Ugt2b17 (UDP glucuronosyltransferase family 2 member B17) - Rat Genome Database
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Gene: Ugt2b17 (UDP glucuronosyltransferase family 2 member B17) Rattus norvegicus
Analyze
Symbol: Ugt2b17
Name: UDP glucuronosyltransferase family 2 member B17
RGD ID: 708541
Description: Exhibits glucuronosyltransferase activity. Involved in several processes, including biphenyl catabolic process; cellular response to hormone stimulus; and cellular response to testosterone stimulus. Localizes to intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B11 (UDP glucuronosyltransferase family 2 member B11); and UGT2B17 (UDP glucuronosyltransferase family 2 member B17); PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucuronate interconversion pathway; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthaleneacetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2B1; liver UDP-glucuronosyltransferase, phenobarbital-inducible form; UDP glucuronosyltransferase 2 family, polypeptide B1; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP-glucuronosyltransferase 2B1; UDP-glucuronosyltransferase 2B4; UDPGT 2B1; UDPGTr-2; Udpgtr2; Ugt2b1
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21421,024,035 - 21,035,784 (+)NCBI
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01422,724,399 - 22,736,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01422,625,222 - 22,636,971 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41422,639,182 - 22,650,931 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11422,639,181 - 22,650,931 (+)NCBI
Celera1420,517,697 - 20,529,446 (+)NCBICelera
Cytogenetic Map14p21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthaleneacetic acid  (EXP)
1-naphthol  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-Ethylhexanoic acid  (EXP)
2-Ethylphenol  (EXP)
2-naphthol  (EXP)
2-nitrofluorene  (EXP)
3-Ethylphenol  (EXP)
3-phenylpropionic acid  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-ethylphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-methylumbelliferone  (EXP,ISO)
4-tert-butylphenol  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
amentoflavone  (ISO)
amiodarone  (EXP)
amitriptyline  (EXP)
ammonium chloride  (EXP)
androstane-3,17-diol  (ISO)
androsterone  (ISO)
aristolochic acid  (EXP)
Aroclor 1254  (EXP,ISO)
atrazine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
benzyl alcohol  (EXP)
bezafibrate  (EXP)
bicalutamide  (ISO)
biphenyl-4-ol  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (ISO)
calcitriol  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
chloramphenicol  (EXP)
chlorohydrocarbon  (EXP)
ciprofibrate  (EXP)
cisplatin  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
clomipramine  (EXP)
cortisol  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cyproconazole  (EXP)
daidzein  (ISO)
DDE  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP)
doxorubicin  (EXP)
elemental selenium  (EXP)
endosulfan  (EXP,ISO)
epoxiconazole  (EXP)
equol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
felbamate  (EXP)
fipronil  (EXP,ISO)
fluconazole  (EXP)
flumequine  (ISO)
flurbiprofen  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
fumonisin B1  (ISO)
gabapentin  (EXP)
genistein  (ISO)
glafenine  (EXP)
glutathione  (EXP)
hexachlorobenzene  (EXP)
hydratropic acid  (EXP)
ibuprofen  (EXP)
imipramine  (EXP)
indole-3-methanol  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
ketoconazole  (EXP)
ketoprofen  (EXP)
L-ascorbic acid  (EXP)
lansoprazole  (EXP)
Lasiocarpine  (EXP)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP)
lorcaserin  (ISO)
MeIQx  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
Mitotane  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-Vinyl-2-pyrrolidone  (EXP)
naproxen  (EXP)
nefazodone  (EXP)
nelfinavir  (EXP)
nimesulide  (EXP)
Nonylphenol  (EXP)
O-methyleugenol  (ISO)
oltipraz  (ISO)
omeprazole  (EXP)
orphenadrine  (EXP)
p-cresol  (EXP)
p-toluidine  (EXP)
pantoprazole  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
phenytoin  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pirprofen  (EXP)
poly(I:C)  (EXP)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
prochloraz  (EXP)
propiconazole  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quinolines  (EXP)
rabeprazole  (EXP)
rotenone  (EXP)
selenium atom  (EXP)
senecionine  (ISO)
tamoxifen  (EXP)
taurine  (EXP)
tert-butyl ethyl ether  (EXP)
Tesaglitazar  (EXP)
testosterone  (EXP,ISO)
Testosterone propionate  (EXP)
tetrachloromethane  (EXP,ISO)
triadimefon  (EXP)
trichloroethene  (ISO)
trifluralin  (EXP)
triphenyl phosphate  (EXP)
trovafloxacin  (EXP)
uranium atom  (EXP)
ursodeoxycholic acid  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:2113533   PMID:20308471   PMID:22579593  


Genomics

Comparative Map Data
Ugt2b17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21421,024,035 - 21,035,784 (+)NCBI
Rnor_6.0 Ensembl1422,724,070 - 22,825,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01422,724,399 - 22,736,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01422,625,222 - 22,636,971 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41422,639,182 - 22,650,931 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11422,639,181 - 22,650,931 (+)NCBI
Celera1420,517,697 - 20,529,446 (+)NCBICelera
Cytogenetic Map14p21NCBI
UGT2B17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl468,537,184 - 68,568,527 (-)EnsemblGRCh38hg38GRCh38
GRCh38468,537,173 - 68,576,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37469,402,902 - 69,434,245 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37469,402,891 - 69,442,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36469,085,497 - 69,116,840 (-)NCBINCBI36hg18NCBI36
Build 34469,231,670 - 69,263,011NCBI
Celera449,985,485 - 50,019,693 (-)NCBI
Cytogenetic Map4q13.2NCBI
CHM1_1469,439,588 - 69,470,934 (-)NCBICHM1_1
Ugt2b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39587,064,498 - 87,074,362 (-)NCBIGRCm39mm39
GRCm38586,916,639 - 86,926,503 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl586,916,638 - 86,926,530 (-)EnsemblGRCm38mm10GRCm38
MGSCv37587,345,664 - 87,355,528 (-)NCBIGRCm37mm9NCBIm37
MGSCv36587,991,200 - 88,001,064 (-)NCBImm8
Celera584,136,470 - 84,146,336 (-)NCBICelera
Cytogenetic Map5E1NCBI
LOC480777
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1359,138,348 - 59,222,802 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.11358,911,301 - 58,932,594 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1

Position Markers
AA945116  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map14307.7UniSTS
Cytogenetic Map14p21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14483323323004027Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14483323326466248Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14483323333040042Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141268042430155192Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141268061332593926Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141633698833163485Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141915991938289187Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141916189343957503Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141919154143957628Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)142018938665189386Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)142026622343957628Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)142145756566457565Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 23 23 23
Low 1 14 12 12 2 2 4 12 3 2
Below cutoff 8 16 2 18 2 6 6 7 17 6 7 6

Sequence


Reference Sequences
RefSeq Acc Id: NM_173295   ⟹   NP_775417
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21421,024,035 - 21,035,784 (+)NCBI
Rnor_6.01422,724,399 - 22,736,148 (+)NCBI
Rnor_5.01422,625,222 - 22,636,971 (+)NCBI
RGSC_v3.41422,639,182 - 22,650,931 (+)RGD
Celera1420,517,697 - 20,529,446 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_775417 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42310 (Get FASTA)   NCBI Sequence Viewer  
  AAA42313 (Get FASTA)   NCBI Sequence Viewer  
  EDL89826 (Get FASTA)   NCBI Sequence Viewer  
  P09875 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_775417   ⟸   NM_173295
- Peptide Label: precursor
- UniProtKB: P09875 (UniProtKB/Swiss-Prot)
- Sequence:
Protein Domains
UDPGT

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699257
Promoter ID:EPDNEW_R9782
Type:multiple initiation site
Name:Ugt2b17_2
Description:UDP glucuronosyltransferase family 2 member B17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R9783  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01422,724,389 - 22,724,449EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 22724490 22724491 G A snv COP/CrCrl (MCW & UW), FHH/EurMcwi (MCW), SR/JrHsd (MCW)
14 22724715 22724716 C T snv CDR, COP/CrCrl (MCW & UW)


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 22639273 22639274 G A snv FHH/EurMcwi (MCW), COP/CrCrl (MCW & UW), SR/JrHsd (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708541 AgrOrtholog
Ensembl Genes ENSRNOG00000001990 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002724 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000069054 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002724 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000089471 UniProtKB/TrEMBL
InterPro UDP_glucos_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:286954 UniProtKB/Swiss-Prot
NCBI Gene 286954 ENTREZGENE
Pfam UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB UGT2B4 RGD
PhenoGen Ugt2b17 PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUD3_RAT UniProtKB/TrEMBL
  P09875 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-09 Ugt2b17  UDP glucuronosyltransferase family 2 member B17  Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-02-04 Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-03-11 Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Ugt2b17  UDP glucuronosyltransferase 2 family, polypeptide B17  Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ugt2b1  UDP glucuronosyltransferase 2 family, polypeptide B1  Udpgtr2  liver UDP-glucuronosyltransferase, phenobarbital-inducible form  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 Udpgtr2        Symbol and Name status set to provisional 70820 PROVISIONAL