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Gene: Afp (alpha-fetoprotein) Rattus norvegicus
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Symbol: Afp
Name: alpha-fetoprotein
Description: Predicted to have metal ion binding activity. Involved in animal organ development and response to organic substance. Localizes to the cytoplasm and extracellular space. Orthologous to human AFP (alpha fetoprotein); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH (+)-schisandrin B; (+)-taxifolin; (S)-naringenin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1-fetoprotein; alpha-fetoglobulin; chloride intracellular channel 6
Orthologs:
Homo sapiens (human) : AFP (alpha fetoprotein)  HGNC  Alliance
Mus musculus (house mouse) : Afp (alpha fetoprotein)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AFP (alpha fetoprotein)
Canis lupus familiaris (dog) : AFP (alpha fetoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Afp (alpha fetoprotein)
Sus scrofa (pig) : AFP (alpha fetoprotein)
more info ...
Is Marker For: QTLs:   Scl11  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01419,141,755 - 19,159,919 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01419,049,096 - 19,067,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41419,092,563 - 19,110,728 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11419,092,562 - 19,110,728 (-)NCBI
Celera1416,939,827 - 16,957,879 (-)NCBICelera
Cytogenetic Map14p22NCBI
RH 3.4 Map14214.49RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Afp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2065
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.