Sult1e1 (sulfotransferase family 1E member 1) - Rat Genome Database

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Gene: Sult1e1 (sulfotransferase family 1E member 1) Rattus norvegicus
Analyze
Symbol: Sult1e1
Name: sulfotransferase family 1E member 1
RGD ID: 3776
Description: Enables estrone sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen catabolic process; and ethanol catabolic process. Predicted to act upstream of or within female pregnancy. Predicted to be located in cytosol and nuclear membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in breast cancer and endometrial cancer. Orthologous to human SULT1E1 (sulfotransferase family 1E member 1); PARTICIPATES IN estradiol biosynthetic pathway; paracetamol pharmacokinetics pathway; sulfite oxidase deficiency pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EST-1; EST-2; EST-3; EST-6; estrogen sulfotransferase; estrogen sulfotransferase, isoform 1; estrogen sulfotransferase, isoform 3; estrone sulfotransferase; ESTSUL; rEST-6; ST1E1; Ste; Ste1; ste2; sulfotransferase 1E1; sulfotransferase family 1E, estrogen-preferring, member 1; sulfotransferase family 1E, member 1; sulfotransferase, estrogen preferring; sulfotransferase, estrogen-preferring
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21420,422,324 - 20,439,562 (+)NCBI
Rnor_6.0 Ensembl1422,072,024 - 22,089,248 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01422,070,861 - 22,089,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01421,985,847 - 22,004,150 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1419,831,652 - 19,842,299 (+)NCBICelera
Cytogenetic Map14p21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-ropivacaine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-hydroxy-17beta-estradiol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
3-Hydroxybenzo[a]pyrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-nitrophenol  (ISO)
4-nonylphenol  (ISO)
acetonitrile  (ISO)
adenosine 3',5'-bismonophosphate  (ISO)
aflatoxin B1  (ISO)
Aloe emodin  (ISO)
ammonium chloride  (EXP)
apigenin  (ISO)
Aroclor 1254  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene-7,8-dione  (ISO)
beta-naphthoflavone  (ISO)
bifenthrin  (EXP)
biochanin A  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bosentan  (ISO)
butylated hydroxyanisole  (ISO)
Butylparaben  (EXP)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
choline  (ISO)
chrysin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
colforsin daropate hydrochloride  (ISO)
coumarin  (EXP)
cyanocob(III)alamin  (ISO)
dehydroepiandrosterone  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
dienestrol  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
estriol  (ISO)
estrone  (ISO)
estrone 3-sulfate  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (EXP)
fipronil  (ISO)
folic acid  (ISO)
fulvestrant  (EXP)
furan  (EXP)
genistein  (ISO)
glafenine  (EXP)
glycine betaine  (ISO)
glyphosate  (EXP)
graphene oxide  (ISO)
Heliotrine  (ISO)
hexachlorobenzene  (EXP)
hexestrol  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
indole-3-methanol  (EXP)
kojic acid  (EXP,ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
meclofenamic acid  (ISO)
methotrexate  (ISO)
mifepristone  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
orphenadrine  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
Propiverine  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (EXP)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulindac  (EXP,ISO)
sunitinib  (ISO)
tebuconazole  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
triadimefon  (ISO)
triclosan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
urethane  (ISO)
vitamin E  (EXP)
zaragozic acid A  (ISO)
zearalenone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cellular_component  (ND)
cytoplasm  (IBA,ISO)
cytosol  (ISO,ISS)
nuclear membrane  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:1299062   PMID:9348232   PMID:9765259   PMID:10519119   PMID:11884392   PMID:12173467   PMID:12477932   PMID:12765521   PMID:15685171   PMID:18054434   PMID:19548878   PMID:20056724  
PMID:23207770   PMID:24567372  


Genomics

Comparative Map Data
Sult1e1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21420,422,324 - 20,439,562 (+)NCBI
Rnor_6.0 Ensembl1422,072,024 - 22,089,248 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01422,070,861 - 22,089,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01421,985,847 - 22,004,150 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1419,831,652 - 19,842,299 (+)NCBICelera
Cytogenetic Map14p21NCBI
SULT1E1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl469,841,212 - 69,860,145 (-)EnsemblGRCh38hg38GRCh38
GRCh38469,841,212 - 69,860,151 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37470,706,930 - 70,725,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36470,741,519 - 70,760,459 (-)NCBINCBI36hg18NCBI36
Build 34470,887,690 - 70,906,630NCBI
Celera468,060,253 - 68,079,193 (-)NCBI
Cytogenetic Map4q13.3NCBI
HuRef466,504,780 - 66,523,720 (-)NCBIHuRef
CHM1_1470,743,366 - 70,762,280 (-)NCBICHM1_1
Sult1e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39587,723,827 - 87,739,470 (-)NCBIGRCm39mm39
GRCm39 Ensembl587,723,828 - 87,739,453 (-)Ensembl
GRCm38587,575,968 - 87,591,611 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl587,575,969 - 87,591,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv37588,004,993 - 88,020,636 (-)NCBIGRCm37mm9NCBIm37
MGSCv36588,650,530 - 88,666,155 (-)NCBImm8
Celera584,792,542 - 84,808,207 (-)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
SULT1E1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1460,714,305 - 60,733,229 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0454,377,681 - 54,396,619 (+)NCBIMhudiblu_PPA_v0panPan3
LOC482182
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11359,323,430 - 59,343,745 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1359,052,730 - 59,072,999 (-)NCBI
ROS_Cfam_1.01360,119,719 - 60,140,008 (-)NCBI
UMICH_Zoey_3.11359,734,248 - 59,754,528 (-)NCBI
UNSW_CanFamBas_1.01359,195,062 - 59,214,797 (-)NCBI
UU_Cfam_GSD_1.01360,339,614 - 60,359,890 (-)NCBI
SULT1E1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1866,811,536 - 66,838,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SULT1E1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1718,313,510 - 18,330,768 (-)NCBI
Vero_WHO_p1.0NW_0236660844,599,800 - 4,616,560 (+)NCBI

Position Markers
D14Arb6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21420,439,207 - 20,439,526 (+)MAPPER
Rnor_6.01422,088,911 - 22,089,228NCBIRnor6.0
Rnor_5.01422,003,797 - 22,004,114UniSTSRnor5.0
RGSC_v3.41421,965,205 - 21,965,523RGDRGSC3.4
RGSC_v3.41421,965,206 - 21,965,523UniSTSRGSC3.4
RGSC_v3.11421,965,205 - 21,965,523RGD
Celera1419,841,948 - 19,842,265UniSTS
FHH x ACI Map1421.7599RGD
FHH x ACI Map1421.7599UniSTS
Cytogenetic Map14p21UniSTS
Cytogenetic Map14p21.3-p21.2UniSTS
D14Wox31  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21420,421,607 - 20,421,896 (+)MAPPER
Rnor_6.01422,071,307 - 22,071,596NCBIRnor6.0
Rnor_5.01421,986,193 - 21,986,482UniSTSRnor5.0
RGSC_v3.41421,947,758 - 21,948,047UniSTSRGSC3.4
Cytogenetic Map14p21.3-p21.2UniSTS
Cytogenetic Map14p21UniSTS
D14Wox19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21420,439,378 - 20,439,524 (+)MAPPER
Rnor_6.01422,089,082 - 22,089,226NCBIRnor6.0
Rnor_5.01422,003,968 - 22,004,112UniSTSRnor5.0
RGSC_v3.41421,965,377 - 21,965,521UniSTSRGSC3.4
Celera1419,842,119 - 19,842,263UniSTS
Cytogenetic Map14p21UniSTS
Cytogenetic Map14p21.3-p21.2UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14127597761Rat
619619Rf4Renal disease susceptibility QTL 44.10.002total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14134403399Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14141333960Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14141333960Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14142766285Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14483323323004027Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14483323326466248Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14483323333040042Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14975643572854397Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin141053997755539977Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)141053997755539977Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)141072926861873323Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141268042430155192Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1412680424106641756Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141268061332593926Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141633698833163485Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141915991938289187Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141916189343957503Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141919154143957628Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)142018938665189386Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)142026622343957628Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)142145756566457565Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 8 5
Medium 4 4 4 1
Low 7 2 4 2 1 1 2 2 16 4 1
Below cutoff 1 6 21 10 13 10 5 7 9 12 16 4 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ131835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ298109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ306228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ312318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M86758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S76489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S76490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U50204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U50205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002680   ⟹   ENSRNOP00000002680
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1422,072,024 - 22,089,248 (+)Ensembl
RefSeq Acc Id: NM_012883   ⟹   NP_037015
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21420,422,324 - 20,439,562 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: ENSRNOP00000002680   ⟸   ENSRNOT00000002680
RefSeq Acc Id: NP_037015   ⟸   NM_012883
- Sequence:
Protein Domains
Sulfotransfer_1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699249
Promoter ID:EPDNEW_R9774
Type:multiple initiation site
Name:Sult1e1_1
Description:sulfotransferase family 1E member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01422,072,015 - 22,072,075EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3776 AgrOrtholog
Ensembl Genes ENSRNOG00000001957 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002680 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002680 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7323209 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:360268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:108739 IMAGE-MGC_LOAD
NCBI Gene 360268 ENTREZGENE
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB SULT1E1 RGD
PhenoGen Sult1e1 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P49889 ENTREZGENE
  P49890 ENTREZGENE
  P52844 ENTREZGENE
  P52845 ENTREZGENE
  Q99ND5_RAT UniProtKB/TrEMBL
  ST1E1_RAT UniProtKB/Swiss-Prot
  ST1E2_RAT UniProtKB/Swiss-Prot
  ST1E3_RAT UniProtKB/Swiss-Prot
  STE2_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9QWS0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-25 Sult1e1  sulfotransferase family 1E member 1  ste2  estrogen sulfotransferase  Data Merged 737654 PROVISIONAL
2015-11-12 Sult1e1  sulfotransferase family 1E member 1  Sult1e1  sulfotransferase family 1E, estrogen-preferring, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Sult1e1  sulfotransferase family 1E, estrogen-preferring, member 1  Sult1e1  sulfotransferase family 1E, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Sult1e1  sulfotransferase family 1E, member 1  Ste  sulfotransferase, estrogen preferring  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 ste2  estrogen sulfotransferase      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Ste  sulfotransferase, estrogen preferring      Symbol and Name status set to approved 70586 APPROVED
2001-07-23 Ste  Estrogen sulfotransferase      Name withdrawn 67952 WITHDRAWN
2001-07-23 Ste  sulfotransferase, estrogen preferring      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 1299062