Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CCNI mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CCNI mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | Ccni (Mus musculus) | 6480464 | Estradiol affects the expression of CCNI mRNA | CTD | PMID:15598610 | 17beta-estradiol | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | Estradiol affects the expression of CCNI mRNA | CTD | PMID:21826169 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCNI mRNA | CTD | PMID:18796159 and PMID:19770486 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNI mRNA more ... | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of CCNI mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CCNI mRNA | CTD | PMID:30047161 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CCNI mRNA | CTD | PMID:36843608 | acrolein | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCNI mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CCNI mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | CCNI (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CCNI gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCNI mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CCNI mRNA | CTD | PMID:32699268 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of CCNI mRNA | CTD | PMID:30047161 | antirheumatic drug | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CCNI mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of CCNI mRNA | CTD | PMID:23650126 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | benzo[a]pyrene diol epoxide I | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | bisphenol A affects the expression of CCNI mRNA | CTD | PMID:21826169 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCNI mRNA | CTD | PMID:33296240 | bisphenol A | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | bisphenol A results in increased expression of CCNI mRNA and bisphenol A results in increased expression of CCNI protein | CTD | PMID:29275510 and PMID:33376534 | bisphenol A | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNI mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CCNI mRNA | CTD | PMID:30816183 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CCNI mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of CCNI mRNA | CTD | PMID:28628672 | carbon nanotube | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | Nanotubes and Carbon results in increased expression of CCNI mRNA | CTD | PMID:15585362 | carbon nanotube | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chloropicrin | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | chloropicrin affects the expression of CCNI mRNA | CTD | PMID:26352163 | clofibrate | increases expression | ISO | Ccni (Mus musculus) | 6480464 | Clofibrate results in increased expression of CCNI mRNA | CTD | PMID:17585979 | clofibrate | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of CCNI mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CCNI mRNA] | CTD | PMID:17585979 | cobalt dichloride | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of CCNI mRNA | CTD | PMID:19320972 | cobalt dichloride | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of CCNI mRNA | CTD | PMID:19376846 | coumestrol | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of CCNI mRNA | CTD | PMID:19167446 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CCNI mRNA | CTD | PMID:26577399 | cyclosporin A | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CCNI mRNA | CTD | PMID:20106945 and PMID:27989131 | dexamethasone | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNI mRNA more ... | CTD | PMID:28628672 | Di-n-octyl phthalate | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | di-n-octyl phthalate results in decreased expression of CCNI mRNA | CTD | PMID:37810885 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of CCNI mRNA | CTD | PMID:22546817 | dioxygen | increases expression | ISO | Ccni (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of CCNI mRNA | CTD | PMID:22629407 | dioxygen | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CCNI mRNA and Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of CCNI mRNA] | CTD | PMID:22629407 and PMID:30529165 | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of CCNI mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCNI mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CCNI mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CCNI mRNA | CTD | PMID:29391264 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of CCNI mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Folic Acid results in decreased expression of CCNI mRNA | CTD | PMID:25629700 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CCNI mRNA | CTD | PMID:22061828 and PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of CCNI mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CCNI mRNA more ... | CTD | PMID:28628672 | menadione | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of CCNI mRNA | CTD | PMID:20044591 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CCNI mRNA | CTD | PMID:30047161 | ozone | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CCNI mRNA more ... | CTD | PMID:32699268 | paracetamol | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Acetaminophen results in decreased expression of CCNI mRNA | CTD | PMID:17585979 | paracetamol | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CCNI mRNA | CTD | PMID:29067470 | paracetamol | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of CCNI mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CCNI mRNA] | CTD | PMID:17585979 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CCNI mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | Ccni (Mus musculus) | 6480464 | Phenobarbital affects the expression of CCNI mRNA | CTD | PMID:23091169 | potassium dichromate | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of CCNI mRNA | CTD | PMID:23608068 | progesterone | affects expression | ISO | Ccni (Mus musculus) | 6480464 | Progesterone affects the expression of CCNI mRNA | CTD | PMID:17251523 | SB 431542 | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCNI mRNA | CTD | PMID:27188386 | sirolimus | multiple interactions | ISO | Ccni (Mus musculus) | 6480464 | Sirolimus inhibits the reaction [IL2 protein results in decreased expression of CCNI mRNA] | CTD | PMID:11355896 | sodium arsenite | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CCNI mRNA | CTD | PMID:34032870 | sodium fluoride | increases expression | ISO | Ccni (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of CCNI mRNA | CTD | PMID:21340527 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of CCNI mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | CCNI (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CCNI mRNA | CTD | PMID:31533062 | titanium dioxide | increases expression | ISO | Ccni (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CCNI mRNA | CTD | PMID:23557971 and PMID:29264374 | titanium dioxide | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of CCNI mRNA | CTD | PMID:27760801 | trichloroethene | decreases expression | ISO | Ccni (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of CCNI mRNA | CTD | PMID:19448997 | triptonide | increases expression | ISO | Ccni (Mus musculus) | 6480464 | triptonide results in increased expression of CCNI mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | CCNI (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CCNI mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | CCNI (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CCNI gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CCNI mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | CCNI (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCNI mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | CCNI (Homo sapiens) | 6480464 | vorinostat results in decreased expression of CCNI mRNA | CTD | PMID:27188386 | |