Ugt2b (UDP glycosyltransferase 2 family, polypeptide B) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ugt2b (UDP glycosyltransferase 2 family, polypeptide B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ugt2b
Name: UDP glycosyltransferase 2 family, polypeptide B
RGD ID: 3936
Description: ENCODES a protein that exhibits glucuronosyltransferase activity; PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucuronate interconversion pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; FOUND IN endoplasmic reticulum membrane (inferred); integral component of membrane (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,4,7,8-Pentachlorodibenzofuran
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-hydroxyandrogen specific; 3-hydroxyandrogen-specific UDPGT; Androsterone UDP-glucuronosyltransferase; LOC688226; RLUG23; UDP glucuronosyltransferase; UDP-glucuronosyltransferase 2B2; UDPGT 2B2; UDPGTr-4; Ugt2b2
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21420,630,572 - 20,665,062 (+)NCBI
Rnor_6.0 Ensembl1422,375,955 - 22,534,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01422,323,542 - 22,344,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41422,154,370 - 22,178,222 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11422,066,518 - 22,177,852 (+)NCBI
Cytogenetic Map14p22-p21.2NCBI


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1909872   PMID:7492328   PMID:12477932   PMID:17435758   PMID:23230277  


Genomics

Position Markers
RH127922  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01422,157,582 - 22,157,799NCBIRnor6.0
Rnor_6.01422,438,390 - 22,438,607NCBIRnor6.0
Rnor_5.01422,344,386 - 22,344,603UniSTSRnor5.0
Rnor_5.01422,071,655 - 22,071,872UniSTSRnor5.0
RGSC_v3.41422,179,529 - 22,179,746UniSTSRGSC3.4
RGSC_v3.41422,178,177 - 22,179,746UniSTSRGSC3.4
Cytogenetic Map14p22-p21.2UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:46
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000052369
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_031533   ⟹   NP_113721
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,630,591 - 20,651,409 (+)NCBI
Rnor_5.01422,323,542 - 22,344,064 (+)NCBI
RGSC_v3.41422,154,370 - 22,178,222 (+)RGD
Sequence:
RefSeq Acc Id: XM_039091621   ⟹   XP_038947549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,630,572 - 20,665,062 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113721   ⟸   NM_031533
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_038947549   ⟸   XM_039091621
- Peptide Label: isoform X1
Protein Domains
UDPGT

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
14 22323705 22323706 G T snv Crl:SD (UDEL)
14 22323800 22323801 A C snv SBH/Ygl (MCW), FHL/EurMcwi (MCW), SBN/Ygl (MCW), SR/JrHsd (MCW), SS/JrHsdMcwi (MCW), COP/CrCrl (MCW & UW), SDLEF7/Barth (UDEL), Crl:SD (UDEL)
14 22324124 22324125 G T snv LE/Stm (KyushuU)
14 22342303 22342304 A T snv LEC/Tj (KyushuU), BUF/MNa (KyushuU), Crl:SD (UDEL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSRNOG00000046540 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000043239 UniProtKB/TrEMBL
  ENSRNOP00000063270 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052369 UniProtKB/TrEMBL
  ENSRNOT00000063915 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7370057 IMAGE-MGC_LOAD
InterPro UDP_glucos_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UDP_glycos_trans_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24862 UniProtKB/TrEMBL
MGC_CLONE MGC:108656 IMAGE-MGC_LOAD
NCBI Gene 24862 ENTREZGENE
Pfam UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ugt2b PhenoGen
PROSITE UDPGT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1XF83_RAT UniProtKB/TrEMBL
  F1LM22_RAT UniProtKB/TrEMBL
  F1M3E3_RAT UniProtKB/TrEMBL
  P08541 ENTREZGENE
  Q5EBC8_RAT UniProtKB/TrEMBL
  UD2B2_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-29 Ugt2b  UDP glycosyltransferase 2 family, polypeptide B  LOC688226  similar to UDP-glucuronosyltransferase 2B2 precursor (UDPGT) (3-hydroxyandrogen specific) (UDPGTr-4) (RLUG23)  Data Merged 737654 PROVISIONAL
2006-11-20 LOC688226  similar to UDP-glucuronosyltransferase 2B2 precursor (UDPGT) (3-hydroxyandrogen specific) (UDPGTr-4) (RLUG23)      Symbol and Name status set to provisional 70820 PROVISIONAL
2003-04-09 Ugt2b  UDP glycosyltransferase 2 family, polypeptide B  Ugt2b2  Androsterone UDP-glucuronosyltransferase  Symbol and Name updated 629477 APPROVED
2002-06-10 Ugt2b2  Androsterone UDP-glucuronosyltransferase      Symbol and Name status set to approved 70586 APPROVED