 , PMID:25349334 estriol increases expression ISO RGD:10116 6480464 Estriol results in increased expression of AFP protein CTD PMID:2470397 estrone affects binding EXP 6480464 Estrone binds to AFP protein CTD PMID:23013281 , PMID:25349334 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of AFP protein CTD PMID:24646710 fisetin affects binding EXP 6480464 fisetin binds to AFP protein CTD PMID:23013281 , PMID:25349334 flavanone affects binding EXP 6480464 flavanone binds to AFP protein CTD PMID:23013281 , PMID:25349334 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of AFP mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:10116 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AFP mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AFP mRNA CTD PMID:20938992 , PMID:29127188 folic acid multiple interactions EXP 6480464 [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of AFP protein CTD PMID:19566968 formaldehyde increases expression ISO RGD:736278 6480464 Formaldehyde results in increased expression of AFP protein CTD PMID:16966304 fosinopril multiple interactions ISO RGD:10116 6480464 Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 furan increases expression ISO RGD:10116 6480464 furan results in increased expression of AFP mRNA CTD PMID:24183702 furan increases expression EXP 6480464 furan results in increased expression of AFP mRNA CTD PMID:25539665 , PMID:26194646 gemcitabine decreases expression ISO RGD:736278 6480464 gemcitabine results in decreased expression of AFP protein CTD PMID:20531411 geranial multiple interactions EXP 6480464 citral inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:32302048 glucose increases expression ISO RGD:10116 6480464 Glucose results in increased expression of AFP mRNA CTD PMID:17178593 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein], Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:28935427 , PMID:30779474 hexestrol affects binding EXP 6480464 Hexestrol binds to AFP protein CTD PMID:23013281 hypochlorous acid increases expression ISO RGD:10116 6480464 Hypochlorous Acid results in increased expression of AFP mRNA CTD PMID:19376150 isoliquiritigenin affects binding EXP 6480464 isoliquiritigenin binds to AFP protein CTD PMID:23013281 isoniazide decreases expression ISO RGD:736278 6480464 Isoniazid results in decreased expression of AFP mRNA CTD PMID:30008028 kaempferol affects binding EXP 6480464 kaempferol binds to AFP protein CTD PMID:23013281 , PMID:25349334 kaempferol decreases expression ISO RGD:10116 6480464 kaempferol results in decreased expression of AFP protein CTD PMID:26683311 ketamine increases expression EXP 6480464 Ketamine results in increased expression of AFP mRNA CTD PMID:20080153 L-ethionine increases expression EXP 6480464 Ethionine results in increased expression of AFP protein CTD PMID:61145 L-methionine multiple interactions ISO RGD:10116 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AFP mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AFP mRNA CTD PMID:20938992 , PMID:29127188 L-methionine multiple interactions EXP 6480464 [Folic Acid deficiency co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of AFP protein CTD PMID:19566968 levofloxacin decreases expression EXP 6480464 Levofloxacin results in decreased expression of AFP mRNA CTD PMID:24136188 lipopolysaccharide increases expression ISO RGD:10116 6480464 Lipopolysaccharides results in increased expression of AFP mRNA CTD PMID:27339419 losartan multiple interactions ISO RGD:10116 6480464 Losartan inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 manganese atom decreases expression EXP 6480464 Manganese results in decreased expression of AFP mRNA CTD PMID:26745496 manganese(0) decreases expression EXP 6480464 Manganese results in decreased expression of AFP mRNA CTD PMID:26745496 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 masoprocol affects binding EXP 6480464 Masoprocol binds to AFP protein CTD PMID:23013281 , PMID:25349334 mercury dibromide multiple interactions ISO RGD:736278 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AFP mRNA CTD PMID:27188386 mestranol affects binding EXP 6480464 Mestranol binds to AFP protein CTD PMID:23013281 , PMID:25349334 methimazole increases expression ISO RGD:10116 6480464 Methimazole results in increased expression of AFP mRNA CTD PMID:29990518 methimazole increases expression ISO RGD:736278 6480464 Methimazole results in increased expression of AFP mRNA CTD PMID:29990518 methimazole multiple interactions ISO RGD:736278 6480464 Methimazole inhibits the reaction [IGF1 protein results in decreased expression of AFP mRNA] CTD PMID:29990518 methylarsonic acid increases expression ISO RGD:10116 6480464 monomethylarsonic acid results in increased expression of AFP mRNA CTD PMID:15345372 methylmercury chloride decreases expression ISO RGD:736278 6480464 methylmercuric chloride results in decreased expression of AFP mRNA CTD PMID:23179753 , PMID:27188386 monobenzone affects binding EXP 6480464 monobenzone binds to AFP protein CTD PMID:23013281 myricetin affects binding EXP 6480464 myricetin binds to AFP protein CTD PMID:23013281 , PMID:25349334 N,N'-diphenyl-1,4-phenylenediamine multiple interactions EXP 6480464 N, N'-diphenyl-4-phenylenediamine inhibits the reaction [Carbon Tetrachloride results in increased expression of AFP protein] CTD PMID:61145 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of AFP mRNA CTD PMID:28801915 N-methyl-N-nitrosourea decreases response to substance EXP 6480464 AFP protein modified form results in decreased susceptibility to Methylnitrosourea CTD PMID:16322315 N-nitrosodiethylamine multiple interactions EXP 6480464 1 more ... CTD PMID:19394651 more ... N-nitrosodiethylamine increases expression ISO RGD:10116 6480464 Diethylnitrosamine results in increased expression of AFP mRNA, Diethylnitrosamine results in increased expression of AFP protein CTD PMID:15766596 more ... N-nitrosodiethylamine multiple interactions ISO RGD:10116 6480464 [1 more ... CTD PMID:21391223 more ... N-nitrosodiethylamine affects expression EXP 6480464 Diethylnitrosamine affects the expression of AFP mRNA CTD PMID:19822196 N-nitrosodiethylamine decreases expression ISO RGD:736278 6480464 Diethylnitrosamine results in decreased expression of AFP mRNA CTD PMID:21527772 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of AFP mRNA, Diethylnitrosamine results in increased expression of AFP protein CTD PMID:11818250 more ... N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of AFP mRNA CTD PMID:17072980 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of AFP protein CTD PMID:16965562 nickel atom decreases expression ISO RGD:10116 6480464 Nickel analog results in decreased expression of AFP protein CTD PMID:25144474 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of AFP mRNA CTD PMID:22110744 ochratoxin A increases expression ISO RGD:736278 6480464 ochratoxin A results in increased expression of AFP mRNA CTD PMID:30008028 ozone multiple interactions ISO RGD:10116 6480464 TTPA protein affects the reaction [Ozone results in increased expression of AFP mRNA] CTD PMID:19555225 panaxydol decreases secretion ISO RGD:736278 6480464 panaxydol results in decreased secretion of AFP protein CTD PMID:19450571 paracetamol increases expression ISO RGD:10116 6480464 Acetaminophen results in increased expression of AFP mRNA, Acetaminophen results in increased expression of AFP protein CTD PMID:29246445 , PMID:70250 paracetamol multiple interactions ISO RGD:10116 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of AFP mRNA] CTD PMID:29246445 paracetamol decreases expression ISO RGD:736278 6480464 Acetaminophen results in decreased expression of AFP mRNA, Acetaminophen results in decreased expression of AFP protein CTD PMID:22230336 , PMID:30008028 paracetamol affects expression ISO RGD:10116 6480464 Acetaminophen affects the expression of AFP mRNA CTD PMID:17562736 perindopril multiple interactions ISO RGD:10116 6480464 Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 phenobarbital multiple interactions ISO RGD:10116 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP mRNA, NR1I3 protein affects the reaction [Phenobarbital results in increased expression of AFP mRNA] CTD PMID:19482888 , PMID:24535843 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP protein more ... CTD PMID:28414157 phenobarbital affects expression ISO RGD:10116 6480464 Phenobarbital affects the expression of AFP mRNA CTD PMID:23091169 phenobarbital increases expression ISO RGD:10116 6480464 Phenobarbital results in increased expression of AFP mRNA CTD PMID:19482888 phenol increases expression ISO RGD:736278 6480464 Phenol results in increased expression of AFP protein CTD PMID:16966304 phenylmercury acetate increases expression ISO RGD:736278 6480464 Phenylmercuric Acetate results in increased expression of AFP mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736278 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AFP mRNA CTD PMID:27188386 phenytoin decreases expression ISO RGD:736278 6480464 Phenytoin results in decreased expression of AFP mRNA CTD PMID:14741686 phenytoin decreases expression ISO RGD:10116 6480464 Phenytoin results in decreased expression of AFP mRNA CTD PMID:26272751 phloretin affects binding EXP 6480464 Phloretin binds to AFP protein CTD PMID:23013281 , PMID:25349334 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10116 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP mRNA, [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP protein CTD PMID:16368122 pirinixic acid multiple interactions ISO RGD:736278 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AFP mRNA CTD PMID:19710929 pirinixic acid affects expression ISO RGD:10116 6480464 pirinixic acid affects the expression of AFP mRNA CTD PMID:23811191 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:10116 6480464 Pregnenolone Carbonitrile results in decreased expression of AFP mRNA CTD PMID:27413110 , PMID:28903501 progesterone multiple interactions ISO RGD:736278 6480464 [Estradiol co-treated with Progesterone] results in increased expression of AFP protein CTD PMID:18497072 progesterone increases response to substance ISO RGD:10116 6480464 AFP protein results in increased susceptibility to Progesterone CTD PMID:22720075 quercetin affects binding EXP 6480464 Quercetin binds to AFP protein CTD PMID:23013281 , PMID:25349334 rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29458170 S-adenosyl-L-methioninate decreases expression ISO RGD:10116 6480464 S-Adenosylmethionine results in decreased expression of AFP mRNA CTD PMID:18098314 S-adenosyl-L-methioninate multiple interactions ISO RGD:10116 6480464 S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of AFP mRNA] CTD PMID:18098314 S-adenosyl-L-methionine multiple interactions ISO RGD:10116 6480464 S-Adenosylmethionine inhibits the reaction [Dicarbethoxydihydrocollidine results in increased expression of AFP mRNA] CTD PMID:18098314 S-adenosyl-L-methionine decreases expression ISO RGD:10116 6480464 S-Adenosylmethionine results in decreased expression of AFP mRNA CTD PMID:18098314 saccharin increases expression ISO RGD:10116 6480464 Saccharin results in increased expression of AFP mRNA CTD PMID:26272751 SB 431542 multiple interactions ISO RGD:736278 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver atom increases expression ISO RGD:10116 6480464 Silver results in increased expression of AFP mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:10116 6480464 Silver results in increased expression of AFP mRNA CTD PMID:27131904 simvastatin increases expression ISO RGD:736278 6480464 Simvastatin results in increased expression of AFP mRNA CTD PMID:10365819 sodium arsenite increases expression ISO RGD:10116 6480464 sodium arsenite results in increased expression of AFP mRNA, sodium arsenite results in increased expression of AFP protein CTD PMID:14691202 more ... sodium arsenite multiple interactions ISO RGD:10116 6480464 [Diethylstilbestrol co-treated with sodium arsenite] results in increased expression of AFP mRNA more ... CTD PMID:16368122 , PMID:19665456 sodium arsenite affects expression ISO RGD:10116 6480464 sodium arsenite affects the expression of AFP mRNA CTD PMID:16507464 sodium arsenite decreases expression ISO RGD:736278 6480464 sodium arsenite results in decreased expression of AFP mRNA CTD PMID:19615344 sodium arsenite multiple interactions ISO RGD:736278 6480464 monoisoamyl-2, 3-dimercaptosuccinate inhibits the reaction [sodium arsenite results in decreased expression of AFP mRNA] CTD PMID:19615344 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AFP mRNA, sodium arsenite results in increased expression of AFP protein CTD PMID:16876216 sodium nitrate multiple interactions ISO RGD:10116 6480464 sodium nitrate inhibits the reaction [Doxorubicin results in decreased expression of AFP protein] CTD PMID:21251210 sorafenib multiple interactions ISO RGD:10116 6480464 Sorafenib inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:29859236 streptozocin multiple interactions ISO RGD:10116 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA CTD PMID:29127188 succimer multiple interactions ISO RGD:10116 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of AFP mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of AFP mRNA CTD PMID:21641980 , PMID:26378955 tamoxifen increases expression ISO RGD:10116 6480464 Tamoxifen results in increased expression of AFP mRNA CTD PMID:25123088 tamoxifen affects expression ISO RGD:10116 6480464 Tamoxifen affects the expression of AFP mRNA CTD PMID:20937368 tetrachloromethane increases expression ISO RGD:10116 6480464 Carbon Tetrachloride results in increased expression of AFP mRNA, Carbon Tetrachloride results in increased expression of AFP protein CTD PMID:16965562 more ... tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of AFP mRNA CTD PMID:31150632 tetrachloromethane multiple interactions ISO RGD:10116 6480464 Diethylnitrosamine promotes the reaction [Carbon Tetrachloride results in increased expression of AFP mRNA] CTD PMID:23288052 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of AFP protein CTD PMID:16965562 , PMID:61145 tetrachloromethane multiple interactions EXP 6480464 1 more ... CTD PMID:11813887 more ... thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of AFP protein CTD PMID:29133031 , PMID:61145 thioacetamide multiple interactions EXP 6480464 chloroquine diphosphate inhibits the reaction [Thioacetamide results in increased expression of AFP protein] more ... CTD PMID:29133031 thymoquinone multiple interactions EXP 6480464 thymoquinone inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein], thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:24012840 , PMID:29923357 titanium dioxide increases expression ISO RGD:10116 6480464 titanium dioxide results in increased expression of AFP mRNA CTD PMID:23557971 trans-chalcone affects binding EXP 6480464 Chalcone binds to AFP protein CTD PMID:23013281 , PMID:25349334 tributylstannane increases expression ISO RGD:10116 6480464 tributyltin results in increased expression of AFP mRNA CTD PMID:31939706 triclosan decreases expression ISO RGD:736278 6480464 Triclosan results in decreased expression of AFP mRNA CTD PMID:30510588 tris(2-butoxyethyl) phosphate affects expression ISO RGD:736278 6480464 tris(2-butoxyethyl) phosphate affects the expression of AFP mRNA CTD PMID:29024780 urea increases expression ISO RGD:736278 6480464 Urea results in increased expression of AFP protein CTD PMID:16966304 valproic acid increases expression ISO RGD:10116 6480464 Valproic Acid results in increased expression of AFP mRNA CTD PMID:25137620 valproic acid decreases expression ISO RGD:736278 6480464 Valproic Acid results in decreased expression of AFP mRNA CTD PMID:23179753 , PMID:27188386 valproic acid decreases expression ISO RGD:10116 6480464 Valproic Acid results in decreased expression of AFP mRNA CTD PMID:26272751 valproic acid increases expression ISO RGD:736278 6480464 Valproic Acid results in increased expression of AFP mRNA CTD PMID:25084468 , PMID:28001369 zinc dichloride decreases expression ISO RGD:736278 6480464 zinc chloride results in decreased expression of AFP mRNA CTD PMID:18947441 zoledronic acid increases expression ISO RGD:736278 6480464 zoledronic acid results in increased expression of AFP protein CTD PMID:28871336
Gene-Chemical Interaction Annotations
