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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hsd17b13 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of HSD17B13 mRNA] | CTD | PMID:31150632 | Hsd17b13 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Hsd17b13 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HSD17B13 mRNA | CTD | PMID:36331819 | Hsd17b13 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of HSD17B13 mRNA | CTD | PMID:22206623 | Hsd17b13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of HSD17B13 mRNA | CTD | PMID:22298810 | Hsd17b13 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HSD17B13 mRNA | CTD | PMID:22298810 | Hsd17b13 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Hsd17b13 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of HSD17B13 mRNA | CTD | PMID:21346803 | Hsd17b13 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of HSD17B13 mRNA | CTD | PMID:25825206 | Hsd17b13 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of HSD17B13 mRNA | CTD | PMID:33354967 | Hsd17b13 | Rat | atrazine | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Atrazine results in decreased expression of HSD17B13 mRNA | CTD | PMID:23376530 | Hsd17b13 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of HSD17B13 gene | CTD | PMID:35440735 | Hsd17b13 | Rat | benzo[a]pyrene | decreases methylation | ISO | HSD17B13 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of HSD17B13 promoter | CTD | PMID:27901495 | Hsd17b13 | Rat | benzo[a]pyrene | affects methylation | ISO | HSD17B13 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of HSD17B13 intron | CTD | PMID:30157460 | Hsd17b13 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of HSD17B13 mRNA | CTD | PMID:25181051 | Hsd17b13 | Rat | bisphenol A | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of HSD17B13 mRNA | CTD | PMID:33221593 | Hsd17b13 | Rat | bisphenol A | increases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | bisphenol A results in increased expression of HSD17B13 mRNA | CTD | PMID:30245210 | Hsd17b13 | Rat | bisphenol A | increases methylation | ISO | Hsd17b13 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of HSD17B13 promoter | CTD | PMID:27312807 | Hsd17b13 | Rat | bisphenol F | increases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | bisphenol F results in increased expression of HSD17B13 mRNA | CTD | PMID:38685157 | Hsd17b13 | Rat | buta-1,3-diene | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of HSD17B13 mRNA | CTD | PMID:29038090 | Hsd17b13 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of HSD17B13 promoter | CTD | PMID:22457795 | Hsd17b13 | Rat | carbon nanotube | increases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of HSD17B13 mRNA | CTD | PMID:25620056 | Hsd17b13 | Rat | ciguatoxin CTX1B | affects expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of HSD17B13 mRNA | CTD | PMID:18353800 | Hsd17b13 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HSD17B13 mRNA | CTD | PMID:17602206 | Hsd17b13 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of HSD17B13 mRNA | CTD | PMID:26577399 | Hsd17b13 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of HSD17B13 mRNA | CTD | PMID:23640034 | Hsd17b13 | Rat | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of HSD17B13 mRNA | CTD | PMID:25152437 | Hsd17b13 | Rat | enilconazole | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | enilconazole results in decreased expression of HSD17B13 mRNA | CTD | PMID:30853599 | Hsd17b13 | Rat | entacapone | affects binding | EXP | | 6480464 | entacapone binds to HSD17B13 protein | CTD | PMID:19783845 | Hsd17b13 | Rat | fipronil | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | [fipronil co-treated with DEET] results in decreased expression of HSD17B13 mRNA | CTD | PMID:27091632 | Hsd17b13 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of HSD17B13 mRNA | CTD | PMID:24793618 | Hsd17b13 | Rat | glyphosate | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of HSD17B13 protein | CTD | PMID:36173347 | Hsd17b13 | Rat | Heliotrine | increases expression | EXP | | 6480464 | heliotrine results in increased expression of HSD17B13 mRNA | CTD | PMID:32419051 | Hsd17b13 | Rat | Lasiocarpine | increases expression | EXP | | 6480464 | lasiocarpine results in increased expression of HSD17B13 mRNA | CTD | PMID:32419051 | Hsd17b13 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of HSD17B13 mRNA | CTD | PMID:24136188 | Hsd17b13 | Rat | N,N-diethyl-m-toluamide | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | [fipronil co-treated with DEET] results in decreased expression of HSD17B13 mRNA | CTD | PMID:27091632 | Hsd17b13 | Rat | N,N-diethyl-m-toluamide | increases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | DEET results in increased expression of HSD17B13 mRNA | CTD | PMID:27091632 | Hsd17b13 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HSD17B13 mRNA | CTD | PMID:17602206 | Hsd17b13 | Rat | NAD zwitterion | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of HSD17B13 protein | CTD | PMID:25526675 | Hsd17b13 | Rat | NAD(+) | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | NAD binds to and results in increased activity of HSD17B13 protein | CTD | PMID:25526675 | Hsd17b13 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of HSD17B13 mRNA | CTD | PMID:22110744 | Hsd17b13 | Rat | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of HSD17B13 mRNA | CTD | PMID:24136188 | Hsd17b13 | Rat | perfluorononanoic acid | decreases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of HSD17B13 mRNA | CTD | PMID:32588087 | Hsd17b13 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of HSD17B13 mRNA | CTD | PMID:32588087 | Hsd17b13 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Hsd17b13 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of HSD17B13 mRNA | CTD | PMID:36331819 | Hsd17b13 | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of HSD17B13 protein | CTD | PMID:34958885 | Hsd17b13 | Rat | perfluorooctanoic acid | decreases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of HSD17B13 mRNA | CTD | PMID:32588087 | Hsd17b13 | Rat | permethrin | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Permethrin analog results in decreased expression of HSD17B13 mRNA | CTD | PMID:21745691 | Hsd17b13 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of HSD17B13 mRNA | CTD | PMID:19162173 | Hsd17b13 | Rat | potassium dichromate | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of HSD17B13 mRNA | CTD | PMID:23608068 | Hsd17b13 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of HSD17B13 mRNA | CTD | PMID:28903501 | Hsd17b13 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of HSD17B13 mRNA | CTD | PMID:28374803 | Hsd17b13 | Rat | sodium arsenite | decreases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of HSD17B13 mRNA | CTD | PMID:29301061 | Hsd17b13 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of HSD17B13 mRNA | CTD | PMID:22110744 | Hsd17b13 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of HSD17B13 mRNA | CTD | PMID:19281266 | Hsd17b13 | Rat | tetrachloroethene | increases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Tetrachloroethylene results in increased expression of HSD17B13 mRNA | CTD | PMID:28973375 | Hsd17b13 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of HSD17B13 mRNA | CTD | PMID:31150632 | Hsd17b13 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of HSD17B13 mRNA] | CTD | PMID:31150632 | Hsd17b13 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of HSD17B13 mRNA | CTD | PMID:34492290 | Hsd17b13 | Rat | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to HSD17B13 protein | CTD | PMID:19783845 | Hsd17b13 | Rat | trichloroethene | increases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of HSD17B13 mRNA | CTD | PMID:28973375 | Hsd17b13 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of HSD17B13 mRNA | CTD | PMID:33387578 | Hsd17b13 | Rat | triphenyl phosphate | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | triphenyl phosphate results in decreased expression of HSD17B13 mRNA | CTD | PMID:26049154 and PMID:26183808 | Hsd17b13 | Rat | triphenyl phosphate | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | triphenyl phosphate inhibits the reaction [CGB3 protein results in increased expression of HSD17B13 mRNA] | CTD | PMID:26049154 | Hsd17b13 | Rat | tris(2-chloroethyl) phosphate | multiple interactions | ISO | HSD17B13 (Homo sapiens) | 6480464 | tris(chloroethyl)phosphate inhibits the reaction [CGB3 protein results in increased expression of HSD17B13 mRNA] | CTD | PMID:26049154 | Hsd17b13 | Rat | tris(2-chloroethyl) phosphate | decreases expression | ISO | Hsd17b13 (Mus musculus) | 6480464 | tris(chloroethyl)phosphate results in decreased expression of HSD17B13 mRNA | CTD | PMID:26049154 | Hsd17b13 | Rat | troglitazone | decreases expression | ISO | HSD17B13 (Homo sapiens) | 6480464 | troglitazone results in decreased expression of HSD17B13 mRNA | CTD | PMID:25572481 | Hsd17b13 | Rat | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of HSD17B13 mRNA | CTD | PMID:24136188 | Hsd17b13 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of HSD17B13 gene | CTD | PMID:31079544 | |