Mgst3l1 (microsomal glutathione S-transferase 3 like 1) - Rat Genome Database

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Gene: Mgst3l1 (microsomal glutathione S-transferase 3 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Mgst3l1 (Ensembl: RGD1561381)
Name: microsomal glutathione S-transferase 3 like 1 (Ensembl:similar to microsomal glutathione S-transferase 3)
RGD ID: 1561381
Description: Predicted to be involved in cellular oxidant detoxification and leukotriene metabolic process. Predicted to be located in membrane; INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutathione S-transferase 3, mitochondrial-like; LOC498340; microsomal glutathione S-transferase 3-like; RGD1561381; similar to microsomal glutathione S-transferase 3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,809,202 - 19,811,522 (+)NCBIGRCr8
mRatBN7.21419,525,509 - 19,526,128 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,525,558 - 19,526,016 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01421,163,791 - 21,164,435 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01421,073,611 - 21,074,255 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41421,105,801 - 21,106,259 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1418,864,156 - 18,864,800 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Mgst3l1
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:42
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000004798
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062228035204Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141103081230320092Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141487516830883947Rat
631528Scl11Serum cholesterol level QTL 114.9blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)141757341219726296Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)141759376142336881Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141762256142337007Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141863134542337007Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000004798   ⟹   ENSRNOP00000096456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1419,525,558 - 19,526,016 (+)Ensembl
Rnor_6.0 Ensembl1421,163,840 - 21,164,295 (+)Ensembl
RefSeq Acc Id: XM_063273814   ⟹   XP_063129884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81419,809,202 - 19,811,522 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063129884 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089717.1
  ENSRNOP00000096456.1
RefSeq Acc Id: ENSRNOP00000096456   ⟸   ENSRNOT00000004798
RefSeq Acc Id: XP_063129884   ⟸   XM_063273814
- UniProtKB: A0A8I6AAX9 (UniProtKB/TrEMBL),   A0A8I6AQS8 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-16161 BioCyc
Ensembl Genes ENSRNOG00000003606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000004245 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004798.7 UniProtKB/TrEMBL
  ENSRNOT00000097875.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/TrEMBL
InterPro MAPEG-like_dom_sf UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/TrEMBL
NCBI Gene 498340 ENTREZGENE
PANTHER MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE 3 UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/TrEMBL
PhenoGen Mgst3l1 PhenoGen
RatGTEx ENSRNOG00000003606 RatGTEx
  ENSRNOG00000004245 RatGTEx
Superfamily-SCOP SSF161084 UniProtKB/TrEMBL
UniProt A0A8I6AAX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQS8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Mgst3l1  microsomal glutathione S-transferase 3 like 1  RGD1561381  similar to microsomal glutathione S-transferase 3  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1561381  similar to microsomal glutathione S-transferase 3   RGD1561381_predicted  similar to microsomal glutathione S-transferase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561381_predicted  similar to microsomal glutathione S-transferase 3 (predicted)  LOC498340  similar to microsomal glutathione S-transferase 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498340  similar to microsomal glutathione S-transferase 3      Symbol and Name status set to provisional 70820 PROVISIONAL