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Gene: Afp (alpha fetoprotein) Mus musculus
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Symbol: Afp
Name: alpha fetoprotein
RGD ID: 10116
Description: Predicted to have fatty acid binding activity and zinc ion binding activity. Involved in SMAD protein signal transduction; ovulation from ovarian follicle; and progesterone metabolic process. Localizes to cytoplasm and extracellular space. Is expressed in several structures, including amniotic fluid; egg cylinder; gut; liver and biliary system; and metanephros. Orthologous to human AFP (alpha fetoprotein); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha-1-fetoprotein; alpha-fetoglobulin; alpha-fetoprotein; alpha-foetoprotein
Orthologs:
Homo sapiens (human) : AFP (alpha fetoprotein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Afp (alpha-fetoprotein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AFP (alpha fetoprotein)
Canis lupus familiaris (dog) : AFP (alpha fetoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Afp (alpha fetoprotein)
Sus scrofa (pig) : AFP (alpha fetoprotein)
Chlorocebus sabaeus (African green monkey) : AFP (alpha fetoprotein)
Heterocephalus glaber (naked mole-rat) : Afp (alpha fetoprotein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39590,638,573 - 90,656,766 (+)NCBI
GRCm38590,490,714 - 90,508,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,490,737 - 90,508,907 (+)EnsemblGRCm38mm10GRCm38
MGSCv37590,919,740 - 90,937,933 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,565,937 - 91,584,106 (+)NCBImm8
Celera588,652,007 - 88,670,199 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Afp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10116
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.