Gene: Ppef2 (protein phosphatase with EF-hand domain 2) Rattus norvegicus
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Symbol: Ppef2
Name: protein phosphatase with EF-hand domain 2
Description: ENCODES a protein that exhibits Hsp70 protein binding (ortholog); Hsp90 protein binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN negative regulation of MAPK cascade (ortholog); negative regulation of peptidyl-threonine phosphorylation (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; cadmium dichloride; lead diacetate
AGR Description: Predicted to have heat shock protein binding activity, mitogen-activated protein kinase kinase kinase binding activity, and protein serine/threonine phosphatase activity; predicted to be involved in negative regulation of MAPK cascade and negative regulation of peptidyl-threonine phosphorylation; predicted to localize to the cytosol and nucleus; orthologous to human PPEF2 (protein phosphatase with EF-hand domain 2).
Merged Description: Predicted to have heat shock protein binding activity, mitogen-activated protein kinase kinase kinase binding activity, and protein serine/threonine phosphatase activity; predicted to be involved in negative regulation of MAPK cascade and negative regulation of peptidyl-threonine phosphorylation; predicted to localize to the cytosol and nucleus; orthologous to human PPEF2 (protein phosphatase with EF-hand domain 2); INTERACTS WITH 1,2-dimethylhydrazine; cadmium dichloride; lead diacetate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC305246; protein phosphatase, EF hand calcium-binding domain 2; serine/threonine-protein phosphatase with EF-hands 2
Orthologs:
Homo sapiens (human) : PPEF2 (protein phosphatase with EF-hand domain 2)  HGNC  Alliance
Mus musculus (house mouse) : Ppef2 (protein phosphatase, EF hand calcium-binding domain 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppef2 (protein phosphatase with EF-hand domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PPEF2 (protein phosphatase with EF-hand domain 2)
Canis lupus familiaris (dog) : PPEF2 (protein phosphatase with EF-hand domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppef2 (protein phosphatase with EF-hand domain 2)
Sus scrofa (pig) : PPEF2 (protein phosphatase with EF-hand domain 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01417,306,825 - 17,333,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01417,220,015 - 17,254,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,359,298 - 17,392,820 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11417,366,155 - 17,392,304 (+)NCBI
Celera1415,191,812 - 15,226,681 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ppef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307093
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.