Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2065
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Afp
Name: alpha-fetoprotein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Afpdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AFP mRNAPMID:25181051
Afpincreases expressionEXP 6480464CTDbisphenol A results in increased expression of AFP mRNA; bisphenol A results in increased expression of AFP proteinPMID:32145629
Afpaffects expressionISOAfp (Mus musculus)6480464CTDbisphenol A affects the expression of AFP mRNAPMID:14967926 PMID:30951980
Afpaffects expressionISOAFP (Homo sapiens)6480464CTDbisphenol A affects the expression of AFP mRNAPMID:30903817
Afpincreases expressionISOAfp (Mus musculus)6480464CTDbisphenol A results in increased expression of AFP mRNA; bisphenol A results in increased expression of AFP proteinPMID:26146954 PMID:34585602
Afpincreases expressionISOAFP (Homo sapiens)6480464CTDbisphenol A results in increased expression of AFP mRNAPMID:27271280
Afpmultiple interactionsISOAFP (Homo sapiens)6480464CTDIGF1 protein affects the reaction [bisphenol A results in increased expression of AFP mRNA]PMID:27271280
Go Back to source page   Continue to Ontology report