Gene: Lrrc8c (leucine rich repeat containing 8 VRAC subunit C) Rattus norvegicus
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Symbol: Lrrc8c
Name: leucine rich repeat containing 8 VRAC subunit C
Description: Contributes to volume-sensitive anion channel activity; involved in aspartate transmembrane transport, cellular response to osmotic stress, and taurine transport; localizes to the integral component of plasma membrane and ion channel complex; orthologous to human LRRC8C (leucine rich repeat containing 8 VRAC subunit C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leucine rich repeat containing 8 family, member C; leucine-rich repeat-containing protein 8C; LOC289443; MGC112653; RGD1306585; similar to hypothetical protein AD158; volume-regulated anion channel subunit LRRC8C
Orthologs:
Homo sapiens (human) : LRRC8C (leucine rich repeat containing 8 VRAC subunit C)  HGNC  Alliance
Mus musculus (house mouse) : Lrrc8c (leucine rich repeat containing 8 family, member C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrc8c (leucine rich repeat containing 8 VRAC subunit C)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRC8C (leucine rich repeat containing 8 VRAC subunit C)
Canis lupus familiaris (dog) : LRRC8C (leucine rich repeat containing 8 VRAC subunit C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrc8c (leucine rich repeat containing 8 VRAC subunit C)
Sus scrofa (pig) : LRRC8C (leucine rich repeat containing 8 VRAC subunit C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0145,283,655 - 5,378,738 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0145,274,372 - 5,369,435 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4145,306,227 - 5,393,820 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1145,306,353 - 5,393,463 (-)NCBI
Celera144,390,675 - 4,477,877 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Lrrc8c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306585
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.