GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Afp | decreases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in decreased expression of AFP mRNA | PMID:31150632 | Afp | increases expression | EXP | | 6480464 | CTD | Carbon Tetrachloride results in increased expression of AFP protein | PMID:16965562 PMID:61145 | Afp | multiple interactions | EXP | | 6480464 | CTD | 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; [2-Acetylaminofluorene co-treated with Carbon Tetrachloride] affects the expression of AFP protein; [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein; Aminoacetonitrile inhibits the reaction [Carbon Tetrachloride results in increased expression of AFP protein]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [Carbon Tetrachloride results in increased expression of AFP protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AFP mRNA]; Silymarin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; thymoquinone inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein] | PMID:11813887 PMID:28693887 PMID:28935427 PMID:29923357 PMID:31150632 PMID:61145 | Afp | increases expression | ISO | Afp (Mus musculus) | 6480464 | CTD | Carbon Tetrachloride results in increased expression of AFP mRNA; Carbon Tetrachloride results in increased expression of AFP protein | PMID:16965562 PMID:17668883 PMID:23288052 PMID:27339419 PMID:29987408 PMID:31919559 PMID:70250 | Afp | multiple interactions | ISO | Afp (Mus musculus) | 6480464 | CTD | Diethylnitrosamine promotes the reaction [Carbon Tetrachloride results in increased expression of AFP mRNA] | PMID:23288052 | |
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